alpha Fetoprotein 蛋白 (AFP)产品概述

Full name:
alpha-Fetoprotein 蛋白 (AFP)
在www.antibodies-online.cn可供68 alpha-Fetoprotein (AFP) 蛋白的13不同的供货商。 再加上,我们可以发alpha Fetoprotein 抗体 (1100)alpha Fetoprotein 试剂盒 (117)和数多这个蛋白质的别的产品。 总共1304 alpha Fetoprotein产品已列进来了。
列出全部蛋白 基因 基因ID UniProt
AFP 11576 P02772
AFP 174 P02771
AFP 24177  


按照种类alpha Fetoprotein 蛋白 (AFP)


引用最多的alpha Fetoprotein 蛋白

  1. Human alpha Fetoprotein Protein expressed in Human Cells - ABIN2005088 : Tomasi: Structure and function of alpha-fetoprotein. in Annual review of medicine 1977 (PubMed)

  2. Human alpha Fetoprotein Protein expressed in Human - ABIN934455 : Lee, Lee: Regression of hepatocarcinoma cells using RNA aptamer specific to alpha-fetoprotein. in Biochemical and biophysical research communications 2012 (PubMed)

  3. Human alpha Fetoprotein Protein expressed in Cell culture - ABIN573558 : Mikhaylova, Schumacher, Borutzki, Neumann, Macharadze, El-Mousleh, Wahle, Zenclussen, Kreutz: Analysis of Y-P30/Dermcidin expression and properties of the Y-P30 peptide. in BMC research notes 2014 (PubMed)

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Mouse (Murine) alpha-Fetoprotein (AFP) interaction partners

  1. endogenous AFP expression in the perinatal liver is reduced in the absence of beta-catenin (显示 CTNNB1 蛋白), suggesting that beta-catenin (显示 CTNNB1 蛋白) regulates AFP during liver development.

  2. Findings indicate that AFP expressed under experimental cryptorchid conditions plays a role as a regulatory factor in spermatogenesis and in hepatic generation.

  3. AFP mRNA and VEGF-C (显示 VEGFC 蛋白) mRNA in peripheral blood were significantly correlated with recurrence and metastasis of hepatocellular carcinoma.

  4. A DEHP treatment-induced phenotype was identified with lack of glycogen (显示 GYS1 蛋白) accumula-tion and intracytoplasmic localization of beta-catenin (显示 CTNNB1 蛋白) which was associated with increased AFP gene expression.

  5. The deficits observed in parental behavior of AFP knockout females could not be explained by any changes in olfactory function, novelty recognition or anxiety

  6. Foxa1 (显示 FOXA1 蛋白) acts as a pioneer transcription factor in de novo activation of Afp, by exploiting a lack of methylation at juxtaposed transposed elements

  7. The level of AFP mRNA in peripheral blood may indicate recurrence and/or metastasis after curative resection of hepatocellular carcinoma.

  8. AFP affects cell proliferation by binding its receptor to trigger the signal transduction pathway of cAMP-PKA and alter the expression of K- ras (显示 HRAS 蛋白) p21 genes

  9. A murine Nkx2.8 (显示 NKX2-6 蛋白) was isolated from the Hepal-6 cell line and showed oligonucleotide binding competitive with fetoprotein transcription factor (显示 NR5A2 蛋白).

  10. The mouse alpha-fetoprotein promoter is repressed in HepG2 hepatoma cells by hepatocyte nuclear factor-3 (显示 FOXA1 蛋白)

Human alpha-Fetoprotein (AFP) interaction partners

  1. We could demonstrate in our cohort the superior detection of early stage HCC (显示 FAM126A 蛋白) with the combined use of the respective biomarkers and in particular GALAD even in AFP-negative tumors.

  2. A correlation was found between serum AFP concentration and age in extremely low-birthweight infants (ELBWI), and the 95%CI of serum AFP concentration was determined for ELBWI up to 2 years after birth.

  3. rAFP promoted growth of the human HCC (显示 FAM126A 蛋白) cells, antagonize paclitaxel inhibition of HCC (显示 FAM126A 蛋白) cell proliferation, suppress expression of active caspase-3 (显示 CASP3 蛋白), and promote expression of Ras and survivin (显示 BIRC5 蛋白).

  4. Measurements of serum alpha-fetoprotein (AFP) levels could be helpful in detecting progression or recurrence in treated patients with hepatitis B virus (HBV) - hepatocellular carcinoma (HCC (显示 FAM126A 蛋白)) and normal alanine aminotransferase (显示 ALT 蛋白) (ALT).

  5. AFP mRNA level is in enriched circulating tumor cells from patients with metastatic hepatocellular carcinoma.

  6. High serum AFP levels were significantly associated with the prevalence of metabolic syndrome in a Chinese asymptomatic population.

  7. Contrary to expectation, Chronic Hepatitis B patients with current or recent exposure to NA therapy showed poorer performance of AFP during hepatocellular carcinoma surveillance

  8. Protein induced by vitamin K absence or antagonist-II showed higher area under the curve than alpha-fetoprotein for diagnosis of hepatitis B virus-related hepatocellular carcinoma patients (0.901 vs 0.788).We conclude that Combining alpha-fetoprotein and protein induced by vitamin K absence or antagonist-II may improve the diagnostic value for early detection of hepatocellular carcinoma.

  9. AFP expression turned on prior to expression of Oct4 (显示 POU5F1 蛋白), Klf4 (显示 KLF4 蛋白), Sox2 (显示 SOX2 蛋白) and c-myc (显示 MYC 蛋白), and the stemness markers CD44 (显示 CD44 蛋白), CD133 and EpCAM (显示 EPCAM 蛋白) in the normal human liver L-02 cell line or CHL (显示 CHRDL1 蛋白) cell lines upon transfection with MCV-HBx vectors. HBx stimulates AFP expression to induce natural reprogramming of liver cells, and AFP plays a critical role in promoting the initiation of HCC (显示 FAM126A 蛋白) progenitor/stem cells.

  10. analysis of alpha-fetoprotein producing early gastric cancer with enteroblastic differentiation

Horse (Equine) alpha-Fetoprotein (AFP) interaction partners

  1. Equine alpha-fetoprotein seems to be an important indicator of fetal well-being in horses.

  2. This study confirmed that alpha-fetoprotein (AFP) is present in the fetal fluids of mares during the third trimester of pregnancy; experimentally induced placentitis was associated with an elevation in maternal plasma concentrations of AFP.

蛋白简介alpha Fetoprotein (AFP)


This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Alternative names and synonyms associated with alpha Fetoprotein (AFP)

  • alpha-fetoprotein (AFP)
  • alpha fetoprotein (Afp)
  • alpha-fetoprotein (Afp)
  • FETA 蛋白
  • HPAFP 蛋白

Protein level used designations for alpha-Fetoprotein 蛋白 (AFP)

alpha-1-fetoprotein , alpha-fetoglobulin , alpha-fetoprotein , alpha-foetoprotein , chloride intracellular channel 6

704786 Macaca mulatta
11576 Mus musculus
174 Homo sapiens
403551 Canis lupus familiaris
397586 Sus scrofa
24177 Rattus norvegicus
506011 Bos taurus
422652 Gallus gallus
100034185 Equus caballus
100345865 Oryctolagus cuniculus
100728693 Cavia porcellus
461258 Pan troglodytes
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