anti-LIG1 (LIG1) 抗体产品概述

在www.antibodies-online.cn可供142 Ligase I, DNA, ATP-Dependent (LIG1) 抗体的19不同的供货商。 再加上,我们可以发LIG1 试剂盒 (7)LIG1 蛋白 (6)和数多这个蛋白质的别的产品。 总共165 LIG1产品已列进来了。
别名:
AL033288, ATLIG1, DNA ligase 1, lig1, LigI, T6D22.23, wu:fc54a11
列出全部抗体 基因 基因ID UniProt
LIG1 3978 P18858
LIG1 16881 P37913
LIG1 81513  

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抗Human LIG1 抗体:

抗Mouse (Murine) LIG1 抗体:

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更多抗LIG1的相互作用对抗体

Arabidopsis thaliana Ligase I, DNA, ATP-Dependent (LIG1) interaction partners

  1. The AtLIG1 is an important component of the active DNA demethylation machinery.

  2. LIG1 is required for both single-nucleotide or long-patch base excision repair.

  3. In the study, we show that loss-of-function of the major DNA LIGASE I (AtLIG1) in Arabidopsis thaliana causes maternal effects in the endosperm, which is the seed tissue that nurtures embryo development.

  4. Nuclear or mitochondrial targeting of LIG1 is accomplished through an evolutionarily conserved translation initiation mechanism. [AtLIG1]

  5. DNA ligase 1 functions in both DNA replication and in repair of both ss and dsDNA strand breaks.

Human Ligase I, DNA, ATP-Dependent (LIG1) interaction partners

  1. A histone H3K9-like mimic within LIG1 is methylated by G9a (显示 EHMT2 抗体) and GLP (显示 RCBTB1 抗体) and avidly binds UHRF1 (显示 UHRF1 抗体). Interaction with methylated LIG1 promotes the recruitment of UHRF1 (显示 UHRF1 抗体) to DNA replication sites and is required for DNA methylation (显示 HELLS 抗体) maintenance.

  2. The rs156641 polymorphism of DNA ligase 1 (LIG1) was significantly associated with lung cancer risk, whereas no association was found between rs3730931/rs439132/rs20579 polymorphisms and lung cancer.

  3. Data suggest that DNA ligase I (LigI)-deficient 46BR.1G1 cells represent a model to investigate the biological effects of sub-lethal levels of DNA insults.

  4. The LIG1 CC genotype was associated with susceptibility to non-small cell lung cancer, and the AA genotype demonstrated increased radiosensitivity compared to the AC and CC genotypes.

  5. Ppolymorphisms in LIG1 affect its expression and may therefore change its function.

  6. there is no association between LIGI polymorphisms and cervical cancer risk. However, they may be playing an important role in modulating the risk of cervical adenocarcinoma in North Indian women

  7. DNA ligase I also interacts with replication factor C, the factor that loads the PCNA (显示 PCNA 抗体) trimeric ring onto DNA.

  8. Data indicate that Ku70 (显示 XRCC6 抗体)/Ku80 (显示 XRCC5 抗体) facilitates the cooperative binding of multiple XRCC4 (显示 XRCC4 抗体)/Ligase IV (XL) and XLF (显示 NHEJ1 抗体) molecules to DNA.

  9. Single nucleotide polymorphisms in LIG1 are associated with myelodysplastic syndromes.

  10. phosphorylation of serine 51 on hLigI plays a critical role in regulating the interaction between hLigI and RFC (显示 RFC1 抗体), which is required for efficient DNA replication and repair.

Mouse (Murine) Ligase I, DNA, ATP-Dependent (LIG1) interaction partners

  1. Increased presynaptic glutamate (显示 GRIN1 抗体) release is a key early event resulting from Lgi1 (显示 LGI1 抗体)-deficiency, which likely contributes to epileptogenesis.

  2. Lig1 (显示 Lrig1 抗体) is not absolutely required for cellular DNA replication and repair in Lig1 (显示 Lrig1 抗体)-null cell line.

  3. LigI has a highly specific role in CTG repeat maintenance in the maternal germline, involved in mediating CTG expansions and in the avoidance of maternal CTG contractions.

  4. DNA ligase I null mouse cells show normal DNA repair activity but altered DNA replication and reduced genome stability.

LIG1 抗原简介

Antigen Summary

LIG1 encodes DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents.

Alternative names and synonyms associated with LIG1

  • ligase I, DNA, ATP-dependent (LIG1) 抗体
  • DNA ligase 1 (PB000674.02.0) 抗体
  • DNA ligase 1 (PTRG_06243) 抗体
  • DNA ligase 1 (PKH_140260) 抗体
  • DNA ligase 1 (LIG1) 抗体
  • ligase I, DNA, ATP-dependent (lig1) 抗体
  • ligase I, DNA, ATP-dependent (Lig1) 抗体
  • Protein LIG-1 (lig-1) 抗体
  • si:dkeyp-35b8.5 (si:dkeyp-35b8.5) 抗体
  • AL033288 抗体
  • ATLIG1 抗体
  • DNA ligase 1 抗体
  • lig1 抗体
  • LigI 抗体
  • T6D22.23 抗体
  • wu:fc54a11 抗体

Protein level used designations for LIG1

DNA ligase 1 , polydeoxyribonucleotide synthase [ATP] 1 , DNA ligase (ATP) 1 , DNA ligase I , LIG1, ligase I, DNA, ATP-dependent

GENE ID SPECIES
100053186 Equus caballus
3425646 Plasmodium berghei ANKA
6344500 Pyrenophora tritici-repentis Pt-1C-BFP
7323359 Plasmodium knowlesi strain H
837333 Arabidopsis thaliana
3978 Homo sapiens
100124507 Bos taurus
397978 Xenopus laevis
100686967 Canis lupus familiaris
16881 Mus musculus
81513 Rattus norvegicus
100520434 Sus scrofa
179502 Caenorhabditis elegans
556995 Danio rerio
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