Cystathionine-beta-Synthase (CBS) ELISA试剂盒

The protein encoded by CBS acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. 再加上,我们可以发Cystathionine-beta-Synthase 抗体 (108)Cystathionine-beta-Synthase 蛋白 (30)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
CBS 24250 P32232
CBS 12411 Q91WT9
CBS 875 P35520

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产品编号 适用 灵敏度 范围 图像 规格 供应商 交付 价格 详细
31.25 pg/mL 125-8000 pg/mL Typical standard curve 96 Tests Log in to see 7至10个工作日
¥3,994.38
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小鼠 0.059 ng/mL 0.156-10 ng/mL 96 Tests Log in to see 9至11个工作日
¥4,410.90
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大鼠 7.8 pg/mL 31.25-2000 pg/mL Typical standard curve 96 Tests Log in to see 7至10个工作日
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0.79 ng/mL 1.56-100 ng/mL   96 Tests Log in to see 24至29个工作日
¥6,140.16
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大鼠 15.6-1000 ng/mL   96 Tests Log in to see 24至29个工作日
¥6,140.16
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引用最多的Cystathionine-beta-Synthase ELISA试剂盒

  1. Human CBS ELISA Kit for Sandwich ELISA - ABIN456995 : Sun, Sun, Li, Pan, Xie, Wang, Zhang: Potential biomarkers predicting risk of pulmonary hypertension in congenital heart disease: the role of homocysteine and hydrogen sulfide. in Chinese medical journal 2014 (PubMed)

适于 Cystathionine-beta-Synthase 相互作用对的更多 ELISA 试剂盒

Chimpanzee Cystathionine-beta-Synthase (CBS) interaction partners

Mouse (Murine) Cystathionine-beta-Synthase (CBS) interaction partners

  1. showed that N-homocysteinylation of collagen in Cbs(-/-) mice impairs its cross-linking

  2. the findings of this study indicate that a deficiency in 3MST does not significantly affect endotoxemia, while a deficiency in CBS or CSE (显示 CTH ELISA试剂盒) slightly ameliorates the outcome of LPS (显示 TLR4 ELISA试剂盒)-induced endotoxemia in vivo.

  3. These data confirm a key role for the H2S-generating enzymes Cbs and Cth (显示 CTH ELISA试剂盒) in pulmonary vascular development and homeostasis and in lung alveolarization.

  4. genetic deficiency results in reduced Tet1 and Tet2 (显示 TET2 ELISA试剂盒) expression, which leads to hypermethylation of Foxp3 (显示 FOXP3 ELISA试剂盒), and impairment of Treg cell differentiation and immune homeostasis.

  5. Elevated homocytsteine levels in the CBS-/+ mouse skeletal muscles caused diminished anti-oxidant capacity and contributed to enhanced total protein as well as PGC-1alpha (显示 PPARGC1A ELISA试剂盒) specific nitrotyrosylation after ischemia.

  6. CBS disruption causes embryo retention and developmental delay in the mouse oviduct.

  7. CBS is present in adrenocortical cells and accounts for H2S generation in adrenal glands. CBS is critical for maintenance of mitochondrial function and glucocorticoid production in adrenal cortex.

  8. Elevating endogenous H2S via CBS over-expression in immortalized microglia not only reduced the expression of pro-inflammatory M1 genes, but also enhanced the anti-inflammatory M2 marker IL-10 (显示 IL10 ELISA试剂盒) production.

  9. Cbs protein expression is upregulated in brain cortex following traumatic brain injury.

  10. Brain of mice heterozygous for Cbs displays overexpression of DYR (显示 DHFR ELISA试剂盒) kinase and SAH (显示 ACSM3 ELISA试剂盒) hydrolase.

Human Cystathionine-beta-Synthase (CBS) interaction partners

  1. SNPs in CBS were not related to relevant changes in homocysteine levels in coronary artery disease patients or controls.

  2. The CBS rs2124459 was associated with a reduced risk of cleft palate in both French and Belgian populations. These results highlight the prominent involvement of the vitamin B6-dependent transsulfuration pathway of homocysteine in orofacial cleft risk and the interest for evaluating vitamin B6 status in further population studies.

  3. There is no ordinary conjunction between human CBS and severe sepsis/septic shock, but CBS genotypes are involved in disease susceptibility.

  4. Oligomeric status of human cystathionine beta-synthase modulates AdoMet (显示 MAT1A ELISA试剂盒) binding.

  5. Significant interactions were observed among the methylenetetrahydrofolate reductase (MTHFR (显示 MTHFR ELISA试剂盒); C677T; A1298C) and cystathionine-beta-synthase (CBS; T833C/844ins68, G919A) polymorphisms in the results for homocysteine (Hcy) levels, where heterozygous had higher values.

  6. results indicate that binding of SAM (显示 TTN ELISA试剂盒) to regulatory and stabilizing sites in CBS may have evolved to display an exquisite thermodynamic and structural specificity towards SAM (显示 TTN ELISA试剂盒) as well as the ability to transduce the allosteric signal responsible for CBS activation.

  7. CBS 844ins68 polymorphisms were not associated with Oral squamous cell carcinoma risk in southeastern Brazilians.

  8. This is the first mutational analysis of CBS done in a Filipino patient with classic homocystinuria who presented with a novel duplication mutation and a novel missense mutation.

  9. Two novel compound heterozygous mutations in the CBS gene, c.407T > C (p. L136P) and c.473C > T (p.A158V), were identified in the three patients of a Han Chinese family with homocystinuria

  10. SNP rs11203172 in the CBS gene is associated with a significantly decreased risk to develop early-onset preeclampsia.

Cow (Bovine) Cystathionine-beta-Synthase (CBS) interaction partners

  1. These findings indicate that greater synthesis of phosphatidylcholine (显示 SGMS1 ELISA试剂盒) and antioxidants contribute to the better performance and immuno-metabolic status in methionine-supplemented cows.

Cystathionine-beta-Synthase (CBS) 抗原简介

Antigen Summary

The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. Multiple alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with CBS

  • cystathionine-beta-synthase (cbs-a) 抗体
  • cystathionine-beta-synthase (cbs) 抗体
  • cystathionine beta-synthase (Cbs) 抗体
  • cystathionine-beta-synthase (CBS) 抗体
  • cystathionine beta-synthase (CNA06170) 抗体
  • cystathionine beta-synthase (Tb11.02.5400) 抗体
  • cystathionine beta-synthase CBS (cbs) 抗体
  • cystathionine beta-synthase (cbs) 抗体
  • cystathionine beta-synthase (cysB) 抗体
  • cystathionine beta synthase (Cbs) 抗体
  • cystathionine-beta-synthase (cbs-b) 抗体
  • cystathionine-beta-synthase b (cbsb) 抗体
  • AI047524 抗体
  • AI303044 抗体
  • cb442 抗体
  • cbs 抗体
  • DDBDRAFT_0189727 抗体
  • DDBDRAFT_0191292 抗体
  • DDB_0189727 抗体
  • DDB_0191292 抗体
  • GB12529 抗体
  • HIP4 抗体
  • wu:fb37g05 抗体
  • wu:fm61c07 抗体
  • wu:fq06c06 抗体
  • zgc:113704 抗体

Protein level used designations for CBS

cystathionine-beta-synthase , cystathionine beta-synthase , cystathionine beta-synthase CBS , beta-thionase , hemoprotein H-450 , serine sulfhydrase , methylcysteine synthase

GENE ID SPECIES
380308 Xenopus laevis
493533 Xenopus (Silurana) tropicalis
551341 Apis mellifera
736626 Pan troglodytes
3253577 Cryptococcus neoformans var. neoformans JEC21
3665875 Trypanosoma brucei brucei strain 927/4 GUTat10.1
4551426 Mycobacterium ulcerans Agy99
6228672 Mycobacterium marinum M
7006755 Rhodospirillum centenum SW
7705918 Gemmatimonas aurantiaca T-27
7712188 Rhodococcus erythropolis PR4
7746532 Rhodococcus opacus B4
8616308 Dictyostelium discoideum AX4
100136726 Oncorhynchus mykiss
100635325 Amphimedon queenslandica
24250 Rattus norvegicus
12411 Mus musculus
446655 Xenopus laevis
418545 Gallus gallus
875 Homo sapiens
611071 Canis lupus familiaris
514525 Bos taurus
100008766 Oryctolagus cuniculus
266987 Danio rerio
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