MMP7 蛋白 (MMP7)产品概述

Full name:
Matrix Metallopeptidase 7 (Matrilysin, Uterine) 蛋白 (MMP7)
在www.antibodies-online.cn可供33 Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7) 蛋白的10不同的供货商。 再加上,我们可以发MMP7 抗体 (258)MMP7 试剂盒 (115)和数多这个蛋白质的别的产品。 总共418 MMP7产品已列进来了。
别名:
LOC727698, MAT, Matrilysin, MMP-7, MMP7, MPMM, MPSL1, PUMP-1
列出全部蛋白 基因 基因ID UniProt
MMP7 17393  
MMP7 25335 P50280
MMP7 4316 P09237

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引用最多的MMP7 蛋白

  1. Human MMP7 Protein expressed in Human Cells - ABIN2002495 : Nagase, Woessner: Matrix metalloproteinases. in The Journal of biological chemistry 1999 (PubMed)
    Show all 4 references for 2002495

  2. Human MMP7 Protein expressed in Escherichia coli (E. coli) - ABIN1047364 : Muller, Quantin, Gesnel, Millon-Collard, Abecassis, Breathnach: The collagenase gene family in humans consists of at least four members. in The Biochemical journal 1988 (PubMed)
    Show all 2 references for 1047364

  3. Human MMP7 Protein expressed in Wheat germ - ABIN1311088 : Broussard, Kim, Wiley, Marquez, Annis, Pritchard, Disis: Identification of putative immunologic targets for colon cancer prevention based on conserved gene upregulation from preinvasive to malignant lesions. in Cancer prevention research (Philadelphia, Pa.) 2013 (PubMed)

更多MMP7互动伙伴

Mouse (Murine) Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7) interaction partners

  1. MMP7 shedding of syndecan-1 (显示 SDC1 蛋白)/CXCL1 (显示 CXCL1 蛋白) complexes functions as a checkpoint that restricts neutrophil activation at sites of epithelial injury.

  2. MMP7 exerts a restrictive role on H. pylori-induced gastric injury and the development of premalignant lesions by suppressing M1 macrophage polarization.

  3. absence of MMP7 protects mice from LPS (显示 TLR4 蛋白)-induced intestinal permeability and lethality.

  4. regulator of beta-catenin (显示 CTNNB1 蛋白) function in injured lung epithelium

  5. Angiotensin II suppresses RECK (显示 RECK 蛋白), but induces matrix metalloproteinases both in vivo and in vitro.

  6. MMP7 regulated ciliated cell formation.

  7. SPARC (显示 SPARC 蛋白) suppresses angiogenesis of gastric cancer by down-regulating the expression of VEGF (显示 VEGFA 蛋白) and MMP-7

  8. Protein expression levels of MMP-7, MMP-14 and ERK1/2 phosphorylation level were all elevated with the increasing pathological grades in brain glioma tissues.

  9. levels of renal MMP-7 correlate with Wnt (显示 WNT2 蛋白)/beta-catenin (显示 CTNNB1 蛋白) activity.

  10. STAT3 (显示 STAT3 蛋白) plays an important role in regulation of tumor growth, invasion, and angiogenesis, which could be act by reducing MMP-7 expression in pancreatic cancer cells.

Human Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7) interaction partners

  1. We conclude that in the resected esophageal cancer an increased mRNA expression of MMP-7, MMP-10 (显示 MMP10 蛋白) and TIMP-1 (显示 TIMP1 蛋白) correlated with clinicopathologic features. We suggest that these genes may play a role during progression of the disease MMP-10 (显示 MMP10 蛋白), MMP-7, TIMP-1 (显示 TIMP1 蛋白), TIMP-2 (显示 TIMP2 蛋白) were overexpressed in 73%, 85%, 55% and 42% of esophageal cancer samples, respectively.

  2. plasma concentrations of MMP-7, MMP-8 (显示 MMP8 蛋白), -9 and TIMP-1 (显示 TIMP1 蛋白) within 96 h from the onset of acute pancreatitis symptoms are elevated in acute pancreatitis patients compared with healthy controls

  3. ZnCo-heterobimetallic analog of cdMMP7 with Co(II) bound in the catalytic site was prepared and characterized. This study describes a well-characterized analog of MMP7 that is available for future inhibitor design efforts.

  4. data suggest that syndecan-2 (显示 SDC2 蛋白) induces extracellular shedding of E-cadherin (显示 CDH1 蛋白) and supports the acquisition of a fibroblast-like morphology by regulating MMP-7 expression in a colon cancer cell line

  5. There were no statistically significant differences in the distribution of MMP7 -181 A/G and MMP12 (显示 MMP12 蛋白) -82 A/G genotype, allele, or haplotype frequencies between IRSA patients and controls, as well as patients' primary and secondary idiopathic recurrent spontaneous abortion

  6. No significant differences were found between MMP-7 A-181G, C-115T, and TIMP-2 (显示 TIMP2 蛋白) G-418C polymorphism and coronary artery disease and myocardial infarction in a Turkish population.

  7. In summary, our study demonstrates that IL-7 (显示 IL7 蛋白)/IL-7R axis promotes the invasion and migration of prostate cancer cells, through activation of AKT (显示 AKT1 蛋白)/NF-kappaB (显示 NFKB1 蛋白) pathway and upregulation of MMP-3 (显示 MMP3 蛋白) and MMP-7 expression

  8. MMP-7 is a stable neutral hydrophilic secreted protein, and it may play a vital role in the invasion and metastasis of cancer cells.

  9. MMP-7 expression is regulated by SOX18 (显示 SOX18 蛋白) in prostate cancer.

  10. The concomitant presence of both MMP-2 (显示 MMP2 蛋白) C and MMP-7 G alleles was associated with 1.82-fold increased risk of multiple sclerosis.

蛋白简介MMP7

蛋白简介

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.

Alternative names and synonyms associated with MMP7

  • matrilysin-like (LOC100357971)
  • matrix metallopeptidase 7 (Mmp7)
  • matrix metallopeptidase 7 (matrilysin, uterine) (MMP7)
  • matrix metallopeptidase 7 (matrilysin, uterine) (Mmp7)
  • PUMP-1 (LOC727698)
  • LOC727698 蛋白
  • MAT 蛋白
  • Matrilysin 蛋白
  • MMP-7 蛋白
  • MMP7 蛋白
  • MPMM 蛋白
  • MPSL1 蛋白
  • PUMP-1 蛋白

Protein level used designations for MMP7

MMP-7 , matrilysin , matrilysin, uterine , matrin , matrix metalloproteinase 7 , matrix metalloproteinase-7 , pump-1 protease , uterine metalloproteinase , Matrix metalloproteinase 7 (matrilysin) , matrix metalloproteinase 7 (matrilysin, uterine) , uterine matrilysin , matrilysin-related protein

GENE ID SPECIES
100357971 Oryctolagus cuniculus
17393 Mus musculus
25335 Rattus norvegicus
4316 Homo sapiens
286794 Bos taurus
100727130 Cavia porcellus
397411 Sus scrofa
489432 Canis lupus familiaris
418983 Gallus gallus
100192317 Ovis aries
727698 Felis catus
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