MAL 蛋白 (MAL)产品概述

Full name:
Myelin and Lymphocyte Protein, T Cell Differentiation Protein 蛋白 (MAL)
在www.antibodies-online.cn可供6 Myelin and Lymphocyte Protein, T Cell Differentiation Protein (MAL) 蛋白的3不同的供货商。 再加上,我们可以发MAL 抗体 (61)MAL 试剂盒 (5)和数多这个蛋白质的别的产品。 总共74 MAL产品已列进来了。
mal, MALGENE, Mpv17, Vip17
列出全部蛋白 基因 基因ID UniProt
MAL 4118 P21145
MAL 17153 O09198
大鼠 MAL MAL 25263 Q64349


按照种类MAL 蛋白 (MAL)



Human Myelin and Lymphocyte Protein, T Cell Differentiation Protein (MAL) interaction partners

  1. Here the authors show that MAL TIR domains spontaneously and reversibly form filaments in vitro. They also form cofilaments with TLR4 (显示 TLR4 蛋白) TIR domains and induce formation of MyD88 (显示 MYD88 蛋白) assemblies.

  2. MAL and TMEM220 were specifically methylated and were down-regulated in human gastric cancer.

  3. Results show that MAl protein (显示 Mall 蛋白) binds to and regulates MYD88 (显示 MYD88 蛋白).

  4. This study revealed that Merkel cell polyomavirus -negative Merkel cell carcinomas significantly expressed higher CADM1 and lower MAL than Merkel cell polyomavirus -positive Merkel cell carcinomas

  5. CADM1/MAL methylation increases with severity of cervical intraepithelial neoplasia

  6. Hypermethylation of the selected markers (MAL, PRIMA1 (显示 PRIMA1 蛋白), PTGDR (显示 PTGDR 蛋白) and SFRP1 (显示 SFRP1 蛋白)) can result in reduced gene expression and may contribute to the formation of colorectal cancer.

  7. Data suggest that expression of MAL in cells confers both ETX (Clostridium perfringens epsilon-toxin) binding and susceptibility to ETX-mediated cell death; cells expressing rat MAL are 100 times more sensitive to ETX than cells expressing human MAL.

  8. The use of CADM1, MAL, and MIR124-2 as biomarkers for full molecular screening in HIV infected women who are also positive for human papillomavirus.

  9. MAL is a critical element of the machinery for exosome secretion and may constitute a target for modulating exosome secretion by human T cells.

  10. MAL hypermethylation is associated with esophageal carcinoma progression.

Mouse (Murine) Myelin and Lymphocyte Protein, T Cell Differentiation Protein (MAL) interaction partners

  1. Expression of the developmentally regulated proteolipid MAL is required for the cytotoxic effect of Clostridium perfringens Epsilon Toxin.

  2. MAL (显示 TIRAP 蛋白) overexpression leads to reduced expression of Mpz and p75NTR (显示 NGFR 蛋白), despite functional pathways and normal expression of genes important for Schwann cell differentiation.

  3. the exclusion of MAL from the expanding 2D crystals of uroplakins explains the selective association of MAL with the hinge areas in the uroplakin-delivering fusiform vesicles, as well as at the apical surface

  4. Phagosomal retention of Francisella tularensis results in TIRAP/Mal (显示 TIRAP 蛋白)-independent TLR2 signaling.

  5. The specific reduction and mistargeting of MAL protein (显示 Mall 蛋白) as a reaction to sulfatide overload may contribute to the pathogenic mechanisms in metachromatic leukodystrophy.

  6. Our results demonstrate a critical role for MAL in the maintenance of central nervous system paranodes, likely by controlling the trafficking and/or sorting of NF155 and other membrane components in oligodendrocytes.

  7. Our results suggest a functional role for MAL in peripheral myelination by influencing the expression of membrane components that mediate axon-glia interaction during ensheathment and myelin wrapping.

Cow (Bovine) Myelin and Lymphocyte Protein, T Cell Differentiation Protein (MAL) interaction partners

  1. SYP is an hexameric MAL-domain channel protein.



The protein encoded by this gene is a highly hydrophobic integral membrane protein belonging to the MAL family of proteolipids. The protein has been localized to the endoplasmic reticulum of T-cells and is a candidate linker protein in T-cell signal transduction. In addition, this proteolipid is localized in compact myelin of cells in the nervous system and has been implicated in myelin biogenesis and/or function. The protein plays a role in the formation, stabilization and maintenance of glycosphingolipid-enriched membrane microdomains. Down-regulation of this gene has been associated with a variety of human epithelial malignancies. Alternative splicing produces four transcript variants which vary from each other by the presence or absence of alternatively spliced exons 2 and 3.

Alternative names and synonyms associated with MAL

  • mal, T-cell differentiation protein (MAL)
  • myelin and lymphocyte protein, T cell differentiation protein (Mal)
  • myelin and lymphocyte protein (mal)
  • Myelin and lymphocyte protein (mal)
  • mal, T-cell differentiation protein (Mal)
  • mal 蛋白
  • MALGENE 蛋白
  • Mpv17 蛋白
  • Vip17 蛋白

Protein level used designations for MAL

T-lymphocyte maturation-associated protein , myelin and lymphocyte protein , myelin and lymphocyte protein, T-cell differentiation protein , Myelin and lymphocyte protein , 17 kDa myelin vesicular protein , MVP17 , NS 3 , VIP17 proteolipid , VIP17/MAL proteolipid

4118 Homo sapiens
17153 Mus musculus
510077 Bos taurus
100135389 Xenopus (Silurana) tropicalis
100196291 Salmo salar
25263 Rattus norvegicus
403933 Canis lupus familiaris
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