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These results elucidate a novel role of Bex1 (显示 BEX2 抗体) in myogenesis through regulating myoblast fusion.
Bex (显示 NGFRAP1 抗体) family members play important roles in the formation of protein network hubs.
Bex1 (显示 BEX2 抗体) protein is over-expressed as a result of peripheral axonal damage and antagonizes the axon outgrowth inhibitory effect of myelin-associated glycoprotein (显示 MAG 抗体).
Trophectoderm-specific expression of the X-linked Bex1/Rex3 gene in preimplantation stage mouse embryos.
In situ hybridization demonstrates cellular co-localization of olfactory marker protein mRNA with mRNAs for Bex1, Bex2, and Bex3 in olfactory receptor neuronss in olfactory tissue of the mouse
Bex3 (显示 NGFRAP1 抗体) may be required in target tissues for mitochondrial function at a distinct phase of the cellular growth cycle.
Thus, our results provide the first evidence that Bex1 (显示 BEX2 抗体)-KO mice show altered muscle regeneration, and allow us to propose that the interaction of Bex1 (显示 BEX2 抗体) with Ca(2 (显示 CA2 抗体)+)/CaM may be involved in skeletal muscle regeneration.
Bex1 (显示 BEX2 抗体) and 2 have been characterized as interacting partners of the olfactory marker protein (OMP (显示 OMP 抗体)). Bex (显示 NGFRAP1 抗体) immunoreactivity (ir) was primarily localized to neuronal cells within several regions of the brain.
loss of BEX1 expression in FLT3 (显示 FLT3 抗体)-ITD driven AML (显示 RUNX1 抗体) potentiates oncogenic signaling and leads to decreased overall survival
Our results revealed an interaction between BEX1 and BCL-2 (显示 BCL2 抗体) and a novel mechanism of imatinib resistance mediated by the BEX1/BCL-2 (显示 BCL2 抗体) pathway.
Epigenetic inactivation of BEX1 supports its role as a candidate tumour suppressor gene in intracranial ependymoma
Silencing of BEX1 and LDOC1 (显示 LDOC1 抗体) by promoter hypermethylation might represent a critical event in the molecular pathogenesis of oral squamous cell carcinoma (OSCC) and the male predominance of OSCC occurrence.
This new human gene is mapped to the X chromosome and has an expression pattern of a spermatogenesis-related (显示 SYCE2 抗体) gene.
Two novel brain expressed genes, BEX1 and BEX2 are identified; they are silenced in all glioma specimens and exhibit extensive promoter hypermethylation.
Regulator of mitochondrial apoptosis and G1 cell cycle. Regulates the level of PP2A regulatory subunit B and PP2A phosphatase activity (By similarity).
brain expressed, X-linked 1
, brain-expressed X-linked protein 1 homolog
, protein BEX1
, reduced expression 3
, reduced expression protein 3
, brain-expressed X-linked protein 2 homolog
, protein BEX2
, brain-expressed X-linked protein 1
, ovarian granulosa cell 13.0 kDa protein hGR74
, brain expressed gene 1