anti-LMO1 (LMO1) 抗体产品概述

Full name:
anti-LIM Domain Only 1 (Rhombotin 1) 抗体 (LMO1)
在www.antibodies-online.cn可供36 LIM Domain Only 1 (Rhombotin 1) (LMO1) 抗体的9不同的供货商。 再加上,我们可以发LMO1 蛋白 (21)LMO1 试剂盒 (3)和数多这个蛋白质的别的产品。 总共62 LMO1产品已列进来了。
别名:
cb524, Dat1, LMO1, Lmo3, Rbtn-1, RBTN1, RHOM1, TTG1, wu:fb76g02, zgc:109794

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更多抗LMO1的相互作用对抗体

Mouse (Murine) LIM Domain Only 1 (Rhombotin 1) (LMO1) interaction partners

  1. SCL (显示 TAL1 抗体)-LMO1 upregulated a stem cell gene signature in DN3 thymocytes.

  2. Loss of Lmo1 repression may be one of the causes accounting for the phenotypic differences identified between the Arx((GCG)7)and Arx(432-455dup24) mouse models.

  3. SCL (显示 TAL1 抗体), LMO1, and Notch1 (显示 NOTCH1 抗体) gain of function, together with an active pre-T-cell antigen receptor (显示 PTCRA 抗体), might represent the minimum set of complementing events for the transformation of susceptible thymocytes into cancer cells

  4. Results suggest that all four members of the LIM (显示 PDLIM5 抗体)-only family -- LMO1, 2, 3, and 4 -- are important regulators of distinct developmental pathways.

  5. Lmo1 takes part in a Hox (显示 MSH2 抗体) paralogue 2-dependent network regulating anteroposterior and dorsoventral hindbrain patterning

Human LIM Domain Only 1 (Rhombotin 1) (LMO1) interaction partners

  1. LMO1 is an important oncogene (显示 RAB1A 抗体) that promotes neuroblastoma (显示 ARHGEF16 抗体) initiation, progression, and widespread metastatic dissemination.

  2. LMO1 appears to be a coactivator of AR involved in the progression of prostate cancer

  3. data suggest that genetic variants in LMO1 are associated with increased NB risk in Chinese children.

  4. a polymorphism within a super-enhancer element in the first intron of LMO1 influences neuroblastoma (显示 ARHGEF16 抗体) susceptibility through differential GATA (显示 QRSL1 抗体) transcription factor binding and direct modulation of LMO1 expression in cis (显示 CISH 抗体)

  5. LMO1 is a commonly activated tumor promoter that activates AKT (显示 AKT1 抗体) signaling in non-small cell lung cancer.

  6. LMO1 is a commonly activated tumor promoter that activates AKT (显示 AKT1 抗体) signaling in colorectal cancer and a new predictive marker for targeted therapy.

  7. results show that LMO1 is poised for expression in normal progenitors, where activation of SCL/TAL1 (显示 TAL1 抗体) together with a breakdown of epigenetic repression of LMO1 regulatory elements

  8. genetic variants within LMO1 are associated with acute lymphoblastic leukemia and identify this gene as a strong candidate for precursor B-cell leukemogenesis.

  9. data show that common polymorphisms at the LMO1 locus are strongly associated with susceptibility to developing neuroblastoma (显示 ARHGEF16 抗体), but also may influence the likelihood of further somatic alterations at this locus, leading to malignant progression

  10. 60% of transgenic mice that overexpressed both OLIG2 (显示 OLIG2 抗体) and LMO1 developed pre-T lymphoblastic lymphoma/leukemia with large thymic tumor masses.

LMO1 抗原简介

Antigen Summary

This locus encodes a transcriptional regulator that contains two cysteine-rich LIM domains but lacks a DNA-binding domain. LIM domains may play a role in protein interactions\; thus the encoded protein may regulate transcription by competitively binding to specific DNA-binding transcription factors. Alterations at this locus have been associated with acute lymphoblastic T-cell leukemia. Chromosomal rearrangements have been observed between this locus and at least two loci, the delta subunit of the T-cell antigen receptor gene and the LIM domain binding 1 gene. Alternatively spliced transcript variants have been described.

Alternative names and synonyms associated with LMO1

  • LIM domain only 1 (rhombotin 1) (LMO1) 抗体
  • Rhombotin-1 (rbtn1) 抗体
  • LIM domain only 1 (Lmo1) 抗体
  • LIM domain only 1 (lmo1) 抗体
  • rhombotin-1 (lmo1) 抗体
  • cb524 抗体
  • Dat1 抗体
  • LMO1 抗体
  • Lmo3 抗体
  • Rbtn-1 抗体
  • RBTN1 抗体
  • RHOM1 抗体
  • TTG1 抗体
  • wu:fb76g02 抗体
  • zgc:109794 抗体

Protein level used designations for LMO1

LIM domain only 1 (rhombotin 1) , Rhombotin-1 , LIM domain only protein 1 , LIM only 1 , LMO-1 , T-cell translocation protein 1 , cysteine-rich protein TTG-1 , rhombotin-1 , etID41074.7 , lmo1b , LIM domain only protein 3 , LMO-3 , LIM domain only 3 , neuronal-specific transcription factor DAT1 , dopamine-inducible LIM-domain transcription factor DAT1 , T-cell translocation gene 1 , rhombotin 1

GENE ID SPECIES
749084 Pan troglodytes
100286459 Salmo salar
109594 Mus musculus
280646 Danio rerio
245979 Rattus norvegicus
4004 Homo sapiens
527152 Bos taurus
734798 Xenopus laevis
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