G Protein-Coupled Receptor Kinase 1 (GRK1) ELISA试剂盒产品概述

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G Protein-Coupled Receptor Kinase 1 ELISA试剂盒 (GRK1)
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CG40129, CT4320, Dmel\\CG40129, Gprk-1, Gprk1, grk1, Rhok, Rk, Rok

G Protein-Coupled Receptor Kinase 1 (GRK1) ELISA试剂盒 by Reactivity

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适于 G Protein-Coupled Receptor Kinase 1 相互作用对的更多 ELISA 试剂盒

Human G Protein-Coupled Receptor Kinase 1 (GRK1) interaction partners

  1. Gene analysis determined a novel GRK1 mutation c.923T>C, which caused Oguchi disease in all siblings. This mutation, was demonstrated by amino acid alignment analysis to be in a phylogenetically conserved region and resulted in an amino acid change from leucine to proline at position 308. Thus, the present study reports a novel missense mutation of GRK1 in the affected members of a consanguineous Turkish family.

  2. AAMP (显示 AAMP ELISA试剂盒) Regulates Endothelial Cell Migration and Angiogenesis Through RhoA (显示 RHOA ELISA试剂盒)/Rho Kinase (显示 ROCK1 ELISA试剂盒) Signaling.

  3. In the Ca(2 (显示 CA2 ELISA试剂盒)+)/NCS-1 (显示 NCS1 ELISA试剂盒).D2R (显示 DRD2 ELISA试剂盒) peptide complex, the C-terminal region adopts a 310 helix-turn-310 helix, whereas in the GRK1 peptide complex it forms an a-helix

  4. Rho-kinase (显示 ROCK1 ELISA试剂盒) activity exhibits distinct circadian variation associated with alterations in coronary vasomotor responses and autonomic activity in VSA patients.

  5. The selective thinning of the inner retinal layers in patients with GRM6 (显示 GRM6 ELISA试剂盒) mutations suggests either reduced bipolar or ganglion cell numbers or altered synaptic structure in the inner retina.

  6. Defects in GRK1 or GRK7 (显示 GRK7 ELISA试剂盒) cause patients to suffer from an inability to properly deactivate rhodopsin (显示 RHO ELISA试剂盒) leading to problems with recovery and dark adaptation.

  7. There are two genes that cause Oguchi disease: the G protein-coupled receptor kinase 1 gene and the S antigen (显示 SAG ELISA试剂盒) gene. There is evidence that Oguchi disease and retinitis pigmentosa (RP) can coexist in the same family or even in the same individual

  8. Phosphorylation of GRK1 and GRK7 by PKA occurs in the dark, when cAMP levels in photoreceptor cells are elevated.

  9. The disease in the Pakistani family localizes to 13q34 and is caused by a novel deletion including Exon 3 of the GRK1 gene.

  10. G protein-coupled receptor kinase site serine cluster has a role in beta2-adrenergic receptor internalization, desensitization, and beta-arrestin translocation

Cow (Bovine) G Protein-Coupled Receptor Kinase 1 (GRK1) interaction partners

  1. The C-terminal segment in GCAP2 (显示 GUCA1B ELISA试剂盒) confers target selectivity, facilitates membrane binding and provides sensitivity of the membrane localization of the protein to phosphorylation by rhodopsin kinase.

  2. The methylation status of GRK1 is affected by nucleotide binding and by the levels of free Ca2 (显示 CA2 ELISA试剂盒) + via recoverin (显示 RCVRN ELISA试剂盒).

  3. crystalline dimer interface was disrupted with a L166K mutation and the structure of GRK1-L166K was determined in complex with Mg(2 (显示 MCOLN1 ELISA试剂盒)+) . ATP to 2.5 A resolution

  4. A novel rhodopsin-kinase-binding site within the C-terminal region of recoverin (显示 RCVRN ELISA试剂盒).

  5. similar to transducin (显示 GNAT1 ELISA试剂盒) activation, rhodopsin (显示 RHO ELISA试剂盒) phosphorylation by GRK1 and high affinity arrestin-1 (显示 SAG ELISA试剂盒) binding only requires a rhodopsin (显示 RHO ELISA试剂盒) monomer

  6. Recoverin (显示 RCVRN ELISA试剂盒) and rhodopsin kinase have roles in a Ca2 (显示 CA2 ELISA试剂盒)+-dependent feedback loop in membrane rafts from rod outer segments

  7. an interaction surface for the recoverin (显示 RCVRN ELISA试剂盒) target rhodopsin kinase is constituted upon Ca2 (显示 CA2 ELISA试剂盒)+ binding to the non-acylated mutant

  8. Recoverin (显示 RCVRN ELISA试剂盒) binds exclusively to an amphipathic peptide at the N terminus of rhodopsin kinase

  9. Ca(2 (显示 CA2 ELISA试剂盒)+)-bound recoverin (显示 RCVRN ELISA试剂盒) is bound between rhodopsin (显示 RHO ELISA试剂盒) and RK in a ternary complex on rod outer segment disk membranes, thereby blocking RK interaction with rhodopsin (显示 RHO ELISA试剂盒) at high Ca(2 (显示 CA2 ELISA试剂盒)+)

  10. key elements of rhodopsin kinase in different ligand states are involved in G protein-coupled receptor (显示 GPBAR1 ELISA试剂盒) kinase activation

Mouse (Murine) G Protein-Coupled Receptor Kinase 1 (GRK1) interaction partners

  1. The retinal phenotype of Grk1-/- mice is compromised by a Crb1 (显示 CRB1 ELISA试剂盒) rd8 mutation.

  2. Rods and cones share the same isoforms of recoverin (显示 RCVRN ELISA试剂盒) and GRK1, and photoactivation also triggers a calcium decline in cones

  3. Knockout of Unc119 (显示 UNC119 ELISA试剂盒) partially reversed the transport defect of GRK1 in cone photoreceptors caused by deletion of Pde6d (显示 PDE6D ELISA试剂盒).

  4. rhodopsin kinase may modulate the decay of light-activated PDE (显示 TWIST1 ELISA试剂盒)*, which may be responsible for the quickening of response recovery in background light.

  5. Altering the expression of GRK1 from 0.3- to 3-fold that in wild-type rods had little effect on the single photon response amplitude.

  6. phototransduction does not play a direct role in the light-dependent dephosphorylation of GRK1.

  7. PLCdelta3 negatively regulates RhoA (显示 RHOA ELISA试剂盒) expression, inhibits RhoA (显示 RHOA ELISA试剂盒)/Rho kinase (显示 ROCK2 ELISA试剂盒) signaling, and thereby promotes neurite extension.

  8. The results of this study demonstrated a light-independent mechanism for retinal degeneration in the absence of GRK1, suggesting a second, not previously recognized role for that kinase.

  9. Nrl (显示 NRL ELISA试剂盒) and Grk1 have roles in photoresponse recovery and age-related degeneration

  10. transport of prenylated proteins, particularly GRK1 and cone phosphodiesterase, to rod and cone outer segments

G Protein-Coupled Receptor Kinase 1 (GRK1) 抗原简介

Antigen Summary

Specifically phosphorylates the activated forms of G protein-coupled receptors (By similarity).

Alternative names and synonyms associated with G Protein-Coupled Receptor Kinase 1 (GRK1)

  • G protein-coupled receptor kinase 1 (Gprk1) Elisa Kit
  • G protein-coupled receptor kinase 1 a (grk1a) Elisa Kit
  • G protein-coupled receptor kinase 1 (GRK1) Elisa Kit
  • G protein-coupled receptor kinase 1 (Grk1) Elisa Kit
  • CG40129 Elisa Kit
  • CT4320 Elisa Kit
  • Dmel\\CG40129 Elisa Kit
  • Gprk-1 Elisa Kit
  • Gprk1 Elisa Kit
  • grk1 Elisa Kit
  • Rhok Elisa Kit
  • Rk Elisa Kit
  • Rok Elisa Kit

Protein level used designations for GRK1

CG40129-PA , CG40129-PB , Gprk1-PA , Gprk1-PB , rhodopsin kinase , G-protein-coupled receptor kinase 1a , G-protein coupled receptor kinase 1 , RK , G-protein receptor kinase 1 , G protein-coupled receptpr kinase 1

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564152 Danio rerio
395431 Gallus gallus
6011 Homo sapiens
281457 Bos taurus
24013 Mus musculus
81760 Rattus norvegicus
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