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Human Angiopoietin 1 ELISA Kit for Sandwich ELISA - ABIN624939
Khan, Sharma, Kumar, Husain, Sharma: Interrelationship and expression profiling of cyclooxygenase and angiogenic factors in Indian patients with multiple myeloma. in Annals of hematology 2013
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Human Angiopoietin 1 ELISA Kit for Sandwich ELISA - ABIN414353
Retzlaff, Thamm, Ghosh, Ziegler, Haller, Parikh, David: Flunarizine suppresses endothelial Angiopoietin-2 in a calcium - dependent fashion in sepsis. in Scientific reports 2017
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Mouse (Murine) Angiopoietin 1 ELISA Kit for Sandwich ELISA - ABIN415585
Nakamura, Suzuki, Shimizu, Miyata, Shishido, Ikeda, Saitoh, Kubota, Takeishi: High Mobility Group Box 1 Promotes Angiogenesis from Bone Marrow-derived Endothelial Progenitor Cells after Myocardial Infarction. in Journal of atherosclerosis and thrombosis 2015
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Rat (Rattus) Angiopoietin 1 ELISA Kit for Sandwich ELISA - ABIN365582
Koyama, Maebara, Hayashi, Nagae, Tokuyama, Michinaga: Endothelins reciprocally regulate VEGF-A and angiopoietin-1 production in cultured rat astrocytes: implications on astrocytic proliferation. in Glia 2012
Mouse (Murine) Angiopoietin 1 ELISA Kit for Sandwich ELISA - ABIN2683441
Bi, Niu, Ding, Zhang, Yang, Gu: Angiopoietin-1 attenuates angiotensin II-induced ER stress in glomerular endothelial cells via a Tie2 receptor/ERK1/2-p38 MAPK-dependent mechanism. in Molecular and cellular endocrinology 2016
Zebra fish (Danio rerio) morphants showed that mild knock down of Ang-1 produces a small-brained phenotype that could be rescued with Ang-1 mRNA.
These results indicate that the Angpt-Tie2 (显示 TEK ELISA试剂盒) system is essential for SC integrity. The impairment of this system underlies POAG-associated pathogenesis, supporting the possibility that Tie2 (显示 TEK ELISA试剂盒) agonists could be a therapeutic option for glaucoma.
we demonstrate that targeted Ang-1 overexpression attenuates myofibroblast activation and interstitial collagen I accumulation, inhibits the upregulation of transforming growth factor beta1 and subsequent phosphorylation of Smad 2 (显示 SMAD2 ELISA试剂盒)/3, dampens renal inflammation, and stimulates the growth of peritubular capillaries in the obstructed kidney.
Hydroxysafflor yellow A promotes angiogenesis in ischemic hindlimb via the angiopoietin 1/ (显示 TEK ELISA试剂盒) Tie-2 signaling pathway.
COMP (显示 COMP ELISA试剂盒)-Ang1 can enhance BMP2 (显示 BMP2 ELISA试剂盒)-induced cranial bone regeneration with increased pericyte recruitment. Combined delivery of the proteins might be a therapeutic strategy to repair cranial bone damage.
Hematopoietic stem cells regulate the regeneration of their niche by secreting Angpt1.
Myocardium-derived angiopoietin-1 is essential for coronary vein formation in the developing heart.
Ang-1 strongly enhances skeletal muscle regeneration in response to fiber injury and that this effect is mediated through induction of the myogenesis program in muscle progenitor cells and the angiogenesis program in endothelial cells.
These results suggest that PRP extract prevents endotoxin-induced pulmonary edema mainly through Ang (显示 ANG ELISA试剂盒)-Tie2 (显示 TEK ELISA试剂盒) signaling, and PRP extract could be a potential therapeutic strategy for sepsis-induced pulmonary edema
E2 increases Ang-1 and enhances capillary density in brain under basal conditions through estrogen receptor-alpha (显示 ESR1 ELISA试剂盒), priming the middle cerebral artery territory for survival after experimental focal ischemia
The important role of Ang-1 in the activation of mast cells, and a potential therapeutic effect of Ang-1 on anaphylaxis diseases.
Ang-1 specifically increases circulating Gr1(+ )inflammatory monocytes and increases monocyte/macrophage retention in atherosclerotic plaques, thereby contributing to development of atherosclerosis.
NOX2 (显示 CYBB ELISA试剂盒), NOX4 (显示 NOX4 ELISA试剂盒), and mitochondrial-derived reactive oxygen species contribute to angiopoietin-1 signaling and angiogenic responses in endothelial cells.
ANG-1, ANG-2 (显示 ANGPT2 ELISA试剂盒) and TIE-2 (显示 TEK ELISA试剂盒) levels were significantly increased in placenta of non-complicated ART pregnancies compared to placentas from spontaneous conception.
study is the first one to report Ang1 capacity to induce MIP-1beta (显示 CCL4 ELISA试剂盒) gene expression, protein synthesis and release from neutrophils, and that these effects are mediated by PI3K (显示 PIK3CA ELISA试剂盒), p38 MAPK (显示 MAPK14 ELISA试剂盒) and MEK (显示 MAP2K1 ELISA试剂盒) activation and downstream NF-kappaB (显示 NFKB1 ELISA试剂盒) activation
In this study, we found that angiopoietins and Tie receptors were highly expressed in cervical cancer cells. Tie-2 (显示 TEK ELISA试剂盒) expression in tumor cells predicted poorer prognosis.Our data support that dual inhibition of Ang-1 and Ang-2 (显示 ANGPT2 ELISA试剂盒) may be an alternative target for anti-angiogenic adjuvant therapy in advanced or recurrent cervical squamous cell cancer.
Data show that fibulin-5 (显示 FBLN5 ELISA试剂盒) strongly binds to the endothelial cell surface reducing endothelial cell viability and interfering with the signaling pathways of the Ang-1/TIE-2 (显示 TEK ELISA试剂盒) receptor axis.
Ang-1 is not a predictive and clinically relevant biomarker in pulmonary hypertension
We could therefore conclude that angiogenesis is an important event in the development of common skin warts, and the upregulation of both Ang1 and -2 and their binding receptor Tie2 (显示 TEK ELISA试剂盒) may play a role in the angiogenesis associated with the development of these lesions.
In vitro binding assays with purified components reveal that Tie-integrin recognition is direct, and further demonstrate that the receptor binding domain of the Tie2 ligand (显示 ANGPT2 ELISA试剂盒) Ang-1, but not the receptor binding domain of Ang-2 (显示 ANGPT2 ELISA试剂盒), can independently associate with a5b1 or aVb3. cooperative Tie/integrin interactions selectively stimulate ERK/MAPK (显示 MAPK1 ELISA试剂盒) signaling in the presence of both Ang-1 and fibronectin (显示 FN1 ELISA试剂盒)
Angiopoietin 1 was predominantly present in the maturing glomeruli.
The expression of ANGPT1 has already been studied during metanephric glomerulogenesis, but it remains to be elucidated during the development of the embryonic mesonephros.
Attenuates H2O2-induced stress-activated protein kinase (显示 CDK7 ELISA试剂盒) (SEK)1 (显示 MAP2K4 ELISA试剂盒)/JNK (显示 MAPK8 ELISA试剂盒) phosphorylation through the PI 3 (显示 PI3 ELISA试剂盒)-kinase/Akt (显示 AKT1 ELISA试剂盒) pathway and inhibits the apoptosis of vascular endothelial cells induced by oxidative stress.
Estrogen-dependent control of Ang-1 expression plays an important role in stabilizing meningeal microvessel and maintaining healthy microvascular networks.
Angiopoietin-1 receptor Tie2 (显示 TEK ELISA试剂盒) distinguishes multipotent differentiation capability in bovine coccygeal nucleus pulposus cells.
inhibition of NO production by Ang-1, via phosphorylation of eNOS (显示 NOS3 ELISA试剂盒) on Thr (显示 TRH ELISA试剂盒)(497) by PKC zeta (显示 PRKCZ ELISA试剂盒), is responsible, at least in part, for inhibition of VEGF (显示 VEGFA ELISA试剂盒)-stimulated endothelial permeability by Ang-1.
Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
, angiopoietin 1