PKC gamma 蛋白 (PRKCG)产品概述

在www.antibodies-online.cn可供18 Protein Kinase C, gamma (PRKCG) 蛋白的11不同的供货商。 再加上,我们可以发PKC gamma 抗体 (179)PKC gamma 试剂盒 (27)和数多这个蛋白质的别的产品。 总共234 PKC gamma产品已列进来了。
PKC, PKC-gamma, Pkcc, PKCG, PKCgamma, PKCI, Prkc, Prkcc, PRKCG, RATPKCI, SCA14
列出全部蛋白 基因 基因ID UniProt
PRKCG 5582 P05129
PRKCG 18752 P63318
PRKCG 24681 P63319

按照种类PKC gamma 蛋白 (PRKCG)

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Human Protein Kinase C, gamma (PRKCG) interaction partners

  1. Lysophosphatidylcholines prime polymorphonuclear neutrophil through Hck (显示 HCK 蛋白)-dependent activation of PKCdelta (显示 PKCd 蛋白), which stimulates PKCgamma, resulting in translocation of phosphorylated p47(phox).

  2. The gene-environment combination of PRKCG rs3745406 C allele, BDNF (显示 BDNF 蛋白) rs6265 G allele and high level of negative life events was significantly associated with major depressive disorder.

  3. Data suggest that PRKCG (protein kinase C gamma) phosphorylates TA isoforms of p63 (tumor protein p63 (显示 TP63 蛋白)) at Thr157 to stabilize them and promote cell apoptosis in tumor cells.

  4. PKCgamma,mutated in the neurodegenerative disease spinocerebellar ataxia (显示 USP14 蛋白) type 14 is a novel amyloidogenic protein.

  5. The rs454006 polymorphism of the PRKCG gene correlated to osteosarcoma susceptibility and might increase the risk of osteosarcoma.

  6. findings provide evidence for both an increased PKCgamma activity in Purkinje cells in vivo and for pathological changes typical for cerebellar disease thus linking increased and dysregulated activity of PKCgamma to development of cerebellar disease

  7. we show that the mutation V138E of the protein kinase C gamma (PKCgamma) C1B domain, which is implicated in spinocerebellar ataxia (显示 USP14 蛋白) type 14, exhibits a partially unfolded C-terminus

  8. PKCgamma plays a critical role in cancer cells, and simultaneous inhibition of PKCgamma and Hsp90alpha (显示 HSP90AA2 蛋白) synergistically prevents cell migration and promotes apoptosis in cancer cells.

  9. A novel missense mutation, F643L, which maps to a highly conserved amino acid of the catalytic domain of protein kinase C gamma, extends the phenotype associated with the spinocerebellar ataxia (显示 USP14 蛋白) type 14 (SCA14) locus.

  10. Spinocerebellar ataxia (显示 USP14 蛋白) type 14 mutant PKC-gamma upregulates Hsp70 (显示 HSP70 蛋白). Hsp70 (显示 HSP70 蛋白) has a role in degrading mutant PKC-gamma.

Mouse (Murine) Protein Kinase C, gamma (PRKCG) interaction partners

  1. Lysophosphatidylcholines prime polymorphonuclear neutrophil through Hck (显示 HCK 蛋白)-dependent activation of PKCdelta (显示 PKCd 蛋白), which stimulates PKCgamma, resulting in translocation of phosphorylated p47(phox).

  2. Immunoblotting and RT-PCR results showed that NIHL increased the expression of PKCgamma but decreased that of GABABR1 (显示 GABBR1 蛋白) and GABABR2 (显示 GABBR2 蛋白) at both protein and mRNA levels in the CNC

  3. Therefore, we propose that PKCgamma positively modulates dopamine release through beta2PIX phosphorylation.

  4. These findings indicate that the identity of the calcium-dependent PKCgamma that mediates PTP controls the mechanism and functional consequences of Posttetanic potentiation.

  5. This study provided new evidence to support the possibility of the involvement of PKC-gamma in the actions of volatile anesthetics in mice brain.

  6. demonstrate a role for the gamma isotype of protein kinase C (PKCgamma) in food-mediated entrainment of behavior and the molecular clock

  7. transient receptor potential 3 which is also needed for mGluR1 (显示 GRM1 蛋白)-dependent slow excitatory postsynaptic potentials and motor coordination and associates with PKCgamma

  8. Membrane residence time of PKCalpha (显示 PKCa 蛋白) after depolarization-induced translocation is significantly decreased when it is present with the mutant PKCgamma construct of spinocerebellar ataxia (显示 USP14 蛋白) type 14.

  9. cPLA(2 (显示 PLA2G4A 蛋白))-dependent AA release is required for VEGF (显示 VEGFA 蛋白)-induced Src (显示 SRC 蛋白)-PLD1-PKCgamma-mediated pathological retinal angiogenesis

  10. the expression of transthyretin and protein kinase Cgamma were increased in the prefrontal cortex but not in the hippocampus of naltrexone-treated mice

Rabbit Protein Kinase C, gamma (PRKCG) interaction partners

  1. Here, substitution studies on peptides correlating to the C1B domain in PKC gamma show that a flexible structure and ability to be phosphorylated on serine 109 are critical for this purpose.

蛋白简介PKC gamma (PRKCG)


Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14).

Alternative names and synonyms associated with PKC gamma (PRKCG)

  • protein kinase C, gamma (PRKCG)
  • protein kinase C, gamma (Prkcg)
  • PKC 蛋白
  • PKC-gamma 蛋白
  • Pkcc 蛋白
  • PKCG 蛋白
  • PKCgamma 蛋白
  • PKCI 蛋白
  • Prkc 蛋白
  • Prkcc 蛋白
  • PRKCG 蛋白
  • RATPKCI 蛋白
  • SCA14 蛋白

Protein level used designations for Protein Kinase C, gamma 蛋白 (PRKCG)

protein kinase C, gamma , protein kinase C gamma type-like , protein kinase C gamma type , PKC-gamma , protein kinase C type I (gamma type) , PKC-delta

456276 Pan troglodytes
100062549 Equus caballus
100137333 Papio anubis
100404028 Callithrix jacchus
100601464 Nomascus leucogenys
5582 Homo sapiens
18752 Mus musculus
24681 Rattus norvegicus
484316 Canis lupus familiaris
282002 Bos taurus
100009102 Oryctolagus cuniculus
100733947 Cavia porcellus
101116423 Ovis aries
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