alpha-2-Macroglobulin (A2M) ELISA试剂盒

Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. 再加上,我们可以发alpha 2 Macroglobulin 抗体 (303)alpha 2 Macroglobulin 蛋白 (40)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
A2M 2 P01023
A2M 24153 P06238
A2M 232345 Q6GQT1
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1.25 1.25 Typical standard curve 96 Tests Log in to see 13至16个工作日
$1,026.67
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大鼠 3.125 ng/mL 3.13-800 ng/mL Typical standard curve 96 Tests Log in to see 13至16个工作日
$1,081.67
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小鼠 0.313-100 ng/mL 96 Tests Log in to see 2至3个工作日
$374.00
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Cow 0.078 0.312 Typical standard curve 96 Tests Log in to see 15至18个工作日
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小鼠 1.51 ng/mL 3.70-300 ng/mL 96 Tests Log in to see 13至16个工作日
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27.3 ng/mL 27.3-7000 ng/mL   96 Tests Log in to see 13至16个工作日
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5 ng/mL 12.3-3000 ng/mL   96 Tests Log in to see 3至4个工作日
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Pig 46.875 ng/mL 78.125-5000 ng/mL   96 Tests Log in to see 12至14个工作日
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大鼠 5.9 ng/mL 12.5 ng/mL - 800 ng/mL   96 Tests Log in to see 8至12个工作日
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0.469 ng/mL 0.781-50 ng/mL   96 Tests Log in to see 12至14个工作日
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引用最多的alpha 2 Macroglobulin ELISA试剂盒

  1. Human alpha 2 Macroglobulin ELISA Kit for Competition ELISA - ABIN2683306 : Pineda-Salgado, Craig, Blank, Kessler: Expression of Panza, an alpha2-macroglobulin, in a restricted dorsal domain of the primitive gut in Xenopus laevis. in Gene expression patterns : GEP 2005 (PubMed)
    Show all 5 Pubmed References

  2. Human alpha 2 Macroglobulin ELISA Kit for Sandwich ELISA - ABIN1874321 : Lee, Cho, Kim, Kang, Yoo, Chang, Ko, Kim: Semi-quantitative measurement of a specific glycoform using a DNA-tagged antibody and lectin affinity chromatography for glyco-biomarker development. in Molecular & cellular proteomics : MCP 2015 (PubMed)
    Show all 2 Pubmed References

  3. Mouse (Murine) alpha 2 Macroglobulin ELISA Kit for Sandwich ELISA - ABIN2683308 : Jensen, Humle Jørgensen, Datta, Sørensen: Significantly increased fractions of transformed to total alpha2-macroglobulin concentrations in plasma from patients with multiple sclerosis. in Biochimica et biophysica acta 2004 (PubMed)
    Show all 2 Pubmed References

  4. Human alpha 2 Macroglobulin ELISA Kit for Sandwich ELISA - ABIN2683305 : Tasnim, Zink: Cross talk between primary human renal tubular cells and endothelial cells in cocultures. in American journal of physiology. Renal physiology 2012 (PubMed)
    Show all 4 Pubmed References

  5. Human alpha 2 Macroglobulin ELISA Kit for Competition ELISA - ABIN366856 : Xu, Zhang, Luo, Zhou, Wang, Fang, Li, Mu, Zhang, Zhang, Xie: Comparative proteomic analysis of plasma from major depressive patients: identification of proteins associated with lipid metabolism and immunoregulation. in The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2012 (PubMed)

适于 alpha 2 Macroglobulin 相互作用对的更多 ELISA 试剂盒

Human alpha-2-Macroglobulin (A2M) interaction partners

  1. Proteomics study showed a strong association of FN1, A2M, C4BPA and CFB in molecular subtypes of breast cancer, in which, C4BPA and A2M demonstrated a potent signature in blood plasma and tissue samples of Luminal-B (LB) and Triple-negative (TN)subtypes in BC patients, respectively.

  2. BBB (显示 ALMS1 ELISA试剂盒) disruption is present in ACS (显示 PLA2G15 ELISA试剂盒), and elevated levels of IL-6 (显示 IL6 ELISA试剂盒) and C3 in CSF (显示 CSF2 ELISA试剂盒) in diffuse NPSLE

  3. Case Reports: inflammatory myofibroblastic tumors of the lung containing a chimeric A2M-ALK (显示 ALK ELISA试剂盒) gene categorized as a specific type of inflammatory myofibroblastic tumor that develops exclusively in neonates and infants.

  4. The plasma level of alpha2M was found positively correlated, while HCII (显示 SERPIND1 ELISA试剂盒) level was negatively correlated with higher vulnerability of carotid plaques. Both proteins were efficient in differentiating stable and vulnerable carotid plaques. These provide potential new targets for the research of carotid plaque vulnerability. Plasma alpha2M and HCII (显示 SERPIND1 ELISA试剂盒) may be potential biomarkers for evaluation of the vulnerability of carotid ...

  5. Stabilizers during pasteurization improved alpha-2-macroglobulin (alpha2-M) activity by more than 300% points compared with the unstabilized control.

  6. Data show that low that low globulin (GLB (显示 DCXR ELISA试剂盒)) levels were significantly associated with favorable survival, and low ALB (显示 ALB ELISA试剂盒) levels were associated with a significantly worse survival .

  7. This work demonstrates that alpha2M*/CS-GRP78 (显示 HSPA5 ELISA试剂盒) acts as an upstream regulator of the PDK1 (显示 PDK1 ELISA试剂盒)/PLK1 (显示 PLK1 ELISA试剂盒) signaling axis to modulate c-MYC (显示 MYC ELISA试剂盒) transcription and its target genes, suggesting a therapeutic strategy for targeting c-MYC (显示 MYC ELISA试剂盒)-associated malignant progression.

  8. Meta-analysis. Our data indicate that the rs669 (A/G) polymorphisms in A2M gene are associated with increased risk in Parkinson disease.

  9. These data demonstrate that alpha2M* and LRP1 (显示 LRP1 ELISA试剂盒) modulate the BKCachannel in human myometrium and that BKCaand its immunomodulatory interacting partners regulate Ca(2 (显示 CA2 ELISA试剂盒)+)dynamics in hMSMCs during pregnancy.

  10. we identify a single serum factor, alpha2-macroglobulin (alpha2M), which is both required and sufficient for rosetting mediated by the parasite protein P. falciparum erythrocyte membrane protein 1 protein HB3VAR06 and some other rosette-mediating PfEMP1 proteins

Mouse (Murine) alpha-2-Macroglobulin (A2M) interaction partners

  1. A model is proposed that suggests that unlike proteases, which are irreversibly bound to activated alpha2M, hepcidin (显示 HAMP ELISA试剂盒) remains labile and available to down-regulate Fpn1 (显示 SLC40A1 ELISA试剂盒).

  2. Data show that MAA-A2M adduct formation abrogated the binding of A2M bait region with TGF-beta1, trypsin, and elastase.

  3. MMP9 (显示 MMP9 ELISA试剂盒) production promoted by the alpha(2)M*/LRP1 (显示 LRP1 ELISA试剂盒) interaction required the activation of both MAPK (显示 MAPK1 ELISA试剂盒)-ERK1/2 (显示 MAPK1/3 ELISA试剂盒) and NF-kappaB (显示 NFKB1 ELISA试剂盒) signaling pathways.

  4. Alpha2 macroglobulin requires cyclic amp (显示 TMPRSS5 ELISA试剂盒) and signal transduction for cell growth

  5. Increased Trypanosoma cruzi invasion and heart fibrosis associated with high transforming growth factor beta levels in mice deficient in alpha(2)-macroglobulin.

  6. the 4622-base pair cDNA encodes a protein of 1473 AA with >70% sequence identity and all typical domains of other A2M-family members in humans and rodents

  7. Data describe the role of the PI3-kinase (显示 PIK3CA ELISA试剂盒)/PDK (显示 PDK2 ELISA试剂盒)/Akt (显示 AKT1 ELISA试剂盒)/p70s6k (显示 RPS6KB1 ELISA试剂盒) signaling cascade in alpha 2-macroglobulin-induced cellular proliferation and the role of CREB (显示 CREB1 ELISA试剂盒) in these events.

  8. review the A2M gene families of mice and humans, the predicted structural relationships between A2M and its pregnancy induced forms and the postulated roles for this gene family in normal pregnancy.

  9. the inhibition of proteases on the surface of microorganisms by an ancestral alpha2M-like thiol ester protein may generate "arrays" of oligomannose glycans to which MBL or other lectins can bind

  10. PDGF (显示 PDGFA ELISA试剂盒)-BB and TGF-beta1 (显示 TGFB1 ELISA试剂盒) binding to intact alpha2M is specific, involving a defined region of the alpha2M subunit

Pig (Porcine) alpha-2-Macroglobulin (A2M) interaction partners

  1. Data suggest that alpha(2)-macroglobulin from serum could significantly compensate for the impaired cumulus expansion of oocytes matured in serum.

Cow (Bovine) alpha-2-Macroglobulin (A2M) interaction partners

  1. Mutations in the promoter region and the 3'-untranslated region of the A2M gene are involved in the mastitis susceptibility in dairy cows.

  2. We report here for the first time the direct isolation of Spp24 (显示 SPP2 ELISA试剂盒) covalently bound to alpha2-macroglobulins as a core complex (Spp24 (显示 SPP2 ELISA试剂盒)-alpha2M) from bovine calf serum.

  3. Exon 29 c.3535A>T in the alpha-2-macroglobulin gene causing aberrant splice variants is associated with mastitis.

  4. These results suggest the possible involvement of cathepsin E (显示 CTSE ELISA试剂盒) in disruption of the structural and functional integrity of alpha 2-macroglobulin in the endolysosome system.

  5. Alpha2-macroglobulin is a substrate and an endogenous inhibitor for ADAMTS-4 (显示 ADAMTS4 ELISA试剂盒) and ADAMTS-5 (显示 ADAMTS5 ELISA试剂盒)

  6. Amounts of alpha(2)-M receptor in granulosa cells were strongly inversely associated with concentrations of estradiol in dominant and subordinate follicles.

alpha 2 Macroglobulin (A2M) 抗原简介

Antigen Summary

Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits.

Gene names and symbols associated with A2M

  • alpha-2-macroglobulin (A2M) 抗体
  • alpha-2-macroglobulin (A2m) 抗体
  • alpha-2-macroglobulin (LOC477699) 抗体
  • pregnancy-zone protein L homeolog (pzp.L) 抗体
  • alpha-2-macroglobulin (AZL_c00450) 抗体
  • ovostatin-like (LOC100224071) 抗体
  • alpha-2-macroglobulin (LOC100349077) 抗体
  • ovostatin (OVST) 抗体
  • alpha-2-macroglobulin (a2m) 抗体
  • alpha-2-macroglobulin (LOC100061656) 抗体
  • alpha-2-macroglobulin (LOC100090399) 抗体
  • alpha-2-macroglobulin S homeolog (a2m.S) 抗体
  • alpha-2-macroglobulin (LOC100469973) 抗体
  • alpha-2-macroglobulin (LOC100595735) 抗体
  • pregnancy zone protein (PZP) 抗体
  • alpha-2-macroglobulin (LOC100353095) 抗体
  • alpha-2-macroglobulin (LOC101122940) 抗体
  • alpha-2-macroglobulin (LOC101801552) 抗体
  • alpha-2-macroglobulin-like (LOC100911545) 抗体
  • A2M 抗体
  • A2m1 抗体
  • A2maa 抗体
  • A2MAC1 抗体
  • a2mb 抗体
  • A2MD 抗体
  • A2mp 抗体
  • Alpha-2-M 抗体
  • cpamd5 抗体
  • endod 抗体
  • endodermin 抗体
  • fwp007 抗体
  • LOC733429 抗体
  • LOC100224071 抗体
  • Mam 抗体
  • s863-7 抗体

Protein level used designations for A2M

C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5 , alpha-2-M , alpha-2-macroglobulin-P , alpha-2-macroglobulin , alpha-2-macroglobulin-like , ovomacroglobulin, ovostatin , alpha 2m , endodermin , Alpha2-macroglobulin , alpha-2-macroglobulin b , pregnancy zone protein

GENE ID SPECIES
2 Homo sapiens
24153 Rattus norvegicus
232345 Mus musculus
403166 Sus scrofa
418251 Gallus gallus
465372 Pan troglodytes
477699 Canis lupus familiaris
513856 Bos taurus
716834 Macaca mulatta
733429 Xenopus laevis
8794592 Azospirillum sp. B510
100173946 Pongo abelii
100224071 Taeniopygia guttata
100349077 Oryctolagus cuniculus
100390764 Callithrix jacchus
396151 Gallus gallus
619586 Xenopus (Silurana) tropicalis
100061656 Equus caballus
100090399 Ornithorhynchus anatinus
100158443 Xenopus laevis
100469973 Ailuropoda melanoleuca
100595735 Nomascus leucogenys
100153288 Sus scrofa
100353095 Oryctolagus cuniculus
101122940 Ovis aries
101801552 Anas platyrhynchos
100911545 Rattus norvegicus
101794357 Anas platyrhynchos
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