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Rat (Rattus) FOXO1 ELISA Kit for Sandwich ELISA - ABIN431805
Akbulut, Aktas, Akbulut: The role of melatonin, sirtuin2 and FoXO1 transcription factor in the aging process of colon in male rats. in Biogerontology 2015
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miR (显示 MLXIP ELISA试剂盒)-181a2/181b2 prominently dampened cell-cycle progression, suppressed cell growth, and promoted apoptosis of tumor cells in vitro They also effectively impeded tumor formation and growth in vivo miR (显示 MLXIP ELISA试剂盒)-181a2/181b2 exert the tumor suppressor ability by depressing the direct target PIK3R3 (p55gamma) and consequently modulating the PIK3R3/Akt (显示 AKT1 ELISA试剂盒)/FoxO (显示 FOXO3 ELISA试剂盒) signaling pathway
A high extent more than 25% of BRAF (显示 BRAF ELISA试剂盒)(V600E) alleles may be associated with disease outcome in PTC (显示 F9 ELISA试剂盒) patients.
Low FOXO1 expression is associated with hepatocellular carcinoma.
Combined treatment with gamma-irradiation (gammaIR) and a dual PI3K (显示 PIK3CA ELISA试剂盒)/mTOR (显示 FRAP1 ELISA试剂盒) inhibitor causes loss of stemness and of FoxO1/3 proteins in p53 (显示 TP53 ELISA试剂盒)-proficient glioblastoma multiforme stem cells (GBM-SCs (显示 TWIST1 ELISA试剂盒)).
AQP9 (显示 AQP7 ELISA试剂盒) overexpression decreased the protein levels of phosphatidylinositol-3-kinase (PI3K (显示 PIK3CA ELISA试剂盒)), leading to reduced phosphorylation of Akt (显示 AKT1 ELISA试剂盒), and subsequently the protein levels of forkhead box protein O1 (FOXO1) were increased.
High glucose triggers IL-1beta (显示 IL1B ELISA试剂盒) synthesis in retinal endothelial cells. The produced IL-1beta (显示 IL1B ELISA试剂盒) induces increased FoxO1 expression, and interacts with the IL-1 (显示 IL1A ELISA试剂盒) receptor to activate MAPK (显示 MAPK1 ELISA试剂盒) signaling, thereby inducing IL-1beta (显示 IL1B ELISA试剂盒) autostimulation.
Results identified FOXO1 as a downstream effector of DKK3 that may play a role in blocking adrenocortical dedifferentiation.
Foxo1 signaling contributes to maintainance and exacerbation inflammation and insulin (显示 INS ELISA试剂盒) resistance in polycystic ovary syndrome macrophages.
presence of a new non-consensus FoxO1 binding site on the G6PC1 (显示 G6PC ELISA试剂盒) promoter that overlaps the CRE, suggesting a mutual exclusion mechanism for FoxO1 and CREB (显示 CREB1 ELISA试剂盒) binding at the G6PC1 (显示 G6PC ELISA试剂盒) promoter
These results indicate that miR (显示 MYLIP ELISA试剂盒)-182 functions as a FoxO1 inhibitor to antagonize osteoblast proliferation and differentiation, with a subsequent negative effect on osteogenesis.
gas6 (显示 GAS6 ELISA试剂盒) protects endothelial cells from apoptosis by a mechanism that involves PI3K-Akt (显示 AKT1 ELISA试剂盒)-dependent inactivation of FOXO1a.
we found that in db/db (显示 LEPR ELISA试剂盒) VSMC, the occupancy in promoter regions of inflammatory genes by FOXO1 was reduced.miR-135a increased the inflammatory responses of VSMC involved in complications of vascular diseases by downregulating the expression of FOXO1.
Trehalose may rescue against insulin (显示 INS ELISA试剂盒) resistance-induced myocardial contractile defect and apoptosis, via autophagy associated with dephosphorylation of p38 MAPK (显示 MAPK14 ELISA试剂盒) and Foxo1 without affecting phosphorylation of Akt (显示 AKT1 ELISA试剂盒).
FoxO1 is a key mediator involved in glucose homeostasis and indicate that 1,25(OH)2D3 improves glucose metabolism and bone development
Data show that the mitochondrial enriched GCN5 (显示 KAT2A ELISA试剂盒)-like 1 protein (GCN5L1 (显示 BLOC1S1 ELISA试剂盒)) controls hepatic glucose production by regulating FoxO1 protein levels.
Setdb1 (显示 SETDB1 ELISA试剂盒) regulates PTEN/AKT (显示 AKT1 ELISA试剂盒)/FOXO1 pathway to inhibit Spermatogonial stem cells apoptosis.
These findings indicate that IGF-II reduces PGC-1alpha (显示 PPARGC1A ELISA试剂盒) expression in skeletal muscle cells through a mechanism involving PI3K-Akt (显示 AKT1 ELISA试剂盒)-FoxO1 but not p38 MAPK (显示 MAPK14 ELISA试剂盒) or Erk1/2 (显示 MAPK1/3 ELISA试剂盒) MAPK (显示 MAPK1 ELISA试剂盒) pathways.
a critical role for FOXO (显示 FOXO3 ELISA试剂盒) transcription factors in mediating these proliferative versus apoptotic fates
L. donovani triggered AKT (显示 AKT1 ELISA试剂盒) activation to regulate GSK-3beta (显示 GSK3b ELISA试剂盒)/beta-catenin (显示 CTNNB1 ELISA试剂盒)/FOXO-1 axis.
The data suggest autocrine nitric oxide/atrial natriuretic peptide (显示 NPPA ELISA试剂盒)-induced activation of protein kinase (显示 CDK7 ELISA试剂盒) G type Ialpha/p-AKT (显示 AKT1 ELISA试剂盒)/p-FOXO1 promotes survival and proliferation in pancreatic beta-cells.
Myocardial ischemia is associated with downregulation and posttranslational modification of cardiac FoxO1. In a mouse model of postischemic heart failure, posttranslational modulation of FoxO1 alters heart function involving collagen and protein metabolism.
These results indicate glycine enhances muscle protein mass under an inflammatory condition. The beneficial roles of glycine on the muscle are closely associated with maintaining Akt (显示 AKT1 ELISA试剂盒)-mTOR (显示 FRAP1 ELISA试剂盒)-FOXO1 signaling and suppressing the activation of TLR4 (显示 TLR4 ELISA试剂盒) and/or NOD2 (显示 NOD2 ELISA试剂盒) signaling pathways.
let-7g induces porcine granulosa cells apoptosis by inhibiting the MAP3K1 (显示 MAP3K1 ELISA试剂盒) gene, which promotes FoxO1 expression and dephosphorylation with nuclear accumulation.
inhibition of FoxO1 expression level caused by miR (显示 MYLIP ELISA试剂盒)-15a/b over-expression had a positive effect on adipogenesis. Thus, we conclude that miR (显示 MYLIP ELISA试剂盒)-15a/b promote adipogenesis in porcine pre-adipocyte via repressing FoxO1
Results show that FoxO1 likely regulates MyHC I (显示 MYH7 ELISA试剂盒) negatively and MyHC IIx and MyHC IIb (显示 MYH4 ELISA试剂盒) positively and may play a pivotal role in the determination of muscle fiber type.
Data suggest forkhead box protein O1 (FoxO1) involvement in the regulation of TNF-related apoptosis-inducing ligand TRAIL (显示 TNFSF10 ELISA试剂盒) and Fas ligand FasL (显示 FASL ELISA试剂盒) expression during follicular atresia.
Data show that IL-4 (显示 IL4 ELISA试剂盒) induces upregulation of the junction protein claudin-5 (显示 CLDN5 ELISA试剂盒) in endothelial cells (ECs) through activation of Jak (显示 JAK3 ELISA试剂盒)/STAT6 (显示 STAT6 ELISA试剂盒) and phosphorylation and translocation of FoxO1 from the nucleus to the cytoplasm.
FoxO1 and C/EBPb (显示 CEBPB ELISA试剂盒) regulate preadipocyte adipogenesis possibly through C/EBPb (显示 CEBPB ELISA试剂盒)-> FoxO1-> C/EBPb (显示 CEBPB ELISA试剂盒) feedback regulatory loop and FoxO1-C/EBPb (显示 CEBPB ELISA试剂盒) protein complex.
FoxO1 delays and negatively regulates the porcine myoblast differentiation. It may also play a critical role in muscle fiber-type specification through the inhibition of myogenic regulation factors.
concluded that PI 3 (显示 PI3 ELISA试剂盒)-kinase and Akt (显示 AKT1 ELISA试剂盒) are activated after renal ischemia/reperfusion and that Akt (显示 AKT1 ELISA试剂盒) phosphorylation leads to phosphorylation of FKHR and FKHRL1 (显示 FOXO3 ELISA试剂盒), which may affect epithelial cell fate in acute renal failure.
FoxO1a can regulate p27kip nuclear localization
MicroRNA-183-96-182 cluster regulates bovine granulosa cell function by targeting FOXO1 gene.
downregulation of SIRT1 (显示 SIRT1 ELISA试剂盒) and FoxO1 were observed in the backfat tissue of Lilu cattle with increasing age
FOXO (显示 FOXO3 ELISA试剂盒) is a key regulator of ROS (显示 ROS1 ELISA试剂盒)-induced apoptosis in mammalian cells.
Protein kinase A-alpha directly phosphorylates FoxO1 in vascular endothelial cells to regulate expression of vascular cellular adhesion molecule (显示 NCAM1 ELISA试剂盒)-1 mRNA.
The results demonstrate pathways through which two different mediators, TNF-alpha (显示 TNF ELISA试剂盒) and an advanced glycation endproduct, can induce pericyte apoptosis through activation of the transcription factor FOXO1.
FoxO1 translocation to the nucleus, and the increase in FoxO1 DNA binding activity in X. laevis liver strongly correlate with the up-regulation of manganese-dependent superoxide dismutase (显示 SOD1 ELISA试剂盒) and catalase (显示 CAT ELISA试剂盒) mRNA and protein levels in this organ.
This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined\; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.
forkhead box protein O1
, forkhead box protein O1A
, forkhead, Drosophila, homolog of, in rhabdomyosarcoma
, forkhead box O1A
, forkhead box protein O1-A
, fox family transcription factor FoxO1a.1
, foxhead box protein O1-A
, Forkhead box protein O1A
, Forkhead in rhabdomyosarcoma
, forkhead box O1A (rhabdomyosarcoma)
, forkhead box O1a
, forkhead in rhabdomyosarcoma
, forkhead protein 1
, forkhead/winged helix transcription factor FOXO1a
, forkhead box O1
, forkhead box protein O1-like