CDK9 (CDK9) ELISA试剂盒产品概述

Full name:
Cyclin-Dependent Kinase 9 ELISA试剂盒 (CDK9)
在www.antibodies-online.cn可供19 Cyclin-Dependent Kinase 9 (CDK9) ELISA试剂盒的2不同的供货商。 再加上,我们可以发CDK9 抗体 (149)CDK9 蛋白 (12)和数多这个蛋白质的别的产品。 总共186 CDK9产品已列进来了。
别名:
C-2k, CDC2L4, cdk9, CG5179, CTK1, Dmel\\CG5179, P-TEF, P-TEFb, PITALRE, PTefb, TAK, wu:fb22e09, wu:fc06c02

适于 CDK9 相互作用对的更多 ELISA 试剂盒

Fruit Fly (Drosophila melanogaster) Cyclin-Dependent Kinase 9 (CDK9) interaction partners

  1. actin (显示 ACTB ELISA试剂盒) participates in transcription elongation by recruiting Cdk9,a catalytic subunit of P-TEFb, for phosphorylation of the Pol II C-terminal domain, and the actin (显示 ACTB ELISA试剂盒)-Cdk9 interaction promotes chromatin remodeling

  2. Genetic transcription and RNA processing of PTefb kinase is coordinated on heat shock genes.

  3. Cdk9 is required for heat shock gene expression, histone methylation and elongation factor (显示 TSFM ELISA试剂盒) recruitment.

Human Cyclin-Dependent Kinase 9 (CDK9) interaction partners

  1. RBPJ (显示 RBPJ ELISA试剂盒) links MYC (显示 MYC ELISA试剂盒) and transcriptional control through CDK9 in brain tumors, providing potential nodes of fragility for therapeutic intervention, potentially distinct from NOTCH (显示 NOTCH1 ELISA试剂盒)

  2. Chemical degrader of BET bromodomain proteins, dBET6, led to the unexpected identification of BRD4 (显示 BRD4 ELISA试剂盒) as master regulator of global transcription elongation in acute T-cell leukemia. BRD4 (显示 BRD4 ELISA试剂盒) loss does not directly affect CDK9 localization.

  3. H1 variant interphase phosphorylation is dynamically regulated in a site-specific and gene-specific fashion during pluripotent cell differentiation, and that enrichment of pS187-H1.4 at genes is positively related to their transcription. H1.4-S187 is likely to be a direct target of CDK9 during interphase, suggesting the possibility that this particular phosphorylation may contribute the release of paused RNA pol II

  4. CDK9 is a player in the DNA damage response and is consistent with its participation in homology-directed recombination pathway by modulating BRCA1 response.

  5. HSP90 (显示 HSP90 ELISA试剂盒) downstream HSF1 (显示 HSF1 ELISA试剂盒) gives positive feedback to the reactivation process through binding to cyclin-dependent kinase 9 (CDK9) and preventing it from undergoing degradation by the proteasome.

  6. Quantitative measurement of the molecular interactions among Tat (显示 TAT ELISA试剂盒), CycT1 (显示 CCNT1 ELISA试剂盒) and CDK9 has showed that any third molecule enhances the binding between the other two molecules. These findings suggest that each component of the Tat:P-TEFb (显示 TEF ELISA试剂盒) complex stabilizes the overall complex, thereby supporting the efficient transcriptional elongation during viral RNA synthesis.

  7. We could conclude that there are many small molecules that bind to CDK9, but their lack of selectivity against other CDKs do not allow them to get to the clinical use

  8. Findings indicate that cyclin-dependent kinase 9 (CDK9) represent an important role for inflammation in the pathogenesis of atherosclerosis.

  9. Studies indicate that CDK9 regulates the genetic transcription at the early-elongation checkpoint close to poly(A) sites just before a functional polyadenylated mRNA is produced.

  10. Our findings suggest a potential role of CDK9 in the radiation response of head and neck squamous cell carcinoma cells

Xenopus laevis Cyclin-Dependent Kinase 9 (CDK9) interaction partners

  1. Full-length cDNA, morpholinos, and mutagenesis rescue constructs of cdk9L were used. Cdk9.S, Cdk9.L andCyclinT1 were expressed in the neural plate and neural plate border of neurula stage embryos and in the neural-crest-derived branchial arteries at the tailbud stage. Cdk9 knockdown causes an increase in RNA Pol II occupance and pausing of c-myc (显示 MYC ELISA试剂盒) which regulates neural crest specification.

Pig (Porcine) Cyclin-Dependent Kinase 9 (CDK9) interaction partners

  1. inhibition of CDK9 abrogated global transcriptional activity and rRNA production. Collectively, our data suggested that P-TEFb (显示 CCNT1 ELISA试剂盒) kinase activity is crucial for oocyte maturation, embryo development and regulation of RNA transcription in pig.

Mouse (Murine) Cyclin-Dependent Kinase 9 (CDK9) interaction partners

  1. identified cyclin-dependent kinase 9 (Cdk9) as required for hepatocellular carcinoma disease maintenance

  2. This study demonstrates that Ikaros (显示 IKZF1 ELISA试剂盒) directly interacts with GATA1 (显示 GATA1 ELISA试剂盒), GATA2 (显示 GATA2 ELISA试剂盒), and GATA3 (显示 GATA3 ELISA试剂盒) as well as Cdk9/P-TEFb through specific protein domains.

  3. Data show that the minimal 90-amino acid AF9 (显示 MLLT3 ELISA试剂盒) fragment in MLL (显示 MLL ELISA试剂盒)-AF9 (显示 MLLT3 ELISA试剂盒) retains an ability to form higher order complexes with AF4*P-TEFb (显示 CCNT1 ELISA试剂盒) and with DOT1 (显示 DOT1L ELISA试剂盒).

  4. Data show that the CDK9 and cyclin T1 (显示 CCNT1 ELISA试剂盒) subunits of P-TEFb (显示 CCNT1 ELISA试剂盒) are present in mouse oocytes and preimplantation embryos, and that CDK9 is essential for embryonic genome activation in the mouse.

  5. The present study examined whether Cdk9 forms a complex with GATA4 (显示 GATA4 ELISA试剂盒) in mouse embryonic stem cells and is involved in their differentiation into cardiomyocytes.

  6. Data report that a second cdk9 isoform, termed cdk9-55, plays a fundamental role in muscle regeneration and differentiation in vivo.

  7. role in activating MyoD (显示 MYOD1 ELISA试剂盒)-dependent transcription

  8. CDK9 has the intrinsic property to shuttle between nucleus and cytoplasm, and enhanced expression of cyclin T1 (显示 CCNT1 ELISA试剂盒) promotes its nuclear localization.

  9. chronic activation of Cdk9 causes not only cardiomyocyte enlargement but also defective mitochondrial function, via diminished PGC-1 (显示 PPARGC1A ELISA试剂盒) transcription, and a resulting susceptibility to apoptotic cardiomyopathy

  10. PPARgamma (显示 PPARG ELISA试剂盒)-cdk9 interaction results in increased transcriptional activity of PPARgamma (显示 PPARG ELISA试剂盒) and therefore increased adipogenesis.

Zebrafish Cyclin-Dependent Kinase 9 (CDK9) interaction partners

  1. CDK9 clearly plays a fundamental role in early cellular growth and proliferation.

  2. Pharmacological and genetic results present evidence that CDK9 is involved in the resolution of neutrophil-dependent inflammation.

  3. The balance of Cdk9 and Larp7 (显示 LARP7 ELISA试剂盒) plays a key role in cardiomyocyte proliferation and response to injury

CDK9 抗原简介

Antigen Summary

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.

Alternative names and synonyms associated with CDK9

  • Cyclin-dependent kinase 9 (Cdk9) Elisa Kit
  • cyclin-dependent kinase 9 (CDK9) Elisa Kit
  • cyclin-dependent kinase 9 (cdk9) Elisa Kit
  • cyclin-dependent kinase 9 (Cdk9) Elisa Kit
  • cyclin-dependent kinase 9 (cdk9-a) Elisa Kit
  • cyclin-dependent kinase 9 (CDC2-related kinase) (Cdk9) Elisa Kit
  • cyclin-dependent kinase 9 (CDC2-related kinase) (cdk9) Elisa Kit
  • cyclin-dependent kinase 9-like (LOC100855805) Elisa Kit
  • C-2k Elisa Kit
  • CDC2L4 Elisa Kit
  • cdk9 Elisa Kit
  • CG5179 Elisa Kit
  • CTK1 Elisa Kit
  • Dmel\\CG5179 Elisa Kit
  • P-TEF Elisa Kit
  • P-TEFb Elisa Kit
  • PITALRE Elisa Kit
  • PTefb Elisa Kit
  • TAK Elisa Kit
  • wu:fb22e09 Elisa Kit
  • wu:fc06c02 Elisa Kit

Protein level used designations for CDK9

CG5179-PA , Cdk9-PA , Cyclin-dependent kinase9 2.7 , p43 PITALRE , positive transcription elongation factor b , positive transcription elongation factor b, small subunit , cyclin-dependent kinase 9 (CDC2-related kinase) , cell division protein kinase 9 , CDC2-related kinase , cell division cycle 2-like protein kinase 4 , serine/threonine protein kinase PITALRE , serine/threonine-protein kinase PITALRE , tat-associated kinase complex catalytic subunit , cell division protein kinase 9-A , cyclin-dependent kinase 9-A , cyclin-dependent kinase 9

GENE ID SPECIES
37586 Drosophila melanogaster
464755 Pan troglodytes
448039 Xenopus (Silurana) tropicalis
1025 Homo sapiens
362110 Rattus norvegicus
735101 Xenopus laevis
417226 Gallus gallus
100307051 Sus scrofa
520580 Bos taurus
100725846 Cavia porcellus
101109788 Ovis aries
107951 Mus musculus
321602 Danio rerio
100855805 Canis lupus familiaris
491325 Canis lupus familiaris
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