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anti-CD247 (CD247) 抗体产品概述

Full name:
anti-CD247 Molecule 抗体 (CD247)
在www.antibodies-online.cn可供273 CD247 Molecule (CD247) 抗体的23不同的供货商。 再加上,我们可以发CD247 蛋白 (12)CD247 试剂盒 (6)和数多这个蛋白质的别的产品。 总共302 CD247产品已列进来了。
别名:
4930549J05Rik, A430104F18Rik, AW552088, Cd3, Cd3-eta, CD3-ZETA, CD3H, CD3Q, Cd3z, Cd3zeta, CD247, im:7156386, LOC100136514, LOC100136549, LOC100305023, T3Z, Tcrk, TCRZ, TCRzeta

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引用最多的anti-CD247 抗体

  1. Human Polyclonal CD247 Primary Antibody for IHC (fro), IHC (p) - ABIN115429 : Henry, Bennett, Piggott, Levett, May, Westley: Expression of the pNR-2/pS2 protein in diverse human epithelial tumours. in British journal of cancer 1991 (PubMed)
    Show all 5 references for ABIN115429

  2. Human Polyclonal CD247 Primary Antibody for WB - ABIN4620516 : Miyagawa, Yamai, Sakaguchi, Kiyohara, Tsukamoto, Kimoto, Nakamura, Lee, Tsai, Chiang, Shimoda, Harada, Tahira, Hayashi, Horiuchi: Association of polymorphisms in complement component C3 gene with susceptibility to systemic lupus erythematosus. in Rheumatology (Oxford, England) 2008 (PubMed)
    Show all 3 references for ABIN4620516

  3. Human Monoclonal CD247 Primary Antibody for EIA, IHC (fro) - ABIN118361 : van Oers, Teh, Irving, Tiong, Weiss, Teh: Production and characterization of monoclonal antibodies specific for the murine T cell receptor zeta chain. in Journal of immunological methods 1994 (PubMed)

  4. Human Monoclonal CD247 Primary Antibody for ICS - ABIN1177046 : Alberola-Ila, Takaki, Kerner, Perlmutter: Differential signaling by lymphocyte antigen receptors. in Annual review of immunology 1997 (PubMed)

  5. Human Monoclonal CD247 Primary Antibody for IP, WB - ABIN967304 : Hussey, Clayton, Diener, McConkey, Howard, Rodewald, DAdamio, Dallenbach, Stein, Schmidt: Overexpression of CD3 eta during thymic development does not alter the negative selection process. in Journal of immunology (Baltimore, Md. : 1950) 1993 (PubMed)

更多抗CD247的相互作用对抗体

Zebrafish CD247 Molecule (CD247) interaction partners

  1. The structure of the adaptor protein cd3zeta has been identified in the zebrafish genome.

Mouse (Murine) CD247 Molecule (CD247) interaction partners

  1. Comprehensive Survey of miRNA-mRNA Interactions Reveals That Ccr7 (显示 CCR7 抗体) and Cd247 (CD3 zeta) are Posttranscriptionally Controlled in Pancreas Infiltrating T Lymphocytes of Non-Obese Diabetic (NOD) Mice

  2. There is an early (within seconds) interaction between CD3zeta and the coreceptor CD8 that is independent of the binding of CD8 to MHC.

  3. The resting TCR localized in the disordered domain of giant plasma membrane (PM) vesicles (GPMVs) and PM spheres (PMSs) and single and nanoclustered TCRs are found in the high-density fractions in sucrose gradients.

  4. When Ly108 (显示 SLAMF6 抗体) is engaged in trans during cell-cell interactions, Ly108 (显示 SLAMF6 抗体)-CD3zeta interactions are promoted in a manner that uniquely depends on Ly108 (显示 SLAMF6 抗体) TM domain, leading to more efficient CD3zeta dephosphorylation.

  5. Two transcription factor binding sites and a long non-coding RNA are identified within the Cd247 gene.

  6. Zfat (显示 ZFAT 抗体)-deficiency results in a loss of CD3zeta phosphorylation with dysregulation of ERK (显示 EPHB2 抗体) and Egr (显示 EGR1 抗体) activities leading to impaired positive selection.

  7. The results of this study supported the model that the procognitive function of CD3zeta may be mediated through its involvement in the NMDAR (显示 GRIN1 抗体) downstream signaling pathway leading to CaMKII (显示 CAMK2G 抗体)-dependent LTP (显示 SCP2 抗体) induction.

  8. T cell CD3zeta deficiency enables multiorgan tissue inflammation.

  9. Tyrosine phosphorylation of the TCR-zeta cytoplasmic domain regulates its association with the plasma membrane

  10. The data of this study suggested that CD3zeta mediates the ZAP-70 (显示 ZAP70 抗体)/Syk (显示 SYK 抗体) kinase activation triggered by ephrinA-activated pathway to regulate early neuronal morphogenesis.

Human CD247 Molecule (CD247) interaction partners

  1. Linkage and association studies revealed a chromosomal region in which a novel type 1 diabetes (T1D)/autoimmune thyroid disease (AITD) susceptibility gene, CD247, is located and showed association between T1D/AITD and several variants in this gene. These results suggests that common susceptibility genes act in concert with variants of CD247 to generate genetic risk for T1D/AITD in this population.

  2. Suggest 2'5'-oligoadenylate synthetase 2 mediates T-cell receptor CD3-zeta chain down-regulation via caspase-3 (显示 CASP3 抗体) activation in oral cancer.

  3. SRSF1 (显示 SRSF1 抗体) regulates CD3zeta expression in human T cells and may contribute to the T cell defect in systemic lupus erythematosus.

  4. In localized colorectal cancer carriers, mRNA-based CD3Z/CD8 (显示 CD8A 抗体) profiling of tumor immune response may have stage, site and tissue-specific prognostic significance, along with ESR1 (显示 ESR1 抗体) expression.

  5. Our study independently confirms and extends the association of SLE with CD247, which is shared by various autoimmune disorders and supports a common T-cell-mediated mechanism.

  6. we observed decreased CD3 (显示 CD3 抗体) surface expression, reduced ZAP-70 (显示 ZAP70 抗体) abundance and increased histone H3 (显示 HIST3H3 抗体)-acetylation in activated T lymphocytes after 5 minutes of clinorotation and a transient downregulation of CD3 (显示 CD3 抗体) and stable downregulation of IL-2R

  7. T cell receptor (TCR)-CD3 (显示 CD3 抗体) complex and the Lck (显示 LCK 抗体) kinase were required for Ca(2 (显示 CA2 抗体)+) mobilization but not for apoptosis induction in Jurkat cells.

  8. These findings confirm the role of PTPN22 (显示 PTPN22 抗体) and CD28 (显示 CD28 抗体) involved in the T cell activation pathway in the development of T1D in Tunisian families. Interestingly, ZAP70 (显示 ZAP70 抗体) and TCRbeta/CD3z seem to contribute to the susceptibility to the disease in our population.

  9. a CD247 defect leads to the accumulation of naive, hyporesponsive gammadelta and alphabeta T cells in thymoma patient resulting in a novel type of acquired T cell immunodeficiency and immune dysregulation of clinical significance.

  10. CD247 downregulation was associated with disease severity, complications, and the occurrence of future cardiovascular events, suggesting its potential use not only as a diagnostic but also as a prognostic biomarker.

Pig (Porcine) CD247 Molecule (CD247) interaction partners

CD247 抗原简介

Antigen Summary

The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Alternative names and synonyms associated with CD247

  • CD247 antigen like (cd247l) 抗体
  • CD3zeta-2 (LOC100136514) 抗体
  • CD3zeta-1 (LOC100136549) 抗体
  • CD3 zeta (LOC100305023) 抗体
  • CD247 molecule (CD247) 抗体
  • CD247 antigen (cd247) 抗体
  • CD247 antigen (Cd247) 抗体
  • Cd247 molecule (Cd247) 抗体
  • 4930549J05Rik 抗体
  • A430104F18Rik 抗体
  • AW552088 抗体
  • Cd3 抗体
  • Cd3-eta 抗体
  • CD3-ZETA 抗体
  • CD3H 抗体
  • CD3Q 抗体
  • Cd3z 抗体
  • Cd3zeta 抗体
  • CD247 抗体
  • im:7156386 抗体
  • LOC100136514 抗体
  • LOC100136549 抗体
  • LOC100305023 抗体
  • T3Z 抗体
  • Tcrk 抗体
  • TCRZ 抗体
  • TCRzeta 抗体

Protein level used designations for anti-CD247 Molecule (CD247) 抗体

CD247 antigen like , cd3zetal , CD3zeta-like , CD247 antigen-like , CD3zeta-2 , T-cell surface glycoprotein CD3 zeta chain , CD3zeta-1 , CD3 zeta , CD247 molecule , cd3zeta , CD3 antigen, zeta polypeptide , CD3-zeta/eta , T-cell receptor T3 eta chain , CD247 antigen, zeta subunit , CD3Z antigen, zeta polypeptide (TiT3 complex) , CD3zeta chain , T-cell antigen receptor complex, zeta subunit of CD3 , T-cell receptor T3 zeta chain , TCR zeta chain , CD247 antigen , T-cell receptor CD3 subunit zeta , T-cell receptor CD3, subunit zeta , CD3 zeta chain , CD3 Zeta chain

GENE ID SPECIES
100101465 Danio rerio
100136514 Salmo salar
100136549 Salmo salar
100305023 Ictalurus punctatus
748272 Pan troglodytes
100101654 Danio rerio
12503 Mus musculus
919 Homo sapiens
25300 Rattus norvegicus
397302 Sus scrofa
100008617 Oryctolagus cuniculus
443436 Ovis aries
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