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Human beta-2 Microglobulin ELISA Kit for Sandwich ELISA - ABIN624946
Gejyo, Yamada, Odani, Nakagawa, Arakawa, Kunitomo, Kataoka, Suzuki, Hirasawa, Shirahama: A new form of amyloid protein associated with chronic hemodialysis was identified as beta 2-microglobulin. in Biochemical and biophysical research communications 1985
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Human beta-2 Microglobulin ELISA Kit for Sandwich ELISA - ABIN2683519
Trinh, Smith, Kalverda, Phillips, Radford: Crystal structure of monomeric human beta-2-microglobulin reveals clues to its amyloidogenic properties. in Proceedings of the National Academy of Sciences of the United States of America 2002
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Mouse (Murine) beta-2 Microglobulin ELISA Kit for Sandwich ELISA - ABIN2014324
Taylor, Zhang, Julander, Stoycheva, Tan, Moy, Chanda, Symons, Beigelman, Blatt, Hong: Development of a Hyperglycosylated IFN Alfacon-1 (CIFN): Toward Bimonthly or Monthly Dosing for Antiviral Therapies. in Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2015
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Rat (Rattus) beta-2 Microglobulin ELISA Kit for Sandwich ELISA - ABIN367427
Stockebrand, Hornig, Neu, Atzler, Cordts, Böger, Isbrandt, Schwedhelm, Choe: Homoarginine supplementation improves blood glucose in diet-induced obese mice. in Amino acids 2015
Dog (Canine) beta-2 Microglobulin ELISA Kit for Sandwich ELISA - ABIN577968
Palviainen, Raekallio, Vainionpää, Kosonen, Vainio: Proteomic profiling of dog urine after European adder (Vipera berus berus) envenomation by two-dimensional difference gel electrophoresis. in Toxicon : official journal of the International Society on Toxinology 2012
Rat (Rattus) beta-2 Microglobulin ELISA Kit for Sandwich ELISA - ABIN1874252
Ucibior, Go??biowska, Adamczyk, Nied?wiecka, Fornal: The renal effects of vanadate exposure: potential biomarkers and oxidative stress as a mechanism of functional renal disorders--preliminary studies. in BioMed research international 2014
Human beta-2 Microglobulin ELISA Kit for Sandwich ELISA - ABIN612797
Güssow, Rein, Ginjaar, Hochstenbach, Seemann, Kottman, Ploegh: The human beta 2-microglobulin gene. Primary structure and definition of the transcriptional unit. in Journal of immunology (Baltimore, Md. : 1950) 1987
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Serum B2M level was positively associated with Gensini score system, SYNTAX score system and the number of diseased coronary vessels.
Data suggest that T-cell receptor (TCR) alpha-constant domain (C- and F-strands) directly interacts with unbound MHC light chain, beta2-microglobulin (beta2M); these interactions do not appear to be involved in T-cell cytotoxicity, suggesting an alternate role for beta2M binding to TCR; TCR beta-chain does not appear to interact directly with beta2M.
High B2M levels were associated with an increased risk of ischemic stroke in this study of middle-aged women
Letter: serum levels of anti-carbonic anhydrase autoantibodies and beta macroglobulin correlate with ClinESSDAI score in patients with Sjogren's syndrome.
Beta2M mRNA expression in cells of the urinary sediment is higher in T1D patients with diabetic kidney disease and in patients with focal segmental glomerulosclerosis in comparison to healthy subjects, maybe reflecting a tubulointerstitial injury promoted by albumin (显示 ALB ELISA试剂盒).
Serum levels of beta trace protein and beta 2 microglobulin can be used to predict residual kidney function in hemodialysis patients.
The chaperone crystallin, which is a mild modulator of the lag (显示 STMN1 ELISA试剂盒) phase of the variant fibrillogenesis, potently inhibits fibril elongation of the wild-type even once it is absorbed on D76N beta2-microglobulin fibrils.
B2M is a potential tissue biomarker and therapeutic target of borderline and malignant ovarian tumours and the dysregulation of B2M in these tumours may be mediated by the TGF-beta (显示 TGFB1 ELISA试剂盒) signaling pathway.
BTP and B2M levels are less affected than serum by amputation, and should be considered for future study of GFR (显示 RAPGEF5 ELISA试剂盒) estimation
Overexpression of B2M are associated with invasion, metastasis of the pancreatic ductal adenocarcinoma.
The results show that, although other factors influence the fibril growth kinetics, a striking difference in the solubility of the proteins is a key determinant of the different amyloidogenicity of human B2M and mouse B2M.
Use of shRNA against beta-2-microglobulin offers a simple and effective approach to minimize immunogenicity of the main cellular components of cardiac tissue constructs in non-syngeneic recipients.
systemic B2M accumulation in aging blood promotes age-related cognitive dysfunction and impairs neurogenesis
Because all forms of H-2K(b) are internalized but little beta2m-receptive heavy chain is present at the cell surface, it is likely that beta2m dissociation and recognition of the heavy chain for lysosomal degradation take place in an endocytic compartment.
We report a novel dichotomous role of beta2m and CD1d, whereby these molecules differently regulate autoimmunity against phospholipid versus non-phospholipid autoantigens.
The goal of the present work was to study peculiarities in functioning of proteasomes and associated signaling pathways along with evaluation of NeuN (显示 RBFOX3 ELISA试剂盒) and gFAP (显示 GFAP ELISA试剂盒) expression in different sections of the brain in mice.
MHC I and b2m genes are both expressed in in human as well as mice during the developmental stages of cerebellar cortex
Knocking out beta 2 microglobulin abolishes NMDAR-dependent LTD in area CA1 of adult mouse hippocampus and is accompanied by memory deficits. MHC class I expression could be an unexpected cause of disrupted synaptic plasticity and cognitive deficits.
This study demonistrated that Deletion of beta-2-microglobulin ameliorates spinal cord lesion load and promotes recovery of brainstem NAA levels in a murine model of multiple sclerosis
Data show that tapasin (显示 TAPBP ELISA试剂盒) expression is enhanced by beta 2-microglobulin via both transcriptional and post-transcriptional mechanisms.
B2M contains alpha-helix, beta-sheet, turn, and random coil.
This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.
beta chain of MHC class I molecules
, beta-2-microglobulin C-terminal fragment (55 AA)
, beta 2-microglobulin
, beta-2 microglobulin
, beta 2 microglobulin
, beta-2-microglobulin-like protein
, beta2 microglobulin
, beta 2-m
, beta 2 microglobulin (54 AA)