Fyn-Related Kinase 蛋白 (FRK)

The protein encoded by FRK belongs to the TYR family of protein kinases. 再加上,我们可以发FRK 抗体 (161)FRK 试剂盒 (5)和数多这个蛋白质的别的产品。

列出全部蛋白 基因 基因ID UniProt
大鼠 FRK FRK 25468 P63142
FRK 2444 P42685
FRK 14302 Q922K9

antibodies-online.cn销售最多的FRK 蛋白

Showing 9 out of 12 products:

产品编号 Origin 资源 标记 图像 规格 供应商 交付 价格 详细
HOST_Baculovirus infected Insect Cells 非结合性 5 μg Log in to see 24至29个工作日
Insect Cells His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 78至82个工作日
Insect Cells 小鼠 His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 78至82个工作日
小麦胚 GST tag 10 μg Log in to see 29至34个工作日
Insect Cells His-GST   100 μg Log in to see 29至34个工作日
HOST_Baculovirus infected Insect Cells GST tag   5 μg Log in to see 28至34个工作日
Insect Cells GST tag   10 μg Log in to see 25至30个工作日
大肠杆菌(E. Coli) T7 tag,His tag   100 μg Log in to see 9至12个工作日
HOST_Sf-9 cells 非结合性   5 μg Log in to see 24至29个工作日

FRK 蛋白 by Origin and Source

Origin 在表达 标记
Human , , , ,
, , ,
Mouse (Murine)

更多Fyn-Related Kinase (FRK)互动伙伴

Human Fyn-Related Kinase (FRK) interaction partners

  1. our results present the first evidence that site-specific promoter methylation contributes to the repression of FRK more so in basal B breast cancers.

  2. Loss of FRK protein may be implicated into the tumorigenesis and cell motility/invasiveness of human cervical cancer.

  3. antagomir-1290 significantly inhibited the proliferation, clonogenicity, invasion, and migration of CD133(+) cells by targeting fyn (显示 FYN 蛋白)-related Src (显示 SRC 蛋白) family tyrosine kinase (显示 TXK 蛋白).

  4. our results demonstrate a combined mechanism for the anti-proliferative effects of FRK by inhibiting cyclin D1 (显示 CCND1 蛋白) nucleus accumulation and pRb (显示 RB1 蛋白) phosphorylation in glioma cells.

  5. FRK over-expression promoted beta-catenin (显示 CTNNB1 蛋白) translocation to the plasma membrane, where it formed complex with N-cadherin (显示 CDH2 蛋白).

  6. exome sequencing identified recurrent somatic FRK mutations that induce constitutive kinase activity, STAT3 (显示 STAT3 蛋白) activation, and cell proliferation sensitive to Src (显示 SRC 蛋白) inhibitors

  7. Data indicaate that the Rak/Frk SH2 and SH3 domains collaborate to increase the Rak-EGFR (显示 EGFR 蛋白) interaction.

  8. The expression levels of FRK were significantly correlated with invasiveness in both Hep3B and HepG2 tumor cell lines.

  9. these results clearly indicate that FRK may play a protective role against the progression of glioma by suppressing cell migration and invasion

  10. Genetic variation near FRK/COL10A1 (显示 COL10A1 蛋白) and VEGFA (显示 VEGFA 蛋白) are associated with advanced age-related macular degeneration.

Mouse (Murine) Fyn-Related Kinase (FRK) interaction partners

  1. Characterization of mice deficient in the Src (显示 SRC 蛋白) family nonreceptor tyrosine kinase (显示 TYRO3 蛋白) Frk/rak. Decreases in the circulating levels of T3 but not T4 are reminiscent of euthyroid sick syndrome, a stress-associated clinical condition

  2. The tyrosine kinases Brk/PTK6/Sik (显示 PTK6 蛋白), Srm (显示 SRM 蛋白), Frk/Rak/Gtk/Iyk/Bsk (显示 EPHA5 蛋白), and Src42A/Dsrc41 have a low degree of sequence homology to other known kinases. The exon structure of these kinases, called the Brk (显示 PTK6 蛋白) family, is highly conserved and distinct.

  3. Experiments with Fyn (显示 FYN 蛋白)-deficient mice indicate that Fyn (显示 FYN 蛋白) genotype does not influence ethanol consumption, neither under basal conditions nor following a deprivation period or stress.

  4. These results show that FRK affects beta cell number during embryogenesis and early in life, but is probably redundant for beta cell number and function in adult animals under normal conditions.



The protein encoded by this gene belongs to the TYR family of protein kinases. This tyrosine kinase is a nuclear protein and may function during G1 and S phase of the cell cycle and suppress growth.

Gene names and symbols associated with Fyn-Related Kinase 蛋白 (FRK)

  • potassium voltage-gated channel, shaker-related subfamily, member 2 (Kcna2)
  • Fyn-related kinase (FRK)
  • fyn-related kinase (FRK)
  • fyn-related kinase (frk)
  • fyn-related kinase (Frk)
  • BK2 蛋白
  • BSK 蛋白
  • BSK/IYK 蛋白
  • C85044 蛋白
  • FRK 蛋白
  • GTK 蛋白
  • NGK1 蛋白
  • PTK5 蛋白
  • RAK 蛋白

Protein level used designations for Fyn-Related Kinase 蛋白 (FRK)

Potassium (K+) channel protein alpha 2, voltage dependent , RAK , RBK2 , RCK5 , potassium voltage gated channel shaker related subfamily member 2 , potassium voltage-gated channel subfamily A member 2 , voltage-gated potassium channel subunit Kv1.2 , hypothetical protein LOC583550 , fyn-related kinase , tyrosine-protein kinase FRK-like , PTK5 protein tyrosine kinase 5 , nuclear tyrosine protein kinase RAK , protein-tyrosine kinase 5 , tyrosine-protein kinase FRK , B-cell src-homology tyrosine kinase , beta-cell Src-homology tyrosine kinase , intestine tyrosine kinase , GASK , GTK , gastrointestinal-associated kinase , gastrointestinal-associated tyrosine kinase , src related tyrosine kinase

25468 Rattus norvegicus
583550 Strongylocentrotus purpuratus
481970 Canis lupus familiaris
462953 Pan troglodytes
716267 Macaca mulatta
100403046 Callithrix jacchus
100448548 Pongo abelii
100488362 Xenopus (Silurana) tropicalis
100540680 Meleagris gallopavo
100593495 Nomascus leucogenys
2444 Homo sapiens
421747 Gallus gallus
509227 Bos taurus
14302 Mus musculus
79209 Rattus norvegicus
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