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LASP1 encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. 再加上，我们可以发LASP1 蛋白 (13) 和 LASP1 试剂盒 (12)和数多这个蛋白质的别的产品。
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Human Polyclonal LASP1 Primary Antibody for ELISA, IHC (p) - ABIN262290
Grunewald, Kammerer, Schulze, Schindler, Honig, Zimmer, Butt: Silencing of LASP-1 influences zyxin localization, inhibits proliferation and reduces migration in breast cancer cells. in Experimental cell research 2006
Cow (Bovine) Polyclonal LASP1 Primary Antibody for IHC, WB - ABIN2785891
Stone, Merriman, Cantor, Geschwind, Nelson: High density SNP association study of a major autism linkage region on chromosome 17. in Human molecular genetics 2007
Human Polyclonal LASP1 Primary Antibody for ELISA, WB - ABIN4330346
Schreiber, Moog-Lutz, Régnier, Chenard, Boeuf, Vonesch, Tomasetto, Rio: Lasp-1, a novel type of actin-binding protein accumulating in cell membrane extensions. in Molecular medicine (Cambridge, Mass.) 1999
Human Polyclonal LASP1 Primary Antibody for ICC, IF - ABIN4330347
Ngan, Northey, Brown, Ursini-Siegel, Siegel: A complex containing LPP and α-actinin mediates TGFβ-induced migration and invasion of ErbB2-expressing breast cancer cells. in Journal of cell science 2013
miR (显示 MLXIP 抗体)-218 contributes to PE by targeting LASP1 to inhibit trophoblast invasion
The correlation between LIM (显示 PDLIM5 抗体) and SH3 domain-containing protein (显示 PEX13 抗体) expression levels in cancer and the poor outcome and metastatic behavior of tumors denotes the clinical significance of this protein and hints its potential value as a new cancer prognostic or even diagnostic biomarker
LASP-1 contributes to the formation and progression of prostate cancer through a NF-kappaappa B pathway.
LASP-1 may essentially involve in the metastasis and growth of CCA (显示 FBN2 抗体) and clinical significance of LASP-1 may reside in function as a biomarker to predict prognosis and as a promising therapeutic strategy for CCA (显示 FBN2 抗体) patients by the inhibition of LASP-1 expression
It is a target gene of miR-1.
LASP-1 associated with UHRF1 (显示 UHRF1 抗体), G9a (显示 EHMT2 抗体), Snail1 (显示 SNAI1 抗体) and di- and tri (显示 VANGL2 抗体)-methylated histoneH3 in a CXCL12 (显示 CXCL12 抗体)-dependent manner based on immunoprecipitation and proximity ligation assays
LASP-1 induces proliferation, metastasis and cell cycle arrest at the G2/M phase in gallbladder cancer by down-regulating S100P (显示 S100P 抗体) via the PI3K (显示 PIK3CA 抗体)/AKT (显示 AKT1 抗体) pathway.
LASP-1, mediated by miR (显示 MLXIP 抗体)-203, has crucial functions in the proliferation, migration and invasion of human non-small cell lung cancer
Detecting an affection of migratory processes after LASP-1 silencing, we propose that LASP-1 could impact on metastasis of CC [choriocarcinoma]cells.
Results identified LASP1 as a hitherto unknown protein in melanocytes and as novel partner of dynamin (显示 DNM1 抗体) in the physiological process of membrane constriction and melanosome vesicle release.
Results defined LASP1 as a direct target gene for HIF1alpha (显示 HIF1A 抗体) upregulation that is critical for metastatic progression of PDAC.
Data show that MEFs derived from Lasp1(-/-) mice migrated more rapidly in vitro.
LIM-nebulette (显示 NEBL 抗体), Lasp-1, and zyxin (显示 ZYX 抗体) may play an important role in the organization of focal adhesions
Lasp-1 is a dynamic focal adhesion protein necessary for cell migration and survival in response to growth factors and ECM (显示 MMRN1 抗体) proteins.
Data suggest that there are no functional differences between human and mouse LASP-1.
The role of Lasp1 in the regulation of hydrochloride secretion in vivo was studied in a murine model with a targeted disruption of the Lasp-1 gene.
role of Lasp1 in chondrocyte differentiation during cartilage to bone transition
This gene encodes a member of a subfamily of LIM proteins, characterized by a LIM motif and a domain of Src homology region 3, and also a member of the nebulin family of actin-binding proteins. The encoded protein is a cAMP and cGMP dependent signaling protein and binds to the actin cytoskeleton at extensions of the cell membrane. The encoded protein has been linked to metastatic breast cancer, hematopoetic tumors such as B-cell lymphomas, and colorectal cancer.
LIM and SH3 domain protein 1
, LIM and SH3 protein 1
, lasp1 protein
, metastatic lymph node gene 50 protein
, MLN 50
, 40 kDa phosphoprotein
, phosphoprotein Lasp-1