anti-CD247 (CD247) 抗体产品概述

Full name:
anti-CD247 Molecule 抗体 (CD247)
在www.antibodies-online.cn可供299 CD247 Molecule (CD247) 抗体的26不同的供货商。 再加上,我们可以发CD247 蛋白 (13)CD247 试剂盒 (6)和数多这个蛋白质的别的产品。 总共329 CD247产品已列进来了。
别名:
4930549J05Rik, A430104F18Rik, AW552088, Cd3, Cd3-eta, CD3-ZETA, CD3H, CD3Q, Cd3z, Cd3zeta, CD247, im:7156386, LOC100136514, LOC100136549, LOC100305023, T3Z, Tcrk, TCRZ, TCRzeta

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引用最多的anti-CD247 抗体

  1. Human Polyclonal CD247 Primary Antibody for IHC (fro), IHC (p) - ABIN115429 : Henry, Bennett, Piggott, Levett, May, Westley: Expression of the pNR-2/pS2 protein in diverse human epithelial tumours. in British journal of cancer 1991 (PubMed)
    Show all 5 references for 115429

  2. Mouse (Murine) Monoclonal CD247 Primary Antibody for FACS - ABIN4898315 : Lin, Xu, Jin, Zhong, Di, Lin: CXCL12 enhances exogenous CD4+CD25+ T cell migration and prevents embryo loss in non-obese diabetic mice. in Fertility and sterility 2009 (PubMed)
    Show all 2 references for 4898315

  3. Mouse (Murine) Monoclonal CD247 Primary Antibody for FACS - ABIN4898307 : Lemay, Rintoul, Kus, Paterson, Garcia, Falls, Ferreira, Bridle, Conrad, Tang, Diallo, Arulanandam, Le Boeuf, Garson, Vanderhyden, Stojdl, Lichty, Atkins, Parato, Bell, Auer: Harnessing oncolytic virus-mediated antitumor immunity in an infected cell vaccine. in Molecular therapy : the journal of the American Society of Gene Therapy 2012 (PubMed)

  4. Human Monoclonal CD247 Primary Antibody for IP, WB - ABIN967304 : Hussey, Clayton, Diener, McConkey, Howard, Rodewald, DAdamio, Dallenbach, Stein, Schmidt: Overexpression of CD3 eta during thymic development does not alter the negative selection process. in Journal of immunology (Baltimore, Md. : 1950) 1993 (PubMed)

  5. Human Monoclonal CD247 Primary Antibody for ICS - ABIN1177046 : Alberola-Ila, Takaki, Kerner, Perlmutter: Differential signaling by lymphocyte antigen receptors. in Annual review of immunology 1997 (PubMed)

  6. Human Monoclonal CD247 Primary Antibody for FACS - ABIN118360 : van Oers, Teh, Irving, Tiong, Weiss, Teh: Production and characterization of monoclonal antibodies specific for the murine T cell receptor zeta chain. in Journal of immunological methods 1994 (PubMed)

更多抗CD247的相互作用对抗体

Zebrafish CD247 Molecule (CD247) interaction partners

  1. The structure of the adaptor protein cd3zeta has been identified in the zebrafish genome.

Mouse (Murine) CD247 Molecule (CD247) interaction partners

  1. ITAM sequence diversity is required for optimal TCR signal transduction and subsequent T cell maturation

  2. Comprehensive Survey of miRNA-mRNA Interactions Reveals That Ccr7 (显示 CCR7 抗体) and Cd247 (CD3 zeta) are Posttranscriptionally Controlled in Pancreas Infiltrating T Lymphocytes of Non-Obese Diabetic (NOD) Mice

  3. There is an early (within seconds) interaction between CD3zeta and the coreceptor CD8 that is independent of the binding of CD8 to MHC.

  4. The resting TCR localized in the disordered domain of giant plasma membrane (PM) vesicles (GPMVs) and PM spheres (PMSs) and single and nanoclustered TCRs are found in the high-density fractions in sucrose gradients.

  5. When Ly108 (显示 SLAMF6 抗体) is engaged in trans during cell-cell interactions, Ly108 (显示 SLAMF6 抗体)-CD3zeta interactions are promoted in a manner that uniquely depends on Ly108 (显示 SLAMF6 抗体) TM domain, leading to more efficient CD3zeta dephosphorylation.

  6. Two transcription factor binding sites and a long non-coding RNA are identified within the Cd247 gene.

  7. Zfat (显示 ZFAT 抗体)-deficiency results in a loss of CD3zeta phosphorylation with dysregulation of ERK (显示 EPHB2 抗体) and Egr (显示 EGR1 抗体) activities leading to impaired positive selection.

  8. The results of this study supported the model that the procognitive function of CD3zeta may be mediated through its involvement in the NMDAR (显示 GRIN1 抗体) downstream signaling pathway leading to CaMKII (显示 CAMK2G 抗体)-dependent LTP (显示 SCP2 抗体) induction.

  9. T cell CD3zeta deficiency enables multiorgan tissue inflammation.

  10. Tyrosine phosphorylation of the TCR-zeta cytoplasmic domain regulates its association with the plasma membrane

Human CD247 Molecule (CD247) interaction partners

  1. CD3 (显示 CD3 抗体)/28-activated T cells expanded in IL-7 (显示 IL7 抗体) and IL-15 (显示 IL15 抗体) produced greater expansion of memory stem T cells and central memory T cell-derived T cells compared with IL-2 (显示 IL2 抗体). Our strategy provides a powerful tool to elucidate the characteristics of CAR-modified T cells, regardless of the protocol used for expansion, reveals the functional properties of each expanded T cell subset.

  2. Multiple mutations were found in CD247 complementary DNAs (cDNAs) cloned from the patient as well as in cDNA and genomic DNA from other individuals, suggesting that genetic variation in this gene is frequent.

  3. Single-nucleotide polymorphism in CD247 gene is associated with sclerotic graft-versus-host disease.

  4. CD3Z hypermethylation was significantly correlated with SLE. CD3Z hypermethylation is an SLE risk factor that can be modified by environmental factors and is associated with more severe SLE clinical manifestations, which are related to deranged T cell function by downregulating the CD3zeta-chain.

  5. Linkage and association studies revealed a chromosomal region in which a novel type 1 diabetes (T1D)/autoimmune thyroid disease (AITD) susceptibility gene, CD247, is located and showed association between T1D/AITD and several variants in this gene. These results suggests that common susceptibility genes act in concert with variants of CD247 to generate genetic risk for T1D/AITD in this population.

  6. Suggest 2'5'-oligoadenylate synthetase 2 mediates T-cell receptor CD3-zeta chain down-regulation via caspase-3 (显示 CASP3 抗体) activation in oral cancer.

  7. SRSF1 (显示 SRSF1 抗体) regulates CD3zeta expression in human T cells and may contribute to the T cell defect in systemic lupus erythematosus.

  8. In localized colorectal cancer carriers, mRNA-based CD3Z/CD8 (显示 CD8A 抗体) profiling of tumor immune response may have stage, site and tissue-specific prognostic significance, along with ESR1 (显示 ESR1 抗体) expression.

  9. Our study independently confirms and extends the association of SLE with CD247, which is shared by various autoimmune disorders and supports a common T-cell-mediated mechanism.

  10. we observed decreased CD3 (显示 CD3 抗体) surface expression, reduced ZAP-70 (显示 ZAP70 抗体) abundance and increased histone H3 (显示 HIST3H3 抗体)-acetylation in activated T lymphocytes after 5 minutes of clinorotation and a transient downregulation of CD3 (显示 CD3 抗体) and stable downregulation of IL-2R

Pig (Porcine) CD247 Molecule (CD247) interaction partners

CD247 抗原简介

Antigen Summary

The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Alternative names and synonyms associated with CD247

  • CD247 antigen like (cd247l) 抗体
  • CD3zeta-2 (LOC100136514) 抗体
  • CD3zeta-1 (LOC100136549) 抗体
  • CD3 zeta (LOC100305023) 抗体
  • CD247 molecule (CD247) 抗体
  • CD247 antigen (cd247) 抗体
  • CD247 antigen (Cd247) 抗体
  • Cd247 molecule (Cd247) 抗体
  • 4930549J05Rik 抗体
  • A430104F18Rik 抗体
  • AW552088 抗体
  • Cd3 抗体
  • Cd3-eta 抗体
  • CD3-ZETA 抗体
  • CD3H 抗体
  • CD3Q 抗体
  • Cd3z 抗体
  • Cd3zeta 抗体
  • CD247 抗体
  • im:7156386 抗体
  • LOC100136514 抗体
  • LOC100136549 抗体
  • LOC100305023 抗体
  • T3Z 抗体
  • Tcrk 抗体
  • TCRZ 抗体
  • TCRzeta 抗体

Protein level used designations for anti-CD247 Molecule (CD247) 抗体

CD247 antigen like , cd3zetal , CD3zeta-like , CD247 antigen-like , CD3zeta-2 , T-cell surface glycoprotein CD3 zeta chain , CD3zeta-1 , CD3 zeta , CD247 molecule , cd3zeta , CD3 antigen, zeta polypeptide , CD3-zeta/eta , T-cell receptor T3 eta chain , CD247 antigen, zeta subunit , CD3Z antigen, zeta polypeptide (TiT3 complex) , CD3zeta chain , T-cell antigen receptor complex, zeta subunit of CD3 , T-cell receptor T3 zeta chain , TCR zeta chain , CD247 antigen , T-cell receptor CD3 subunit zeta , T-cell receptor CD3, subunit zeta , CD3 zeta chain , CD3 Zeta chain

GENE ID SPECIES
100101465 Danio rerio
100136514 Salmo salar
100136549 Salmo salar
100305023 Ictalurus punctatus
748272 Pan troglodytes
100101654 Danio rerio
12503 Mus musculus
919 Homo sapiens
25300 Rattus norvegicus
397302 Sus scrofa
100008617 Oryctolagus cuniculus
443436 Ovis aries
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