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Mouse (Murine) beta 2 Adrenergic Receptor ELISA Kit for Sandwich ELISA - ABIN427043
Zapater, Gómez-Hurtado, Peiró, González-Navajas, García, Giménez, Moratalla, Such, Francés: Beta-adrenergic receptor 1 selective antagonism inhibits norepinephrine-mediated TNF-alpha downregulation in experimental liver cirrhosis. in PLoS ONE 2012
Zebrafish larvae lacking beta1AR (显示 ADRB1 ELISA试剂盒) expression by morpholino knockdown displayed lower heart rates than control fish, whereas larvae deficient in both beta2aAR and beta2bAR expression exhibited significantly higher heart rates than controls.
S1928A KI mice failed to induce long-term potentiation in response to prolonged theta-tetanus (PTT-LTP (显示 SCP2 ELISA试剂盒)), a form of synaptic plasticity that requires Cav1.2 (显示 CACNA1C ELISA试剂盒) and enhancement of its activity by the beta2-adrenergic receptor (beta2AR)-cAMP-PKA cascade.
activation of beta2AR decreased cerebral amyloid plaques through the up-regulation of alpha-secretase activity and by decreasing the phosphorylation of APP (显示 APP ELISA试剂盒) at Thr668
Together, these data indicate that high-fat diet promotes phosphorylation of the beta2 AR, contributing to impairment of cardiac contractile reserve before cardiac structural and functional remodelling, suggesting that early intervention in the insulin (显示 INS ELISA试剂盒)-adrenergic signalling network might be effective in prevention of cardiac complications in diabetes
beta2-AR deletion is associated to selective hepatic insulin (显示 INS ELISA试剂盒) resistance and preserved skeletal muscle insulin (显示 INS ELISA试剂盒) sensitivity.
The diurnal variation of the humoral immune response was dependent on beta2AR-mediated neural signals and was diminished when lymphocyte recirculation through lymph nodes was stopped.
knocking out of the beta1/2 (显示 TFAP2B ELISA试剂盒) receptor significantly diminished the ST25 acupuncture-induced inhibition of gastric motility and jejunal motility without significantly altering the enhancement of colonic motility induced by acupuncture at ST25.
The authors show that phosphorylation of S1928 displaces the beta-2 adrenergic receptor from Cav1.2 (显示 CACNA1C ELISA试剂盒) upon beta-adrenergic stimulation rendering Cav1.2 (显示 CACNA1C ELISA试剂盒) refractory for several minutes from further beta-adrenergic stimulation.
The Galphas (显示 GNAS ELISA试剂盒) and Galphaq (显示 GNAQ ELISA试剂盒) peptides adopt different orientations in beta2-AR and V1AR (显示 AVPR1A ELISA试剂盒), respectively. The beta2-AR/Galphas (显示 GNAS ELISA试剂盒) peptide interface is dominated by electrostatic interactions, whereas the V1AR (显示 AVPR1A ELISA试剂盒)/Galphaq (显示 GNAQ ELISA试剂盒) peptide interactions are predominantly hydrophobic.
Thus the beta2AR acts as a double-edged sword: increasing TAS2R14 cell surface expression, but when activated by beta-agonist, partially offsetting the expression phenotype by direct receptor:receptor desensitization of TAS2R14 function.
Data show that inhibitory (Galphai2 (显示 GNAI2 ELISA试剂盒)) and stimulatory (GalphasL) G-protein subunits produced minor atrophic and hypertrophic changes in muscle mass, and Galphai2 (显示 GNAI2 ELISA试剂盒) over-expression prevented AAV:beta2-adrenoceptor (beta2-AR) mediated hypertrophy.
These results indicate dependence of hepatic glucocorticoid and adrenergic receptors on stage of maturation in neonatal calves and emphasize the association of alpha1-adrenergic receptor and glucocorticoid receptor (显示 NR3C1 ELISA试剂盒) with neonatal glucose and lipid metabolism.
ADRb2 shows lipid scrambling activity.
relationship between luteal concentrations of oxytocin (OT), noradrenaline (NA), progesterone (P4), oxytocin receptors (OT-R (显示 OXTR ELISA试剂盒)) and beta(2)-adrenoreceptors (beta(2)-R) gene expression and their protein level throughout the estrous cycle
a substantial proportion of the beta2AR produced is non-functional and VCP (显示 vcp ELISA试剂盒) plays a key role in the maturation and trafficking of the beta2AR.
The protein kinase (显示 CDK7 ELISA试剂盒) activity of PI3K (显示 PIK3CA ELISA试剂盒) phosphorylates serine residue 70 on Src (显示 SRC ELISA试剂盒) to enhance its activity and induce EGFR (显示 EGFR ELISA试剂盒) transactivation following betaAR stimulation.
The data suggested that Arg/Arg homozygosity at codon 16 of the ADRB2 gene predisposes patients to a clinically more severe course of chronic obstructive pulmonary disease
using single-molecule fluorescence resonance energy transfer imaging, we examine TM6 movements in the beta2 adrenergic receptor (beta2AR) upon exposure to orthosteric ligands with different efficacies, in the absence and presence of the Gs heterotrimer
The frequency of the genotypes and alleles of rs1042711 in ADRB2 showed a significant difference between the COPD (显示 ARCN1 ELISA试剂盒) and control groups. TT genotype and TG and TC haplotypes of rs1042711 in ADRB2 are related to pulmonary function in COPD (显示 ARCN1 ELISA试剂盒) patients. TT genotype of rs1042711 in ADRB2 and smoking amount are risk factors for COPD (显示 ARCN1 ELISA试剂盒) development.
Results provide further evidence for the interaction of rs2400707, and other SNPs within the ADRB2 gene, with childhood trauma in relation to risk for posttraumatic stress disorder.
Gln27Glu polymorphism of ADRB2 influences exercise-induced vascular adaptation in patients with acute coronary syndrome.
Data suggest that ADRB2 (beta2 adrenergic receptor) activation (as illustrated by epinephrine and nor epinephrine) leads to robust calcium ion mobilization from intracellular stores in endoplasmic reticulum via activation of phosphoinositide phospholipase C (PLC (显示 PIPLC ELISA试剂盒)) and opening of inositol trisphosphate receptor (IP3R (显示 ITPR1 ELISA试剂盒)).
Data suggest that post-translational modifications (phosphorylation, oxidation, and nitrosylation) of RyR2 (ryanodine receptor 2 (显示 RYR2 ELISA试剂盒)) occur downstream of production of amyloid beta-peptides through ADRB2 (beta2-adrenergic receptor) Ca2 (显示 CA2 ELISA试剂盒)+ signaling cascade that activates PKA (protein kinase A).
ADRB2 SNPs might be a genetic risk factor for dyslipidemia in the Chinese hypertensive patients. the A46G polymorphism was significantly associated with the elevated risk of hypertriglyceridemia. Haplotype analysis showed that the TAC (显示 IL2RA ELISA试剂盒) haplotype carrying frequent alleles of the three SNPs played a reduced role in hypertriglyceridemia risk and the TGC (显示 TGM2 ELISA试剂盒) haplotype carrying rare allele of A46G expressed a significant risk effe
A persistent B2R (显示 BDKRB2 ELISA试剂盒)-beta2AR heterodimer was confirmed in bradykinin-stimulated and non-stimulated left ventricular myocardium. BK transactivation of beta2AR enhanced beta2AR-mediated release of tPA (显示 PLAT ELISA试剂盒).
Prolactin (显示 PRL ELISA试剂盒) infusion brought about the inhibition of a vasodilatory beta(2)-adrenergic receptor-mediated effect related to the NO intracellular pathway
Intracoronary intermedin (显示 ADM2 ELISA试剂盒) 1-47 augments cardiac perfusion and function in anesthetized pigs: role of calcitonin (显示 CALCA ELISA试剂盒) receptors and beta-adrenoreceptor-mediated nitric oxide release.
The results imply ADRB-2-mediated actions in the development of primate follicles
This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.
adrenergic receptor beta-2
, adrenergic, beta-2-, receptor, surface
, beta-2 adrenergic receptor
, beta-2b-adrenergic receptor
, beta-2 adrenoceptor
, beta-2 adrenoreceptor
, beta 2-AR
, adrenergic receptor beta 2
, adrenergic, beta-2, receptor, surface
, catecholamine receptor
, beta2-adrenergic receptor
, Adrenergic beta 2- receptor surface
, adrenergic receptor, beta 2
, Beta-2 adrenergic receptor
, Beta-2 adrenoceptor
, Beta-2 adrenoreceptor
, beta 2 adrenergic receptor
, beta-2-adrenergic receptor