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Mouse (Murine) HHIP ELISA Kit for Sandwich ELISA - ABIN649191
Yan, Lv, Yang, Yao, Cui, Guo: Glioma stem cells enhance endothelial cell migration and proliferation via the Hedgehog pathway. in Oncology letters 2013
Hhip regulates muscle development both by sequestering Hedgehog and by modulating localization of Smoothened
Localized expression of Xhip may counteract certain overlapping signaling activities, which inhibit the induction of olfactory and lens placodes.
loss of AT2 R (显示 AGTR2 ELISA试剂盒) is associated with podocyte loss/dysfunction and is mediated, at least in part, via augmented ectopic hedgehog interacting protein expression in podocytes
this study shows that HHIP confers a risk for airway obstruction in general that is not driven exclusively by cigarette smoking, which is the main risk factor for chronic obstructive pulmonary disease
Results showed that smoking and HHIP variant rs7654947 were associated with chronic obstructive pulmonary disease (COPD (显示 ARCN1 ELISA试剂盒))development and lung function decline. Moreover, we found that cigarette smoking and gene susceptibility have cooperative effects on COPD (显示 ARCN1 ELISA试剂盒) risk and lung function decline
This work supports a feasible vicious cycle in which EMPs generated during endothelial injury, in turn, aggravate endothelial damage by carrying HHIP into target ECs, contributing to the continuously deteriorating endothelial damage in the development of aGVHD. EMPs harboring HHIP would represent a potential therapeutic target for aGVHD.
HHIP expression and Gli1 (显示 GLI1 ELISA试剂盒) expression were independent prognostic factors in glioblastoma.
HHIP - candidate gene for Chronic Obstructive Pulmonary Disease identified by Genome-wide association studies.
Shh (显示 SHH ELISA试剂盒)-mediated degradation of Hhip allows cell autonomous and non-cell autonomous Shh (显示 SHH ELISA试剂盒) signaling.
HHIP might be a diagnostic or prognostic marker in glioma and help to the detection of these tumors in early stages of disease.
HHIP is located within genes previously associated with chronic obstructive pulmonary disease susceptibility.
Genetic variants in HHIP are associated with FEV1 in subjects with chronic obstructive pulmonary disease.
The HHIP gene that is known to be associated with stature in humans was strongly associated with direct calving difficulty in the present study.
PTCH1 (显示 PTCH1 ELISA试剂盒), PTCH2 and HHIP1 all contribute to ligand-dependent antagonism of sonic hedgehog (显示 SHH ELISA试剂盒) signaling.
Estradiol improves the recovery of injured nerves by downregulating the Shh (显示 SHH ELISA试剂盒) inhibitor hedgehog-interacting protein and increasing Shh (显示 SHH ELISA试剂盒)-induced angiogenesis.
hedgehog (显示 SHH ELISA试剂盒) antagonists patched 1 (显示 PTCH1 ELISA试剂盒) and Hhip1 have roels in growth and pattern of the mammalian neural tube
hypothesis for a functional link between nitric oxide and Shh (显示 SHH ELISA试剂盒) signaling and for a nonredundant role of Hip and Ptc1 (显示 PTCH1 ELISA试剂盒) in the adult brain
These data indicate that Hh signaling plays a role in adult gut (显示 GUSB ELISA试剂盒) epithelial homeostasis by regulating epithelial cell migration from crypt to villus tip and by enhancing apoptosis.
These results strongly suggest that GSK3beta (显示 GSK3b ELISA试剂盒) phosphorylates Sufu (显示 SUFUH ELISA试剂盒) to positively regulate Hedgehog (显示 SHH ELISA试剂盒) signaling in mammalian cells.
This gene encodes a member of the hedgehog-interacting protein (HHIP) family. The hedgehog (HH) proteins are evolutionarily conserved protein, which are important morphogens for a wide range of developmental processes, including anteroposterior patterns of limbs and regulation of left-right asymmetry in embryonic development. Multiple cell-surface receptors are responsible for transducing and/or regulating HH signals. The HHIP encoded by this gene is a highly conserved, vertebrate-specific inhibitor of HH signaling. It interacts with all three HH family members, SHH, IHH and DHH. Two single nucleotide polymorphisms (SNPs) near this gene are significantly associated with risk of chronic obstructive pulmonary disease (COPD). A single nucleotide polymorphism in this gene is also strongly associated with human height.
, hedgehog-interacting protein
, Hedgehog-interacting protein-like
, hedgehog interacting protein
, hedgehog-interacting protein-like