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Mouse (Murine) CCL21 ELISA Kit for Sandwich ELISA - ABIN625110
Said, Frierson, Sanchez-Carbayo, Brekken, Theodorescu: Loss of SPARC in bladder cancer enhances carcinogenesis and progression. in The Journal of clinical investigation 2013
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plasmin (显示 PLG ELISA试剂盒) cleaves surface-bound CCL21 to release the C-terminal peptide responsible for CCL21 binding to glycosaminoglycans on the extracellular matrix and cell surfaces, thereby generating the soluble form.
the white pulp regions of ME7-infected spleens were smaller, and contained markedly diminished T zones, as compared to control spleens. Although lymphoid tissue inducer cells were not affected, the expression of both CCL19 (显示 CCL19 ELISA试剂盒) and CCL21 was decreased.
Taken together, these results suggest that SERCA2 (显示 ATP2A2 ELISA试剂盒) contributes to the migration of CCL21-activated Dendritic Cells as an important feature of the adaptive immune response and provide novel insights regarding the role of SERCA2 (显示 ATP2A2 ELISA试剂盒) in Dendritic Cells functions.
An expanded lymphatic network is capable of enhanced chemoattractant CCL21 production, and lymphangiogenesis will facilitate initial lymph formation favoring increased clearance of fluid in situations of augmented fluid filtration.
Results provide evidence for an association between an increase level of CCL21 and IP-10 (显示 CXCL10 ELISA试剂盒) in the blood and pulmonary involvement in systemic lupus erythematosus patients.
Gata1 (显示 GATA1 ELISA试剂盒)-KO(DC) DCs have reduced polysialic acid levels on their surface, which is a known determinant for the proper migration of DCs toward CCL21.
CCL21 and CXCL13 (显示 CXCL13 ELISA试剂盒) levels are increased in the minor salivary glands of patients with Sjogren's syndrome.
Deletion of this extended C-terminus reduces CCL21's affinity for heparin and transferring the CCL21 C-terminus to CCL19 (显示 CCL19 ELISA试剂盒) enhances heparin binding mainly through non-specific, electrostatic interactions
CCL21/CCR7 (显示 CCR7 ELISA试剂盒) interaction contributes to the time-dependent proliferation of PTC (显示 F9 ELISA试剂盒) cells by upregulating cyclin A (显示 CCNA2 ELISA试剂盒), cyclin B1 (显示 CCNB1 ELISA试剂盒) and cyclin-dependent kinase 1 (CDK1 (显示 CDK1 ELISA试剂盒)) expression via the extracellular signal-regulated kinase (ERK (显示 EPHB2 ELISA试剂盒)) pathway associated with iodine.
CCL21 can facilitate chemoresistance and stem cell property of colorectal cancer cells via the upregulation of P-gp (显示 ABCB4 ELISA试剂盒), Bmi-1 (显示 BMI1 ELISA试剂盒), Nanog (显示 NANOG ELISA试剂盒), and OCT-4 (显示 POU5F1 ELISA试剂盒) through AKT (显示 AKT1 ELISA试剂盒)/GSK-3beta (显示 GSK3b ELISA试剂盒)/Snail (显示 SNAI1 ELISA试剂盒) signals.
the CCR7 (显示 CCR7 ELISA试剂盒)/CCL21 signaling pathway leading to T lymphocyte migration on fibronectin (显示 FN1 ELISA试剂盒) is a beta1 integrin-dependent pathway involving transient ERK1/2 (显示 MAPK1/3 ELISA试剂盒) phosphorylation, which is modulated by PLCgamma1 (显示 PLCG1 ELISA试剂盒)
Data suggest that lymphotoxin (显示 LTB ELISA试剂盒)-dependent and -independent regulation of CC chemokine ligand 21-b and -c plays a role in balancing the central and peripheral immune responses between lymphoid and nonlymphoid tissues.
CCL21 and, to a lesser extent, CCL19 (显示 CCL19 ELISA试剂盒) play significant roles in the distinctive localization of marginal zone macrophages within the splenic marginal zone.
CCL21 and 5'-Nase may be involved in the interaction between infiltrating cells and lymphatic vessels to induce the functional changes of lymphatic endothelial cells during insulitic and diabetic development
CXCL9 (显示 CXCL9 ELISA试剂盒) has a role in graft rejection in the absence of CCL19 (显示 CCL19 ELISA试剂盒) and CCL21
T-cell defects in the nasal-associated lymphoid tissue of lymphotoxin (显示 LTB ELISA试剂盒)(-/-) mice can be attributed to the impaired expression of CCL21.
alpha-GalCer-loaded dendritic cells expressing tumor-associated antigen along with SLC can stimulate multiple subsets of effector cells to induce a potent therapeutic effect against peritoneally disseminated tumor cells.
following Leishmania donovani infection of mice, the migration of splenic DC is regulated by the CCR7 (显示 CCR7 ELISA试剂盒) ligands CCL19 (显示 CCL19 ELISA试剂盒)/CCL21
Results suggest that CCR7 (显示 CCR7 ELISA试剂盒)-positive fibrocytes infiltrate the kidney via CCL21-positive vessels, thereby contributing to the pathogenesis of renal fibrosis.
The presence of CCL21 during the in vitro stimulation of CD4 (显示 CD4 ELISA试剂盒)+ T cells with anti-CD3 (显示 CD3E ELISA试剂盒) plus anti-CD28 (显示 CD28 ELISA试剂盒) significantly enhanced in vitro AICD induction of the restimulated T cells, partially through enhancing expression of Fas ligand (显示 FASL ELISA试剂盒).
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19).
C-C motif chemokine 21
, CC chemokine ligand 21
, putative CCL21 chemokine
, small inducible cytokine A21
, small inducible cytokine A24
, Efficient Chemoattractant for Lymphocytes
, beta chemokine exodus-2
, secondary lymphoid tissue chemokine
, small inducible cytokine subfamily A (Cys-Cys), member 21
, chemokine CCL21/6CKINE
, small-inducible cytokine A21
, C-C motif chemokine 21b
, C-C motif chemokine 21c
, Small-inducible cytokine A21b
, beta-chemokine exodus-2
, small inducible cytokine A21c
, small-inducible cytokine A21c
, thymus-derived chemotactic agent 4