anti-FOXO (FOXO) 抗体产品概述

Full name:
anti-Forkhead Box, Sub-Group O 抗体 (FOXO)
在www.antibodies-online.cn可供4 Forkhead Box, Sub-Group O (FOXO) 抗体的2不同的供货商。 总共4 FOXO产品已列进来了。
别名:
3143, Afx, anon-WO0118547.374, cg3143, dfoxo, Dmel\\CG3143, DmQ95V5, fd88A, FKHR, foxo, Q95V55
列出全部抗体 基因 基因ID UniProt
FOXO 41709 Q95V55

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抗Fruit Fly (Drosophila melanogaster) FOXO 抗体:

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更多抗FOXO的相互作用对抗体

Fruit Fly (Drosophila melanogaster) Forkhead Box, Sub-Group O (FOXO) interaction partners

  1. This study highlights D. melanogaster as a model of cardiac aging and FOXO as a tightly regulated mediator of proteostasis and heart performance over time.

  2. elevated expression of Pav-KLP (显示 KIF1B 抗体) underlies transport and plasticity phenotypes in pathway mutants, indicating that Toll (显示 TLR4 抗体)-6-FoxO signaling promotes MT dynamics by limiting Pav-KLP (显示 KIF1B 抗体) expression.

  3. FoxO regulates dendrite structure and function and FoxO-mediated pathways control microtubule dynamics and polarity.

  4. identify the regions of the Hsp70 promoter essential for FOXO-dependent transcription using in vitro methods and find a physiological role for FOXO-dependent expression of heat shock proteins in vivo.

  5. a previously unknown role of dFoxO in promoting Wg signaling, and that a dFoxO-Arm complex is likely involved in their mutual functions, e.g. cell death.

  6. subtle manipulation of foxo through Akt1 (显示 AKT1 抗体) can enhance survival during adverse nutrient conditions in Drosophila.

  7. Inhibition of the mitochondrial TRAP1 (显示 TRAP1 抗体) generates a retrograde cell protective signal from mitochondria to the nucleus in a FOXO-dependent manner.

  8. Pll physically interacts with dFoxO and phosphorylates dFoxO directly. This study not only identifies a previously unknown physiological function of pll in cell death, but also shed light on the mechanism of IRAKs in tumorigenesis.

  9. KDM5 interacts with Foxo to modulate cellular levels of oxidative stress.KDM5 interacts with the lysine deacetylase HDAC4 (显示 HDAC4 抗体) to promote Foxo deacetylation, which affects Foxo DNA binding.

  10. Fasting increases survival to cold in FOXO mutant Drosophila melanogaster.

FOXO 抗原简介

Antigen Summary

Transcription factor involved in the regulation of the insulin signaling pathway. Consistently activates both the downstream target Thor\d4EBP and the feedback control target InR. Involved in negative regulation of the cell cycle, modulating cell growth and proliferation. In response to cellular stresses, such as nutrient deprivation or increased levels of reactive oxygen species, foxo is activated and inhibits growth through the action of target genes such as Thor. Foxo activated in the adult fat body can regulate lifespan in adults\; an insulin peptide itself may function as one secondary messenger of insulin-regulated aging. Also regulates Lip4, homolog of human acid lipases, thereby acting as a key modulator of lipid metabolism by insulin signaling and integrates insulin responses to glucose and lipid homeostasis.

Alternative names and synonyms associated with FOXO

  • forkhead box, sub-group O (foxo) 抗体
  • 3143 抗体
  • Afx 抗体
  • anon-WO0118547.374 抗体
  • cg3143 抗体
  • dfoxo 抗体
  • Dmel\\CG3143 抗体
  • DmQ95V5 抗体
  • fd88A 抗体
  • FKHR 抗体
  • foxo 抗体
  • Q95V55 抗体

Protein level used designations for FOXO

CG3143-PB , CG3143-PC , CG3143-PF , CG3143-PG , forkhead Box O , forkhead bOX-containing protein, subfamily O , forkhead box , forkhead box sub-group O , forkhead box type O , forkhead box, subgroup O , forkhead transcription factor , foxo-PB , foxo-PC , foxo-PF , foxo-PG

GENE ID SPECIES
41709 Drosophila melanogaster
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