anti-GTPase, IMAP Family Member 5 (GIMAP5) 抗体产品概述

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anti-GTPase, IMAP Family Member 5 抗体 (GIMAP5)
在www.antibodies-online.cn可供49 GTPase, IMAP Family Member 5 (GIMAP5) 抗体的12不同的供货商。 再加上,我们可以发GTPase, IMAP Family Member 5 蛋白 (9)和数多这个蛋白质的别的产品。 总共67 GTPase, IMAP Family Member 5产品已列进来了。
别名:
D630024P16, E230026N22Rik, GIMAP5, HIMAP3, IAN-5, IAN4, Ian4l1, Ian5, IMAP3, IROD

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  1. Horse (Equine) Polyclonal GIMAP5 Primary Antibody for WB - ABIN2782965 : Shin, Janer, McNeney, Blay, Deutsch, Sanjeevi, Kockum, Lernmark, Graham, Arnqvist, Björck, Eriksson, Nyström, Ohlson, Scherstén, Ostman, Aili, Bååth, Carlsson, Edenwall, Forsander, Granström, Gustavsson, Hanås, Hellenberg, Hellgren, Holmberg, Hörnell, Iva: IA-2 autoantibodies in incident type I diabetes patients are associated with a polyadenylation signal polymorphism in GIMAP5. in Genes and immunity 2007 (PubMed)

更多抗GTPase, IMAP Family Member 5的相互作用对抗体

Human GTPase, IMAP Family Member 5 (GIMAP5) interaction partners

  1. These data,demonstrating the downregulation of the mRNA and protein expression levels of GIMAP5 and GIMAP6 (显示 GIMAP6 抗体) in the tumor tissues and blood of patients with HCC (显示 FAM126A 抗体), suggested the involvement of GIMAP5 and GIMAP6 (显示 GIMAP6 抗体) in the pathogenesis of HCC (显示 FAM126A 抗体), and indicate their possible use as diagnostic markers for HCC (显示 FAM126A 抗体).

  2. gimap5 has a role in maintaining peripheral tolerance and T cell homeostasis in the gut (显示 GUSB 抗体) [review]

  3. Data indicate that overexpression of GTPase (显示 RACGAP1 抗体) of the immune-associated nucleotide (显示 GIMAP8 抗体)-binding protein (显示 COASY 抗体) 5 (显示 CAPS 抗体) (GIMAP5) in HEK (显示 EPHA3 抗体) (human embryonic kidney)-293 cells resulted in increased Ca2 (显示 CA2 抗体)+ accumulation within the mitochondria.

  4. Notch (显示 NOTCH1 抗体) signalling protects T-ALL cells from apoptosis by upregulating the expression of GIMAP5.

  5. These data establish Gimap5 as a key regulator of hematopoietic integrity and lymphocyte homeostasis

  6. A significant increase in systemic lupus erythematosus risk associated with the most common GIMAP5 haplotype was found (odds ratio 1.26, 95% CI 1.02 to 1.54, p = 0.0033).

  7. Resutls show that Gimap5 is located in the endoplasmic reticulum, and the endogenous Gimap5 mRNA is up-regulated in activated T-cells.

  8. These data suggest that the GIMAP5 gene is associated with islet autoimmunity in type I diabetes and add to recent findings implicating the same single nucleotide polymorphism in another autoimmune disease.

  9. Data show that IAN5 polymorphisms are associated with susceptibility to Systemic lupus erythematosus and the development of clinical disease manifestations in a strictly Korean population.

Mouse (Murine) GTPase, IMAP Family Member 5 (GIMAP5) interaction partners

  1. functional Gimap5 is required for optimal signaling through TCR and IL-7R in T cells.

  2. gimap5 (显示 GIMAP3 抗体) has a role in maintaining peripheral tolerance and T cell homeostasis in the gut (显示 GUSB 抗体) [review]

  3. The defects in T-cell cellularity were more severe in mice lacking both Gimap3 (显示 GIMAP3 抗体) and Gimap5 (显示 GIMAP3 抗体).

  4. a novel link between Gimap5 (显示 GIMAP3 抗体) and Foxo (显示 FOXO3 抗体) expression and provide evidence for a regulatory mechanism that controls Foxo (显示 FOXO3 抗体) protein expression and may help to maintain immunological tolerance.

  5. Gimap5 (显示 GIMAP3 抗体) is an important stabilizer of mouse hematopoietic progenitor cell survival.

  6. mouse gimap5 (显示 GIMAP3 抗体) is necessary for the survival of peripheral T cells, NK/NKT (显示 CTSL1 抗体)-cell development, and the maintenance of normal liver function

GTPase, IMAP Family Member 5 (GIMAP5) 抗原简介

Antigen Summary

This gene encodes a protein belonging to the GTP-binding superfamily and to the immuno-associated nucleotide (IAN) subfamily of nucleotide-binding proteins. In humans, the IAN subfamily genes are located in a cluster at 7q36.1. This gene encodes an antiapoptotic protein that functions in T-cell survival. Polymorphisms in this gene are associated with systemic lupus erythematosus. Read-through transcription exists between this gene and the neighboring upstream GIMAP1 (GTPase, IMAP family member 1) gene.

Alternative names and synonyms associated with GTPase, IMAP Family Member 5 (GIMAP5)

  • GTPase, IMAP family member 5 (GIMAP5) 抗体
  • GTPase, IMAP family member 2 (GIMAP2) 抗体
  • GTPase, IMAP family member 5 (Gimap5) 抗体
  • D630024P16 抗体
  • E230026N22Rik 抗体
  • GIMAP5 抗体
  • HIMAP3 抗体
  • IAN-5 抗体
  • IAN4 抗体
  • Ian4l1 抗体
  • Ian5 抗体
  • IMAP3 抗体
  • IROD 抗体

Protein level used designations for GIMAP5

GTPase, IMAP family member 5 , GTPase IMAP family member 5 , immune associated nucleotide 4 like 1 , immunity associated protein 3 , immunity-associated nucleotide 5 protein , inhibitor of radiation- and OA-induced apoptosis, Irod/Ian5 , immunity-associated nucleotide 4-like 1 protein , immunity-associated protein 3 , IAN-4 , immunity-associated nucleotide 4 protein

GENE ID SPECIES
420413 Gallus gallus
463896 Pan troglodytes
482797 Canis lupus familiaris
505013 Bos taurus
55340 Homo sapiens
317757 Mus musculus
246774 Rattus norvegicus
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