anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) 抗体产品概述

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anti-SMAD, Mothers Against DPP Homolog 1 抗体 (SMAD1)
在www.antibodies-online.cn可供335 SMAD, Mothers Against DPP Homolog 1 (SMAD1) 抗体的30不同的供货商。 再加上,我们可以发SMAD, Mothers Against DPP Homolog 1 试剂盒 (54)SMAD, Mothers Against DPP Homolog 1 蛋白 (22)和数多这个蛋白质的别的产品。 总共430 SMAD, Mothers Against DPP Homolog 1产品已列进来了。
别名:
2/23, AI528653, apg, BSP-1, BSP1, c28, CG12399, dMad, Dmel\\CG12399, E(zen)2, En(vvl), fb39h09, JV4-1, JV41, l(2)k00237, mad, Madh1, Madr1, Mat, MLP, Mlp1, MusMLP, p-Mad, pMad, pSmad, Smad, smad-1, smad1, wu:fb39h09, wu:fb97e04, xmad, Xmad1, Xsmad1
列出全部抗体 基因 基因ID UniProt
SMAD1 4086 Q15797
SMAD1 17125 P70340
大鼠 SMAD1 SMAD1 25671  

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引用最多的anti-SMAD, Mothers Against DPP Homolog 1 抗体

  1. Human Monoclonal SMAD1 Primary Antibody for IF, WB - ABIN393492 : Jugessur, Shi, Gjessing, Lie, Wilcox, Weinberg, Christensen, Boyles, Daack-Hirsch, Nguyen, Christiansen, Lidral, Murray: Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. in PLoS ONE 2010 (PubMed)
    Show all 5 references for 393492

  2. Human Monoclonal SMAD1 Primary Antibody for IF, WB - ABIN393407 : Yang, Li, Al-Lamki, Southwood, Zhao, Lever, Grimminger, Schermuly, Morrell: Smad-dependent and smad-independent induction of id1 by prostacyclin analogues inhibits proliferation of pulmonary artery smooth muscle cells in vitro and in vivo. in Circulation research 2010 (PubMed)
    Show all 5 references for 393407

  3. Human Polyclonal SMAD1 Primary Antibody for WB - ABIN1881815 : Ye, Yu, Hu, Lu, Xie: Alterations of dendritic cell subsets in the peripheral circulation of patients with cervical carcinoma. in Journal of experimental & clinical cancer research : CR 2010 (PubMed)
    Show all 4 references for 1881815

  4. Human Polyclonal SMAD1 Primary Antibody for IF, WB - ABIN319351 : Li, Xin, Xu, Huang, Zhang, Chen, Zhang, Fu, Chang: CHIP mediates degradation of Smad proteins and potentially regulates Smad-induced transcription. in Molecular and cellular biology 2003 (PubMed)
    Show all 3 references for 319351

  5. Human Polyclonal SMAD1 Primary Antibody for ELISA, WB - ABIN1533926 : Liu, Hata, Baker, Doody, Cárcamo, Harland, Massagué: A human Mad protein acting as a BMP-regulated transcriptional activator. in Nature 1996 (PubMed)
    Show all 2 references for 1533926

  6. Human Polyclonal SMAD1 Primary Antibody for IHC, ELISA - ABIN1532214 : Hoodless, Haerry, Abdollah, Stapleton, OConnor, Attisano, Wrana: MADR1, a MAD-related protein that functions in BMP2 signaling pathways. in Cell 1996 (PubMed)
    Show all 2 references for 1532214

  7. Cow (Bovine) Polyclonal SMAD1 Primary Antibody for WB - ABIN2779411 : Blount, Merlie: BIP associates with newly synthesized subunits of the mouse muscle nicotinic receptor. in The Journal of cell biology 1991 (PubMed)
    Show all 2 references for 2779411

  8. Cow (Bovine) Polyclonal SMAD1 Primary Antibody for WB - ABIN2780720 : Jadlowiec, Zhang, Li, Campbell, Sfeir: Extracellular matrix-mediated signaling by dentin phosphophoryn involves activation of the Smad pathway independent of bone morphogenetic protein. in The Journal of biological chemistry 2006 (PubMed)

更多抗SMAD, Mothers Against DPP Homolog 1的相互作用对抗体

Zebrafish SMAD, Mothers Against DPP Homolog 1 (SMAD1) interaction partners

  1. Data show that interplay of Smad1/5 and MAP kinase (显示 MAPK1 抗体) signaling system (ERK (显示 MAPK1 抗体) signalling) is essential for haemogenic endothelium-based haematopoietic stem cell emergence.

  2. this study uncovers that smad1 and smad9 (显示 SMAD9 抗体) act redundantly to each other downstream of smad5 (显示 SMAD5 抗体) to mediate ventral specification and to regulate embryonic myelopoiesis.

  3. that specificity of BMP signaling output, with respect to hematopoiesis, can be explained by differential functions of Smad1 and Smad5 (显示 SMAD5 抗体).

Fruit Fly (Drosophila melanogaster) SMAD, Mothers Against DPP Homolog 1 (SMAD1) interaction partners

  1. This report provides a genetic analysis of primary nociceptive neuron mechanisms that promote sensitization in response to injury. Drosophila melanogaster larvae whose primary nociceptive neurons were reduced in levels of specific components of the BMP signaling pathway, were injured and then tested for nocifensive responses to a normally subnoxious stimulus.

  2. LTR sequence of the MDG4 (显示 MOD(MDG4) 抗体) retrotransposon contains the MAD protein (显示 MXD1 抗体) binding site that affects the east-dependent repression

  3. we identify key roles for the Zelda and Zerknullt transcription factors in establishing the resulting expression domain, and find widespread binding of insulator proteins to the Mad and Brinker-bound genomic regions. Analysis of embryos lacking the BEAF-32 insulator protein shows reduced transcription of a peak BMP target gene and a reduction in the number of amnioserosa cells, the fate specified by peak BMP signaling.

  4. Mad linker phosphorylations control the intensity and range of the BMP-activity gradient in developing Drosophila tissues.

  5. During development, synaptic pMad accumulation followed the arrival and clustering of ionotropic glutamate (显示 GRIN2A 抗体) receptors at neuromuscular junction synapses.

  6. The actions of Brat at synapses are mediated through mothers against decapentaplegic (Mad), the signal transduction effector of the bone morphogenetic protein (BMP) signaling pathway.

  7. Mad has distinct signal transduction roles in the BMP (显示 TGFb 抗体) and Wnt (显示 WNT4 抗体) pathways depending on its phosphorylation state.

  8. Yorkie (显示 YAP1 抗体) and Mad physically bind each other, and 410 bp minimal enhancer of bantam that responds to Yorkie:Mad in vivo and in cultured cells, was identified.

  9. Heterodimers of SAX and TKV play an important role in extending the BMP activity gradient by facilitating DPP diffusion and assisting GBB signaling through functional complexes with type II receptors.

  10. importin-beta11 function interacts with the bone morphogenic protein (显示 TGFb 抗体) pathway to regulate a pool of phosphorylated mothers against decapentaplegic that must be present at the presynapse for its proper development and function

Human SMAD, Mothers Against DPP Homolog 1 (SMAD1) interaction partners

  1. Store operated calcium entry negatively regulates the Smad1 (显示 GARS 抗体) signaling pathway and inhibits Col (显示 HDAC1 抗体) IV protein production in glomerular mesangial cells.

  2. A significant association was found between the low expression of inhibitory protein SMAD-7 (显示 SMAD7 抗体) and both zeta-chain-associated protein kinase (显示 CDK7 抗体) 70-negative cells (p = 0.04) and lower apoptotic index (p = 0.004). No differences were observed in SMAD-2 (显示 SMAD2 抗体)/3 expression. In conclusion, our results demonstrate a significant correlation between greater SMAD-1 (显示 GARS 抗体)/8 and lower SMAD-4 (显示 SMAD4 抗体) expression in chronic lymphocytic leukemia cells

  3. melatonin treatment was found to downregulate TNFalpha (显示 TNF 抗体)-induced SMURF1 (显示 SMURF1 抗体) expression and then decrease SMURF1 (显示 SMURF1 抗体)-mediated ubiquitination and degradation of SMAD1 (显示 GARS 抗体) protein

  4. The expression of specific targets Smad1 (显示 GARS 抗体) and Osterix (显示 SP7 抗体) was significantly increased in the presence of Pi and restored by coincubation with Mg(2 (显示 MUC7 抗体)+). As miR (显示 MLXIP 抗体)-30b, miR (显示 MLXIP 抗体)-133a, and miR (显示 MLXIP 抗体)-143 are negatively regulated by Pi and restored by Mg(2 (显示 MUC7 抗体)+) with a congruent modulation of their known targets Runx2 (显示 RUNX2 抗体), Smad1 (显示 GARS 抗体), and Osterix (显示 SP7 抗体), our results provide a potential mechanistic explanation of the observed upregulation of these master switches of o

  5. the BMP-2 (显示 BMP2 抗体)/Smad1 (显示 GARS 抗体)/5/RUNX2 (显示 RUNX2 抗体) signaling pathway participates in the silicon-mediated induction of COL-1 and osteocalcin (显示 BGLAP 抗体) synth

  6. Regulation of impaired angiogenesis in diabetic dermal wound healing by microRNA-26a is mediated by the increased expression of its target gene, SMAD1 (显示 GARS 抗体).

  7. The expression SMAD1 (显示 GARS 抗体) protein showed a significant correlation with lung cancer differentiation and lymphatic metastasis (P < 0.05), but not with genders, ages, tumor sizes and histological types of lung cancer patients (P>0.05).

  8. Overexpression of Smad1 (显示 GARS 抗体) is associated with prostate cancer.

  9. SMAD1 (显示 GARS 抗体) signaling may be a key pathway contributing the pathogenesis of Cardio-facio-cutaneous syndrome during early development.

  10. Smad1 (显示 GARS 抗体) elevation serves as a compensatory mechanism for p53 (显示 TP53 抗体) deficiency by potentiating the activation of p53 (显示 TP53 抗体) parallel pathways.

Mouse (Murine) SMAD, Mothers Against DPP Homolog 1 (SMAD1) interaction partners

  1. these studies characterize an accessory TGF-beta (显示 TGFB1 抗体)-stimulated BMP R-Smad signaling mechanism in interstitial cells of the developing lung.

  2. these results identify a novel function of YAP (显示 YAP1 抗体) in neocortical astrocytic differentiation and proliferation, and reveal a BMP2 (显示 BMP2 抗体)-YAP (显示 YAP1 抗体)-SMAD1 pathway underlying astrocytic differentiation in the developing mouse neocortex.

  3. Dynamin (显示 DNM1 抗体)-dependent endocytosis of Bone Morphogenetic Protein2 (BMP2 (显示 BMP2 抗体)) and its receptors is dispensable for the initiation of Smad signaling

  4. Thyroid-specific Smad1 and Smad5 (显示 SMAD5 抗体) double-knockout (Smad1/5(dKO)) mice displayed growth retardation, hypothyroidism and defective follicular architecture.

  5. Smad1 and Smad5 (显示 SMAD5 抗体) have overlapping functions to govern hepcidin (显示 HAMP 抗体) transcription. Moreover, erythropoietin (显示 EPO 抗体) and erythroferrone target Smad1/5 signaling and require Smad1/5 to suppress hepcidin (显示 HAMP 抗体) expression.

  6. Actin cytoskeleton depolymerization inhibites BMP2 (显示 BMP2 抗体) signaling via blocking of Smad by dephosphorylated CNN1 (显示 CNN1 抗体) in osteoblast cells under simulated microgravity.

  7. Store operated calcium entry negatively regulates the Smad1 signaling pathway and inhibits Col (显示 HDAC1 抗体) IV protein production in glomerular mesangial cells.

  8. Thus, our findings identify an unrecognized function of neogenin (显示 NEO1 抗体) in mouse neocortical astrocyte differentiation, and suggest a signaling pathway, BMP2 (显示 BMP2 抗体)-neogenin (显示 NEO1 抗体)-YAP (显示 YAP1 抗体)-Smad1, underlying astrogliogenesis in developing mouse neocortex.

  9. Collectively, the data suggest that Cytl1 (显示 CYTL1 抗体) plays an essential role in cardiac fibrosis likely through activating the TGF-beta (显示 TGFB1 抗体)-SMAD signaling pathway.

  10. BetA can enhance in vivo osteogenic potentials of BMP2 (显示 BMP2 抗体), possibly via stimulating Smad 1/5/8 and p38 (显示 CRK 抗体) pathways, and combination of both agents can be considered as a therapeutic strategy for bone diseases.

Xenopus laevis SMAD, Mothers Against DPP Homolog 1 (SMAD1) interaction partners

  1. interactions between miR (显示 MYLIP 抗体)-26 and the Smad1 3'UTR (显示 UTS2R 抗体) modulate Smad1 function in the establishment of axial patterning.

Cow (Bovine) SMAD, Mothers Against DPP Homolog 1 (SMAD1) interaction partners

  1. a detailed computational model for TGF-beta (显示 TGFB1 抗体) signalling that incorporates elements of previous models together with crosstalking between Smad1/5/8 and Smad2 (显示 SMAD2 抗体)/3 channels through a negative feedback loop dependent on Smad7 (显示 SMAD7 抗体).

SMAD, Mothers Against DPP Homolog 1 (SMAD1) 抗原简介

Antigen Summary

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed.

Alternative names and synonyms associated with SMAD, Mothers Against DPP Homolog 1 (SMAD1)

  • SMAD family member 1 (smad1) 抗体
  • SMAD family member 1 (SMAD1) 抗体
  • MAD homolog 1 (Drosophila) (smad1) 抗体
  • Mothers against dpp (Mad) 抗体
  • SMAD family member 1 (Smad1) 抗体
  • SMAD family member 1 (smad1-a) 抗体
  • 2/23 抗体
  • AI528653 抗体
  • apg 抗体
  • BSP-1 抗体
  • BSP1 抗体
  • c28 抗体
  • CG12399 抗体
  • dMad 抗体
  • Dmel\\CG12399 抗体
  • E(zen)2 抗体
  • En(vvl) 抗体
  • fb39h09 抗体
  • JV4-1 抗体
  • JV41 抗体
  • l(2)k00237 抗体
  • mad 抗体
  • Madh1 抗体
  • Madr1 抗体
  • Mat 抗体
  • MLP 抗体
  • Mlp1 抗体
  • MusMLP 抗体
  • p-Mad 抗体
  • pMad 抗体
  • pSmad 抗体
  • Smad 抗体
  • smad-1 抗体
  • smad1 抗体
  • wu:fb39h09 抗体
  • wu:fb97e04 抗体
  • xmad 抗体
  • Xmad1 抗体
  • Xsmad1 抗体

Protein level used designations for SMAD1

MAD homolog 1 , SMAD, mothers against DPP homolog 1 , mothers against decapentaplegic homolog 1 , mothers against decapentaplegic-like protein 1 , MAD (mothers against decapentaplegic, Drosophila) homolog 1 , SMA- and MAD-related protein 1 , SMAD 1 , SMAD family member 1 , mothers against DPP homolog 1 , CG12399-PA , CG12399-PB , Mad-PA , Mad-PB , apang , mother against decapentaplegic , mothers against decapentaplegi , mothers against decapentaplegic , mothers against dpp , phospho-Smad , phosphoSmad , phosphorylated smad , MAD, mothers against decapentaplegic homolog 1 , Mad-related protein 1 , TGF-beta signaling protein 1 , transforming growth factor-beta signaling protein 1 , transforming growth factor-beta-signaling protein 1 , Smad 1 , dwarfin-A , dwf-A , mMad1 , mad-related protein 1 , mothers-against-DPP-related 1 , MAD homolog1 (mothers against decapentaplegic, Drosophila) , mothers against DPP , BMP pathway effector , BMP signal transducer Smad1 , Sma- and Mad-related protein 1

GENE ID SPECIES
493211 Xenopus (Silurana) tropicalis
574340 Macaca mulatta
30628 Danio rerio
33529 Drosophila melanogaster
4086 Homo sapiens
17125 Mus musculus
25671 Rattus norvegicus
379664 Xenopus laevis
395680 Gallus gallus
475456 Canis lupus familiaris
397016 Sus scrofa
540488 Bos taurus
450142 Pan troglodytes
100432108 Pongo abelii
100033850 Equus caballus
443229 Ovis aries
100341544 Oryctolagus cuniculus
100727257 Cavia porcellus
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