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Rat (Rattus) FOXO1 ELISA Kit for Sandwich ELISA - ABIN431805
Akbulut, Aktas, Akbulut: The role of melatonin, sirtuin2 and FoXO1 transcription factor in the aging process of colon in male rats. in Biogerontology 2015
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MicroRNA-183-96-182 cluster regulates bovine granulosa cell function by targeting FOXO1 gene.
downregulation of SIRT1 (显示 SIRT1 ELISA试剂盒) and FoxO1 were observed in the backfat tissue of Lilu cattle with increasing age
FOXO (显示 FOXO3 ELISA试剂盒) is a key regulator of ROS (显示 ROS1 ELISA试剂盒)-induced apoptosis in mammalian cells.
Protein kinase A-alpha directly phosphorylates FoxO1 in vascular endothelial cells to regulate expression of vascular cellular adhesion molecule (显示 NCAM1 ELISA试剂盒)-1 mRNA.
The results demonstrate pathways through which two different mediators, TNF-alpha (显示 TNF ELISA试剂盒) and an advanced glycation endproduct, can induce pericyte apoptosis through activation of the transcription factor FOXO1.
These data suggest that high doses of insulin (显示 INS ELISA试剂盒) downregulate apoA-I (显示 APOA1 ELISA试剂盒) gene expression in HepG2 cells through redistribution of FOXO1/LXRbeta (显示 NR1H2 ELISA试剂盒) complex, FOXA2 (显示 FOXA2 ELISA试剂盒), and LXRalpha (显示 NR1H3 ELISA试剂盒) on hepatic enhancer of apoA-I (显示 APOA1 ELISA试剂盒) gene.
FOXO1 inhibits the self-renewal capacity of gastric cancer cells through interaction with LGR5 (显示 LGR5 ELISA试剂盒).
elevated expression of microRNA-873 facilitates Th17 differentiation by targeting forkhead box O1 (Foxo1) in the pathogenesis of systemic lupus erythematosus
Results provide a mechanistic understanding for the observation that loss of IGF-1R (显示 IGF1R ELISA试剂盒) expression decreases tamoxifen sensitivity resulting from reduced FoxO1 expression in breast cancer cells.
Low FOXO1 expression is associated with invasive oral cancer.
TLR4 (显示 TLR4 ELISA试剂盒) and C5aR (显示 C5AR1 ELISA试剂盒) crosstalk in dendritic cells induces a core regulatory network of RSK2 (显示 RPS6KA3 ELISA试剂盒), PI3Kbeta, SGK1 (显示 SGK1 ELISA试剂盒), and FOXO (显示 FOXO3 ELISA试剂盒) transcription factors.
The data suggest that pre-B cells are endowed with a protective mechanism that reduces the risk for aberrant recombinations and chromosomal translocations when exposed to DNA damage, involving the ATM (显示 ATM ELISA试剂盒)-dependent regulation of FOXO1 binding to the Erag enhancer region.
expression of Bim (显示 BCL2L11 ELISA试剂盒) is mediated by FoxO1 and indirectly downregulated by thyroid hormone/thyroid hormone (显示 PTH ELISA试剂盒) receptor (显示 THRA ELISA试剂盒), leading to chemotherapy resistance and doxorubicin-promoted metastasis of hepatoma cells.
this study shows that FoxO1 plays an important role in regulating asbestos-induced apoptosis in T cells
increased FOXO1 represents a critical mechanism driving aberrant self-renewal in preleukemic cells expressing the t(8;21)-associated oncogene AML1 (显示 RUNX1 ELISA试剂盒)-ETO (显示 RUNX1T1 ELISA试剂盒).
These results indicate glycine enhances muscle protein mass under an inflammatory condition. The beneficial roles of glycine on the muscle are closely associated with maintaining Akt (显示 AKT1 ELISA试剂盒)-mTOR (显示 FRAP1 ELISA试剂盒)-FOXO1 signaling and suppressing the activation of TLR4 (显示 TLR4 ELISA试剂盒) and/or NOD2 (显示 NOD2 ELISA试剂盒) signaling pathways.
let-7g induces porcine granulosa cells apoptosis by inhibiting the MAP3K1 (显示 MAP3K1 ELISA试剂盒) gene, which promotes FoxO1 expression and dephosphorylation with nuclear accumulation.
inhibition of FoxO1 expression level caused by miR (显示 MYLIP ELISA试剂盒)-15a/b over-expression had a positive effect on adipogenesis. Thus, we conclude that miR (显示 MYLIP ELISA试剂盒)-15a/b promote adipogenesis in porcine pre-adipocyte via repressing FoxO1
Results show that FoxO1 likely regulates MyHC I (显示 MYH7 ELISA试剂盒) negatively and MyHC IIx and MyHC IIb (显示 MYH4 ELISA试剂盒) positively and may play a pivotal role in the determination of muscle fiber type.
Data suggest forkhead box protein O1 (FoxO1) involvement in the regulation of TNF-related apoptosis-inducing ligand TRAIL (显示 TNFSF10 ELISA试剂盒) and Fas ligand FasL (显示 FASL ELISA试剂盒) expression during follicular atresia.
Data show that IL-4 (显示 IL4 ELISA试剂盒) induces upregulation of the junction protein claudin-5 (显示 CLDN5 ELISA试剂盒) in endothelial cells (ECs) through activation of Jak (显示 JAK3 ELISA试剂盒)/STAT6 (显示 STAT6 ELISA试剂盒) and phosphorylation and translocation of FoxO1 from the nucleus to the cytoplasm.
FoxO1 and C/EBPb (显示 CEBPB ELISA试剂盒) regulate preadipocyte adipogenesis possibly through C/EBPb (显示 CEBPB ELISA试剂盒)-> FoxO1-> C/EBPb (显示 CEBPB ELISA试剂盒) feedback regulatory loop and FoxO1-C/EBPb (显示 CEBPB ELISA试剂盒) protein complex.
FoxO1 delays and negatively regulates the porcine myoblast differentiation. It may also play a critical role in muscle fiber-type specification through the inhibition of myogenic regulation factors.
concluded that PI 3 (显示 PI3 ELISA试剂盒)-kinase and Akt (显示 AKT1 ELISA试剂盒) are activated after renal ischemia/reperfusion and that Akt (显示 AKT1 ELISA试剂盒) phosphorylation leads to phosphorylation of FKHR and FKHRL1 (显示 FOXO3 ELISA试剂盒), which may affect epithelial cell fate in acute renal failure.
FoxO1a can regulate p27kip nuclear localization
data reveal apelin (显示 APLN ELISA试剂盒) as a novel regulator of FoxO1 in cardiac cells and provide evidence for the potential of apelin (显示 APLN ELISA试剂盒)-13 in prevention of apoptosis and mitochondrial damage in conditions combining I/R injury and obesity.
Besides, both in vivo and in votro studies suggested that K145 stimulated insulin (显示 INS ELISA试剂盒) dependent Akt (显示 AKT1 ELISA试剂盒) phosphorylation and subsequently activates FoxO1 phosphorylation therefore inhibited gluconeogenetic genes expression including PEPCK (显示 PEPCK ELISA试剂盒) and G6pase (显示 G6PC ELISA试剂盒). Our study figures out a potential extent increase the value of developing K145 as therapeutic candidate for diabetes.
Ikaros (显示 IKZF1 ELISA试剂盒) is a transcriptional regulator required for maintaining levels of Foxo1 gene expression in naive T-cells.
this study shows that Foxo1 is a positive regulatory factor for the proliferation and activity of Treg cells
Data show that Fos-Related Antigen-2 (Fra-2 (显示 FOSL2 ELISA试剂盒)) is a key upstream regulator of forkhead box O1 (Foxo1) and interferon regulatory factor 4 (Irf4 (显示 IRF4 ELISA试剂盒)) expression and influences proliferation and differentiation of B cells at multiple stages.
ANG2 (显示 ANGPT2 ELISA试剂盒) activation of Tie2 (显示 TEK ELISA试剂盒) supports stable enlargement of normal nonleaky vessels, but reduction of Tie1 (显示 TIE1 ELISA试剂盒) in inflammation leads to ANG2 (显示 ANGPT2 ELISA试剂盒) antagonism of Tie2 (显示 TEK ELISA试剂盒) and initiates a positive feedback loop wherein FOXO1-driven ANG2 (显示 ANGPT2 ELISA试剂盒) expression promotes vascular remodeling and leakage
Link between the antioxidative activity of FoxO1 with PINK1/Parkin (显示 PARK2 ELISA试剂盒)-induced mitophagy, indicating a novel role of FoxO1 in diabetic nephropathy.
Pyruvate dehydrogenase kinase 4 (显示 PDK4 ELISA试剂盒) is a direct transcriptional target of FoxO1 in the heart. FoxO1 directly regulates Pdk4 (显示 PDK4 ELISA试剂盒) transcription in the heart, thereby controlling PDH (显示 PDP ELISA试剂盒) activity and subsequent glucose oxidation rates.
the overlap of IR and IGF1R (显示 IGF1R ELISA试剂盒) signaling is critical to the regulation of muscle protein turnover, and this regulation depends on suppression of FoxO (显示 FOXO3 ELISA试剂盒)-regulated, autophagy-mediated protein degradation
These results suggest that the LKB1 (显示 STK11 ELISA试剂盒)-AMPK (显示 PRKAA1 ELISA试剂盒)-FoxO1 signaling pathway is a critical mediator of the antioxidant properties of H2, further supporting the idea that H2 acts as a signaling molecule to serve various physiological functions.
FoxO1 translocation to the nucleus, and the increase in FoxO1 DNA binding activity in X. laevis liver strongly correlate with the up-regulation of manganese-dependent superoxide dismutase (显示 SOD1 ELISA试剂盒) and catalase (显示 CAT ELISA试剂盒) mRNA and protein levels in this organ.
These results indicate that miR (显示 MYLIP ELISA试剂盒)-182 functions as a FoxO1 inhibitor to antagonize osteoblast proliferation and differentiation, with a subsequent negative effect on osteogenesis.
gas6 (显示 GAS6 ELISA试剂盒) protects endothelial cells from apoptosis by a mechanism that involves PI3K-Akt (显示 AKT1 ELISA试剂盒)-dependent inactivation of FOXO1a.
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined\; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.
forkhead box protein O1
, forkhead box protein O1A
, forkhead, Drosophila, homolog of, in rhabdomyosarcoma
, forkhead box O1A
, forkhead box protein O1-A
, fox family transcription factor FoxO1a.1
, foxhead box protein O1-A
, Forkhead box protein O1A
, Forkhead in rhabdomyosarcoma
, forkhead box O1A (rhabdomyosarcoma)
, forkhead box O1a
, forkhead in rhabdomyosarcoma
, forkhead protein 1
, forkhead/winged helix transcription factor FOXO1a
, forkhead box O1
, forkhead box protein O1-like