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CD8 FITC - CD28 PE Bi-Test Reagent

ABIN2763769 产品详细信息, 供应商: Log in to see
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适用

宿主
小鼠
标记
FITC,PE
应用范围
Flow Cytometry (FACS)
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品牌 Bi-Test™
亚型 IgG1
纯化方法 Protein A/G Chromatography
背景 Identification of human cytotoxic/suppressor T cells expressing the 32 and 43,000 M.W. surface antigen. CD38 antigen is an integral membrane glycoprotein, M.W. 45 kD. Anti-human CD28 binds the 44 kDa MW cell surface protein on the surface of most T cells. CD28 acts as the ligand for the B7/BB-1 Molecule on the surface of activated B cells. B7/BB-1 co-stimulates T cells through CD28, along with CD2 and CD3. CD28 antigen is a disulfide-linked homodimeric glycoprotein. The CD28 antigen is present on approximately 60 % -80 % T lymphocytes (95 % of CD4 and 50 % of CD8 lymphocytes). CD28 regulates the expression of cytokines by T cells, not only IL-2, but also IL-1 alpha and CSF-1, usually synthesized by accessory cells. CD28 functions as a cell adhesion molecule (CAM) for certain T cell subsets.
限制 仅限研究用
储存条件 4 °C