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anti-Dihydropyrimidinase-Like 2 (DPYSL2) 抗体产品概述

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anti-Dihydropyrimidinase-Like 2 抗体 (DPYSL2)
在www.antibodies-online.cn可供131 Dihydropyrimidinase-Like 2 (DPYSL2) 抗体的18不同的供货商。 再加上,我们可以发Dihydropyrimidinase-Like 2 试剂盒 (16)Dihydropyrimidinase-Like 2 蛋白 (8)和数多这个蛋白质的别的产品。 总共161 Dihydropyrimidinase-Like 2产品已列进来了。
别名:
AI851130, CRMP-2, Crmp2, CRMP 2, CRMP2A, DHPRP2, dpysl2, DRP-2, DRP2, Musunc33, N2A3, PCRMP-2, PCRMP 2, PCRMP2, PfCRMP-2, PfCRMP 2, TOAD-64, ULIP-2, ULIP2, unc-33, unc33

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引用最多的anti-Dihydropyrimidinase-Like 2 抗体

  1. Human Polyclonal DPYSL2 Primary Antibody for IHC, ELISA - ABIN1533164 : Goshima, Nakamura, Strittmatter, Strittmatter: Collapsin-induced growth cone collapse mediated by an intracellular protein related to UNC-33. in Nature 1995 (PubMed)
    Show all 2 references for ABIN1533164

  2. Human Polyclonal DPYSL2 Primary Antibody for IHC, ELISA - ABIN1532136 : Miki, Swensen, Shattuck-Eidens, Futreal, Harshman, Tavtigian, Liu, Cochran, Bennett, Ding: A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. in Science (New York, N.Y.) 1994 (PubMed)
    Show all 2 references for ABIN1532136

  3. Cow (Bovine) Polyclonal DPYSL2 Primary Antibody for IP, WB - ABIN2784711 : Patrakitkomjorn, Kobayashi, Morikawa, Wilson, Tsubota, Irie, Ozawa, Aoki, Arimura, Kaibuchi, Saya, Araki: Neurofibromatosis type 1 (NF1) tumor suppressor, neurofibromin, regulates the neuronal differentiation of PC12 cells via its associating protein, CRMP-2. in The Journal of biological chemistry 2008 (PubMed)

  4. Human Monoclonal DPYSL2 Primary Antibody for IF, ELISA - ABIN515065 : OBrien, Shen, Tachikawa, Lee, Briggs: Quantitative proteome analysis of pluripotent cells by iTRAQ mass tagging reveals post-transcriptional regulation of proteins required for ES cell self-renewal. in Molecular & cellular proteomics : MCP 2010 (PubMed)

更多抗Dihydropyrimidinase-Like 2的相互作用对抗体

Mouse (Murine) Dihydropyrimidinase-Like 2 (DPYSL2) interaction partners

  1. Results suggested that crmp2 is a target of miR (显示 MLXIP 抗体)-181c and that the abnormally low expression of miR (显示 MLXIP 抗体)-181c in the hippocampus of SAMP8 mice could lead to an increase of the crmp2 protein level in Alzheimer's disease mice, which might potentially play a role in the pathogenesis of Alzheimer's disease

  2. These results suggest a correlation between CRMP2 phosphorylation and AD pathophysiology, and indicate the effectiveness of pioglitazone treatment at the pre-Abeta (显示 APP 抗体) accumulation stage in AD model mice.

  3. We generated CRMP2 gene-deficient (crmp2(-/-) ) mice. The crmp2(-/-) mice showed irregular development of dendritic spines in cortical neurons. The level of CRMP1 (显示 CRMP1 抗体) was increased in crmp2(-/-) , but the level of CRMP2 was not altered in crmp1 (显示 CRMP1 抗体)(-/-).The phenotypic defects had no genetic interaction between crmp1 (显示 CRMP1 抗体) and crmp2.

  4. study implies that dysregulation of CRMP2 may be involved in pathophysiology of neuropsychiatric disorders

  5. we demonstrate that Cdk5 (显示 CDK5 抗体) phosphorylates collapsin response mediator protein 2 (CRMP2) in the dendritic spines of cultured hippocampal neurons and in vivo in the mouse brain. When we eliminated CRMP2 phosphorylation in CRMP2(KI/KI (显示 AXIN1 抗体)) mice, the densities of dendritic spines significantly decreased in hippocampal CA1 (显示 CA1 抗体) pyramidal neurons in the mouse brain.

  6. We propose that CRMP2 could contribute to long-lasting synaptic plasticity.

  7. This study shows that in young adult mice, motor and sensory functions lost by SCI can be recovered with a single genetic mutation to inhibit CRMP2 phosphorylation

  8. Study showed that axon degeneration is an early and dominant feature in dopaminergic neurons treated with 1-methyl-4-phenylpyridiniumion (MPP+), and that the Akt/GSK-3beta/CRMP-2 pathway is involved in axon degeneration induced by MPP+

  9. Clear differences in CRMP2 protein abundance and degradation product/short isoform were observed between ischemic core and penumbra (显示 TSPAN33 抗体) and also compared to the contralateral healthy tissues after PACAP38 (显示 ADCYAP1 抗体) or saline treatment.

  10. Glycogen synthase kinase 3beta has a role in microtubule remodeling in compensatory glomerular adaptation to podocyte depletion through Tau and CRMP2

Human Dihydropyrimidinase-Like 2 (DPYSL2) interaction partners

  1. These data identify a novel oncogenic mechanism where CDK5 (显示 CDK5 抗体) activation induces CRMP2A phosphorylation in the nuclei of tumour cells

  2. polymorphisms of the DPYSL2 gene in humans may be associated with the development of schizophrenia.

  3. Functional variants in DPYSL2 sequence increase risk of schizophrenia and suggest a link to mTOR (显示 FRAP1 抗体) signaling

  4. Changes for CRMP2, TCP1epsilon, TPM2 (显示 TPM2 抗体) and 14-3-3gamma (显示 YWHAG 抗体) were confirmed in experimental tumors and in a series of 28 human SI-NETs.

  5. Reduced CRMP2 expression and elevated expression of nuclear phosphorylated CRMP2 may be associated with breast cancer progression.

  6. Levels of total GSK3 (显示 GSK3b 抗体) were decreased in the Huntington disease (显示 HTT 抗体)-affected frontal cortex and this correlated with decreased phosphorylated CRMP2.

  7. High dihydropyrimidinase-related protein 2 expression is associated with lung cancer.

  8. genetic variants in DPYSL2 may play a role in susceptibility to alcohol dependence.

  9. A specific and reversible intermolecular Cys (显示 DNAJC5 抗体)-504-Cys (显示 DNAJC5 抗体)-504 dithiol-disulfide switch in homotetrameric CRMP2 determines two conformations of the quaternary CRMP2 complex that controls axonal outgrowth and thus neuronal development.

  10. CRMP-2-dependent regulation of ROCK II (显示 ROCK2 抗体) activity is mediated through interaction of the CRMP-2L N terminus with the ROCK II (显示 ROCK2 抗体) catalytic domain as well as by GSK3 (显示 GSK3b 抗体)-dependent phosphorylation of CRMP-2.

Zebrafish Dihydropyrimidinase-Like 2 (DPYSL2) interaction partners

  1. phosphorylation of Dpysl2 and Dpysl3 (显示 DPYSL3 抗体) by Cyclin-dependent kinase 5 (显示 CDK5 抗体) and dual-specificity tyrosine-phosphorylated and regulated kinase 2 is required for correct positioning of CaP motor neurons in the zebrafish spinal cord

  2. These results suggest that the phosphorylation of Dpysl2 and Dpysl3 (显示 DPYSL3 抗体) by Cdk5 (显示 CDK5 抗体) and DYRK2 (显示 DYRK2 抗体) is required for the proper positioning of Rohon-Beard neurons and neural crest cells during neurulation in zebrafish embryos.

  3. From 20 somites through 30 hpf CRMP2 is expressed in the dorsal rostral cluster of the telencephalon, the ventral rostral cluster of the diencephalon, the ventral caudal (显示 CAD 抗体) cluster of the mesencephalon, and the hindbrain clusters.

Dihydropyrimidinase-Like 2 (DPYSL2) 抗原简介

Antigen Summary

This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Alternative names and synonyms associated with Dihydropyrimidinase-Like 2 (DPYSL2)

  • dihydropyrimidinase-like 2 (DPYSL2) 抗体
  • cysteine repeat modular protein 2, putative (PfCRMP2) 抗体
  • dihydropyrimidinase-like 2 (dpysl2) 抗体
  • dihydropyrimidinase-like 2 (Dpysl2) 抗体
  • dihydropyrimidinase-like 2b (dpysl2b) 抗体
  • AI851130 抗体
  • CRMP-2 抗体
  • Crmp2 抗体
  • CRMP 2 抗体
  • CRMP2A 抗体
  • DHPRP2 抗体
  • dpysl2 抗体
  • DRP-2 抗体
  • DRP2 抗体
  • Musunc33 抗体
  • N2A3 抗体
  • PCRMP-2 抗体
  • PCRMP 2 抗体
  • PCRMP2 抗体
  • PfCRMP-2 抗体
  • PfCRMP 2 抗体
  • TOAD-64 抗体
  • ULIP-2 抗体
  • ULIP2 抗体
  • unc-33 抗体
  • unc33 抗体

Protein level used designations for DPYSL2

collapsin response mediator protein 2 , dihydropyrimidinase-like 2 , DRP-2 , dihydropyrimidinase-related protein 2 , dihydropyrimidinase-related protein 2-like , ULIP-2 , unc-33-like phosphoprotein 2 , CRMP-2 , turned on after division 64 kDa protein , turned on after division, 64 kDa protein , collapsin response mediator protein hCRMP-2 , collapsin response mediator protein CRMP-62 , collapsin response mediator protein-2A , neural-specific protein NSP60 , turned on after division 64

GENE ID SPECIES
554340 Felis catus
2655054 Plasmodium falciparum 3D7
100158561 Xenopus (Silurana) tropicalis
100172763 Pongo abelii
464070 Pan troglodytes
712368 Macaca mulatta
100351135 Oryctolagus cuniculus
100391260 Callithrix jacchus
100580649 Nomascus leucogenys
12934 Mus musculus
25416 Rattus norvegicus
1808 Homo sapiens
398815 Xenopus laevis
395155 Gallus gallus
486107 Canis lupus familiaris
533746 Bos taurus
553412 Danio rerio
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