anti-AKT (AKT1) 抗体产品概述

Full name:
anti-V-Akt Murine Thymoma Viral Oncogene Homolog 1 抗体 (AKT1)
在www.antibodies-online.cn可供1284 V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) 抗体的45不同的供货商。 再加上,我们可以发AKT 试剂盒 (59)AKT 蛋白 (50)和数多这个蛋白质的别的产品。 总共1492 AKT产品已列进来了。
akt, akt-1, Akt/PKB, akt1, ATAKT1, CG4006, CWS6, D-Akt, dakt, dAKT/dPKB, dAkt/PKB, dakt1, DAKT1/PKB, Dmel\\CG4006, dPKB, DRAC-PK, DRAC-PK66, DRAC-PK85, F18A8.2, F18A8_2, K+ transporter 1, l(3)04226, l(3)89Bq, p-Akt, pAkt, PKB, PKB-ALPHA, PKB/Akt, PKB/dAKT, PKBalpha, POTASSIUM TRANSPORTER, PRKBA, Rac, RAC-ALPHA, RacPK, v-akt, v-akt1, xAct
列出全部抗体 基因 基因ID UniProt
AKT1 11651 P31750
AKT1 207 P31749
大鼠 AKT1 AKT1 24185 P47196



所有可销售的anti-AKT 抗体


引用最多的anti-AKT 抗体

  1. Human Polyclonal AKT Primary Antibody for EIA, IHC (p) - ABIN358075 : Bellacosa, Chan, Ahmed, Datta, Malstrom, Stokoe, McCormick, Feng, Tsichlis: Akt activation by growth factors is a multiple-step process: the role of the PH domain. in Oncogene 1998 (PubMed)
    Show all 4 references for 358075

  2. Human Polyclonal AKT Primary Antibody for DB - ABIN389509 : DeBusk, Hallahan, Lin: Akt is a major angiogenic mediator downstream of the Ang1/Tie2 signaling pathway. in Experimental cell research 2004 (PubMed)
    Show all 4 references for 389509

  3. Human Polyclonal AKT Primary Antibody for FACS, WB - ABIN652283 : Liao, Grobholz, Abel, Trojan, Michel, Angel, Mayer: Increase of AKT/PKB expression correlates with gleason pattern in human prostate cancer. in International journal of cancer. Journal international du cancer 2003 (PubMed)
    Show all 4 references for 652283

  4. Human Polyclonal AKT Primary Antibody for WB - ABIN389510 : Bourguignon, Singleton, Diedrich et al.: Hyaluronan-CD44 interaction with Rac1-dependent protein kinase N-gamma promotes phospholipase Cgamma1 activation, Ca(2+) signaling, and cortactin-cytoskeleton function leading to keratinocyte ... in The Journal of biological chemistry 2004 (PubMed)
    Show all 3 references for 389510

  5. Human Polyclonal AKT Primary Antibody for IF (p), IHC (p) - ABIN725195 : Xu, Huang, Xie, Lin, Guo, Zhuang, Lin, Zhou, Li, Huang, Wei, Man, Zhang: The expression of cytoglobin as a prognostic factor in gliomas: a retrospective analysis of 88 patients. in BMC cancer 2013 (PubMed)
    Show all 3 references for 725195

  6. Human Polyclonal AKT Primary Antibody for DB - ABIN650890 : Chen, Gomes, Monteiro, Wong, Wu, Ng, Karadedou, Millour, Ip, Cheung, Sunters, Chan, Lam, Khoo: Constitutively nuclear FOXO3a localization predicts poor survival and promotes Akt phosphorylation in breast cancer. in PLoS ONE 2010 (PubMed)

  7. Cow (Bovine) Polyclonal AKT Primary Antibody for WB - ABIN2792187 : Jones, Jakubowicz, Pitossi, Maurer, Hemmings: Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily. in Proceedings of the National Academy of Sciences of the United States of America 1991 (PubMed)


Fruit Fly (Drosophila melanogaster) V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. The metabolic defects of cycG (显示 CCNG1 抗体) mutant animals are abrogated by a concomitant loss of Wdb, CycG (显示 CCNG1 抗体) presumably influences Akt1 activity at the PP2A (显示 PPP2R2B 抗体) nexus; Well rounded (Wrd), another B' subunit of PP2A (显示 PPP2R2B 抗体) in Drosophila, binds CycG (显示 CCNG1 抗体) similar to Wdb, and that its loss ameliorates some, but not all, of the metabolic defects of cycG (显示 CCNG1 抗体) mutants.

  2. Our findings demonstrated that lovastatin restored LRRK2 (显示 LRRK2 抗体)-G2019S neurite degeneration by augmenting Akt/NRF2 (显示 NFE2L2 抗体) pathway and inhibiting downstream GSK3b (显示 GSK3b 抗体) activity, which decreased phospho-tau levels. We suggested that lovastatin is a potential disease-modifying agent for LRRK2 (显示 LRRK2 抗体)-G2019S parkinsonism.

  3. subtle manipulation of foxo (显示 FOXO 抗体) through Akt1 can enhance survival during adverse nutrient conditions in Drosophila.

  4. The developmental delay of these novel Akt1 hypomorphs results in a latent phenotype uncovered by generation of somatic clones

  5. these data show that Drosophila Trbl has a conserved role to bind Akt and block Akt-mediated insulin signaling, and implicate Trib proteins as novel sites of signaling pathway integration that link nutrient availability with cell growth and proliferation

  6. AKT1 and caspase-dependent regulation of Acn stability adjusts basal autophagy levels.

  7. Akt1 governs two critical elements of synapse development, neurotransmitter receptor (显示 GRIN1 抗体) localization, and postsynaptic membrane elaboration

  8. Tsc2 (显示 TSC2 抗体) mutants showed a dramatic decrease in the levels of phosphorylated Akt, and interestingly, Akt mutants phenocopied Tsc2 (显示 TSC2 抗体) mutants, leading to the hypothesis that Tsc2 (显示 TSC2 抗体) and Akt might work via the same genetic pathway to regulate synapse growth.

  9. Hippo signaling not only blocks cell division and promotes apoptosis, but also regulates cellular growth by inhibiting the Akt pathway activity.

  10. Regeneration of Drosophila sensory neuron axons and dendrites is regulated by the Akt pathway involving Pten (显示 PTEN 抗体) and microRNA bantam.

Arabidopsis thaliana V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. CIPK23 and AtKC1 exhibit distinct effects; however, they act synergistically and balance K(+) uptake/leakage to modulate AKT1-mediated low potassium responses in Arabidopsis.

  2. results suggest that NO decreases K(+) absorption by promoting the synthesis of vitamin B6 PLP (显示 FNTA 抗体), which further represses the activity of K(+) channel (显示 KCNC4 抗体) AKT1 in Arabidopsis.

  3. Examination of the athak5 atakt1 double mutant, revealing novel aspects of an uptake system as yet unidentified by genetic means.

  4. AKT1 is regulated by CIPK23 in guard cells and is involved in water stress responses.

  5. These findings provide further insights into the signaling network consisting of CBL (显示 CBL 抗体)-CIPK-PP2C interactions in the activation of the AKT1 channel.

  6. Electrophysiological results showed that AtKC1 inhibited the AKT1-mediated inward K(+) currents and negatively shifted the voltage dependence of AKT1 channels.

  7. AtHAK5 and AKT1 are vital for plant growth and development at low K+ concentrations.

  8. In the range between 0.01 and 0.05 mM K+ AtHAK5 and AtAKT1 are the only contributors to K+ acquisition. At higher K+ concentrations, unknown systems come into operation and participate together with AtAKT1 in low-affinity K+ uptake.

  9. CIPK23 directly phosphorylates the K+ transporter AKT1

  10. Data show that interacting calcium sensors (CBL1 and CBL9) together with CIPK23, but not either alone, activated the AKT1 channel in a Ca(2 (显示 CA2 抗体)+)-dependent manner, connecting the Ca(2 (显示 CA2 抗体)+) signal to K(+) uptake through activation of a K(+) channel (显示 KCNC4 抗体).

Mouse (Murine) V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. TSC1 (显示 TSC1 抗体)/TSC2 (显示 TSC2 抗体) complex upregulation of OPN (显示 SPP1 抗体) expression is mediated by transcription factor SOX9 (显示 SOX9 抗体) in an mTOR (显示 FRAP1 抗体)-independent manner. Moreover, ablation of OPN (显示 SPP1 抗体) by deficient TSC1 (显示 TSC1 抗体)/TSC2 (显示 TSC2 抗体) complex contributed to inactivation of AKT in TSC (显示 SLC12A3 抗体) cells

  2. Our results suggest that increasing Akt/ NF-kappaB (显示 NFKB1 抗体) is a crucial mediator of skin aging, which can increase the susceptibility of cell transformation.

  3. findings highlight a pivotal link between an epigenetic regulator, WHSC1, and key intracellular signaling molecules, AKT, RICTOR, and Rac1, to drive prostate cancer metastasis.

  4. Studies indicate that the Pten (显示 PTEN 抗体)+/- genotype displayed neoplasia in multiple organs, including the endometrium and that the Pten (显示 PTEN 抗体) is a key regulatory player in the PI3K/PTEN (显示 PTEN 抗体)/AKT pathway.

  5. a simple, linear, four-compartment ordinary differential equation (ODE) model of Akt activation that tracks both the biochemical state and the physical location of Akt, is reported.

  6. Psgl-1 (显示 SELPLG 抗体) deficiency accelerates bleomycin-induced lung fibrosis and inflammation in mice through activating the PI3K/AKT axis.

  7. Data show that docetaxel, rapamycin and tanespimycin multi-drug loaded micelles targeted against HSP90 (显示 HSP90 抗体) and the PI3K/AKT/mTOR (显示 FRAP1 抗体) pathway in prostate cancer.

  8. Furthermore, Leishmania RNA virus 1-induced TLR-3 (显示 TLR3 抗体) activation promoted parasite persistence by enhancing macrophage survival through Akt activation in a manner partially dependent on miR (显示 MLXIP 抗体)-155.

  9. Collectively, these findings showed that SA suppressed mammary gland development of pubertal mice, which was coincident with the SA-inhibited HC11 (显示 CCL2 抗体) proliferation, and was associated with inhibition of PI3K/Akt signaling pathway through activation of GPR120 (显示 O3FAR1 抗体).

  10. Findings suggest that atorvastatin attenuates diabetes-associated renal injury by reducing reactive oxygen species (ROS (显示 ROS1 抗体)) generation, RhoA (显示 RHOA 抗体) activity and normalizing Akt/GSK3beta (显示 GSK3b 抗体) signaling pathways.

Human V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. High AKT1 expression is associated with melanoma.

  2. PTEN (显示 PTEN 抗体) rs701848 and AKT1 rs2494752 polymorphisms might be a candidate pharmacogenomic factor to assess the susceptibility of and response and prognosis prediction for interindividualized CE(A)F chemotherapy in breast cancer patients.

  3. Lysophosphatidylcholine activates the Akt pathway to upregulate extracellular matrix protein production in human aortic valve cells and may contribute to the mechanism of valvular sclerosis associated with the development and progression of aortic stenosis.

  4. Cross-talk between Akt1 and Src (显示 SRC 抗体) regulates endothelial-barrier function.

  5. We found statistically significant DNA hypomethylation of the promoter regions of DRD3 (显示 DRD3 抗体) (P = 0.032), DRD4 (显示 DRD4 抗体) (P = 0.05), MB-COMT (显示 COMT 抗体) (P = 0.009), and AKT1 (P = 0.0008) associated with increased expression of the corresponding genes in patients with methamphetamine psychosis (P = 0.022, P = 0.034, P = 0.035, P = 0.038, respectively)

  6. High AKT1 expression is associated with T-cell leukemia.

  7. Results indicate that p110alpha (显示 PIK3CA 抗体) primarily mediates PI3K (显示 PIK3CA 抗体)/AKT signaling in HER2 (显示 ERBB2 抗体)+ PTEN (显示 PTEN 抗体) deficient breast tumors whereas p110beta conditionally mediates HER2 (显示 ERBB2 抗体)/PI3K (显示 PIK3CA 抗体) signaling in the absence of p110alpha (显示 PIK3CA 抗体).

  8. AKT1 mutation is associated with olfactory groove meningiomas.

  9. Activation of stromal MYC (显示 MYC 抗体) was critical for this reprogramming and for the sustained cellular responses elicited by LO, both in vitro and in vivo in an AKT1-dependent manner. Inhibition of LO internalization prevented activation of MYC (显示 MYC 抗体) and impaired the tumor-supporting properties of fibroblasts.

  10. Cytokines IL-2 (显示 IL2 抗体)/7/9 stimulation activates PI3K (显示 PIK3CA 抗体)/Akt pathways downstream of Ras in RasGRP1 (显示 RASGRP1 抗体) T-cell acute lymphoblastic leukemia (T-ALL).

Pig (Porcine) V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. These results indicate glycine enhances muscle protein mass under an inflammatory condition. The beneficial roles of glycine on the muscle are closely associated with maintaining Akt-mTOR (显示 FRAP1 抗体)-FOXO1 (显示 FOXO1 抗体) signaling and suppressing the activation of TLR4 (显示 TLR4 抗体) and/or NOD2 (显示 NOD2 抗体) signaling pathways.

  2. Data show that homocysteine (Hcy) can ameliorate the endothelium-independent hypoxic coronary vasoconstriction, in which the inhibition of PI3K/Akt signaling pathway may be involved.

  3. In pigs, lactose synthesis was significantly elevated with the increase of milk production and AKT1 could positively regulate lactose synthesis.

  4. In conclusion, our observations reveal that PRRSV triggers the activation of FAK-PI3K-AKT-Rac1 signaling pathway to facilitate its entry into cells.

  5. Host PI3K and Akt1 play a role in viral gene expression, leading to an increase in porcine reproductive and respiratory syndrome virus replication.

  6. Activity of AKT is not essential for induction of germinal vesicle breakdown in porcine oocytes but plays a substantial role during progression of meiosis to MI/MII-stage.

  7. IL-4 induced activation of Akt/SREBP-1/lipid biosynthesis in EC, resulting in protection against membrane attack complex and melittin, in association with mitochondrial protection.

  8. findings show that megalin (显示 LRP2 抗体) is the sensor that determines whether cells will be protected or injured by albumin (显示 ALB 抗体); it binds protein kinase B (PKB) in a D-3-phosphorylated phospholipid-insensitive manner, anchoring PKB in the luminal plasma membrane [

  9. protein kinase B (PKB/Akt)was localized in the granulosa cells of primordial follicles and in the basal layers of the granulosa cells of preantral and antral follicles, but were not localized in atretic follicles and corpora lutea

  10. Akt signaling in porcine patellofemoral joint cartilage is dependent upon frequency of loading, cartilage zone, and the time interval between loading and cartilage harvest.

Cow (Bovine) V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. These results demonstrate that activation of AKT is required for gonadotropin regulation of CTNNB1 (显示 CTNNB1 抗体) accumulation and subsequent ovarian E2 production.

  2. Caveolin-1 (显示 CAV1 抗体) scaffolding domain residue phenylalanine 92 modulates Akt signaling

  3. TG2 (显示 TGM2 抗体) contributes to 5-hydroxytryptamine-induced distal pulmonary artery smooth muscle cell proliferation via promotion of AKT signaling, likely via its serotonylation.

  4. results suggest that PI3K-Akt activity is important for the internalization of S. aureus and phosphorylation of GSK-3alpha, GSK-3beta (显示 GSK3b 抗体), and NF-kappaB (显示 NFKB1 抗体).

  5. The current study was designed to determine mechanisms underlying 20-hydroxyeicosatetraenoic acid -stimulated nitric oxide (NO) release, and particularly the role of NADPH oxidase (显示 NOX1 抗体), reactive oxygen species, and PI3-kinase (显示 PIK3CA 抗体) in stimulated NO release.

  6. PI3K/Akt and p53 (显示 TP53 抗体) are redox-regulated in bovine aortic endothelial cells exposed to hydrogen peroxide

  7. Thus our data demonstrate that hypoxia-induced adventitial fibroblast proliferation requires activation and interaction of PI3K, Akt, mTOR (显示 FRAP1 抗体), p70S6K (显示 RPS6KB1 抗体), and ERK1/2 (显示 MAPK1/3 抗体).

  8. Gab1 (显示 GAB1 抗体) tyrosine phosphorylation is stimulated by flow shear stress to mediate protein kinase B and endothelial nitric-oxide synthase (显示 NOS3 抗体) activation in endothelial cells

  9. Losartan metabolite stimulates eNOS (显示 NOS3 抗体) phosphorylation and suppresses tumor necrosis factor alpha (显示 TNF 抗体)-induced endothelial cell apoptosis by activating AKT1.

  10. prostaglandin F2alpha phosphorylates TSC2 (显示 TSC2 抗体) and activates mTOR (显示 FRAP1 抗体) and ribosomal protein S6 (显示 RPS6 抗体) kinase (显示 RPS6KB1 抗体) signaling in an AKT-independent manner

AKT (AKT1) 抗原简介

Antigen Summary

The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene.

Alternative names and synonyms associated with AKT (AKT1)

  • v-akt murine thymoma viral oncogene homolog 1 (AKT1) 抗体
  • v-akt murine thymoma viral oncogene homolog 1 (akt1) 抗体
  • CG4006 gene product from transcript CG4006-RA (Akt1) 抗体
  • potassium channel AKT1 (KT1) 抗体
  • thymoma viral proto-oncogene 1 (Akt1) 抗体
  • v-akt murine thymoma viral oncogene homolog 1 (Akt1) 抗体
  • akt 抗体
  • akt-1 抗体
  • Akt/PKB 抗体
  • akt1 抗体
  • ATAKT1 抗体
  • CG4006 抗体
  • CWS6 抗体
  • D-Akt 抗体
  • dakt 抗体
  • dAKT/dPKB 抗体
  • dAkt/PKB 抗体
  • dakt1 抗体
  • DAKT1/PKB 抗体
  • Dmel\\CG4006 抗体
  • dPKB 抗体
  • DRAC-PK 抗体
  • DRAC-PK66 抗体
  • DRAC-PK85 抗体
  • F18A8.2 抗体
  • F18A8_2 抗体
  • K+ transporter 1 抗体
  • l(3)04226 抗体
  • l(3)89Bq 抗体
  • p-Akt 抗体
  • pAkt 抗体
  • PKB 抗体
  • PKB-ALPHA 抗体
  • PKB/Akt 抗体
  • PKB/dAKT 抗体
  • PKBalpha 抗体
  • PRKBA 抗体
  • Rac 抗体
  • RAC-ALPHA 抗体
  • RacPK 抗体
  • v-akt 抗体
  • v-akt1 抗体
  • xAct 抗体

Protein level used designations for AKT1

RAC-alpha serine/threonine-protein kinase , protein kinase B , v-akt murine thymoma viral oncogene homolog 1 , Akt kinase , Akt1-PA , Akt1-PB , Akt1-PC , CG4006-PA , CG4006-PB , CG4006-PC , dAkt kinase , related to PKA to PKC protein kinases , related to the A and C kinases , AKT1 kinase , PKB alpha , RAC-PK-alpha , protein kinase B alpha , protein kinase B-alpha , proto-oncogene c-AKT , related to A and C kinases , proto-oncogene c-Akt , rac protein kinase alpha , RAC protein kinase alpha RAC-PK alpha , murine thymoma viral (v-akt) oncogene homolog 1 , thymoma viral proto-oncogene 1 , Akt , protein kinase Akt-1 , protein kinase B, alpha , xAkt , serine/threonine protein kinase , v-akt murine thymoma viral oncogene-like 1 , v-akt murine thymoma viral oncogene-like protein 1

100294652 Ovis aries
697747 Macaca mulatta
740898 Pan troglodytes
100101714 Xenopus (Silurana) tropicalis
100490038 Xenopus (Silurana) tropicalis
41957 Drosophila melanogaster
100556289 Anolis carolinensis
100587109 Nomascus leucogenys
817206 Arabidopsis thaliana
11651 Mus musculus
207 Homo sapiens
24185 Rattus norvegicus
399170 Xenopus laevis
395928 Gallus gallus
490878 Canis lupus familiaris
100126861 Sus scrofa
280991 Bos taurus
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