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抗Human RAB5 抗体:
抗Mouse (Murine) RAB5 抗体:
抗Rat (Rattus) RAB5 抗体:
Human Polyclonal RAB5 Primary Antibody for ICC, IF - ABIN266020
Sönnichsen, De Renzis, Nielsen, Rietdorf, Zerial: Distinct membrane domains on endosomes in the recycling pathway visualized by multicolor imaging of Rab4, Rab5, and Rab11. in The Journal of cell biology 2000
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Human Monoclonal RAB5 Primary Antibody for IF, IP - ABIN967882
Huang, Imamura, Olefsky: Insulin can regulate GLUT4 internalization by signaling to Rab5 and the motor protein dynein. in Proceedings of the National Academy of Sciences of the United States of America 2001
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Human Monoclonal RAB5 Primary Antibody for IF, IP - ABIN967881
Li, Stahl: Structure-function relationship of the small GTPase rab5. in The Journal of biological chemistry 1993
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Dog (Canine) Monoclonal RAB5 Primary Antibody for IF, IHC - ABIN968139
Sanford, Pan, Wessling-Resnick: Prenylation of Rab5 is dependent on guanine nucleotide binding. in The Journal of biological chemistry 1993
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Dog (Canine) Monoclonal RAB5 Primary Antibody for IF, IHC - ABIN968138
Stenmark, Vitale, Ullrich, Zerial: Rabaptin-5 is a direct effector of the small GTPase Rab5 in endocytic membrane fusion. in Cell 1996
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Cow (Bovine) Polyclonal RAB5 Primary Antibody for ICC, IF - ABIN361846
Ali, Wasmeier, Lamoreux, Strom, Seabra: Multiple regions contribute to membrane targeting of Rab GTPases. in Journal of cell science 2004
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Human Monoclonal RAB5 Primary Antibody for ELISA, WB - ABIN519585
Chamberlain, Oberg, Furber, Poland, Hawrysh, Knafelc, McBride, Anderson: Deregulation of Rab5 and Rab4 proteins in p85R274A-expressing cells alters PDGFR trafficking. in Cellular signalling 2010
Mouse (Murine) Polyclonal RAB5 Primary Antibody for ICC, IF - ABIN447323
Ramakrishnan, Tyurin, Tuyrin, Veglia, Condamine, Amoscato, Mohammadyani, Johnson, Zhang, Klein-Seetharaman, Celis, Kagan, Gabrilovich: Oxidized lipids block antigen cross-presentation by dendritic cells in cancer. in Journal of immunology (Baltimore, Md. : 1950) 2014
Cow (Bovine) Polyclonal RAB5 Primary Antibody for IHC, WB - ABIN2786773
Coyne, Shen, Turner, Bergelson: Coxsackievirus entry across epithelial tight junctions requires occludin and the small GTPases Rab34 and Rab5. in Cell host & microbe 2007
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Human Polyclonal RAB5 Primary Antibody for IP, WB - ABIN1742215
Perlini, Botti, Fornasiero, Giannandrea, Bonanomi, Amendola, Naldini, Benfenati, Valtorta: Effects of phosphorylation and neuronal activity on the control of synapse formation by synapsin I. in Journal of cell science 2011
Membrane localization and dynamics of geranylgeranylated Rab5 hypervariable region has been reported.
study elucidated a novel Malat1-miR-101-STMN1/RAB5A/ATG4D regulatory network that Malat1 activates autophagy and promotes cell proliferation by sponging miR-101 and upregulating STMN1, RAB5A and ATG4D expression in glioma cells
In conclusion, mutant KRAS promotes endosomal degradation in PDAC cell lines, which is impaired by KRAS silencing. Moreover, KRAS silencing activates RAB5A upregulation and drives PDAC subtype-dependent modulation of endosome trafficking.
siRNA knockdown of Rab5a or overexpression of miR (显示 MLXIP 抗体)-494 in human macrophages significantly inhibits the survival of the parasites
our results show that Rab5a is overexpressed in pancreatic cancer and promotes aggressive biological behavior through regulation of the Wnt (显示 WNT2 抗体)/beta-catenin (显示 CTNNB1 抗体) signaling pathway.
CMTM3 (显示 CMTM3 抗体) decreases EGFR (显示 EGFR 抗体) expression, facilitates EGFR (显示 EGFR 抗体) degradation, and inhibits the EGF (显示 EGF 抗体)-mediated tumorigenicity of gastric cancer cells by enhancing Rab5 activity.
High RAS-associated protein (显示 RGL2 抗体) RAB5 expression correlated with the presence of lymphatic invasion and venous invasion and low E-cadherin (显示 CDH1 抗体) expression.
downregulated Rab5a led to slowed cell growth, decreased numbers of migrated cells, decreased numbers of cells at the G0G1 phase and a higher apoptosis rate. However, PDGF (显示 PDGFA 抗体) significantly rescued these phenomena caused by siRNA against Rab5a
results suggest a new mechanism in which Rab5 induces a change in flexibility of EEA1 (显示 EEA1 抗体), generating an entropic collapse force that pulls the captured vesicle towards the target membrane to initiate docking and membrane fusion
structural differences may provide an opportunity to selectively target one Rab5 state and lead to new approaches in the development of Rab5-specific therapies
SH3GLB1 (显示 SH3GLB1 抗体) controls nicotinic acetylcholine receptors endocytic trafficking in a phosphorylation- and RAB5-dependent manner at steps upstream of autophagosome formation.
E. chaffeensis secretes Etf-1 (显示 ETF1 抗体) to induce autophagy to repurpose the host cytoplasm and capture nutrients for its growth through RAB5 and class III PtdIns3K, while avoiding autolysosomal killing.
These data highlight a requirement of Rab5 and the endosomal system for the regulation of gluconeogenic gene expression that has important implications for metabolic diseases.
Inpp5e (显示 INPP5E 抗体), through functional interactions with Rab20 (显示 RAB20 抗体) on the phagosome, activates Rab5, which, in turn, increases PtdIns3P and delays phagosome acidification.
FGF21 (显示 FGF21 抗体) has a role in promoting endothelial cell angiogenesis through a dynamin-2 (显示 DNM2 抗体) and Rab5 dependent pathway
In silico screening for palmitoyl substrates reveals a role for DHHC1/3/10 (zDHHC1/3/11)-mediated neurochondrin (显示 NCDN 抗体) palmitoylation in its targeting to Rab5-positive endosomes.
In mammalian cells, p110beta acts as a molecular sensor for growth factor availability and induces autophagy by activating a Rab5-mediated signaling cascade.
Data show that Rinl is closely associated with the cytoskeleton and thus contributes to the spatial control of Rab5a and Rab22 signaling at actin-positive compartments.
Data reveal the affinity of Rabex-5 (显示 RABGEF1 抗体)/Rabaptin-5 (显示 RABEP1 抗体)/Rab5-GTP (显示 AK3 抗体) interaction in the cell, which is quantitatively related to the Rabex-5 (显示 RABGEF1 抗体) concentration for the onset of the indirect
Rab5 regulates and coordinates different endocytic mechanisms through its effector Rabankyrin-5 (显示 ANKFY1 抗体)
Expression of dominant negative Rab5 and Rab7 (显示 RAB7A 抗体) mutants, but not the dominant negative Rab11 (显示 RAB11A 抗体) mutant, significantly inhibited classical swine fever virus replication. These results were confirmed by silencing of Rab5 and Rab7 (显示 RAB7A 抗体).
Dominant-negative mutant rab5 inhibits FMDV infection of IBRS-2 cells.
Required for the fusion of plasma membranes and early endosomes (By similarity).
, Rab5a, GTPase
, hypothetical protein
, Ras-related protein Rab-5A
, ras-related protein rab-5a
, RAB5A, member RAS oncogene family
, ras-related protein Rab-5A
, RAS-associated protein RAB5A
, small GTP-binding protein rab5
, GTP-binding protein (rab5)