anti-LPAR1 (LPAR1) 抗体产品概述

Full name:
anti-Lysophosphatidic Acid Receptor 1 抗体 (LPAR1)
在www.antibodies-online.cn可供56 Lysophosphatidic Acid Receptor 1 (LPAR1) 抗体的14不同的供货商。 再加上,我们可以发LPAR1 试剂盒 (13)LPAR1 蛋白 (4)和数多这个蛋白质的别的产品。 总共77 LPAR1产品已列进来了。
别名:
5031439C20, AI326300, EDG-2, edg2, Gpcr26, GPR26, Kdt2, lpA1, Mrec1.3, rec.1.3, si:dz22b13.1, si:dz46m7.1, vzg-1, VZG1, zgc:92157

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引用最多的anti-LPAR1 抗体

  1. Chicken Polyclonal LPAR1 Primary Antibody for ICC, IF - ABIN315888 : Park, Kazlauskas: Primary human endothelial cells secrete agents that reduce responsiveness to lysophosphatidic acid (LPA). in Bioscience reports 2012 (PubMed)
    Show all 3 references for 315888

  2. Human Polyclonal LPAR1 Primary Antibody for IHC (p) - ABIN270785 : Horak, Mendoza, Vega-Valle, Albaugh, Graff-Cherry, McDermott, Hua, Merino, Steinberg, Khanna, Steeg: Nm23-H1 suppresses metastasis by inhibiting expression of the lysophosphatidic acid receptor EDG2. in Cancer research 2007 (PubMed)
    Show all 2 references for 270785

  3. Human Polyclonal LPAR1 Primary Antibody for EIA, WB - ABIN358617 : Boucharaba, Serre, Guglielmi, Bordet, Clézardin, Peyruchaud: The type 1 lysophosphatidic acid receptor is a target for therapy in bone metastases. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)

更多抗LPAR1的相互作用对抗体

Human Lysophosphatidic Acid Receptor 1 (LPAR1) interaction partners

  1. LPA1 plays a critical role in EGF (显示 EGF 抗体) responses and that FFA4 agonists inhibit proliferation by suppressing positive cross-talk between LPA1 and the EGF receptor (显示 EGFR 抗体)

  2. ADAMTS7 and LPA single nucleotide polymorphisms are related to a 24-h ambulatory systolic-diastolic pressure regression index.

  3. Polymorphism rs7023923 located near LPAR1 gene: the association of rs7023923 with monocytosis was confirmed among healthy blood donors (p = 0.0156) but not among patients admitted for elective coronarography (p = 0.61).

  4. These results suggest that autotaxin-LPA-LPA receptor 1-AKT1 signaling axis is critical for maintaining Cancer stem cells(CSC) characteristics through an autocrine loop and provide a novel therapeutic target for ovarian CSCs

  5. LPA (显示 APOA 抗体)-type agonist, via Carbonyl-oxygen/Lys39 interaction facilitates the formation of a hypothetical N-terminal cap tightly packed over the LPA1 heptahelical bundle.

  6. Data show high expression levels of LPAR2 (显示 LPAR2 抗体) and LPAR1 in endometrial cancer tissue with positive correlations with FIGO stage suggesting them as potential biomarkers for endometrial cancer progression.

  7. Data suggest LPA (lysophosphatidic acid; acting via LPAR1) and endothelin activate Cdc42, concurrent with biphasic decrease in Rac1 activity, differential effects on RhoA; LPA/endothelin stim. leads to remodeling of invadosomes in melanoma cells.

  8. we show that LPAR1 is a novel susceptibility gene for human essential hypertension and that stress, such as shortage of sleep, increases the susceptibility of patients with risk allele to essential hypertension.

  9. Study presents three crystal structures of LPA1 in complex with antagonist tool compounds selected and designed through structural and stability analyses.

  10. Results indicate that lysophosphatidic acid-lysophosphatidic acid receptor 1 (LPA (显示 APOA 抗体)-LPA1) signaling contributes to the activation of rheumatoid arthritis fibroblast-like synoviocytes (FLSs).

Mouse (Murine) Lysophosphatidic Acid Receptor 1 (LPAR1) interaction partners

  1. Data (including data from studies conducted in cells from knockout mice) suggest that signaling via Lpar1, Cd14 (显示 CD14 抗体), and Scara1 (显示 MSR1 抗体) mediates uptake of oxidized LDL by macrophages leading to foam cell formation; lysophosphatidic acid (LPA) induces expression of Cd14 (显示 CD14 抗体) and Scara1 (显示 MSR1 抗体) in macrophages. (Lpar1 = LPA receptor 1; Cd14 (显示 CD14 抗体) = monocyte differentiation antigen CD14 (显示 CD14 抗体); Scara1 (显示 MSR1 抗体) = scavenger receptor class A type I)

  2. Our results suggest that LPA-enhanced foam cell formation is mediated by LPA1/3 -AKT (显示 AKT1 抗体) activation and subsequent SRBI (显示 SCARB1 抗体) expression.

  3. Lysophosphatidic acid-LPA1 signaling is critically required for septation during alveolarization.

  4. Data show that lysophosphatidic acid receptor 1 (LPA1)-green fluorescent proteins can be used to directly quantify the running-induced increase in precursor proliferation.

  5. Results suggest a relevant role for the Lysophosphatidic acid/Lysophosphatidic acid receptor 1 signaling system in alcoholism. In addition, the LPA1-null mice emerge as a new model for genetic vulnerability to excessive alcohol drinking

  6. Data show that lysophosphatidic acid (LPA) induces phosphorylation of trkA (显示 NTRK1 抗体) receptor (TrkA (显示 NTRK1 抗体)) through lysophosphatidic acid receptor 1 (LPA1) binding to TrkA (显示 NTRK1 抗体)

  7. LPA receptor has a role in bone loss in ovariectomized mice, but the favorable effect of its inhibition on bone remodeling is less general than hypothesized

  8. These findings suggest that tumor and stromal LPA receptors, in particular LPA1 and LPA5 (显示 LPAR5 抗体), play different roles in invasion and the seeding of metastasis

  9. LPA1 receptor is involved in emotional behaviors and in the anatomical integrity of the corticolimbic circuit, the deregulation of which may be a susceptibility factor for anxiety disorders.

  10. These results suggest that Ile325, Tyr85, and Leu87 within LPA1 are essential for LPA1 protein properly folding in the ER.

Cow (Bovine) Lysophosphatidic Acid Receptor 1 (LPAR1) interaction partners

  1. Lysophosphatidic acid stimulates PGE (显示 LIPF 抗体)(2) production, cell viability, and intracellular calcium ion mobilization in cultured stromal endometrial cells via Ki16425-sensitive LPA1 receptors.

Zebrafish Lysophosphatidic Acid Receptor 1 (LPAR1) interaction partners

  1. the ATX-LPA-LPAR axis is a critical regulator of embryonic vascular development that is conserved in vertebrates

  2. LPA(1) is necessary for lymphatic vessel formation during embryonic development in zebrafish.

LPAR1 抗原简介

Antigen Summary

The integral membrane protein encoded by this gene is a lysophosphatidic acid (LPA) receptor from a group known as EDG receptors. These receptors are members of the G protein-coupled receptor superfamily. Utilized by LPA for cell signaling, EDG receptors mediate diverse biologic functions, including proliferation, platelet aggregation, smooth muscle contraction, inhibition of neuroblastoma cell differentiation, chemotaxis, and tumor cell invasion. Two transcript variants encoding the same protein have been identified for this gene

Alternative names and synonyms associated with LPAR1

  • lysophosphatidic acid receptor 1 (LPAR1) 抗体
  • lysophosphatidic acid receptor 1 (LOC100355169) 抗体
  • lysophosphatidic acid receptor 1 (Lpar1) 抗体
  • lysophosphatidic acid receptor 1 (lpar1) 抗体
  • 5031439C20 抗体
  • AI326300 抗体
  • EDG-2 抗体
  • edg2 抗体
  • Gpcr26 抗体
  • GPR26 抗体
  • Kdt2 抗体
  • lpA1 抗体
  • Mrec1.3 抗体
  • rec.1.3 抗体
  • si:dz22b13.1 抗体
  • si:dz46m7.1 抗体
  • vzg-1 抗体
  • VZG1 抗体
  • zgc:92157 抗体

Protein level used designations for LPAR1

endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2 , lysophosphatidic acid receptor 1 , lysophosphatidic acid receptor 1-like , LPA receptor 1 , LPA-1 , lysophosphatidic acid receptor Edg-2 , ventricular zone gene 1 , G-protein coupled receptor 26 , clone 4.9 , endothelial differentiation lysophosphatidic acid G-protein-coupled receptor 2 , rec1.3 , lpa1 , zlpa1 , endothelium differentiation gene 2

GENE ID SPECIES
427339 Gallus gallus
464655 Pan troglodytes
474800 Canis lupus familiaris
100355169 Oryctolagus cuniculus
100414340 Callithrix jacchus
100016607 Monodelphis domestica
100458931 Pongo abelii
100589911 Nomascus leucogenys
1902 Homo sapiens
14745 Mus musculus
116744 Rattus norvegicus
281136 Bos taurus
368461 Danio rerio
443346 Ovis aries
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