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We found that quercetin reduces the promoter activity of apoB (显示 APOB ELISA试剂盒), driven by the enforced expression of C/EBPb.
Chromatin immunoprecipitation analysis revealed that C/EBPbeta2 binds to multiple sites at the 5' promoter/regulatory region, introns, and the 3' untranslated region of the IGF-II gene.
C/EBPbeta negatively regulates PR-B (显示 PGR ELISA试剂盒) expression in glioblastoma cells.
High CEBPB expression is associated with recurrence in Glioma.
Study results show the role of WT1 (显示 WT1 ELISA试剂盒) in regulating decidualization in human endometrial stromal cells. C/EBPbeta is an upstream gene that regulates WT1 (显示 WT1 ELISA试剂盒) expression by binding to the novel enhancer region.
EGFR (显示 EGFR ELISA试剂盒) and C/EBP-beta oncogenic signaling is bidirectional in human glioma and varies with the C/EBP-beta isoform
Studied expression of CD147 in both ALK (显示 ALK ELISA试剂盒)+ and ALK (显示 ALK ELISA试剂盒)- anaplastic large-cell lymphoma; found CD147 to be a downstream target for activation by C/EBPbeta.
Data show that in an in vitro acute lung injury model established by lipopolysaccharide induction, phosphorylation of C/EBP beta was decreased and bioinformatics analysis discovered a putative binding site of C/EBP beta in CCSP1 (显示 KIAA1199 ELISA试剂盒) promoter; LPS (显示 IRF6 ELISA试剂盒) stimulation reduced C/EBP beta phosphorylation and suppressed the transcription of CCSP1 (显示 KIAA1199 ELISA试剂盒).
Increased polyamine metabolism in CRC (显示 CALR ELISA试剂盒) could be driven by c-Myc (显示 MYC ELISA试剂盒) and C/EBPbeta rather than Bacteroides fragilis infection.
SBDS (显示 SBDS ELISA试剂盒) function is specifically required for efficient translation re-initiation into the protein isoforms C/EBPalpha (显示 CEBPA ELISA试剂盒)-p30 (显示 CENPV ELISA试剂盒) and C/EBPbeta-LIP, which is controlled by a single cis (显示 CISH ELISA试剂盒)-regulatory upstream open reading frame (uORF) in the 5' untranslated regions (5' UTRs) of both mRNAs.
A transcription factor complex consisting of ATF6 (显示 ATF6 ELISA试剂盒) (an endoplasmic reticulum-resident factor) and C/EBP-beta is required for the IFN-gamma-induced (显示 SAMHD1 ELISA试剂盒) expression of DAPK1 (显示 DAPK1 ELISA试剂盒) IFN-gamma-induced (显示 SAMHD1 ELISA试剂盒) proteolytic processing of ATF6 (显示 ATF6 ELISA试剂盒) and phosphorylation of C/EBP-beta are obligatory for the formation of this transcriptional complex
Data show that CCAAT/enhancer-binding protein beta (C/EBP beta) expression is increased in endothelial cells and retinal pigment epithelial cells infected by Toxoplasma gondii, resulting in the activation of autophagy in host cells by inhibiting mechanistic target of rapamycin (显示 FRAP1 ELISA试剂盒) protein (mTOR (显示 FRAP1 ELISA试剂盒)) pathway.
C/EBPbeta in hematopoietic cells is crucial to regulate diet-induced inflammation, hyperlipidemia and atherosclerosis development
C/EBPbeta or Stat3 (显示 STAT3 ELISA试剂盒) depletion by siRNA in sepsis Gr1 (显示 GSR ELISA试剂盒)(+)CD11b (显示 ITGAM ELISA试剂盒)(+) MDSCs inhibits miR (显示 MLXIP ELISA试剂盒)-21 and miR (显示 MLXIP ELISA试剂盒)-181b expression.
The present study indicates a requirement for C/EBPbeta in the insulin (显示 INS ELISA试剂盒)-mediated induction of SREBP-1c (显示 SREBF1 ELISA试剂盒) mRNA expression in rodent liver. Coupled with previous data showing that this induction requires LXRalpha (显示 NR1H3 ELISA试剂盒), our data reported herein indicate a requirement for both transcription factors.
elevated LIP/LAP ratio robustly increased Ogn (显示 OGN ELISA试剂盒) expression and cell death under stress by modulating the mitogen-activated protein kinase (显示 MAPK1 ELISA试剂盒)/activator protein 1 (显示 JUN ELISA试剂盒) pathway (MAPK (显示 MAPK1 ELISA试剂盒)/AP-1 (显示 JUN ELISA试剂盒)).
Ptn (显示 PTN ELISA试剂盒) may play a vital role in the progesterone-induced decidualization pathway via C/EBPB-cyclic AMP (显示 TMPRSS5 ELISA试剂盒)-Hand2 (显示 HAND2 ELISA试剂盒) signaling.
C/EBPbeta is a critical factor for Ly6C(-) monocyte survival, at least in part through upregulation of Csf1r (显示 CSF1R ELISA试剂盒).
these results support that decreasing C/EBPbeta expression prevents MDSC generation and decreases immunosuppression in septic mice, providing a target for sepsis treatment.
Functional characterization of C/EBPa (显示 CEBPA ELISA试剂盒) and C/EBPb proteomes suggests they can regulate novel pathways.
PARP-1 (显示 PARP1 ELISA试剂盒) attenuates adipogenesis by PARylating C/EBPb, a pro-adipogenic transcription factor, on three residues in its regulatory domain.
Results show that C/EBPbeta and C/EBPdelta (显示 CEBPD ELISA试剂盒) actively regulate the promotor region of both splicing variants Ppargamma1sv and Ppargamma2 (显示 PPARG ELISA试剂盒) in mouse adipocytes.
C/EBP-beta plays a vital role in regulating GPR120 (显示 O3FAR1 ELISA试剂盒) transcription.
The expression of porcine Prdx6 (显示 PRDX6 ELISA试剂盒) gene is up-regulated by C/EBPbeta and CREB (显示 CREB1 ELISA试剂盒).
Results show that expression changes of IGF1 (显示 IGF1 ELISA试剂盒) genes were associated with C/EBP (显示 CEBPA ELISA试剂盒) b expression during embryonic and postnatal development in porcine liver.
FoxO1 (显示 FOXO1 ELISA试剂盒) and C/EBPb regulate preadipocyte adipogenesis possibly through C/EBPb-> FoxO1 (显示 FOXO1 ELISA试剂盒)-> C/EBPb feedback regulatory loop and FoxO1 (显示 FOXO1 ELISA试剂盒)-C/EBPb protein complex.
the pig GPD1 (显示 GPD1 ELISA试剂盒) gene is regulated negatively by C/EBP beta in cultured kidney cells
GATA-4 (显示 GATA4 ELISA试剂盒) and C/EBPbeta are both required for FSH (显示 BRD2 ELISA试剂盒) +/- IGF-I (显示 IGF1 ELISA试剂盒) stimulation of the porcine steroidogenic acute regulatory protein (显示 STAR ELISA试剂盒) gene promoter in homologous granulosa cell cultures.
The differential expression of specific CEBPA (显示 CEBPA ELISA试剂盒)/B isoforms observed in maturing follicles and CL may contribute to changes in follicular cell differentiation and increasing steroidogenic capacity.
SREBP1a activated while C/EBP (显示 CEBPA ELISA试剂盒) factors downregulated the activity of the SCD1 (显示 SCD ELISA试剂盒) promoter.
These results indicate that the C/EBPbeta gene plays an important regulatory role in regulation of the cell cycle regulators and spermatogenesis-related (显示 SYCE2 ELISA试剂盒) genes expression and function of bovine SCs (显示 TWIST1 ELISA试剂盒).
Suppression of CPT1B (显示 CPT1B ELISA试剂盒) and induction of SCD (显示 SCD ELISA试剂盒) and CEBPB by supplemental arginine promotes increased adiposity in Angus steers.
Co-culture of adipocytes and myoblasts elicited an increase in C/EBPbeta and PPAR-gamma (显示 PPARG ELISA试剂盒) gene expression in differentiated myoblasts and an increase in GPR43 (显示 FFAR2 ELISA试剂盒) gene expression in adipocytes.
Interaction of C/EBP-beta and NF-Y factors constrains activity levels of the nutritionally controlled promoter IA expressing the acetyl-CoA carboxylase-alpha (显示 ACACA ELISA试剂盒) gene in cattle.
The role of NF-kappaB (显示 NFKB1 ELISA试剂盒) and C/EBP (显示 CEBPA ELISA试剂盒) factors in regulating basal and pathogen-induced expression of both genes from cattle, is investigated.
The 3' terminal end of the first intron of porcine SPP1 (显示 SPP1 ELISA试剂盒) harbors a C/EBPbeta binding site and this binding site is negatively affected by the mutant G allele.
2-chloroethyl ethyl sulfide exposure caused a 2.3-fold increase in the activation of C/EBP (显示 CEBPA ELISA试剂盒) accompanied with a 45% and 121% increase in the protein level of C/EBP beta and ICAM-1 (显示 ICAM1 ELISA试剂盒), respectively, and this effect was counteracted by the antioxidant liposome.
The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.
CCAAT/enhancer binding protein (C/EBP), beta
, CCAAT/enhancer-binding beta protein b
, CCAAT/enhancer-binding protein beta
, CCAAT/enhancer binding protein beta
, interleukin 6-dependent DNA-binding protein
, liver-enriched transcriptional activator protein
, nuclear factor NF-IL6
, nuclear factor of interleukin 6
, transcription factor 5
, C/EBP BETA
, interleukin-6-dependent-binding protein
, liver-enriched transcriptional activator
, nuclear protein Il6
, C/EBP beta
, c/EBP-related protein 2
, liver activating protein (LAP)
, nuclear factor-IL6
, silencer factor B
, c/EBP beta
, CCAAT box/enhancer binding protein beta
, CCR protein
, transcription factor NF-M