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Human NCF1 ELISA Kit for Sandwich ELISA - ABIN418361
Vij, Hardej: Alterations in antioxidant/oxidant gene expression and proteins following treatment of transformed and normal colon cells with tellurium compounds. in Environmental toxicology and pharmacology 2016
Decreased and increased copy numbers of NCF1 predispose to and protect against SLE.
Lysophosphatidylcholines prime polymorphonuclear neutrophil through Hck (显示 HCK ELISA试剂盒)-dependent activation of PKCdelta (显示 PKCd ELISA试剂盒), which stimulates PKCgamma (显示 PRKCG ELISA试剂盒), resulting in translocation of phosphorylated p47(phox).
There was an increased frequency of the NCF1-339 T allele in patients with systemic lupus erythematosus. The NCF1-339 T allele reduced extracellular ROS (显示 ROS1 ELISA试剂盒) production in neutrophils and led to an increase expression of type 1 interferon (显示 IFNA ELISA试剂盒)-regulated genes.
Skeletal muscle protein expression of the NADPH oxidase (显示 NOX1 ELISA试剂盒) subunits p22(phox (显示 CYBA ELISA试剂盒)), p47(phox), and p67(phox (显示 NCF2 ELISA试剂盒)) was increased in obese relative to lean subjects, where p22(phox (显示 CYBA ELISA试剂盒)) and p67(phox (显示 NCF2 ELISA试剂盒)) expression was attenuated by exercise training in obese subjects.
A novel role for Spns2 and S1P1 (显示 S1PR1 ELISA试剂盒)&2 in the activation of p47(phox) and production of reactive oxygen species involved in hyperoxia-mediated lung injury.
Study provides evidence for a novel PKC-zeta (显示 PRKCZ ELISA试剂盒) to p47phox interaction that is required for cell transformation from blebbishields and ROS (显示 ROS1 ELISA试剂盒) production in cancer cells.
Overexpression of p47phox is associated with increased migration/metastasis rate in melanoma.
A rare mutation in NCF1 encoding p47phox of the leukocyte NADPH oxidase (显示 NOX1 ELISA试剂盒) causes lack of superoxide generation, leads to chronic granulomatous disease and was recently (1200-2300 years ago) introduced into the Kavkazi Jewish population
Data show that diphenylene iodonium (DPI) and apocynin can reduce hyperoxia-induced reactive oxygen species (ROS) production by decreasing the translocation and level of NADPH Oxidase p47phox.
increased levels of gp91phox (显示 CYBB ELISA试剂盒), p47phox and p22phox (显示 CYBA ELISA试剂盒) likely account for the interferon-gamma (显示 IFNG ELISA试剂盒) mediated enhancement of dimethyl sulfoxide-induced Nox2 (显示 CYBB ELISA试剂盒) activity.
Mice bearing point mutation in the Ncf1-gene develop fewer osteoclasts after ovariectomy (ovx) than wild-type mice. However, irrespective of genotype, bone mineral density decreases after ovx, indicating that a compensatory mechanism retains bone degradation after ovx.
The authors demonstrated a significant role of the host NADPH oxidase (显示 NOX1 ELISA试剂盒) in promoting chronic inflammatory pathology in the oviduct following chlamydial infection.
data partly explains the discrepancy of the phenotypes reported earlier utilizing the Ncf1m1J mice or Ncf1 knockout mice.
Data (including data from studies in transgenic mice) suggest that ability to generate Ncf1-derived superoxide, specifically in CD4 (显示 CD4 ELISA试剂盒)-positive T-lymphocytes, is key for development of autoimmune responses in type 1 diabetes.
The Park7 (显示 PARK7 ELISA试剂盒) binds to p47(phox), a subunit of the NADPH oxidase (显示 NOX1 ELISA试剂盒), to promote NADPH oxidase (显示 NOX1 ELISA试剂盒)-dependent production of ROS (显示 ROS1 ELISA试剂盒).
p47(phox)-dependent NADPH oxidases are a major glomerular source of reactive oxygen species, contributing to kidney injury
p47phox mRNA expression was increased in diet-induced obese (DIO) mice. p47phox suppresses collateral vessel growth after femoral artery ligation in DIO mice.
These findings suggest that a p47(phox)-dependent NAD(P)H (显示 NQO1 ELISA试剂盒) oxidase mediates the increase in diaphragm oxidants and contractile dysfunction in chronic heart failure.
The present study provides evidence that augmented EGFRtk impairs vascular function by NADPH oxidase (显示 NOX1 ELISA试剂盒)-dependent mechanism. Therefore, EGFRtk and oxidative stress should be potential targets to treat vascular dysfunction in TD2.
NOX2 (显示 CYBB ELISA试剂盒)/ROS (显示 ROS1 ELISA试剂盒) activity in macrophages signals the development of antigen-specific CD8 (显示 CD8A ELISA试剂盒)(+)T cell response.
Differential Roles of Protein Complexes NOX1-NOXO1 and NOX2-p47phox in Mediating Endothelial Redox Responses to Oscillatory and Unidirectional Laminar Shear Stress.
two novel splice variants designed as NCF1-TV1 (retained intron 6) and NCF1-TV2 (retained part of intron 8)encoding two putative truncated proteins (239AA and 283AA). Two splice variants were up-regulated in the mastitis-infected cows' mammary tissues, blood and neutrophils compared with these of healthy cows.
A p47(phox) and Src kinase (显示 CSK ELISA试剂盒) activation of peroxide production by Nox2 (显示 CYBB ELISA试剂盒) appears to be an important contributor to vascular contractile mechanisms mediated through activation of protein kinase C (显示 PKC ELISA试剂盒).
Angiotensin II inhibits the Na+/K+ pump via PKC (显示 PKC ELISA试剂盒)-dependent activation of NADPH oxidase (显示 NOX1 ELISA试剂盒) subunits.
The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disease.
47 kDa autosomal chronic granulomatous disease protein
, 47 kDa neutrophil oxidase factor
, NADPH oxidase organizer 2
, SH3 and PX domain-containing protein 1A
, neutrophil NADPH oxidase factor 1
, neutrophil cytosol factor 1
, neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1)
, nox organizer 2
, nox-organizing protein 2
, NADPH oxidase subunit (47 kD)
, NADPH oxidase subunit (47kDa)
, phagocyte oxidase 47 kDa
, neutrophil cytosolic factor 1 (47kDa, chronic granulomatous disease, autosomal 1)
, NADPH oxidase p47-phox
, predicted neutrophil cytosolic factor 1