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Human HMOX1 ELISA Kit for Sandwich ELISA - ABIN366536
Varol, Uzuno?lu, Erba?, Süt, Say?n: VEGFR-1, Bcl-2, and HO-1 Ratios in Pregnant Women With Hypertension. in Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 2015
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Mouse (Murine) HMOX1 ELISA Kit for Sandwich ELISA - ABIN424042
Wang, Wang: Senescence may mediate conversion of tau phosphorylation-induced apoptotic escape to neurodegeneration. in Experimental gerontology 2015
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Rat (Rattus) HMOX1 ELISA Kit for Sandwich ELISA - ABIN368210
Bijjem, Padi, lal Sharma: Pharmacological activation of heme oxygenase (HO)-1/carbon monoxide pathway prevents the development of peripheral neuropathic pain in Wistar rats. in Naunyn-Schmiedeberg's archives of pharmacology 2013
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study evaluated the time-course of HO-1 and catalase (显示 CAT ELISA试剂盒) gene expressions in nodules and roots of soybean plants subjected to cadmium treatment
Data suggest expression of hsp32 is up-regulated in kidney epithelial cells upon in vitro exposure to heavy metal water pollutants (Cd, As) or proteasomal inhibitors (MG132, withaferin A, celastrol); heat shock may be synergistic factor.
this study provides a better understanding of the role of the HO-1/Carbon monoxide system in controlling heart function in lower vertebrates.
The induced expression of HO-1 by fenofibrate appeared to be essential for mediating the protective effects of fenofibrate, as the inhibition of HO-1 activity significantly diminished the protective effects of fenofibrate against the GM-mediated death of sensory hair cells in cochlea
Suggest that Gata-1 (显示 GATA1 ELISA试剂盒) and Nrf2a (显示 NFE2L2 ELISA试剂盒) play differential roles in regulating the heme degradation enzymes hmox1a/bvra (显示 BLVRA ELISA试剂盒)/bvrb (显示 BLVRB ELISA试剂盒) during an early developmental period of heightened cellular stress.
Bach1 (显示 BACH1 ELISA试剂盒) regulates the liver specificity and transience of the Nrf2a (显示 NFE2L2 ELISA试剂盒)-dependent induction of hmox1a and that heme mediates this regulation through Bach1 (显示 BACH1 ELISA试剂盒) inhibition based on its level in each tissue.
Data indicate that Heme oxygenase 1 (HY1) functioned negatively and acted upstream of ABSCISIC ACID-INSENSITIVE4 (ABI4) in drought signaling.
HY1 confers cadmium tolerance by decreasing nitric oxide production and improving iron homeostasis.
Data indicate that AtHO1 (HY1; heme oxygenase-1)-overexpressing plants generated more NO, whereas knock-down of AtHO1 expression reduced the level of nitric oxide (NO) in plants.
HY1 mutant exhibited progressive salt hypersensitivity.
Disrupting the binding of the AtHBP5 to haem oxygenase 1 (HY1) leads to oxidative stress.
Mutation of HY1 causes UV-C hypersensitivity by impairing carotenoid and flavonoid biosynthesis and the down-regulation of antioxidant defence.
HY1 and HY5 additively regulate the expression of light regulated genes and accumulation of chlorophyll and anthocyanin during early seedling development.
HY1 (Heme oxygenase 1) plays an important role in salt acclimation.
all members of the HO1 subfamily (HY1, HO3 and HO4) are active monomeric HOs and can convert haem to BV IXalpha using spinach Fd (ferredoxin) as an electron donor
HO2 (显示 HMOX2 ELISA试剂盒) has an activity high enough to substitute for HO1 under aerobic conditions.
The induction of HO-1 expression by proteasome inhibition was reduced in PINK1 G309D mutant cells.
there was little difference in HMOX1 genotypes distribution in patients with chronic obstructive pulmonary disease with different severity.
investigation of the possible role of HMOX1 in adipose tissue, adipogenesis and iron metabolism; adipose tissue HMOX1 was increased in obese participants and positively associated with obesity-related metabolic disturbances, and markers of iron accumulation, inflammation and oxidative stress
the HO-1 interactome in prostate cancer, is identified.
induction of HO1 by M. tuberculosis infection may be a mycobacterial virulence mechanism to enhance inflammation and bacterial growth
Data (including data from studies using cells from knockout mice) confirm that the NRF2 (显示 GABPA ELISA试剂盒)/HMOX1 axis is a critical pathway in the hyperglycemic-mediated dysregulation and inflammatory features of chondrocytes in type 2 diabetes-associated osteoarthritis. (NRF2 (显示 GABPA ELISA试剂盒) = nuclear factor [erythroid-derived 2]-like 2 protein; HMOX1 = heme oxygenase [decycling] 1)
To promote intracellular iron flux, an iron chaperone appears to be essential for receiving iron from heme catabolism. Data suggest that PCBP2 (显示 PCBP2 ELISA试剂盒) competes with CPR (显示 POR ELISA试剂盒) for binding HO1; PCBP2 (显示 PCBP2 ELISA试剂盒) K homology 3 domain is important for HO1/PCBP2 (显示 PCBP2 ELISA试剂盒) interaction; heme prompts HO1/CPR (显示 POR ELISA试剂盒) multimer and decreases HO1/PCBP2 (显示 PCBP2 ELISA试剂盒) multimer. [PCBP2 (显示 PCBP2 ELISA试剂盒) = poly(rC) binding protein 2 (显示 PCBP2 ELISA试剂盒); CPR (显示 POR ELISA试剂盒) = cytochrome P450 reductase (显示 POR ELISA试剂盒); HO1 = heme oxidase 1]
Mechanistically, HO-1 induction by all CRLPs requires NADPH oxidase 4 (显示 NOX4 ELISA试剂盒), with PUFA-containing particles additionally dependent upon mitochondrial reactive oxygen species.These studies define new molecular pathways coupling endothelial cell activation by model CMRs with adaptive regulation of Nrf2 (显示 GABPA ELISA试剂盒)-dependent HO-1 expression
We identified miR (显示 MLXIP ELISA试剂盒)-1254 as a negative regulator inhibiting HO-1 translation by directly targeting HO-1 3'UTR (显示 UTS2R ELISA试剂盒) via its seed region, and suppressing HO-1 transcription via non-seed region-dependent inhibition of transcriptional factor AP-2 alpha (TFAP2A (显示 TFAP2A ELISA试剂盒)), a transcriptional activator of HO-1.
cells with elevated HO-1 produced less reactive oxygen species, resulting in nuclear localization of HDAC4 (显示 HDAC4 ELISA试剂盒) and miR (显示 MLXIP ELISA试剂盒)-206 repression.
findings collectively suggest that miR (显示 MYLIP ELISA试剂盒)-506 acts as a tumor suppressor via regulation of ROCK1 (显示 ROCK1 ELISA试剂盒) expression and may thus be a promising therapeutic target for HCC (显示 FAM126A ELISA试剂盒)
Exogenous administration of CO exacerbated allergic symptoms, resulting in higher levels of both CO and heme oxygenase-1 expression, and a further reduction in H2S levels and CSE expression.
Down-regulation of HO-1 is associated with pulmonary arterial hypertension and right ventricular failure.
The study revealed the involvement of HO-1 in classical swine fever virus proliferation.
The protective properties of flavonoids, such as EGCG, against endothelial inflammation may be regulated in part though induction of HO-1 and subsequent activator protein-1 signaling.
Glutamate (显示 GRIN2C ELISA试剂盒) regulates Ca2 (显示 CA2 ELISA试剂盒)+ signals in smooth muscle cells of newborn piglet brain slice arterioles through astrocyte- and heme oxygenase-dependent mechanisms.
obalt protoporphyrin prevents postictal cerebral vascular dysfunction by upregulating HO-1.
Data demonstrate that lipopolysaccharides evoke a heat shock response, with an increase heat shock proteins 70 and Hsp32) and of VEGF (显示 VEGFA ELISA试剂盒), a specific endothelial cell growth factor (显示 FGF1 ELISA试剂盒).
Interaction of soluble factors in plasma possibly generated during PICSO are not responsible for upregulation of HO-1 and VEGF mRNA.
the data were consistent with HO-1 acting as an anti-viral factor and these findings suggested that induction of HO-1 may be a useful prevention and treatment strategy against BVDV infection.
These findings suggest that bronchiolar epithelial cells and macrophages up-regulate Nrf2 (显示 NFE2L2 ELISA试剂盒) expression early in the course of infection, which results in increased expression of HO-1 within these cells.
investigation of molecular mechanisms of microvascular complications in diabetes/hyperglycemia: regulation of HO-1 gene expression in aortic endothelial cells by advanced glycation end products
Sickle blood increases endothelial heme oxygenase activity.
data provide evidence for the involvement of the thioredoxin/thioredoxin (显示 TXN ELISA试剂盒) receptor system, in the regulation of haem oxygenase-1 expression in aortic endothelial cells during pro-oxidant challenge
Heme oxygenase-1 induction modulates hypoxic pulmonary vasoconstriction through upregulation of ecSOD/SOD3 (显示 SOD3 ELISA试剂盒).
Results establish an essential role for the receptor CX3CR1 (显示 CX3CR1 ELISA试剂盒) in gut (显示 GUSB ELISA试剂盒) macrophages in resolving inflammation in the intestine, where it helps protects against colitis-associated cancer by regulating HMOX-1 expression.
study demonstrates that human respiratory syncytial virus (hRSV) infection can be modulated by the expression of HO-1 both in vitro and in vivo; thus, HO-1 activity may play a critical role during hRSV infection
This is the first study to dissect the mechanism by which the antiadipogenic and anti-inflammatory lipid, Epoxyeicosatrienoic acid, induces the PGC-1alpha (显示 PPARGC1A ELISA试剂盒) signaling cascade and reprograms the adipocyte phenotype by regulating mitochondrial function and HO-1 expression.
The findings suggest that HO-1 by modulating TLR9 (显示 TLR9 ELISA试剂盒) expression in PMCs promotes pleural innate immunity in MRSA (显示 MSR1 ELISA试剂盒) empyema.
HO-1 regulates not only cytokine/chemokine (显示 CCL1 ELISA试剂盒) production in pregnant uteri but also myeloid cell receptor numbers.
Administration of EET alters Wnt1 (显示 WNT1 ELISA试剂盒), NOV (显示 NOV ELISA试剂盒), and HO-1 signaling to prevent obesity-induced cardiomyopathy in obese mice.
Studied the immunosuppressive role of HO-1 in sepsis with a focus on its effects on helper T-cell (Th) differentiation and regulatory T cells; found overexpressed HO-1 contributes to sepsis-induced immunosuppression by inducing a Th1 (显示 HAND1 ELISA试剂盒) to Th2 cytokine shift and enhancing Treg function.
Data indicate that chlorogenic acid (CGA (显示 CGA ELISA试剂盒)) protected osteoblast MC3T3-E1 cells against oxidative damage via PI3K/Akt (显示 AKT1 ELISA试剂盒)-mediated activation of Nrf2 (显示 NFE2L2 ELISA试剂盒)/HO-1 pathway, which may be an effective drug in treatment of osteoporosis.
our data suggest that the B. pseudomallei-mediated induction of HO-1 and the release of its metabolite carbon dixode impair bacterial clearance in macrophages and during murine melioidosis.
HO-1 activation mediates early brain damage after ICH (显示 ACE ELISA试剂盒) (intracerebral hemorrhage) but promotes neurologic function recovery in the later stage of ICH (显示 ACE ELISA试剂盒)
Kidneys from circulation-restricted fetuses showed reduced heme oxygenase-1 mRNA.
Ligustrazine injection possesses notable protective effects on ischemia/reperfusion injury in rabbits by increasing the expression of HO-1 in lung.
Results add new evidence for the importance of HO-1 in the genesis and development of atherosclerosis and provide several possible mechanisms underlying the anti-atherosclerosis effects of HO-1
the effect of HO-1 on the progression and stabilization of vulnerable plaques and the possible mechanism
Heme-L-lysinate could attenuate atherosclerotic progression through upregulating HO-1 and HSP70 (显示 HSP70 ELISA试剂盒) expression and increasing CO production.
These results suggest that HO-1 is important in limiting in-stent stenosis and can be regarded as a new therapeutic target.
Statins showed anti-atherosclerotic effects mediated by HO-1/eNOS (显示 NOS3 ELISA试剂盒), restoring the [NO]/[ONOO(-)] imbalance and reducing lipid peroxidation.
HO-1/CO system was activated and may be one of the protective signal pathway during pulmonary ischemia-reperfusion injury in rabbits.
HO-1 contributes to vascular repair by increasing circulating endothelial progenitor cells (EPCs) derived from the bone marrow.
Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family.
heme oxygenase (decycling) 1
, heme oxygenase 1
, heme oxygenase
, Heme oxygenase
, heat shock protein, 32-kD
, heat shock protein 32
, heme oxygenase (decyclizing) 1
, P32 protein
, heme oxygenase-1