anti-CLEC7A (CLEC7A) 抗体产品概述

Full name:
anti-C-Type Lectin Domain Family 7, Member A 抗体 (CLEC7A)
在www.antibodies-online.cn可供221 C-Type Lectin Domain Family 7, Member A (CLEC7A) 抗体的22不同的供货商。 再加上,我们可以发CLEC7A 试剂盒 (21)CLEC7A 蛋白 (14)和数多这个蛋白质的别的产品。 总共267 CLEC7A产品已列进来了。
别名:
beta-GR, BGR, CANDF4, CLEC7A, Clec7b, CLECSF12, DECTIN1, RGD1565140
列出全部抗体 基因 基因ID UniProt
CLEC7A 56644 Q6QLQ4
CLEC7A 64581 Q9BXN2
CLEC7A 502902  

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  1. Mouse (Murine) Monoclonal CLEC7A Primary Antibody for Func, FACS - ABIN181895 : Reid, Montoya, Taylor, Borrow, Gordon, Brown, Wong: Expression of the beta-glucan receptor, Dectin-1, on murine leukocytes in situ correlates with its function in pathogen recognition and reveals potential roles in leukocyte interactions. in Journal of leukocyte biology 2004 (PubMed)
    Show all 7 references for 181895

  2. Human Monoclonal CLEC7A Primary Antibody for FACS - ABIN4897736 : Cunha, Di Ianni, Bozza, Giovannini, Zagarella, Zelante, DAngelo, Pierini, Pitzurra, Falzetti, Carotti, Perruccio, Latgé, Rodrigues, Velardi, Aversa, Romani, Carvalho et al.: Dectin-1 Y238X polymorphism associates with susceptibility to invasive aspergillosis in hematopoietic transplantation through impairment of both recipient- and donor-dependent mechanisms of ... in Blood 2010 (PubMed)
    Show all 6 references for 4897736

  3. Mouse (Murine) Monoclonal CLEC7A Primary Antibody for FACS, IHC (fro) - ABIN181896 : Taylor, Brown, Reid, Willment, Martinez-Pomares, Gordon, Wong: The beta-glucan receptor, dectin-1, is predominantly expressed on the surface of cells of the monocyte/macrophage and neutrophil lineages. in Journal of immunology (Baltimore, Md. : 1950) 2002 (PubMed)
    Show all 4 references for 181896

  4. Mouse (Murine) Monoclonal CLEC7A Primary Antibody for FACS - ABIN320108 : Brown, Taylor, Reid, Willment, Williams, Martinez-Pomares, Wong, Gordon: Dectin-1 is a major beta-glucan receptor on macrophages. in The Journal of experimental medicine 2002 (PubMed)
    Show all 4 references for 320108

  5. Mouse (Murine) Monoclonal CLEC7A Primary Antibody for FACS - ABIN4304746 : : Correction: A chitin-like component on sclerotic cells of fonsecaea pedrosoi inhibits dectin-1-mediated murine Th17 development by masking β-glucans. in PLoS ONE 2015 (PubMed)
    Show all 2 references for 4304746

  6. Mouse (Murine) Monoclonal CLEC7A Primary Antibody for FACS - ABIN181894 : Underhill, Rossnagle, Lowell, Simmons: Dectin-1 activates Syk tyrosine kinase in a dynamic subset of macrophages for reactive oxygen production. in Blood 2005 (PubMed)
    Show all 2 references for 181894

  7. Human Monoclonal CLEC7A Primary Antibody for FACS - ABIN4897732 : Sindrilaru, Peters, Wieschalka, Baican, Baican, Peter, Hainzl, Schatz, Qi, Schlecht, Weiss, Wlaschek, Sunderkötter, Scharffetter-Kochanek: An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice. in The Journal of clinical investigation 2011 (PubMed)

  8. Human Polyclonal CLEC7A Primary Antibody for WB - ABIN4304728 : Cohen-Kedar, Baram, Elad, Brazowski, Guzner-Gur, Dotan: Human intestinal epithelial cells respond to β-glucans via Dectin-1 and Syk. in European journal of immunology 2014 (PubMed)

  9. Mouse (Murine) Monoclonal CLEC7A Primary Antibody for FACS - ABIN4897760 : Xu, Huo, Gunawan, Su, Lam: Activated dectin-1 localizes to lipid raft microdomains for signaling and activation of phagocytosis and cytokine production in dendritic cells. in The Journal of biological chemistry 2009 (PubMed)

更多抗CLEC7A的相互作用对抗体

Pig (Porcine) C-Type Lectin Domain Family 7, Member A (CLEC7A) interaction partners

  1. These results suggest that functionally neutral polymorphisms in dectin-1 are widespread in pig populations

  2. recognition of beta-glucans appeared cell type-specific as both dectin-1 and CR3 (显示 ITGAM 抗体) are involved in the beta-glucan-mediated responses in pig macrophages.

Mouse (Murine) C-Type Lectin Domain Family 7, Member A (CLEC7A) interaction partners

  1. this study shows the critical role of Dectin-1 for inflammasome activation, restriction of parasite replication in macrophages, and mouse resistance to Leishmania amazonensis infection in vivo

  2. results demonstrate that Dectin-1-triggered Card9 (显示 CARD9 抗体) signaling but not inflammasome activation can potently cross-prime Ag-specific cytotoxic T-cells, suggesting that this pathway would be a candidate for immunotherapy and vaccine development

  3. Dectin 1 is highly expressed on macrophages in pancreatic ductal adenocarcinoma (PDA). Clec7a deletion is protective against PDA, however Clec7a does not have direct protumorigenic effects on transformed pancreatic ductal epithelial cells.

  4. Dectin-1 does not play a major role in in phagocytosis and innate defense by phagocytes against Cryptococcus neoformans spores.

  5. these results suggest that Dectin-1 expressed on CD11b (显示 ITGAM 抗体)(+) dendritic cells (DCs) senses some molecule(s) in house dust mite (HDM (显示 HDAC3 抗体)) extract and plays a critical role in the induction of HDM (显示 HDAC3 抗体)-induced allergic airway inflammation by inducing the expression of chemokine/chemokine (显示 CCL1 抗体) receptors in DCs.

  6. The sum of the data suggests that in contrast to IgG-based immune complexes boosting immune reactivity of antigen-presenting cells, secretory IgA produced during an ongoing immune response can, in addition to its known function of immune exclusion, modulate mucosal dendritic cell conditioning via specific interaction with Dectin-1 and SIGNR3.

  7. data suggest that the C-Type lectin receptor (显示 CLEC4D 抗体) Dectin-1 is a major pattern recognition receptor that orchestrates miR155 upregulation in a Syk (显示 SYK 抗体)-dependent manner; results suggest that PRR (显示 PVRL1 抗体)-mediating signaling events are key drivers of miRNA-mediated gene regulation during fungal pathogenesis

  8. results strongly suggest that Ae2 (显示 SLC4A2 抗体) is a critical factor in the innate response to C. albicans. This study represents an important contribution to a better understanding of how Dectin-1 expression and fungal clearance is regulated.

  9. this study shows that in vitro, cytokine production by bone marrow-derived dendritic cells is dependent on dectin-1; in vivo, its deficiency compromises fungal clearance

  10. SCIMP (显示 SCIMP 抗体) is strongly phosphorylated after Dectin-1 stimulation and that it participates in signal transduction downstream of this important pattern recognition receptor.

Human C-Type Lectin Domain Family 7, Member A (CLEC7A) interaction partners

  1. Unique cytokine secretion and varying expression levels of n Dectin-1 isoforms on monocyte-derived cells may indicate distinct isoform usage as a cell type-specific mechanism of regulating anti-fungal immunity.

  2. Dectin 1 is highly expressed on macrophages in pancreatic ductal adenocarcinoma.

  3. Dectin-1-mediated activation of the Syk (显示 SYK 抗体), MAPKs, PI3K (显示 PIK3CA 抗体) and NF-kappaB (显示 NFKB1 抗体) signaling pathways contributes to F. proliferatum-stimulated CXCL-8 (显示 IL8 抗体) release from BEAS-2B cells and provides an important basis for developing novel therapeutic strategies in clinical allergy.

  4. this study shows that curdlan inhibits tumor growth via activating dendritic cells through dectin-1 signaling

  5. Dectin-1 is essential for efficient immune response against Mycobacteria.

  6. dectin-1 has a role in glycyrrhetinic acid inhibition of contact hypersensitivity induced by trichophytin

  7. study represents the first analysis demonstrating that harbouring polymorphisms of Dectin-1 (rs7309123) or TLR2 (显示 TLR2 抗体) (rs5743708) represents an independent risk factor of developing IFD in patients with AML (显示 RUNX1 抗体) undergoing induction chemotherapy.

  8. TREM-1 (显示 TREM1 抗体) and Dectin-1 function concurrently in the corneal innate immune response by regulating inflammatory cytokine expression in fungal keratitis.

  9. Our data suggest that the genetic diversity of CLEC7A gene influences the autism spectrum disorders (ASD (显示 ARSD 抗体)) phenotype by behaving as a disease specifier and imply that the genetic control of innate immune response could determine the ASD (显示 ARSD 抗体) phenotype.

  10. The result of this study suggests that there is no correlation between Dectin-1 Y238X Gene polymorphism and RVVC.

Cow (Bovine) C-Type Lectin Domain Family 7, Member A (CLEC7A) interaction partners

  1. CLEC7a genetic variant c.589A>G was significantly associated (p = 0.008) with Mycobacterium avium ssp. paratuberculosis infection in Holsteins cattle.

CLEC7A 抗原简介

Antigen Summary

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.

Alternative names and synonyms associated with CLEC7A

  • C-type lectin domain family 7, member A (CLEC7A) 抗体
  • C-type lectin domain family 7, member a (Clec7a) 抗体
  • C-type lectin domain family 7, member A (Clec7a) 抗体
  • dendritic cell-associated C-type lectin 1 (LOC100339146) 抗体
  • beta-GR 抗体
  • BGR 抗体
  • CANDF4 抗体
  • CLEC7A 抗体
  • Clec7b 抗体
  • CLECSF12 抗体
  • DECTIN1 抗体
  • RGD1565140 抗体

Protein level used designations for CLEC7A

dendritic cell-associated C-type lectin 1 , C-type lectin domain family 7, member A , C-type lectin domain family 7 member A , dectin 1 , C-type (calcium dependent, carbohydrate recognition domain) lectin, superfamily member 12 , C-type lectin superfamily member 12 , DC-associated C-type lectin 1 , beta-glucan receptor , dectin-1 , C-type (calcium dependent, carbohydrate-recognition domain) lectin, superfamily member 12 , dendritic cell-associated C-type lectin-1 , lectin-like receptor 1

GENE ID SPECIES
473361 Pan troglodytes
611385 Canis lupus familiaris
678685 Ovis aries
100038025 Sus scrofa
56644 Mus musculus
64581 Homo sapiens
532865 Bos taurus
502902 Rattus norvegicus
574356 Macaca mulatta
100339146 Oryctolagus cuniculus
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