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anti-AKT (AKT1) 抗体产品概述

Full name:
anti-V-Akt Murine Thymoma Viral Oncogene Homolog 1 抗体 (AKT1)
在www.antibodies-online.cn可供1242 V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) 抗体的43不同的供货商。 再加上,我们可以发AKT 试剂盒 (50)AKT 蛋白 (40)和数多这个蛋白质的别的产品。 总共1431 AKT产品已列进来了。
别名:
akt, akt-1, Akt/PKB, akt1, ATAKT1, CG4006, CWS6, D-Akt, dakt, dAKT/dPKB, dAkt/PKB, dakt1, DAKT1/PKB, Dmel\\CG4006, dPKB, DRAC-PK, DRAC-PK66, DRAC-PK85, F18A8.2, F18A8_2, K+ transporter 1, l(3)04226, l(3)89Bq, p-Akt, pAkt, PKB, PKB-ALPHA, PKB/Akt, PKB/dAKT, PKBalpha, POTASSIUM TRANSPORTER, PRKBA, Rac, RAC-ALPHA, RacPK, v-akt, v-akt1, xAct

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引用最多的anti-AKT 抗体

  1. Human Polyclonal AKT Primary Antibody for DB - ABIN389509 : DeBusk, Hallahan, Lin: Akt is a major angiogenic mediator downstream of the Ang1/Tie2 signaling pathway. in Experimental cell research 2004 (PubMed)
    Show all 4 references for ABIN389509

  2. Chimpanzee Monoclonal AKT Primary Antibody for EIA, IF - ABIN400784 : Jones, Jakubowicz, Pitossi, Maurer, Hemmings: Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily. in Proceedings of the National Academy of Sciences of the United States of America 1991 (PubMed)
    Show all 4 references for ABIN400784

  3. Human Polyclonal AKT Primary Antibody for FACS, WB - ABIN652283 : Liao, Grobholz, Abel, Trojan, Michel, Angel, Mayer: Increase of AKT/PKB expression correlates with gleason pattern in human prostate cancer. in International journal of cancer. Journal international du cancer 2003 (PubMed)
    Show all 4 references for ABIN652283

  4. Human Monoclonal AKT Primary Antibody for EIA, IF - ABIN400786 : Staal: Molecular cloning of the akt oncogene and its human homologues AKT1 and AKT2: amplification of AKT1 in a primary human gastric adenocarcinoma. in Proceedings of the National Academy of Sciences of the United States of America 1987 (PubMed)
    Show all 4 references for ABIN400786

  5. Human Polyclonal AKT Primary Antibody for WB - ABIN389510 : Bourguignon, Singleton, Diedrich et al.: Hyaluronan-CD44 interaction with Rac1-dependent protein kinase N-gamma promotes phospholipase Cgamma1 activation, Ca(2+) signaling, and cortactin-cytoskeleton function leading to keratinocyte ... in The Journal of biological chemistry 2004 (PubMed)
    Show all 3 references for ABIN389510

  6. Chicken Polyclonal AKT Primary Antibody for EIA, IHC (fro) - ABIN117897 : Lawlor, Alessi: PKB/Akt: a key mediator of cell proliferation, survival and insulin responses? in Journal of cell science 2001 (PubMed)
    Show all 2 references for ABIN117897

  7. Human Polyclonal AKT Primary Antibody for IF (p), IHC (p) - ABIN725195 : Xu, Huang, Xie, Lin, Guo, Zhuang, Lin, Zhou, Li, Huang, Wei, Man, Zhang: The expression of cytoglobin as a prognostic factor in gliomas: a retrospective analysis of 88 patients. in BMC cancer 2013 (PubMed)
    Show all 2 references for ABIN725195

  8. Human Polyclonal AKT Primary Antibody for FACS, IHC (p) - ABIN654500 : Chen, Gomes, Monteiro, Wong, Wu, Ng, Karadedou, Millour, Ip, Cheung, Sunters, Chan, Lam, Khoo: Constitutively nuclear FOXO3a localization predicts poor survival and promotes Akt phosphorylation in breast cancer. in PLoS ONE 2010 (PubMed)

更多抗AKT的相互作用对抗体

Fruit Fly (Drosophila melanogaster) V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. subtle manipulation of foxo (显示 FOXO 抗体) through Akt1 can enhance survival during adverse nutrient conditions in Drosophila.

  2. The developmental delay of these novel Akt1 hypomorphs results in a latent phenotype uncovered by generation of somatic clones

  3. these data show that Drosophila Trbl has a conserved role to bind Akt and block Akt-mediated insulin signaling, and implicate Trib proteins as novel sites of signaling pathway integration that link nutrient availability with cell growth and proliferation

  4. AKT1 and caspase-dependent regulation of Acn stability adjusts basal autophagy levels.

  5. Akt1 governs two critical elements of synapse development, neurotransmitter receptor (显示 GRIN1 抗体) localization, and postsynaptic membrane elaboration

  6. Tsc2 (显示 TSC2 抗体) mutants showed a dramatic decrease in the levels of phosphorylated Akt, and interestingly, Akt mutants phenocopied Tsc2 (显示 TSC2 抗体) mutants, leading to the hypothesis that Tsc2 (显示 TSC2 抗体) and Akt might work via the same genetic pathway to regulate synapse growth.

  7. Hippo signaling not only blocks cell division and promotes apoptosis, but also regulates cellular growth by inhibiting the Akt pathway activity.

  8. Regeneration of Drosophila sensory neuron axons and dendrites is regulated by the Akt pathway involving Pten (显示 PTEN 抗体) and microRNA bantam.

  9. Overexpression of Akt enhanced Sindbis virus replication.

  10. Perturbation of the Akt/Gsk3-beta (显示 GSK3b 抗体) signalling pathway is common to Drosophila expressing expanded untranslated CAG, CUG and AUUCU repeat RNAs.

Arabidopsis thaliana V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. results suggest that NO decreases K(+) absorption by promoting the synthesis of vitamin B6 PLP (显示 FNTA 抗体), which further represses the activity of K(+) channel (显示 KCNC4 抗体) AKT1 in Arabidopsis.

  2. Examination of the athak5 atakt1 double mutant, revealing novel aspects of an uptake system as yet unidentified by genetic means.

  3. AKT1 is regulated by CIPK23 in guard cells and is involved in water stress responses.

  4. These findings provide further insights into the signaling network consisting of CBL (显示 CBL 抗体)-CIPK-PP2C interactions in the activation of the AKT1 channel.

  5. Electrophysiological results showed that AtKC1 inhibited the AKT1-mediated inward K(+) currents and negatively shifted the voltage dependence of AKT1 channels.

  6. AtHAK5 and AKT1 are vital for plant growth and development at low K+ concentrations.

  7. In the range between 0.01 and 0.05 mM K+ AtHAK5 and AtAKT1 are the only contributors to K+ acquisition. At higher K+ concentrations, unknown systems come into operation and participate together with AtAKT1 in low-affinity K+ uptake.

  8. CIPK23 directly phosphorylates the K+ transporter AKT1

  9. Data show that interacting calcium sensors (CBL1 and CBL9) together with CIPK23, but not either alone, activated the AKT1 channel in a Ca(2 (显示 CA2 抗体)+)-dependent manner, connecting the Ca(2 (显示 CA2 抗体)+) signal to K(+) uptake through activation of a K(+) channel (显示 KCNC4 抗体).

  10. AtAKT1 mediates K+ absorption at high concentrations, and remains active in the presence of NH4+ although activity is reduced.

Mouse (Murine) V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. BAY 1125976 is a potent and highly selective allosteric AKT1/2 inhibitor.

  2. These findings indicated that VPA's neuroprotective effect in the MPP(+)-model of Parkinson's disease is associated with GSK3beta (显示 GSK3b 抗体) phosphorylation via Akt and ERK (显示 EPHB2 抗体) activation in the mitochondrial intrinsic apoptotic pathway.

  3. PLIO treatment inhibited nuclear factorkappaB (NFkappaB) nuclear translocation in B16F10 cells. In addition, PLIO treatment inhibited the phosphorylation of c-Jun (显示 JUN 抗体) Nterminal kinases and AKT

  4. this study shows that Irbesartan can ameliorate hyperlipidemia and liver steatosis by upregulating Akt signaling pathway and inducing liver autophagy

  5. BDNF (显示 BDNF 抗体)-overexpression may not only facilitate the recovery of locomotor function via AKT pathway, but also contributed simultaneously to thermal hyperalgesia after spinal cord injury

  6. Data suggest that expression, processing, and activation of (that is, signal transduction via) Notch1 (neurogenic locus notch homolog protein 1 (显示 NOTCH1 抗体)), Pten (phosphatase and tensin homolog (显示 PTEN 抗体)), and Akt1 (thymoma viral proto-oncogene 1) are involved in oogenesis; oogenesis proceeds via both recruitment of primordial follicles and proliferation of granulosa cells.

  7. this study shows that remote ischemic postconditioning protects against renal ischemia/reperfusion injury via activation of TOPK (显示 PBK 抗体)/PTEN (显示 PTEN 抗体)/Akt signaling pathway

  8. Results suggest a role of ST6GalNAc I (显示 ST6GALNAC1 抗体) in promoting the growth and invasion of hepatocarcinoma cells through regulating PI3K/AKT/NF-kappa B (显示 NFKB1 抗体) signaling, and ST6GalNAc I (显示 ST6GALNAC1 抗体) might be a marker for the prognosis and therapy of hepatocarcinoma.

  9. The data indicate that the balanced activities of two related serine/threonine kinases, AKT and SGK1 (显示 SGK1 抗体), critically govern the embryo implantation process.

  10. These results suggest that DDI may improve insulin (显示 INS 抗体) sensitivity through the activation of Akt signaling, which leads to enhanced glucose uptake.

Human V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. NEDD4L (显示 NEDD4L 抗体) negatively regulates PIK3CA (显示 PIK3CA 抗体) protein levels via ubiquitination and is required for the maintenance of PI3K (显示 PIK3CA 抗体)-AKT signaling pathway.

  2. Collectively, these findings demonstrate that stimulation of G12 (显示 TCF3 抗体) proteins is capable of promoting invasion through RhoA (显示 RHOA 抗体)/ROCK-JNK (显示 MAPK8 抗体) activation.

  3. These results demonstrate that NLRC5 (显示 NLRC5 抗体) promotes hepatocellular carcinoma progression via the AKT/VEGF-A (显示 VEGFA 抗体) signaling pathway

  4. This study investigated the associations between three polymorphisms (rs1130214, rs3730358, and rs2494732) in AKT1 and the risk of development of prostate cancer. Compared to the CC genotype of the rs3730358 polymorphism, the CT genotype of the same polymorphism was strongly associated with a decreased risk of prostate cancer. The genotype CT of rs3730358 of AKT1 was associated with a decreased risk of prostate cancer.

  5. after AKT-mediated phosphorylation at serine 319, FOXO1 binds to IQGAP1, a hub for activation of the MAPK pathway, and impedes IQGAP1-dependent phosphorylation of ERK1/2 (pERK1/2).

  6. Upregulation of AKT1 is associated with thyroid cancer.

  7. The overexpression of CSN6 (显示 COPS6 抗体) reduced the effect of quercetin treatment on HT29 cells, suggesting that quercetininduced apoptosis may involve the AktCSN6Myc signaling axis in HT29 cells.

  8. In conclusion, overexpression of CXCL8 (显示 IL8 抗体) induced cell proliferation, migration and invasion of colon cancer LoVo cells. CXCL8 (显示 IL8 抗体) may act through induction of EMT (显示 ITK 抗体) via the PI3K (显示 PIK3CA 抗体)/AKT/NF-kappaB (显示 NFKB1 抗体) signaling axis

  9. Transcriptomic dysregulations might be mediated by a limited set of transcription factors perturbed by AKT1 hyperactivation in JGCTs

  10. In-frame duplications in the pleckstrin (显示 PLEK 抗体)-homology domain (PHD (显示 PDC 抗体)) found in more than 60% of Juvenile Granulosa Cell Tumors (JGCTs)

Pig (Porcine) V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. In pigs, lactose synthesis was significantly elevated with the increase of milk production and AKT1 could positively regulate lactose synthesis.

  2. In conclusion, our observations reveal that PRRSV triggers the activation of FAK-PI3K-AKT-Rac1 signaling pathway to facilitate its entry into cells.

  3. Host PI3K and Akt1 play a role in viral gene expression, leading to an increase in porcine reproductive and respiratory syndrome virus replication.

  4. Activity of AKT is not essential for induction of germinal vesicle breakdown in porcine oocytes but plays a substantial role during progression of meiosis to MI/MII-stage.

  5. IL-4 induced activation of Akt/SREBP-1/lipid biosynthesis in EC, resulting in protection against membrane attack complex and melittin, in association with mitochondrial protection.

  6. findings show that megalin (显示 LRP2 抗体) is the sensor that determines whether cells will be protected or injured by albumin (显示 ALB 抗体); it binds protein kinase B (PKB) in a D-3-phosphorylated phospholipid-insensitive manner, anchoring PKB in the luminal plasma membrane [

  7. protein kinase B (PKB/Akt)was localized in the granulosa cells of primordial follicles and in the basal layers of the granulosa cells of preantral and antral follicles, but were not localized in atretic follicles and corpora lutea

  8. Akt signaling in porcine patellofemoral joint cartilage is dependent upon frequency of loading, cartilage zone, and the time interval between loading and cartilage harvest.

  9. in VSMCs exposed to hyperglycemia, IGF-I (显示 IGF1 抗体) stimulation of Shc (显示 SHC1 抗体) facilitates the transfer of Grb2 (显示 GRB2 抗体) to p85 (显示 ARHGEF7 抗体) resulting in enhanced PI3K activation and AKT phosphorylation leading to enhanced cell proliferation and migration

  10. There was no correlation of infarct size with expression or phosphorylation of AKT in ischemic postconditioning.

Cow (Bovine) V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) interaction partners

  1. These results demonstrate that activation of AKT is required for gonadotropin regulation of CTNNB1 (显示 CTNNB1 抗体) accumulation and subsequent ovarian E2 production.

  2. Caveolin-1 (显示 CAV1 抗体) scaffolding domain residue phenylalanine 92 modulates Akt signaling

  3. TG2 (显示 TGM2 抗体) contributes to 5-hydroxytryptamine-induced distal pulmonary artery smooth muscle cell proliferation via promotion of AKT signaling, likely via its serotonylation.

  4. results suggest that PI3K-Akt activity is important for the internalization of S. aureus and phosphorylation of GSK-3alpha, GSK-3beta (显示 GSK3b 抗体), and NF-kappaB (显示 NFKB1 抗体).

  5. The current study was designed to determine mechanisms underlying 20-hydroxyeicosatetraenoic acid -stimulated nitric oxide (NO) release, and particularly the role of NADPH oxidase (显示 NOX1 抗体), reactive oxygen species, and PI3-kinase (显示 PIK3CA 抗体) in stimulated NO release.

  6. PI3K/Akt and p53 (显示 TP53 抗体) are redox-regulated in bovine aortic endothelial cells exposed to hydrogen peroxide

  7. Thus our data demonstrate that hypoxia-induced adventitial fibroblast proliferation requires activation and interaction of PI3K, Akt, mTOR (显示 FRAP1 抗体), p70S6K (显示 RPS6KB1 抗体), and ERK1/2 (显示 MAPK1/3 抗体).

  8. Gab1 (显示 GAB1 抗体) tyrosine phosphorylation is stimulated by flow shear stress to mediate protein kinase B and endothelial nitric-oxide synthase (显示 NOS3 抗体) activation in endothelial cells

  9. Losartan metabolite stimulates eNOS (显示 NOS3 抗体) phosphorylation and suppresses tumor necrosis factor alpha (显示 TNF 抗体)-induced endothelial cell apoptosis by activating AKT1.

  10. prostaglandin F2alpha phosphorylates TSC2 (显示 TSC2 抗体) and activates mTOR (显示 FRAP1 抗体) and ribosomal protein S6 (显示 RPS6 抗体) kinase (显示 RPS6KB1 抗体) signaling in an AKT-independent manner

AKT (AKT1) 抗原简介

Antigen Summary

The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene.

Alternative names and synonyms associated with AKT (AKT1)

  • v-akt murine thymoma viral oncogene homolog 1 (AKT1) 抗体
  • v-akt murine thymoma viral oncogene homolog 1 (akt1) 抗体
  • CG4006 gene product from transcript CG4006-RA (Akt1) 抗体
  • potassium channel AKT1 (KT1) 抗体
  • thymoma viral proto-oncogene 1 (Akt1) 抗体
  • v-akt murine thymoma viral oncogene homolog 1 (Akt1) 抗体
  • akt 抗体
  • akt-1 抗体
  • Akt/PKB 抗体
  • akt1 抗体
  • ATAKT1 抗体
  • CG4006 抗体
  • CWS6 抗体
  • D-Akt 抗体
  • dakt 抗体
  • dAKT/dPKB 抗体
  • dAkt/PKB 抗体
  • dakt1 抗体
  • DAKT1/PKB 抗体
  • Dmel\\CG4006 抗体
  • dPKB 抗体
  • DRAC-PK 抗体
  • DRAC-PK66 抗体
  • DRAC-PK85 抗体
  • F18A8.2 抗体
  • F18A8_2 抗体
  • K+ transporter 1 抗体
  • l(3)04226 抗体
  • l(3)89Bq 抗体
  • p-Akt 抗体
  • pAkt 抗体
  • PKB 抗体
  • PKB-ALPHA 抗体
  • PKB/Akt 抗体
  • PKB/dAKT 抗体
  • PKBalpha 抗体
  • POTASSIUM TRANSPORTER 抗体
  • PRKBA 抗体
  • Rac 抗体
  • RAC-ALPHA 抗体
  • RacPK 抗体
  • v-akt 抗体
  • v-akt1 抗体
  • xAct 抗体

Protein level used designations for AKT1

RAC-alpha serine/threonine-protein kinase , protein kinase B , v-akt murine thymoma viral oncogene homolog 1 , Akt kinase , Akt1-PA , Akt1-PB , Akt1-PC , CG4006-PA , CG4006-PB , CG4006-PC , dAkt kinase , related to PKA to PKC protein kinases , related to the A and C kinases , AKT1 kinase , PKB alpha , RAC-PK-alpha , protein kinase B alpha , protein kinase B-alpha , proto-oncogene c-AKT , related to A and C kinases , proto-oncogene c-Akt , rac protein kinase alpha , RAC protein kinase alpha RAC-PK alpha , murine thymoma viral (v-akt) oncogene homolog 1 , thymoma viral proto-oncogene 1 , Akt , protein kinase Akt-1 , protein kinase B, alpha , xAkt , serine/threonine protein kinase , v-akt murine thymoma viral oncogene-like 1 , v-akt murine thymoma viral oncogene-like protein 1

GENE ID SPECIES
100294652 Ovis aries
697747 Macaca mulatta
740898 Pan troglodytes
100101714 Xenopus (Silurana) tropicalis
100490038 Xenopus (Silurana) tropicalis
41957 Drosophila melanogaster
100556289 Anolis carolinensis
100587109 Nomascus leucogenys
817206 Arabidopsis thaliana
11651 Mus musculus
207 Homo sapiens
24185 Rattus norvegicus
399170 Xenopus laevis
395928 Gallus gallus
490878 Canis lupus familiaris
100126861 Sus scrofa
280991 Bos taurus
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