anti-Chromobox Homolog 1 (CBX1) 抗体

CBX1 encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . 再加上,我们可以发Chromobox Homolog 1 蛋白 (8)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
CBX1 12412 P83917
CBX1 10951 P83916
CBX1 360609  
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antibodies-online.cn销售最多的anti-Chromobox Homolog 1 抗体

Showing 10 out of 97 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB <b>WB Suggested Anti-CBX1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>OVCAR-3 cell lysate WB Suggested Anti-CBX1 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500 <br /> Positive Control: OVCAR-3 cell lysate <br /> CBX1 is supported by BioGPS gene expression data to be expressed in OVCAR3 100 μL Log in to see 2至3个工作日
Cow 非结合性 WB <b>WB Suggested Anti-CBX1 Antibody Titration: </b>1.25ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>HepG2 cell lysate WB Suggested Anti-CBX1 <br /> Antibody Titration: 1.25 µg/mL ELISA Titer: 1:62500 <br /> Positive Control: HepG2 cell lysate 100 μL Log in to see 2至3个工作日
非结合性 FACS, IHC (p), WB Western blot analysis of CBX1 Antibody (C-term) (ABIN652861) in MCF-7, A2058, Y79 cell line lysates (35 µg/lane). CBX1 (arrow) was detected using the purified polyclonal antibody. CBX1 Antibody (C-term) (ABIN652861) IHC analysis in formalin fixed and paraffin embedded brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10至11个工作日
山羊 非结合性 IHC, ELISA, WB ABIN185492 (0.3µg/ml) staining of A431 lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. ABIN185492 (2.5µg/ml) staining of paraffin embedded Human Placenta. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. 100 μg Log in to see 6至7个工作日
Bat 山羊 非结合性 IHC (p), ELISA, WB Human Placenta (formalin-fixed, paraffin-embedded) stained with CBX1 antibody ABIN337122 at 2.5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7至9个工作日
山羊 非结合性 IHC (p), IHC, ELISA, WB ABIN250825 (0.3ug/ml) staining of A431 lysate (35ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Western Blot: CBX1 Antibody [ABIN250825] - (0.3ug/ml) staining of A431 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 7至9个工作日
Bat 非结合性 WB 100 μg Log in to see 7至9个工作日
山羊 非结合性 EIA, IHC (p), WB 50 μg Log in to see 6至8个工作日
Bat 非结合性 WB 50 μg Log in to see 7至9个工作日
非结合性 ICC, IF, IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: Raji 12% SDS PAGE antibody diluted at 1:1000 IHC-P Image CBX1 / HP1 beta antibody detects CBX1 protein at nucleus on C2C12 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded C2C12 xenograft. CBX1 / HP1 beta antibody , dilution: 1:500. 100 μL Log in to see 1至2个工作日

通过反应活性、应用领域、克隆类型和共轭标记 CBX1 抗体

特性 应用范围 宿主 克隆类型 标记
Mouse (Murine) , ,
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Human , , ,
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Rat (Rattus) ,
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引用最多的anti-Chromobox Homolog 1 抗体

  1. Human Polyclonal CBX1 Primary Antibody for ChIPSeq, IF - ABIN2452034 : Kametaka, Takagi, Hayakawa, Haraguchi, Hiraoka, Yoneda: Interaction of the chromatin compaction-inducing domain (LR domain) of Ki-67 antigen with HP1 proteins. in Genes to cells : devoted to molecular & cellular mechanisms 2002 (PubMed)
    Show all 3 Pubmed References

  2. Human Monoclonal CBX1 Primary Antibody for ICC, IF - ABIN2668549 : Leshner, Wang, Lewis, Zheng, Chen, Santy, Wang: PAD4 mediated histone hypercitrullination induces heterochromatin decondensation and chromatin unfolding to form neutrophil extracellular trap-like structures. in Frontiers in immunology 2012 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal CBX1 Primary Antibody for IHC (p), IHC - ABIN250825 : Sharma, Hwang, Pandita, Gupta, Dhar, Parenteau, Agarwal, Worman, Wellinger, Pandita: Human heterochromatin protein 1 isoforms HP1(Hsalpha) and HP1(Hsbeta) interfere with hTERT-telomere interactions and correlate with changes in cell growth and response to ionizing radiation. in Molecular and cellular biology 2003 (PubMed)

  4. Cow (Bovine) Polyclonal CBX1 Primary Antibody for WB - ABIN2775787 : Ayoub, Jeyasekharan, Bernal, Venkitaraman: HP1-beta mobilization promotes chromatin changes that initiate the DNA damage response. in Nature 2008 (PubMed)

更多抗Chromobox Homolog 1的相互作用对抗体

Mouse (Murine) Chromobox Homolog 1 (CBX1) interaction partners

  1. We demonstrate an unexpected duality in the role of HP1b: it is essential in ESCs (显示 NR2E3 抗体) for maintaining pluripotency, while it is required for proper differentiation in differentiated cells.

  2. The N-terminal portion of LBR (显示 LBR 抗体) is probably responsible for the binding to HP1b.

  3. HP1b negatively regulates MMP2 (显示 MMP2 抗体) expression in a transcriptional level and prevents MMP2 (显示 MMP2 抗体) activation through reducing the expression of MT1MMP (显示 MMP14 抗体).

  4. Study concludes that only the 53BP1 (显示 TP53BP1 抗体) status in DNA lesions, induced by UVA or gamma-rays, is affected by A-type lamin (显示 LMNA 抗体) deficiency, which was not observed for heterochromatin-related proteins HP1beta and BMI1 (显示 BMI1 抗体).

  5. SUV39h1 (显示 SUV39H1 抗体) associated with HP1 beta in fibrillarin (显示 FBL 抗体)-positive nucleolar regions.

  6. demonstrate that a green fluorescent protein-HP1beta fusion protein is highly mobile within both the euchromatin and heterochromatin of ex vivo resting T cells; T cell activation greatly increased this mobility

  7. HP1 (显示 CBX5 抗体) isotypes have specific nonredundant functions; HP1 beta plays an essential role in the shuttling of corepressor transcriptional intermediary factor (TIF)1 (显示 TRIM24 抗体) beta from eu- to heterochromatin during cell differentiation in vivo.

  8. The localization, dynamics, and mobility of HP1beta in the in mouse preimplantation embryos (pro)nucleus were examined.

  9. HP1alpha (显示 CBX5 抗体) and HP1beta proteins on the heterochromatin of transcriptionally active oocytes and their absence in transcriptionally silent oocytes suggest that they are necessary for the repression of RNA synthesis in heterochromatin domains.

  10. HP1-beta is required for development of the cerebral neocortex and neuromuscular junctions

Human Chromobox Homolog 1 (CBX1) interaction partners

  1. the prolyl residue of the PXXVXL motif appears to play a role distinct from that of Pro in the known HP1beta CSD (显示 TGFBI 抗体)-PXVXL complexes.

  2. Data show that heterochromatin protein 1-beta (HP1beta) is a prototypic HP1 (显示 DEFA1 抗体) protein exemplifying most basal chromatin binding and effects.

  3. increased HP1beta expression is associated with the poor prognosis in breast cancer

  4. In this review, we summarize the current knowledge about targeting and functional mechanisms of PRCs, emphasizing the recent breakthroughs related to CBX proteins under a number of physiological and pathological conditions.

  5. Data suggest the reduction of Heterochromatin Protein 1 isoforms HP1beta followed by a decrease in HP1alpha (显示 CBX5 抗体) contributes to the pathogenesis of thyroid carcinomas, and their loss is a potential marker of thyroid malignancy and metastatic potential, respectively.

  6. Phosphorylation at Ser89 and Ser175 results in localized conformational changes in HP1beta that do not compromise the ability of the protein to bind chromatin.

  7. HP1 (显示 DEFA1 抗体) isoforms distinctly augment AR signaling and cell growth in prostate cancer. Therefore, silencing of HP1beta and HP1gamma (显示 CBX3 抗体) may be a promising therapeutic strategy for treatment of prostate cancer.

  8. The structural plasticity of HP1beta supports its ability to bind and connect a wide variety of binding partners in epigenetic processes.

  9. HP1beta which is associated with PCNA (显示 PCNA 抗体) in regions of DNA repair, is bound and does not exchange with the mobile pool, suggesting that HP1beta in association with PCNA (显示 PCNA 抗体) may be a component of a DNA repair complex.

  10. The HP1beta interactome is enriched with Lys (显示 LYZ 抗体) methylated proteins.Role of HP1beta in DNA damage response.

Chromobox Homolog 1 (CBX1) 抗原简介


This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene names and symbols associated with anti-Chromobox Homolog 1 (CBX1) 抗体

  • chromobox 1 (Cbx1) 抗体
  • chromobox 1 (CBX1) 抗体
  • chromobox 1 S homeolog (cbx1.S) 抗体
  • chromobox homolog 1a (HP1 beta homolog Drosophila) (cbx1a) 抗体
  • CBX 抗体
  • Cbx-rs2 抗体
  • cbx1 抗体
  • E430007M08Rik 抗体
  • HP1-BETA 抗体
  • HP1B 抗体
  • Hp1beta 抗体
  • HP1Hs-beta 抗体
  • HP1Hsbeta 抗体
  • M31 抗体
  • MOD1 抗体
  • p25beta 抗体
  • wu:fe14b09 抗体
  • zgc:55739 抗体

Protein level used designations for anti-Chromobox Homolog 1 (CBX1) 抗体

HP1 beta , chromobox homolog 1 , chromobox protein homolog 1 , heterochromatin protein 1 homolog beta , heterochromatin protein p25 , modifier 1 protein , HP1 beta homolog , chromobox homolog 1 (HP1 beta homolog Drosophila ) , heterochromatin protein 1-beta , heterochromatin protein p25 beta , chromobox homolog 1 (HP1 beta homolog) , chromobox-like protein 1

12412 Mus musculus
10951 Homo sapiens
491051 Canis lupus familiaris
360609 Rattus norvegicus
444708 Xenopus laevis
374237 Gallus gallus
616506 Bos taurus
326746 Danio rerio
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