RASA1 (RASA1) ELISA试剂盒产品概述

Full name:
RAS P21 Protein Activator (GTPase Activating Protein) 1 ELISA试剂盒 (RASA1)
在www.antibodies-online.cn可供5 RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) ELISA试剂盒的3不同的供货商。 再加上,我们可以发RASA1 抗体 (107)RASA1 蛋白 (5)和数多这个蛋白质的别的产品。 总共123 RASA1产品已列进来了。
CG9209, CM-AVM, CMAVM, D-RasGAP, Dmel\\CG9209, Gap, GAPX, p120GAP, p120RASGAP, PKWS, RAS-GAP, Rasa, RASGAP
list all ELISA KIts 基因 基因ID UniProt
RASA1 5921 P20936
RASA1 25676 P50904
RASA1 218397  



适于 RASA1 相互作用对的更多 ELISA 试剂盒

Human RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) interaction partners

  1. Low RASA1 expression is associated with Triple-Negative Breast Cancer.

  2. QKI-5 (显示 QKI ELISA试剂盒) stabilized RASA1 mRNA via directly binding to the QKI (显示 QKI ELISA试剂盒) response element region of RASA1, which in turn prevented the activation of the Ras-MAPK (显示 MAPK1 ELISA试剂盒) signaling pathway, suppressed cellular proliferation and induced cell cycle arrest.

  3. Data show that patients with low level of Ras GTPase-activating protein 1 (RASA1) expression correlated with a significantly poorer survival compared to those with high level of RASA1 expression.

  4. Results show that oncogenic KRAS can activate Rho through miR-31-mediated regulation of RASA1 indicating miR-31 acts as a KRAS effector to modulate invasion and migration in pancreatic cancer.

  5. PTP1B (显示 PTPN1 ELISA试剂盒) dephosphorylates PITX1 (显示 PITX1 ELISA试剂盒) to weaken its protein stability and the transcriptional activity for p120RasGAP gene expression

  6. Data suggest that, in response to netrin-1 (显示 NTN1 ELISA试剂盒)/netrin receptor (DCC (显示 DCC ELISA试剂盒)) signaling, p120RasGAP is recruited to growth cones and supports axon outgrowth; p120RasGAP Src (显示 SRC ELISA试剂盒) homology 2 domains exhibit scaffolding properties sufficient to support axon outgrowth.

  7. Maternal and fetal capillary malformation-arteriovenous malformation due to a novel RASA1 mutation presenting with prenatal non-immune hydrops fetalis have been found.

  8. This is the second largest study on isolated, non-syndromic Port-wine stain; data suggest that GNAQ (显示 GNAQ ELISA试剂盒) is the main genetic determinant in this condition. Moreover, isolated port-wine stains are distinct from capillary malformations seen in RASA1 disorders.

  9. Data showed that hypoxia regulated the expression of miR (显示 MLXIP ELISA试剂盒)-182 and RASA1 to promote HCC (显示 FAM126A ELISA试剂盒) angiogenesis.

  10. p120RasGAP shields Akt (显示 AKT1 ELISA试剂盒) from deactivating phosphatases in FGF1 (显示 FGF1 ELISA试剂盒) signaling, but loses this ability once cleaved by caspase-3 (显示 CASP3 ELISA试剂盒).

Cow (Bovine) RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) interaction partners

  1. The data suggest that nitrosylation of H-Ras (显示 HRAS ELISA试剂盒) rearranges the adsorptive potential and intrinsic GTPase (显示 RACGAP1 ELISA试剂盒) activity of H-Ras (显示 HRAS ELISA试剂盒) through modification of C-terminal cysteines of molecule.

Mouse (Murine) RAS P21 Protein Activator (GTPase Activating Protein) 1 (RASA1) interaction partners

  1. RASA1 catalytic activity is essential for the function and development of lymphatic vessel valves.

  2. These results indicate that the caspase-3 (显示 CASP3 ELISA试剂盒)/p120 RasGAP stress-sensing module impacts on carcinogen-induced liver cancer incidence but not sufficiently so as to affect overall survival.

  3. Double-deficient RASA1-neurofibromin 1 (显示 NF1 ELISA试剂盒) mice developed T cell acute lymphoblastic leukemia/lymphoma, which originated at an early point in T cell development and was dependent on activating mutations in the Notch1 (显示 NOTCH1 ELISA试剂盒) gene.

  4. Rasa1 may have a role in pathogenesis of capillary malformation-arteriovenous malformation in a mouse model

  5. Regulation of Rasa1 translation by miR (显示 MLXIP ELISA试剂盒)-132 was seen in severed axons, demonstrating local function within the axon.

  6. RASA1 mutation is responsible for the aberrant lymphatic architecture and functional abnormalities, as visualized in the PKWS subject and in the animal model.

  7. MicroRNA-31 activates the RAS pathway and functions as an oncogenic MicroRNA by repressing RAS p21 GTPase activating protein 1 (RASA1)

  8. 14-3-3 (显示 YWHAQ ELISA试剂盒) negatively regulates the RGC downstream of the PI3-kinase (显示 PIK3CA ELISA试剂盒)/Akt (显示 AKT1 ELISA试剂盒) signaling pathway

  9. Caspase-3 (显示 CASP3 ELISA试剂盒) is a stress intensity sensor that controls cell fate by either initiating a RasGAP cleavage-dependent cell resistance program or a cell suicide response mediated by akt (显示 AKT1 ELISA试剂盒).

  10. Data reveal a role for RASA1 as a physiological negative regulator of lymphatic endothelial cell growth that maintains the lymphatic vasculature in a quiescent functional state through its ability to inhibit Ras signal transduction.

RASA1 抗原简介

Antigen Summary

The protein encoded by this gene is located in the cytoplasm and is part of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. Mutations leading to changes in the binding sites of either protein are associated with basal cell carcinomas. Mutations also have been associated with hereditary capillary malformations (CM) with or without arteriovenous malformations (AVM) and Parkes Weber syndrome. Alternative splicing results in two isoforms where the shorter isoform, lacking the N-terminal hydrophobic region but retaining the same activity, appears to be abundantly expressed in placental but not adult tissues.

Alternative names and synonyms associated with RASA1

  • vacuolar peduncle (vap) Elisa Kit
  • RAS p21 protein activator (GTPase activating protein) 1 (RASA1) Elisa Kit
  • RAS p21 protein activator (GTPase activating protein) 1 (Rasa1) Elisa Kit
  • RAS p21 protein activator 1 (Rasa1) Elisa Kit
  • CG9209 Elisa Kit
  • CM-AVM Elisa Kit
  • CMAVM Elisa Kit
  • D-RasGAP Elisa Kit
  • Dmel\\CG9209 Elisa Kit
  • Gap Elisa Kit
  • GAPX Elisa Kit
  • p120GAP Elisa Kit
  • p120RASGAP Elisa Kit
  • PKWS Elisa Kit
  • RAS-GAP Elisa Kit
  • Rasa Elisa Kit
  • RASGAP Elisa Kit

Protein level used designations for RASA1

CG9209-PA , CG9209-PB , CG9209-PC , CG9209-PD , Ras GTPase-activating protein , vacuolar peduncule , vacuolar pedunculi , vap-PA , vap-PB , vap-PC , vap-PD , ras GTPase-activating protein 1 , triphosphatase-activating protein , GAP , GTPase-activating protein , RAS p21 protein activator (GTPase activating protein RAS p21) , p120GAP , rasGAP , RAS p21 protein activator 1 , p120-rasGAP

32569 Drosophila melanogaster
5921 Homo sapiens
282032 Bos taurus
25676 Rattus norvegicus
427327 Gallus gallus
479158 Canis lupus familiaris
100627579 Sus scrofa
218397 Mus musculus
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