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anti-CD226 (CD226) 抗体产品概述

Full name:
anti-CD226 Molecule 抗体 (CD226)
在www.antibodies-online.cn可供193 CD226 Molecule (CD226) 抗体的21不同的供货商。 再加上,我们可以发CD226 蛋白 (21)CD226 试剂盒 (12)和数多这个蛋白质的别的产品。 总共238 CD226产品已列进来了。
别名:
BC051526, cd226, DNAM-1, DNAM1, PTA1, TLiSA1, zgc:158817

最受欢迎的抗anti-CD226 (CD226) 抗体

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抗Mouse (Murine) CD226 抗体:

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引用最多的anti-CD226 抗体

  1. Human Monoclonal CD226 Primary Antibody for Func, FACS - ABIN119797 : Kojima, Kanada, Shimizu, Kasama, Shibuya, Nakauchi, Nagasawa, Shibuya: CD226 mediates platelet and megakaryocytic cell adhesion to vascular endothelial cells. in The Journal of biological chemistry 2003 (PubMed)
    Show all 3 references for ABIN119797

  2. Human Monoclonal CD226 Primary Antibody for FACS - ABIN119800 : Shibuya, Campbell, Hannum, Yssel, Franz-Bacon, McClanahan, Kitamura, Nicholl, Sutherland, Lanier, Phillips: DNAM-1, a novel adhesion molecule involved in the cytolytic function of T lymphocytes. in Immunity 1996 (PubMed)
    Show all 3 references for ABIN119800

  3. Human Monoclonal CD226 Primary Antibody for FACS - ABIN119796 : Shibuya, Lanier, Phillips: Protein kinase C is involved in the regulation of both signaling and adhesion mediated by DNAX accessory molecule-1 receptor. in Journal of immunology (Baltimore, Md. : 1950) 1998 (PubMed)
    Show all 3 references for ABIN119796

  4. Human Monoclonal CD226 Primary Antibody for FACS, Neut - ABIN4899392 : Magnani, Alberigo, Bacchetta, Serafini, Andreani, Roncarolo, Gregori: Killing of myeloid APCs via HLA class I, CD2 and CD226 defines a novel mechanism of suppression by human Tr1 cells. in European journal of immunology 2011 (PubMed)

  5. Human Monoclonal CD226 Primary Antibody for FACS - ABIN4896039 : Liu, Qian, Chen, Xu, Gao, Zhang, Zhang, Qi, Gao, Yan: Crystal structure of cell adhesion molecule nectin-2/CD112 and its binding to immune receptor DNAM-1/CD226. in Journal of immunology (Baltimore, Md. : 1950) 2012 (PubMed)

  6. Human Monoclonal CD226 Primary Antibody for FACS - ABIN1449203 : Shibuya, Shirakawa, Kameyama, Honda, Tahara-Hanaoka, Miyamoto, Onodera, Sumida, Nakauchi, Miyoshi, Shibuya: CD226 (DNAM-1) is involved in lymphocyte function-associated antigen 1 costimulatory signal for naive T cell differentiation and proliferation. in The Journal of experimental medicine 2003 (PubMed)

更多抗CD226的相互作用对抗体

Mouse (Murine) CD226 Molecule (CD226) interaction partners

  1. Data show that CD155 (显示 PVR 抗体) protein/CD226 antigen mainly mediates the interaction between NK cells and leukemic cells in acute myeloid leukemia (显示 BCL11A 抗体). To investigate the interaction between leukemic cells

  2. absence of either CD155 (显示 PVR 抗体) or CD226 in BALB/c mice causes a profound shift in the Natural Killer T-Cells subtype composition in thymus, expanding the frequency and numbers of iNKT1 cells at the expense of iNKT2 cells, as well as iNKT17 cells.

  3. our results suggest a limited role for DNAM-1 in solid allograft rejection. Blocking DNAM-1 is not sufficient to prevent allograft rejection and might be relevant only in combination with additional inhibitors of costimulation.

  4. we propose that expression of DNAM-1 on inflammatory monocytes are evolutionally conserved and act as an adhesion molecule (显示 NCAM1 抗体) on blood inflammatory monocytes.

  5. Data indicate that DNAM-1 (CD226) signaling was required to enhance cytotoxicity.

  6. Regulatory T cells derived (显示 CD4 抗体)from Cd226-deficient mice showed similarly reduced inhibitory activity, eventually resulting in an exacerbated disease course of experimental autoimmune encephalomyelitis.

  7. CD226 limits spontaneous multiple myeloma development in Vk*MYC (显示 MYC 抗体) transgenic mice. This is mediated both by NK and CD8 (显示 CD8A 抗体)+ T cells through perforin (显示 PRF1 抗体) and IFN-gamma (显示 IFNG 抗体) pathways. It also is needed for cyclophosphamide and bortezomib treatment effectiveness.

  8. Findings suggest that TIGIT (显示 TIGIT 抗体) is a key checkpoint inhibitor of chronic antiviral and antitumor responses through impairing CD226 function when disrupting its homodimerization.

  9. This synapse defect may explain why DNAM-1-deficient mice cannot clear tumors in vivo.

  10. cooperative signaling through DNAM-1 and Ly49H (显示 KLRA8 抗体) are required for NK cell-mediated host defense against MCMV infection

Human CD226 Molecule (CD226) interaction partners

  1. our results support and explain the mechanism behind the recently reported finding that in EOC, NK-cell recognition and killing of tumor cells was mainly dependent on DNAM-1 signaling while the contribution of the NKG2D (显示 KLRK1 抗体) receptor-ligand pathway was complementary and uncertain.

  2. CD226 rs763361 polymorphism was significantly associated with susceptibility to T1D.

  3. Age and CMV serostatus influence the expression of NKp30 (显示 NCR3 抗体), NKp46 (显示 NCR1 抗体) and DNAM-1 activating receptors on resting and IL-2 (显示 IL2 抗体) activated natural killer cells.

  4. we propose that expression of DNAM-1 on inflammatory monocytes are evolutionally conserved and act as an adhesion molecule (显示 NCAM1 抗体) on blood inflammatory monocytes.

  5. DNAM-1 ligands CD112 (显示 PVRL2 抗体) and CD155 (显示 PVR 抗体) as well as the NKG2D (显示 KLRK1 抗体) ligands MICA (显示 MICA 抗体) and MICB (显示 MICB 抗体) were expressed on the hiPSC lines

  6. The CD226 gene has been identified as novel association with JIA, and a SNP near CD28 (显示 CD28 抗体) as a suggestive association.

  7. Effector and regulatory CD4 (显示 CD4 抗体)+ memory T cells of healthy individuals carrying the predisposing CD226 variant showed, in comparison to carriers of the protective variant, reduced surface expression of CD226 and impaired induction of CD226 after stimulation.

  8. The present study provides evidence that regulation of the PVR/CD155 (显示 PVR 抗体) DNAM-1 ligand expression by nitric oxide may represent an additional immune-mediated mechanism and supports the anti-myeloma activity of nitric oxide donors.

  9. our data reveal the existence of a functional program of NK cell maturation marked by DNAM-1 expression.

  10. upregulated CD226 expression on CD8 (显示 CD8A 抗体)(+) T cells reflects disease severity and is involved in Systemic sclerosis pathogenesis via the production of various cytokines, including profibrotic IL-13 (显示 IL13 抗体) and endothelial cell injury

CD226 抗原简介

Antigen Summary

This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation.

Alternative names and synonyms associated with CD226

  • CD226 molecule (CD226) 抗体
  • CD226 antigen (cd226) 抗体
  • CD226 molecule (cd226) 抗体
  • CD226 antigen (Cd226) 抗体
  • CD226 molecule (Cd226) 抗体
  • BC051526 抗体
  • cd226 抗体
  • DNAM-1 抗体
  • DNAM1 抗体
  • PTA1 抗体
  • TLiSA1 抗体
  • zgc:158817 抗体

Protein level used designations for anti-CD226 Molecule (CD226) 抗体

CD226 antigen , CD226 molecule , platelet and T cell activation antigen 1 , platelet and T-cell activation antigen 1 , DNAX accessory molecule 1 , DNAX accessory molecule-1 , T lineage-specific activation antigen 1 antigen , adhesion glycoprotein

GENE ID SPECIES
468577 Pan troglodytes
609196 Canis lupus familiaris
100194885 Salmo salar
791164 Danio rerio
772097 Gallus gallus
100579250 Nomascus leucogenys
225825 Mus musculus
10666 Homo sapiens
615496 Bos taurus
307199 Rattus norvegicus
703878 Macaca mulatta
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