Use your antibodies-online credentials, if available.
Select your species
Human CCR5 ELISA Kit for Sandwich ELISA - ABIN417539
Og?odek, Szota, Just, Mo?, Araszkiewicz: Comparison of chemokines (CCL-5 and SDF-1), chemokine receptors (CCR-5 and CXCR-4) and IL-6 levels in patients with different severities of depression. in Pharmacological reports : PR 2014
Show all 2 Pubmed References
searched for the relationship between single nucleotide polymorphism in the promoter region of the CD209, IL-10, IL-28 and 32 base pair deletion in CCR5 coding region (Delta 32) with the human predisposition to development of various clinical presentations of tick-borne encephalitis
Deficiency of CCR5 exacerbates alcoholic fatty liver disease by hepatic inflammation induced by pro-inflammatory cytokines and chemokines and oxidative stress.
CCR5-tropic HIV infection is limited to more differentiated progenitor cells with life spans that are less well understood.
Data provide evidence that CCR5 activation mediates CCL5 (显示 CCL5 ELISA试剂盒) enhances the proliferation and the invasive capacity of human breast cancer cell lines.
CCR5-Delta32 polymorphism is associated with type 1 diabetes.
this review discusses the role of CCR5 in recruitment and activation of myeloid-derived suppressor cells in melanoma
CCR5 is highly expressed in active inflammatory bowel disease, and it has positive correlation with lymphocyte grade and negative correlation with expression of beta-arrestin2 (显示 ARRB2 ELISA试剂盒).
this study shows that the dominant signature of resistance to HIV infection in this cohort of exposed but uninfected individuals was lower T-cell CCR5 expression
the level of IFNAR1, IFNAR2, and CCR5 mRNA expression was found to be significantly lower in the responders than nonresponders.Our results highlighted the significance of IFNAR and CCR5 genes in multiple sclerosis risk and the response to IFN-b therapy.
Env regions that respond to CCR5 binding was located in the gp120 (显示 ITIH4 ELISA试剂盒) alpha1 helix and in the gp41 HR1 heptad repeat and membrane-proximal external region.
Porcine vessel wall injury via balloon arthroplasty upregulates expression of CCR5 by coronary artery transmural and perivascular cells in a sequential pattern
Transcript analysis showed that antigen stimulation of WC1(+)gammadelta T cells substantially increased CCR5 expression.
CCR5 inhibition may provide a cardioprotective benefit in SIV infection by preventing cardiomyocyte CCR5 signaling.
A vaccine against CCR5 protects a subset of macaques upon intravaginal challenge with simian immunodeficiency virus SIVmac251.
CCR5 downregulation on CD4(+) T cells by TCR activation has no measurable effect on susceptibility to SAIDS.
CD4 and CD8 T cells are more vulnerable to SIV infection, indicating the the ability to express CCR5 may activate and hassten T cell death by SIV infection in vitro.
Results estimate the infectivity of CCR5-tropic simian immunodeficiency virus SIV(mac251) in the gut (显示 GUSB ELISA试剂盒).
observed a significantly higher loss of CCR5(+) CD45RA(-) CD4 (显示 CD4 ELISA试剂盒)(+) T cells in CD8 (显示 CD8A ELISA试剂盒)(+) lymphocyte-depleted macaques than in controls
Virus recovered from CA28 plasma (SHIV(CA28NP)) used both CCR5 and CXCR4 (显示 CXCR4 ELISA试剂盒) for entry, but the virus recovered from lymph node (SHIV(CA28NL)) used CXCR4 (显示 CXCR4 ELISA试剂盒) almost exclusively
Loss of CCR5 is associated with astrogliosis, amyloid-beta deposit and impaired memory function.
These findings suggest that CCR5 is likely participating in demyelination in the spinal cord in experimental autoimmune encephalomyelitis
These results demonstrate that CCR5 plays an important role in neuroplasticity, learning and memory, and indicate that CCR5 has a role in the cognitive deficits caused by HIV.
The Ccr5 is crucial in directing T cells toward the Langat virus -infected brain, as well as in suppressing neutrophil-mediated inflammation within the Central Nervous System.
This study showed that CCR5 ablation exacerbated Japanese encephalitis without altering viral burden in the extraneural and CNS tissues, as manifested by increased CNS infiltration of Ly-6C(hi) monocytes and Ly-6G(hi) granulocytes.
These results suggested that CCR5 signaling is involved in embryo loss in Toxoplasma gondii infection during early pregnancy and that apoptosis is associated with embryo loss rather than direct damage to the fetoplacental tissues.
The upregulation of CCR5 on the surface of the CD8 (显示 CD8A ELISA试剂盒)(+) T cells increases the number of contacts with Ag-bearing dendritic cells, which ultimately results in increased CD8 (显示 CD8A ELISA试剂盒)(+) T cell response to Ag rechallenge.
CCL4-CCR5 axis can contribute to breast cancer metastasis to bone by mediating the interaction between cancer cells and fibroblasts in bone cavity.
Cytokine-induced killer cells interact with tumor lysate-pulsed dendritic cells via CCR5 signaling.
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene.
C-C chemokine receptor type 5
, C-C motif chemokine receptor 5 A159A
, HIV-1 fusion coreceptor
, chemokine receptor CCR5
, C-C CKR-5
, MIP-1 alpha receptor
, chemokine (C-C) receptor 5
, chemokine C-C motif receptor 5
, C-C chemokine receptor 11 like
, CC chemokine receptor 5
, chemokine receptor 5
, CC chemokine receptor type 5
, C-C chemokine receptor 5
, chemokine (C-C motif) receptor 5
, C-C chemokine receptor 5 like
, C-C chemokine receptor type 2
, C-C chemokine receptor type 5-like