CDK6 (CDK6) ELISA试剂盒产品概述

Full name:
Cyclin-Dependent Kinase 6 ELISA试剂盒 (CDK6)
在www.antibodies-online.cn可供13 Cyclin-Dependent Kinase 6 (CDK6) ELISA试剂盒的6不同的供货商。 再加上,我们可以发CDK6 抗体 (256)CDK6 蛋白 (13)和数多这个蛋白质的别的产品。 总共297 CDK6产品已列进来了。
5830411I20, AI504062, CDK6, Crk2, PLSTIRE
list all ELISA KIts 基因 基因ID UniProt
CDK6 1021 Q00534
小鼠 CDK6 CDK6 12571 Q64261
大鼠 CDK6 CDK6 114483  



引用最多的CDK6 ELISA试剂盒

  1. Human CDK6 ELISA Kit for Sandwich ELISA - ABIN417792 : Berenjian, Hu, Abedi-Valugerdi, Hassan, Bashir Hassan, Morein: The nanoparticulate Quillaja saponin KGI exerts anti-proliferative effects by down-regulation of cell cycle molecules in U937 and HL-60 human leukemia cells. in Leukemia & lymphoma 2014 (PubMed)

适于 CDK6 相互作用对的更多 ELISA 试剂盒

Human Cyclin-Dependent Kinase 6 (CDK6) interaction partners

  1. Describe a regulatory loop miR (显示 MLXIP ELISA试剂盒)-218-CDK6/CyclinD1-E2F1 (显示 E2F1 ELISA试剂盒) whose disruption may contribute to cell cycle progression in gastric cancer.

  2. Specific E2Fs also have prognostic value in breast cancer, independent of clinical parameters. We discuss here recent advances in understanding of the RB-E2F (显示 E2F1 ELISA试剂盒) pathway in breast cancer. We also discuss the application of genome-wide genetic screening efforts to gain insight into synthetic lethal interactions of CDK4/6 (显示 CDK4 ELISA试剂盒) inhibitors in breast cancer for the development of more effective combination therapies.

  3. The deletion of CBX3 (显示 CBX3 ELISA试剂盒) directly enforces the expression of CDK6 and p21 (显示 CDKN1A ELISA试剂盒).

  4. Amplification of the G1-S regulatory genes, CCNE1, CCND1 and CdK6, represent an early event, which precedes ERBB2, EGFR, or KRAS amplification in gastric adenocarcinoma.

  5. CDK6-mediated suppression of CD25 (显示 IL2RA ELISA试剂盒) is required for initiation of T-ALL by activated Notch1 (显示 NOTCH1 ELISA试剂盒)

  6. CDK6 overexpression is associated with cancer.

  7. High CDK6 expression is associated with Melanoma.

  8. Palbociclib can overcome mutations in cyclin dependent kinase 6 that break hydrogen bonds between the drug and the protein

  9. Our study proved that the CDK6 gene is a target of miR (显示 MLXIP ELISA试剂盒)-637, and demonstrated the regulatory association between miR (显示 MLXIP ELISA试剂盒)-637 and CDK6

  10. we verified that miR (显示 MLXIP ELISA试剂盒)-892b regulates the p19ARF/cyclin D1 (显示 CCND1 ELISA试剂盒)/CDK6 and Sp-1 (显示 PSG1 ELISA试剂盒)/MMP-9 (显示 MMP9 ELISA试剂盒) signaling networks in bladder cancer cells and may provide a treatment option for advanced-stage bladder cancers.

Mouse (Murine) Cyclin-Dependent Kinase 6 (CDK6) interaction partners

  1. PD 0332991 (PD), an FDA (显示 FDA ELISA试剂盒)-approved selective inhibitor of cyclin-dependent kinase 4/6 (CDK4/6 (显示 CDK4 ELISA试剂盒)), prevents radiation-induced lethal intestinal injury in mice. Treating mice with PD or a structurally distinct CDK4/6 (显示 CDK4 ELISA试剂盒) inhibitor prior to radiation blocked proliferation and crypt apoptosis and improved crypt regeneration.

  2. CDK6-mediated suppression of CD25 (显示 IL2RA ELISA试剂盒) is required for initiation of T-ALL by activated Notch1 (显示 NOTCH1 ELISA试剂盒). . Pharmacologic inhibition of CDK6 kinase induces CD25 (显示 IL2RA ELISA试剂盒) and RUNX1 (显示 RUNX1 ELISA试剂盒) expression, cell cycle arrest and apoptosis in mouse and human T-ALL.

  3. Fbxo7 (显示 FBXO7 ELISA试剂盒)-deficient immature thymocytes failed to undergo expansion in the thymus due to a lack of Cdk6 activity, while mature T cells showed enhanced proliferative capacity upon T-cell receptor engagement due to reduced p27 (显示 CDKN1B ELISA试剂盒) levels. These studies reveal differential cell cycle regulation by Fbxo7 (显示 FBXO7 ELISA试剂盒) at different stages in T-cell development.

  4. Taken together, our results suggested that microRNA-33 enhanced the replicative senescence of MEFs potentially by suppressing CDK6 expression.

  5. Data show that E11/glycoprotein 38 (显示 PDPN ELISA试剂盒)(GP38 (显示 PDPN ELISA试剂盒)) was up-regulated upon SEMA3A (显示 SEMA3A ELISA试剂盒) stimulation, and cyclin-dependent kinase 6 (CDK6) was down-regulated in a time-dependent manner.

  6. Notch3 (显示 NOTCH3 ELISA试剂盒) transcription and growth of lymphoma cells was dependent on CDK6.

  7. CDK6 is an important regulator of stem cell activation and an essential component of a transcriptional complex that suppresses Egr1 (显示 EGR1 ELISA试剂盒) in hematopoietic and leukemic stem cell activation

  8. Cdk4 (显示 CDK4 ELISA试剂盒) and Cdk6 cooperate in hematopoietic tumor development and suggest a role for Cdk6 in sequestering INK4 proteins away from Cdk4 (显示 CDK4 ELISA试剂盒).

  9. Cdk6/Ccnd1 (显示 CCND1 ELISA试剂盒) overexpression inhibits chondrocyte maturation and enhances G1/S transition by phosphorylating pRb (显示 PGR ELISA试剂盒); the chondrocytes then undergo p53 (显示 TP53 ELISA试剂盒)-dependent apoptosis

  10. p107 (显示 RBL1 ELISA试剂盒) retinoblastoma protein is regulated by Cdk6/Ccnd1 (显示 CCND1 ELISA试剂盒) in growth plates.

Cow (Bovine) Cyclin-Dependent Kinase 6 (CDK6) interaction partners

  1. the T-1075C SNP of bovine CDK6 is significantly associated with body length and heart girth

CDK6 抗原简介

Antigen Summary

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Alternative names and synonyms associated with CDK6

  • cyclin-dependent kinase 6 (CDK6) Elisa Kit
  • cyclin-dependent kinase 6 (Cdk6) Elisa Kit
  • 5830411I20 Elisa Kit
  • AI504062 Elisa Kit
  • CDK6 Elisa Kit
  • Crk2 Elisa Kit
  • PLSTIRE Elisa Kit

Protein level used designations for CDK6

cyclin-dependent kinase 6 , cell division protein kinase 6-like , cell division protein kinase 6 , serine/threonine-protein kinase PLSTIRE , CR2 protein kinase

746968 Pan troglodytes
100454924 Pongo abelii
1021 Homo sapiens
12571 Mus musculus
114483 Rattus norvegicus
609920 Canis lupus familiaris
511754 Bos taurus
420558 Gallus gallus
100518921 Sus scrofa
100009040 Oryctolagus cuniculus
100061625 Equus caballus
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