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Human alpha Fetoprotein Protein expressed in Human - ABIN934756
Lee, Nguyen, Sim: A nanoplasmonic biosensor for label-free multiplex detection of cancer biomarkers. in Biosensors & bioelectronics 2015
Show all 2 Pubmed References
Human alpha Fetoprotein Protein expressed in Cell culture - ABIN573558
Mikhaylova, Schumacher, Borutzki, Neumann, Macharadze, El-Mousleh, Wahle, Zenclussen, Kreutz: Analysis of Y-P30/Dermcidin expression and properties of the Y-P30 peptide. in BMC research notes 2014
Human alpha Fetoprotein Protein expressed in Human - ABIN934453
Lee, Lee: Regression of hepatocarcinoma cells using RNA aptamer specific to alpha-fetoprotein. in Biochemical and biophysical research communications 2012
Human alpha Fetoprotein Protein expressed in Human - ABIN377076
Jee, Ang, Cha, Ang, Ling, Lim, Lee: Combinatorial bead-based peptide libraries improved for rapid and robust screenings. in Combinatorial chemistry & high throughput screening 2014
endogenous AFP expression in the perinatal liver is reduced in the absence of beta-catenin (显示 CTNNB1 蛋白), suggesting that beta-catenin (显示 CTNNB1 蛋白) regulates AFP during liver development.
Findings indicate that AFP expressed under experimental cryptorchid conditions plays a role as a regulatory factor in spermatogenesis and in hepatic generation.
AFP mRNA and VEGF-C (显示 VEGFC 蛋白) mRNA in peripheral blood were significantly correlated with recurrence and metastasis of hepatocellular carcinoma.
A DEHP treatment-induced phenotype was identified with lack of glycogen (显示 GYS1 蛋白) accumula-tion and intracytoplasmic localization of beta-catenin (显示 CTNNB1 蛋白) which was associated with increased AFP gene expression.
The deficits observed in parental behavior of AFP knockout females could not be explained by any changes in olfactory function, novelty recognition or anxiety
Foxa1 (显示 FOXA1 蛋白) acts as a pioneer transcription factor in de novo activation of Afp, by exploiting a lack of methylation at juxtaposed transposed elements
The level of AFP mRNA in peripheral blood may indicate recurrence and/or metastasis after curative resection of hepatocellular carcinoma.
AFP affects cell proliferation by binding its receptor to trigger the signal transduction pathway of cAMP-PKA and alter the expression of K- ras (显示 HRAS 蛋白) p21 genes
A murine Nkx2.8 (显示 NKX2-6 蛋白) was isolated from the Hepal-6 cell line and showed oligonucleotide binding competitive with fetoprotein transcription factor (显示 NR5A2 蛋白).
The mouse alpha-fetoprotein promoter is repressed in HepG2 hepatoma cells by hepatocyte nuclear factor-3 (显示 FOXA1 蛋白)
BWS (显示 CDKN1C 蛋白) registries and prospective clinical studies will assess the most appropriate means to screen for hepatoblastoma, whether aFP-screened patients have additional survival benefit over patients screened by US only, and whether the outcome is improved by earlier detection
p55PIK significantly stimulated the expression of AFP by activating NF-kappaB (显示 NFKB1 蛋白) signaling pathway in hepatocellular carcinoma cells.
Irregular MIP (显示 TNPO1 蛋白) pattern by CEUS and high level of serum AFP-L3 were independent risk factors for poor outcome after successful RFA (显示 RPA1 蛋白). The Patients with these findings should be considered as special high-risk group in early-stage HCC (显示 FAM126A 蛋白).
our data suggest that HBeAg seroconversion and liver cirrhosis are associated with the occurrence of HCC (显示 FAM126A 蛋白) and that a surveillance system with regular measurement of AFP to watch for the occurrence of HCC (显示 FAM126A 蛋白) may be mandatory for children and young patients with chronic HBV infection.
We could demonstrate in our cohort the superior detection of early stage HCC (显示 FAM126A 蛋白) with the combined use of the respective biomarkers and in particular GALAD even in AFP-negative tumors.
A correlation was found between serum AFP concentration and age in extremely low-birthweight infants (ELBWI), and the 95%CI of serum AFP concentration was determined for ELBWI up to 2 years after birth.
rAFP promoted growth of the human HCC (显示 FAM126A 蛋白) cells, antagonize paclitaxel inhibition of HCC (显示 FAM126A 蛋白) cell proliferation, suppress expression of active caspase-3 (显示 CASP3 蛋白), and promote expression of Ras and survivin (显示 BIRC5 蛋白).
Measurements of serum alpha-fetoprotein (AFP) levels could be helpful in detecting progression or recurrence in treated patients with hepatitis B virus (HBV) - hepatocellular carcinoma (HCC (显示 FAM126A 蛋白)) and normal alanine aminotransferase (显示 ALT 蛋白) (ALT).
AFP mRNA level is in enriched circulating tumor cells from patients with metastatic hepatocellular carcinoma.
High serum AFP levels were significantly associated with the prevalence of metabolic syndrome in a Chinese asymptomatic population.
Equine alpha-fetoprotein seems to be an important indicator of fetal well-being in horses.
This study confirmed that alpha-fetoprotein (AFP) is present in the fetal fluids of mares during the third trimester of pregnancy; experimentally induced placentitis was associated with an elevation in maternal plasma concentrations of AFP.
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
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