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Rat (Rattus) NRF2 ELISA Kit for Sandwich ELISA - ABIN1383619
Ahshin-Majd, Zamani, Kiamari, Kiasalari, Baluchnejadmojarad, Roghani: Carnosine ameliorates cognitive deficits in streptozotocin-induced diabetic rats: Possible involved mechanisms. in Peptides 2016
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These data suggest that EC from the Tripterygium wilfordii stem extract could diminish tau-GFP-induced neuronal death through the activation of Nrf2.
we concluded that Nrf2 plays a fundamental and conserved role in protection against acute sodium arsenite toxicity
Coptisine exerted its antioxidant activity against AAPH-induced toxicity involving in activating Akt (显示 AKT1 ELISA试剂盒) and JNK (显示 MAPK8 ELISA试剂盒)/Nrf2/NQO1 (显示 NQO1 ELISA试剂盒) pathway.
Bach1 (显示 BACH1 ELISA试剂盒) regulates the liver specificity and transience of the Nrf2a-dependent induction of hmox1a and that heme mediates this regulation through Bach1 (显示 BACH1 ELISA试剂盒) inhibition based on its level in each tissue.
The Bach1b-MafK heterodimer represses the zymogen promoters, whereas the Nrf2a-MafK heterodimer activates them.
The expression of nrf (显示 NRF1 ELISA试剂盒) genes varies temporally throughout development and nrf (显示 NRF1 ELISA试剂盒) genes are induced following a pro-oxidant exposure and are potentially cross-regulated by gene family members Nrf2a and Nrf2b (显示 GABPb ELISA试剂盒).
oxidative stress is an important mechanism of Cd-mediated injury in the zebrafish olfactory system; the Nrf2 pathway plays a protective role against cellular oxidative damage and is important in maintaining zebrafish olfactory function.
results revealed that nrf2 mutant zebrafish are viable and fertile but show an increased susceptibility to oxidative stress and electrophiles
compared the tissue-specific expression of several Nrf2 target genes in zebrafish larvae; Tissue-restricted induction was observed in the nose, gill, and/or liver for seven genes in response to Nrf2-activating compounds
Nrf2 is protective against PFOS-induced oxidative stress in zebrafish larvae.
These findings suggest that bronchiolar epithelial cells and macrophages up-regulate Nrf2 expression early in the course of infection, which results in increased expression of HO-1 (显示 HMOX1 ELISA试剂盒) within these cells.
the survival and developmental competence of embryos cultured under oxidative stress are associated with activity of the NRF2-mediated oxidative stress response pathway during bovine pre-implantation embryo development.
investigation of molecular mechanisms of microvascular complications in diabetes/hyperglycemia: Nrf2 is involved in regulation of HO-1 (显示 HMOX1 ELISA试剂盒) gene expression in aortic endothelial cells by advanced glycation end products
Lack of Nrf2 enhances susceptibility to mycotoxin-induced kidney disease.
The effects of ochratoxin A on the nuclear translocation and transactivation of the transcription factor Nrf2 as well as mRNA levels of Nrf2 target genes are reported.
Study provides evidence that KEAP1 (显示 KEAP1 ELISA试剂盒)/NRF2 (显示 GABPA ELISA试剂盒) mutations increase radioresistance and predict local tumor recurrence in radiotherapy treated LSCC patients.
NFE2L2 genetic variant is associated with heart rate variability in obese patients.
Expression of either dominant-negative or constitutively active mutants of Nrf2 (显示 GABPA ELISA试剂盒), ATF4 (显示 ATF4 ELISA试剂盒), or c-Jun (显示 JUN ELISA试剂盒) confirmed that distinct transcription units are regulated by these transcription factors.
Nrf2 (显示 GABPA ELISA试剂盒)-driven TERT (显示 TERT ELISA试剂盒) regulates pentose phosphate pathway in glioblastoma.
Nrf2 (显示 GABPA ELISA试剂盒) inhibition in Dendritic Cells (DC) in glioma-exposed microenvironment could enhance the maturation of DCs and the subsequent activation of T cells and their cytotoxicity on glioma cells.
Epigallocatechin-3-Gallate protects against Ang II (显示 AGT ELISA试剂盒)-induced HUVEC apoptosis by decreasing oxidative stress and ameliorating mitochondrial injury via activation of Nrf2 (显示 GABPA ELISA试剂盒)/casp3 (显示 CASP3 ELISA试剂盒) signaling pathway.
PRMT1 (显示 PRMT1 ELISA试剂盒) methylates Nrf2 (显示 GABPA ELISA试剂盒) protein at a single residue of arginine 437, both in vitro and in vivo. This leads to a moderate increase of its DNA-binding activity and transactivation, which subsequently protects cells against the tBHP-induced glutathione depletion and cell death. This novel modification of Nrf2 (显示 GABPA ELISA试剂盒) operates as a fine-tuning mechanism for the transcriptional activity of Nrf2 (显示 GABPA ELISA试剂盒) under oxidative stress.
Study showed that Sequestosome 1 (显示 SQSTM1 ELISA试剂盒)-mediated sequestration of Keap1 (显示 KEAP1 ELISA试剂盒) is associated with chronic activation of the Nrf2 (显示 GABPA ELISA试剂盒) stress response pathway in the autophagic vacuolar myopathie muscle; demonstrated that Nrf2 (显示 GABPA ELISA试剂盒) signaling is upregulated in autophagic muscle disorders and raise the possibility that autophagy disruption in skeletal muscle leads to dysregulation of cellular redox homeostasis.
ARF inhibits tumor growth by suppressing the ability of NRF2 (显示 GABPA ELISA试剂盒) to transcriptionally activate its target genes, including SLC7A11 (显示 SLC7A11 ELISA试剂盒), a component of the cystine/glutamate (显示 GRIN1 ELISA试剂盒) antiporter that regulates reactive oxygen species (ROS (显示 ROS1 ELISA试剂盒))-induced ferroptosis.
Keap1 (Kelch-like ECH-associated protein 1 (显示 KEAP1 ELISA试剂盒)) is an adaptor subunit of Cullin 3 (显示 CUL3 ELISA试剂盒)-based E3 ubiquitin ligase. Keap1 (显示 KEAP1 ELISA试剂盒) regulates the activity of Nrf2 (显示 GABPA ELISA试剂盒) and acts as a sensor for oxidative and electrophilic stresses.
Exposure to a xenobiotic during early development induced persistent fat accumulation via hypomethylation of lipogenic genes. Moreover, increased Nrf2 recruitment to the Srebp-1c (显示 SREBF1 ELISA试剂盒) promoter in livers of BPA (显示 DST ELISA试剂盒)-exposed mice was observed.
Novel transcriptional role of miR140-5p in the expression of Nrf2; miR (显示 MLXIP ELISA试剂盒)-140-5p protected against Cisplatin induced oxidative stress by activating Nrf2-dependent antioxidant pathway, providing a potentially therapeutic target in acute kidney injury.
Saffron (Crocus sativus) protects against myocardial ischemia-reperfusion injury in Wild Type and ApoE (显示 APOE ELISA试剂盒)((-/-)) mice via Nrf2 pathway.
High NRF2 expression is associated with Hepatocarcinogenesis.
Theraputic effects of Pirfenidone for induced pulmonary fibrosis were involved in Nrf2/Bach1 (显示 BACH1 ELISA试剂盒) equilibrium which regulated the capacity of oxidative stress.
Nrf2-driven TERT (显示 TERT ELISA试剂盒) regulates pentose phosphate pathway in glioblastoma.
Hyperactivation of Nrf2 in the initial phase of injury prevents the progression of reactive oxygen species-mediated tubular damage by inducing antioxidant enzymes and NADPH synthesis.
The results indicate that adipose-derived mesenchymal stem cells (ADSCs) can increase the survival of fat transplants through the modulation of inflammatory and oxidative responses via Nrf2 and TLR4 (显示 TLR4 ELISA试剂盒), suggesting potential strategies to improve the use of ADSCs for cell therapy.
serine 351 phosphorylation of p62 (显示 GTF2H1 ELISA试剂盒) did not enhance its binding to Keap1 (显示 KEAP1 ELISA试剂盒) or stabilise the nuclear factor erythroid 2-related factor 2 (Nrf2) transcription factor in this neuronal context. Nrf2 protein levels were markedly decreased despite transcriptional activation of the Nrf2 gene
These findings demonstrated that apigenin could prevent the D-GalN (显示 GAL ELISA试剂盒)/LPS (显示 TLR4 ELISA试剂盒)-induced liver injury in mice, and its mechanisms might be associated with the increments of Nrf-2-mediated antioxidative enzymes and modulation of PPARgamma (显示 PPARG ELISA试剂盒)/NF-kappaB (显示 NFKB1 ELISA试剂盒)-mediated inflammation.
This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters\; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been found for this gene.
, nuclear factor (erythroid-derived 2)-like 2
, nuclear factor erythroid 2-related factor 2
, NF-E2-related factor 2
, NFE2-related factor 2
, nuclear factor, erythroid derived 2, like 2
, nuclear factor erythroid-derived 2-like 2
, nuclear factor erythroid 2-like 2