anti-VEGFC (VEGFC) 抗体产品概述

Full name:
anti-Vascular Endothelial Growth Factor C 抗体 (VEGFC)
在www.antibodies-online.cn可供301 Vascular Endothelial Growth Factor C (VEGFC) 抗体的26不同的供货商。 再加上,我们可以发VEGFC 蛋白 (84)VEGFC 试剂盒 (66)和数多这个蛋白质的别的产品。 总共458 VEGFC产品已列进来了。
别名:
AW228853, Flt4-L, VEGF-C, VEGFC, VRP, xvegf-c

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抗Human VEGFC 抗体:

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引用最多的anti-VEGFC 抗体

  1. Human Polyclonal VEGFC Primary Antibody for IHC (fro), IHC (p) - ABIN258871 : Zampell, Yan, Avraham, Daluvoy, Weitman, Mehrara: HIF-1α coordinates lymphangiogenesis during wound healing and in response to inflammation. in FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2012 (PubMed)
    Show all 8 references for 258871

  2. Human Polyclonal VEGFC Primary Antibody for EIA, IHC (p) - ABIN357425 : Byeon, Jung, Lee, Lee, Lee, Myung, Yang, Hong, Kim, Min, Kim: Clinicopathological significance of vascular endothelial growth factor-C and cyclooxygenase-2 in esophageal squamous cell carcinoma. in Journal of gastroenterology and hepatology 2004 (PubMed)
    Show all 5 references for 357425

  3. Human Polyclonal VEGFC Primary Antibody for FACS, IHC (p) - ABIN650694 : Yan, Zhu, Yu, Ji, Zhang, Ji, Yan, Chen, Liu, Yin, Lin: Expression of vascular endothelial growth factor C and chemokine receptor CCR7 in gastric carcinoma and their values in predicting lymph node metastasis. in World journal of gastroenterology : WJG 2004 (PubMed)
    Show all 3 references for 650694

  4. Human Monoclonal VEGFC Primary Antibody for WB - ABIN659094 : Chen, Xie, Cheng, Diao, Cheng, Liu, Xie, Chen, Zhu: Role of interleukin-17 in lymphangiogenesis in non-small-cell lung cancer: Enhanced production of vascular endothelial growth factor C in non-small-cell lung carcinoma cells. in Cancer science 2010 (PubMed)
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  5. Human Monoclonal VEGFC Primary Antibody for ICC, IHC (fro) - ABIN438679 : Moussai, Mitsui, Pettersen, Pierson, Shah, Suárez-Fariñas, Cardinale, Bluth, Krueger, Carucci: The human cutaneous squamous cell carcinoma microenvironment is characterized by increased lymphatic density and enhanced expression of macrophage-derived VEGF-C. in The Journal of investigative dermatology 2010 (PubMed)
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  6. Human Polyclonal VEGFC Primary Antibody for EIA, FACS - ABIN955510 : Deguchi, Ichikawa, Soga, Watanabe, Kosuga, Takeshita, Konishi, Morimura, Tsujiura, Komatsu, Shiozaki, Okamoto, Fujiwara, Otsuji: Clinical significance of vascular endothelial growth factors C and D and chemokine receptor CCR7 in gastric cancer. in Anticancer research 2010 (PubMed)
    Show all 2 references for 955510

  7. Human Monoclonal VEGFC Primary Antibody for EIA, WB - ABIN360868 : Olofsson, Jeltsch, Eriksson, Alitalo: Current biology of VEGF-B and VEGF-C. in Current opinion in biotechnology 2000 (PubMed)
    Show all 2 references for 360868

  8. Human Monoclonal VEGFC Primary Antibody for WB - ABIN659093 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)
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更多抗VEGFC的相互作用对抗体

Zebrafish Vascular Endothelial Growth Factor C (VEGFC) interaction partners

  1. Vegfc acts through ERK (显示 MAPK1 抗体) to induce sprouting and differentiation of trunk lymphatic progenitors.

  2. data not only reveal a non-canonical function of Mt2 (显示 MT2 抗体) in angiogenesis, but also propose Mt2 (显示 MT2 抗体) as a novel regulator of vegfc expression.

  3. Vegfc signaling increases mafba (显示 MAFB 抗体) expression to control downstream transcription

  4. Vegfc is dispensable for facial lymphatic sprouting but not for the complete development of the facial lymphatic network.

  5. In the embryo, phenotypes driven by increased Vegfc are suppressed in the absence of Ccbe1 (显示 CCBE1 抗体), and Vegfc-driven sprouting is enhanced by local Ccbe1 (显示 CCBE1 抗体) overexpression. Moreover, Vegfc- and Vegfr3 (显示 FLT4 抗体)-dependent Erk (显示 MAPK1 抗体) signaling is impaired in the absence of Ccbe1 (显示 CCBE1 抗体).

  6. Vegfc has an essential role in lymphangiogenesis [review]

  7. The parallel growth of motoneuron axons with the dorsal aorta depends on Vegfc/Vegfr3 (显示 FLT4 抗体) signaling in zebrafish.

  8. Vegfc acts in two distinct modes during development: as a paracrine factor secreted from arteries to guide closely associated lymphatic vasculature and as an autocrine factor to drive migratory persistence during angiogenesis.

  9. Rspo1-Wnt-VegfC-Vegfr3 signaling plays a crucial role as an endothelial-autonomous permissive cue for developmental angiogenesis.

  10. Here, we show that vascular endothelial growth factor C (Vegfc), an angiogenic as well as a lymphangiogenic factor, is unexpectedly involved in this process in zebrafish.

Pig (Porcine) Vascular Endothelial Growth Factor C (VEGFC) interaction partners

  1. VEGF-C and VEGF-C156S genes have roles in the pro-lymphangiogenic growth factor therapy of lymphedema

  2. Transcription of the vascular endothelial growth factor C gene (VEGF-C) and translation of the corresponding protein were significantly up-regulated in swine umbilical vein endothelial cells with classical swine fever virus acute infection.

  3. No difference in bioactivity was detected between porcine relaxin-1 (显示 RLN1 抗体) and recombinant human relaxin-2 (显示 RLN1 抗体) in either mice or rats.

  4. During progressive ischemia, functional and metabolic benefits of intramyocardial VEGF-C gene transfer were apparent. VEGF-C-induced collateral formation occurred at the site of gene transfer

Human Vascular Endothelial Growth Factor C (VEGFC) interaction partners

  1. Data show that VEGF-C, VEGF-D (显示 Figf 抗体), and VEGFR-3 (显示 FLT4 抗体) were expressed in a substantial percentage of breast carcinomas.

  2. By treating LECs with VEGF (显示 VEGFA 抗体)-C156S and analyzing subsequent changes in gene expression, we identified several 'immediate early (显示 JUN 抗体)' transcription factors that showed a rapid transient upregulation VEGFR-3 (显示 FLT4 抗体) stimulation. these results reveal an important and unanticipated role of HOXD10 (显示 HOXD10 抗体) in the regulation of VEGFR-3 (显示 FLT4 抗体) signaling in lymphatic endothelial cells, and in the control of lymphangiogenesis and permeability.

  3. In colon cancer samples, there was a positive correlation between the expression of integrin alpha4 and VEGF-C. Integrin alpha4 and VEGF-C were significantly associated with the clinicopathological parameters (LMVD, Duke's stage, and lymph node metastasis). patients with high integrin alpha4 or VEGF-C expression had significantly shorter overall survival and tumor-free survival time.

  4. High VEGFC expression is associated with angiogenesis and lymphangiogenesis.

  5. Adiponectin (显示 ADIPOQ 抗体) promoted VEGF-C expression and secretion in human chondrosarcoma cells.

  6. HuR (显示 ELAVL1 抗体) plays important roles in determining malignant aggressiveness and outcome in prostate cancer (PCa (显示 FLVCR1 抗体)), especially in androgen-independent PCa (显示 FLVCR1 抗体) cells, via the regulation of cell proliferation, migration, and expression of VEGF-A (显示 VEGFA 抗体), -C, and COX-2 (显示 COX2 抗体).

  7. Study showed that VEGF-C levels are high in hypervolemic and low in euvolemic (and hypovolemic) chronic kidney disease patients; serum VEGF-C levels were significantly correlated with bioimpedance spectroscopy measurements

  8. Taken together, we suggest that ELK3 (显示 ELK3 抗体) is an upstream regulator of the NF-kappaB (显示 NFKB1 抗体) signaling pathway, the inhibition of which leads to the suppression of peritumoral lymphatic vessel development, possibly due to a low VEGFC expression.

  9. These results indicate that VEGF-C-induced MSC (显示 MSC 抗体) osteogenesis is mediated through VEGFR2 (显示 KDR 抗体) and VEGFR3 (显示 FLT4 抗体), and followed the activation of the ERK (显示 EPHB2 抗体)/RUNX2 (显示 RUNX2 抗体) signaling pathway.

  10. Overexpression of vascular endothelial growth factor C (VEGF-C) in Kazakh esophageal squamous cell carcinoma (ESCC) was significantly associated with gender, depth of tumor invasion, lymph node metastasis and tumor clinical stage.

Mouse (Murine) Vascular Endothelial Growth Factor C (VEGFC) interaction partners

  1. lymphangiogenesis is regulated by two distinct proteolytic mechanisms of ligand activation: one in which VEGFC activation by ADAMTS3 (显示 Adamts2 抗体) and CCBE1 (显示 CCBE1 抗体) spatially and temporally patterns developing lymphatics, and one in which VEGFD (显示 Figf 抗体) activation by a distinct proteolytic mechanism may be stimulated during inflammatory lymphatic growth

  2. These results reveal an unexpected role for VEGF-C, a major lymphangiogenic growth factor, in the transition to fetal liver erythropoiesis.

  3. Results suggest that interleukin-6 (IL-6 (显示 IL6 抗体)) increases VEGF-C induction and lymphangiogenesis may involve, at least in part, Src (显示 SRC 抗体)-FAK (显示 PTK2 抗体)-STAT3 (显示 STAT3 抗体) cascade in lymphatic endothelial cells (LECs).

  4. Data show that heparanase-1 (HPA-1 (显示 HPSE 抗体)) induced shedding of heparan sulfate chain from syndecan-1 (SDC-1 (显示 SDC1 抗体)) facilitated the release of vascular endothelial growth factor C (VEGF-C) from SDC-1 (显示 SDC1 抗体)/VEGF-C complex into the medium of hepatocarcinoma cell.

  5. Data show that in the MCF-7 breast cancer cell line, only MT1X (显示 MT1X 抗体) metallothioneins (MTs (显示 NEU2 抗体)) positively correlated with vascular endothelial growth factor C (VEGFC).

  6. The findings in this study strongly suggest the following: i) that VEGF-C promotes the proliferative activity and migratory ability of mesenchymal stem cell ; and ii) VEGF-C and Tgfb (显示 TGFB1 抗体) reciprocally regulate mesenchymal stem cell commitment to differentiation into lymphatic endothelial or osteoblastic phenotypes, respectively.

  7. The authors show that VEGF-C is necessary for perinatal lymphangiogenesis, but required for adult lymphatic vessel maintenance only in the intestine.

  8. MT1-MMP (显示 MMP14 抗体) directly cleaves LYVE-1 (显示 LYVE1 抗体) on lymphatic endothelial cells to inhibit LYVE-1 (显示 LYVE1 抗体)-mediated lymphangiogenic responses and restrains the production of VEGF-C.

  9. HA increases lymphangiogenesis in renal fibrosis model and also stimulates vascular endothelial cell growth factor (显示 FGF1 抗体)-C production from macrophages through Toll-like receptor 4 (显示 TLR4 抗体)-dependent signal pathway

  10. Results showed that the VEGF-C/VEGFR-3 (显示 FLT4 抗体) system underlies the protective effect of ischemic preconditioning against forebrain ischemia in the mouse hippocampus

VEGFC 抗原简介

Antigen Summary

The protein encoded by this gene is a member of the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family, is active in angiogenesis and endothelial cell growth, and can also affect the permeability of blood vessels. This secreted protein undergoes a complex proteolytic maturation, generating multiple processed forms which bind and activate VEGFR-3 receptors. Only the fully processed form can bind and activate VEGFR-2 receptors. This protein is structurally and functionally similar to vascular endothelial growth factor D.

Alternative names and synonyms associated with VEGFC

  • vascular endothelial growth factor c (vegfc) 抗体
  • vascular endothelial growth factor C (VEGFC) 抗体
  • vascular endothelial growth factor C (vegfc) 抗体
  • vascular endothelial growth factor C (Vegfc) 抗体
  • vascular endothelial growth factor C-like (LOC100525960) 抗体
  • AW228853 抗体
  • Flt4-L 抗体
  • VEGF-C 抗体
  • VEGFC 抗体
  • VRP 抗体
  • xvegf-c 抗体

Protein level used designations for VEGFC

vascular endothelial growth factor C , vascular endothelial growth factor c , FLT4 ligand DHM , VEGF-C , vascular endothelial growth factor-related protein , VRP , flt4 ligand , flt4-L , vascular endothelial growth factor C isoform 129 , vascular endothelial growth factor C isoform 184

GENE ID SPECIES
403049 Danio rerio
699502 Macaca mulatta
100380462 Salmo salar
734331 Xenopus laevis
100127470 Sus scrofa
7424 Homo sapiens
22341 Mus musculus
114111 Rattus norvegicus
100338211 Oryctolagus cuniculus
100724469 Cavia porcellus
282122 Bos taurus
482932 Canis lupus familiaris
422573 Gallus gallus
101105629 Ovis aries
100525960 Sus scrofa
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