anti-LIM and SH3 Protein 1 (LASP1) 抗体

LASP1 encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. 再加上,我们可以发LASP1 蛋白 (16)LASP1 试剂盒 (11)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
LASP1 3927 Q14847
LASP1 16796 Q61792
LASP1 29278 Q99MZ8

antibodies-online.cn销售最多的anti-LASP1 抗体

Showing 10 out of 112 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB WB Suggested Anti-LASP1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:2500 Positive Control: MCF7 cell lysate 100 μL Log in to see 24至29个工作日
Cow 非结合性 IHC, WB Rabbit Anti-LASP1 Antibody Catalog Number: ARP54798_P050 Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue Observed Staining: Cytoplasmic Primary Antibody Concentration: N/A Other Working Concentrations: 1:600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec WB Suggested Anti-LASP1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:12500 Positive Control: HepG2 cell lysate LASP1 is supported by BioGPS gene expression data to be expressed in HepG2 100 μL Log in to see 24至29个工作日
非结合性 EIA, WB Western blot analysis of LASP1 Antibody (Center) in A549 cell line lysates (35ug/lane). This demonstrates the LASP1 antibody detected the LASP1 protein (arrow). 0.4 mL Log in to see 29至35个工作日
山羊 非结合性 ELISA, WB ABIN184658 staining (0.1µg/ml) of Human Brain (Cerebellum) extracts (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Log in to see 24至29个工作日
小鼠 非结合性 WB Western Blot analysis of LASP1 expression in transfected 293T cell line by LASP1 monoclonal antibody (M05), clone 4F5. Lane 1: LASP1 transfected lysate(29.7 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 11至15个工作日
非结合性 ICC, IHC (p), WB Anti-LASP1 antibody,  Western blotting Lane 1: HELA Cell Lysate Lane 2: MCF-7 Cell Lysate Anti-LASP1 antibody, ICC ICC: A549 Cell 100 μg Log in to see 26至32个工作日
山羊 非结合性 ELISA, IHC (p), WB ABIN262290 (0.1µg/ml) staining of Human Kidney lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 25至31个工作日
山羊 非结合性 WB   0.1 mg Log in to see 30至37个工作日
山羊 非结合性 WB   0.1 mg Log in to see 28至34个工作日
非结合性 ICC, IF, IHC, IHC (p), WB Western Blot: LASP1 Antibody [NBP1-82844] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4 Immunohistochemistry-Paraffin: LASP1 Antibody [NBP1-82844] - Staining of human tonsil shows distinct cytoplasmic positivity in cells in reaction center. 0.1 mL Log in to see 28至35个工作日

通过反应活性、应用领域、克隆类型和共轭标记 LASP1 抗体

特性 应用范围 宿主 克隆类型 标记
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Mouse (Murine)

Rat (Rattus)

引用最多的anti-LASP1 抗体

  1. Human Monoclonal LASP1 Primary Antibody for WB - ABIN396389 : Frietsch, Grunewald, Jasper, Kammerer, Herterich, Kapp, Honig, Butt: Nuclear localisation of LASP-1 correlates with poor long-term survival in female breast cancer. in British journal of cancer 2010 (PubMed)
    Show all 5 references for 396389

  2. Human Polyclonal LASP1 Primary Antibody for EIA, WB - ABIN953141 : Traenka, Remke, Korshunov, Bender, Hielscher, Northcott, Witt, Ryzhova, Felsberg, Benner, Riester, Scheurlen, Grunewald, von Deimling, Kulozik, Reifenberger, Taylor, Lichter, Butt, Pfister: Role of LIM and SH3 protein 1 (LASP1) in the metastatic dissemination of medulloblastoma. in Cancer research 2010 (PubMed)
    Show all 4 references for 953141

  3. Human Polyclonal LASP1 Primary Antibody for ELISA, IHC (p) - ABIN262290 : Grunewald, Kammerer, Schulze, Schindler, Honig, Zimmer, Butt: Silencing of LASP-1 influences zyxin localization, inhibits proliferation and reduces migration in breast cancer cells. in Experimental cell research 2006 (PubMed)

  4. Human Polyclonal LASP1 Primary Antibody for ICC, IF - ABIN4330347 : Ngan, Northey, Brown, Ursini-Siegel, Siegel: A complex containing LPP and α-actinin mediates TGFβ-induced migration and invasion of ErbB2-expressing breast cancer cells. in Journal of cell science 2013 (PubMed)

  5. Cow (Bovine) Polyclonal LASP1 Primary Antibody for IHC, WB - ABIN2785891 : Stone, Merriman, Cantor, Geschwind, Nelson: High density SNP association study of a major autism linkage region on chromosome 17. in Human molecular genetics 2007 (PubMed)

  6. Human Polyclonal LASP1 Primary Antibody for ELISA, WB - ABIN184658 : Schreiber, Moog-Lutz, Régnier, Chenard, Boeuf, Vonesch, Tomasetto, Rio: Lasp-1, a novel type of actin-binding protein accumulating in cell membrane extensions. in Molecular medicine (Cambridge, Mass.) 1999 (PubMed)


Human LIM and SH3 Protein 1 (LASP1) interaction partners

  1. The correlation between LIM (显示 PDLIM5 抗体) and SH3 domain-containing protein (显示 PEX13 抗体) expression levels in cancer and the poor outcome and metastatic behavior of tumors denotes the clinical significance of this protein and hints its potential value as a new cancer prognostic or even diagnostic biomarker

  2. LASP-1 contributes to the formation and progression of prostate cancer through a NF-kappaappa B pathway.

  3. LASP-1 may essentially involve in the metastasis and growth of CCA (显示 FBN2 抗体) and clinical significance of LASP-1 may reside in function as a biomarker to predict prognosis and as a promising therapeutic strategy for CCA (显示 FBN2 抗体) patients by the inhibition of LASP-1 expression

  4. It is a target gene of miR-1.

  5. LASP-1 associated with UHRF1 (显示 UHRF1 抗体), G9a (显示 EHMT2 抗体), Snail1 (显示 SNAI1 抗体) and di- and tri (显示 VANGL2 抗体)-methylated histoneH3 in a CXCL12 (显示 CXCL12 抗体)-dependent manner based on immunoprecipitation and proximity ligation assays

  6. LASP-1 induces proliferation, metastasis and cell cycle arrest at the G2/M phase in gallbladder cancer by down-regulating S100P (显示 S100P 抗体) via the PI3K (显示 PIK3CA 抗体)/AKT (显示 AKT1 抗体) pathway.

  7. LASP-1, mediated by miR (显示 MLXIP 抗体)-203, has crucial functions in the proliferation, migration and invasion of human non-small cell lung cancer

  8. Detecting an affection of migratory processes after LASP-1 silencing, we propose that LASP-1 could impact on metastasis of CC [choriocarcinoma]cells.

  9. Results identified LASP1 as a hitherto unknown protein in melanocytes and as novel partner of dynamin (显示 DNM1 抗体) in the physiological process of membrane constriction and melanosome vesicle release.

  10. Our results suggest that LASP-1 mRNA overexpression may be mainly implicated in female hepatocellular carcinoma (HCC (显示 FAM126A 抗体)) and cirrhotic HCCs (显示 HCCS 抗体); and that LASP1 may play its role with vimentin (显示 VIM 抗体) in HCC (显示 FAM126A 抗体) cells.

Mouse (Murine) LIM and SH3 Protein 1 (LASP1) interaction partners

  1. Results defined LASP1 as a direct target gene for HIF1alpha (显示 HIF1A 抗体) upregulation that is critical for metastatic progression of PDAC.

  2. Data show that MEFs derived from Lasp1(-/-) mice migrated more rapidly in vitro.

  3. LIM-nebulette (显示 NEBL 抗体), Lasp-1, and zyxin (显示 ZYX 抗体) may play an important role in the organization of focal adhesions

  4. Lasp-1 is a dynamic focal adhesion protein necessary for cell migration and survival in response to growth factors and ECM (显示 MMRN1 抗体) proteins.

  5. Data suggest that there are no functional differences between human and mouse LASP-1.

  6. The role of Lasp1 in the regulation of hydrochloride secretion in vivo was studied in a murine model with a targeted disruption of the Lasp-1 gene.

  7. role of Lasp1 in chondrocyte differentiation during cartilage to bone transition

LASP1 抗原简介


This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer.

Gene names and symbols associated with LASP1

  • LIM and SH3 domain protein 1 (lasp1) 抗体
  • LIM and SH3 protein 1 (lasp1) 抗体
  • LIM and SH3 protein 1 (LASP1) 抗体
  • lasp1 protein (lasp1) 抗体
  • LIM and SH3 protein 1 (Lasp1) 抗体
  • AA408629 抗体
  • Def-4 抗体
  • fb92f05 抗体
  • lasp-1 抗体
  • LASP1 抗体
  • MGC53336 抗体
  • MGC89667 抗体
  • mln50 抗体
  • SH3P6 抗体
  • Tg(Col1a1-lacZ)1Ngma 抗体
  • wu:fb92f05 抗体
  • zgc:77542 抗体

Protein level used designations for LASP1

LIM and SH3 domain protein 1 , LIM and SH3 protein 1 , lasp1 protein , metastatic lymph node gene 50 protein , LASP-1 , MLN 50 , Tg(11Col1a1)NG , 40 kDa phosphoprotein , phosphoprotein Lasp-1 , pp40

100195513 Salmo salar
380354 Xenopus laevis
454620 Pan troglodytes
493322 Xenopus (Silurana) tropicalis
694950 Macaca mulatta
420002 Gallus gallus
3927 Homo sapiens
16796 Mus musculus
29278 Rattus norvegicus
608624 Canis lupus familiaris
323216 Danio rerio
495167 Xenopus laevis
532851 Bos taurus
100009568 Oryctolagus cuniculus
100173670 Pongo abelii
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