Cystatin B (Stefin B) (CSTB) ELISA试剂盒产品概述

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Cystatin B (Stefin B) ELISA试剂盒 (CSTB)
在www.antibodies-online.cn可供28 Cystatin B (Stefin B) (CSTB) ELISA试剂盒的16不同的供货商。 再加上,我们可以发Cystatin B (Stefin B) 抗体 (232)Cystatin B (Stefin B) 蛋白 (32)和数多这个蛋白质的别的产品。 总共310 Cystatin B (Stefin B)产品已列进来了。
别名:
AA960480, ARABIDOPSIS THALIANA PHYTOCYSTATIN 6, ATCYS6, ATCYSB, CPI1, CST6, CSTB, Cyb, cystatin B, Epm1, EPM1A, LOC100008600, LOC100136235, MGC189005, PME, STFB, ULD

引用最多的Cystatin B (Stefin B) ELISA试剂盒

  1. Human CSTB ELISA Kit for Sandwich ELISA - ABIN572364 : Cantres-Rosario, Plaud-Valentín, Gerena, Skolasky, Wojna, Meléndez: Cathepsin B and cystatin B in HIV-seropositive women are associated with infection and HIV-1-associated neurocognitive disorders. in AIDS 2013 (PubMed)
    Show all 6 references for 572364

适于 Cystatin B (Stefin B) 相互作用对的更多 ELISA 试剂盒

Arabidopsis thaliana Cystatin B (Stefin B) (CSTB) interaction partners

  1. The interaction between AtCYSb and AtCaN2 AtCYSb regulates nucleic acid degradation in cells

  2. Data suggests that AtCYS6 expression is enhanced by the germination inhibitory phytohormone ABA and that it participates in the control of germination rate and seedling growth by inhibiting the activity of stored cysteine proteinases. [AtCYS6]

Mouse (Murine) Cystatin B (Stefin B) (CSTB) interaction partners

  1. The data of this study show that CXCL13 (显示 CXCL13 ELISA试剂盒) expression is a hallmark of microglial activation in Cstb (-/-) mice and that the brain inflammation is linked to peripheral inflammatory changes, which might contribute to the disease pathology of progressive myoclonus epilepsy..

  2. CSTB has a role in chemotaxis, antigen-presentation, and in immune- and defense response-associated processes by altering JAK (显示 JAK3 ELISA试剂盒)-STAT (显示 STAT1 ELISA试剂盒) pathway signaling

  3. Deletion of the encoding Cstb gene in Npc1-deficient mice resulted in striking deleterious effects, particularly within the cerebellum where diffuse loss of Purkinje cells was observed in young mice. This may be a consequence of damage to lysosomal membranes by reactive oxygen species (ROS), leading to the leakage of lysosomal contents that culminates in apoptosis.

  4. Results suggest a role for CSTB in regulating microglial activation: data link CSTB deficiency to early activation and altered functional properties of microglia, imply presence of both enhanced and suppressed immune response-related microglial functions

  5. the LPS-induced sepsis in StB KO mice is dependent on caspase-11 and mitochondrial reactive oxygen species but is not associated with the lysosomal destabilization and increased cathepsin activity in the cytosol

  6. These results indicate an in vivo role for Stfb in protecting cancer cells by promoting their resistance to oxidative stress and to apoptosis induced through the lysosomal pathway.

  7. Sefin B influences the expression of anti-inflammatory IL-10 (显示 IL10 ELISA试剂盒) in response to TLR4 (显示 TLR4 ELISA试剂盒) agonists.

  8. An increase in Cstb does not induce any spontaneous epileptic activity.

  9. Pathologic events in the CSTB-deficient brain highlight the potential role of glial activation at the initial stages of progressive myoclonic epilepsy type 1.

  10. this study suggesting that the Cstb-Prmt2 (显示 PRMT2 ELISA试剂盒) region is not playing a major role in locomotor and cognitive deficits found in mice model of Down syndrome.

Human Cystatin B (Stefin B) (CSTB) interaction partners

  1. Homozygous for a c.218dupT (p.His75Serfs*2) mutation in exon 3 of CSTB causes neurodegeneration, progressive cerebral volume loss and diffuse hypomyelination.

  2. CSTB downregulation may promote the development of gastric cancer.

  3. It was shown that decreased expression of cystatin B enhances cathepsin activity in Niemann-Pick C cerebellar degeneration patient fibroblasts.

  4. High expression of stefin B may be an important factor contributing to the development and metastasis of Hepatocellular Carcinoma.

  5. CSTB null mutation associated with microcephaly, early developmental delay, and severe dyskinesia.

  6. Data shows that CYTB (显示 MT-CYB ELISA试剂盒) and ANXA4 (显示 ANXA4 ELISA试剂盒) overexpression may be involved in carcinogenesis and histopathological differentiation of ovarian clear cell carcinoma and suggest they may serve as a potential diagnostic biomarkers.

  7. A role for disease-causing mutations in cystatin B gene in patients with juvenile myoclonic epilepsy was not supported.

  8. Even though the majority of EPM1 patients have a uniform genetic mutation, the actual size of the longer CSTB expansion mutation allele is likely to have a modulating effect on the age at disease onset, myoclonus severity, and cortical neurophysiology.

  9. The study shows detection of stefin B dimers in HEK293 cells and the importance of their residual activity.

  10. glutamate (显示 GRIN1 ELISA试剂盒) dehydrogenase is a euchromatin-associated enzyme, and its H3 clipping activity is regulated by chromatin structure, histone modifications and an in vivo inhibitor.

Cystatin B (Stefin B) (CSTB) 抗原简介

Antigen Summary

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1).

Alternative names and synonyms associated with Cystatin B (Stefin B) (CSTB)

  • cystatin B (stefin B) (CSTB) Elisa Kit
  • cystatin B (stefin B) (cstb) Elisa Kit
  • zgc:56530 (zgc:56530) Elisa Kit
  • cysteine proteinase inhibitor 6 (CYSB) Elisa Kit
  • cystatin B (LOC100008600) Elisa Kit
  • cystatin B (LOC100136235) Elisa Kit
  • cystatin B (Cstb) Elisa Kit
  • cystatin B (stefin B) (Cstb) Elisa Kit
  • AA960480 Elisa Kit
  • ARABIDOPSIS THALIANA PHYTOCYSTATIN 6 Elisa Kit
  • ATCYS6 Elisa Kit
  • ATCYSB Elisa Kit
  • CPI1 Elisa Kit
  • CST6 Elisa Kit
  • CSTB Elisa Kit
  • Cyb Elisa Kit
  • cystatin B Elisa Kit
  • Epm1 Elisa Kit
  • EPM1A Elisa Kit
  • LOC100008600 Elisa Kit
  • LOC100136235 Elisa Kit
  • MGC189005 Elisa Kit
  • PME Elisa Kit
  • STFB Elisa Kit
  • ULD Elisa Kit

Protein level used designations for CSTB

cystatin B (stefin B) , cystatin-B , stefin B , cystatin B , Leukocyte cysteine proteinase inhibitor 1 , stefin-B , CPI-B , liver thiol proteinase inhibitor , cystatin beta , cystatin-beta , cystatin B protein , stefin C , stefin-C

GENE ID SPECIES
100433135 Pongo abelii
418267 Gallus gallus
713504 Macaca mulatta
770618 Gallus gallus
100127781 Xenopus (Silurana) tropicalis
100170534 Xenopus (Silurana) tropicalis
792225 Danio rerio
820428 Arabidopsis thaliana
100008600 Oryctolagus cuniculus
100136235 Oncorhynchus mykiss
13014 Mus musculus
1476 Homo sapiens
25308 Rattus norvegicus
100038020 Sus scrofa
514170 Bos taurus
478424 Canis lupus familiaris
101123265 Ovis aries
512805 Bos taurus
100980572 Pan paniscus
458593 Pan troglodytes
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