TIMP Metallopeptidase Inhibitor 1 (TIMP1) ELISA试剂盒

TIMP1 belongs to the TIMP gene family. 再加上,我们可以发TIMP1 抗体 (306)TIMP1 蛋白 (61)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
TIMP1 7076 P01033
TIMP1 116510 P30120
TIMP1 21857 P12032

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0.434 ng/mL 0.39-25 ng/mL 96 Tests Log in to see 7至10个工作日
¥3,994.38
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大鼠 0.063 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 7至10个工作日
¥1,771.61
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小鼠 0.059 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 7至10个工作日
¥2,354.27
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13.2 pg/mL 31.2-2000 pg/mL 96 Tests Log in to see 7至10个工作日
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37 pg/mL 78.125-5000 pg/mL   96 Tests Log in to see 9至11个工作日
¥4,293.90
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大鼠 0.055 ng/mL 0.156-10 ng/mL 96 Tests Log in to see 9至11个工作日
¥4,527.90
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0.119 ng/mL 0.312-20 ng/mL 96 Tests Log in to see 9至11个工作日
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0.066 ng/mL 0.156-10 ng/mL 96 Tests Log in to see 9至11个工作日
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24.5 pg/mL 62.50-4000 pg/mL 96 Tests Log in to see 7至10个工作日
¥3,403.06
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0.241 ng/mL 0.62-40 ng/mL 96 Tests Log in to see 7至10个工作日
¥3,840.06
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引用最多的TIMP1 ELISA试剂盒

  1. Mouse (Murine) TIMP1 ELISA Kit for Sandwich ELISA - ABIN424239 : Lenglet, Montecucco, Mach, Schaller, Gasche, Copin: Analysis of the expression of nine secreted matrix metalloproteinases and their endogenous inhibitors in the brain of mice subjected to ischaemic stroke. in Thrombosis and haemostasis 2014 (PubMed)
    Show all 5 references for 424239

  2. Rat (Rattus) TIMP1 ELISA Kit for Sandwich ELISA - ABIN416390 : Michalski, Pelz, Weise, Kacza, Boltze, Grosche, Kamprad, Schneider, Hobohm, Härtig: Early outcome and blood-brain barrier integrity after co-administered thrombolysis and hyperbaric oxygenation in experimental stroke. in Experimental & translational stroke medicine 2011 (PubMed)
    Show all 3 references for 416390

  3. Dog (Canine) TIMP1 ELISA Kit for Sandwich ELISA - ABIN572396 : Kuraoka, Kimura, Nagata, Okada, Aoki, Tachimori, Yonemoto, Imamura, Takeda: Serum Osteopontin as a Novel Biomarker for Muscle Regeneration in Duchenne Muscular Dystrophy. in The American journal of pathology 2016 (PubMed)
    Show all 2 references for 572396

  4. Human TIMP1 ELISA Kit for Sandwich ELISA - ABIN365420 : Leppilahti, Hernández-Ríos, Gamonal, Tervahartiala, Brignardello-Petersen, Mantyla, Sorsa, Hernández: Matrix metalloproteinases and myeloperoxidase in gingival crevicular fluid provide site-specific diagnostic value for chronic periodontitis. in Journal of clinical periodontology 2014 (PubMed)

适于 TIMP1 相互作用对的更多 ELISA 试剂盒

Human TIMP Metallopeptidase Inhibitor 1 (TIMP1) interaction partners

  1. This study indicates that in our population, the COL4A3 (显示 COL4a3 ELISA试剂盒) rs55703767 polymorphism decreased the risk of KC. However, the TIMP-1 rs6609533 polymorphism was associated with an increased risk of KC.

  2. Low MMP-8 (显示 MMP8 ELISA试剂盒)/TIMP-1 reflects left ventricle impairment in takotsubo cardiomyopathy and high TIMP-1 may help to differentiate it from acute coronary syndrome

  3. Data show that the mean values for TIMP1, TIMP2 (显示 TIMP2 ELISA试剂盒) and MMP2 (显示 MMP2 ELISA试剂盒) were lower in survivors, MMP9 (显示 MMP9 ELISA试剂盒) was higher in survivors.

  4. We conclude that in the resected esophageal cancer an increased mRNA expression of MMP-7 (显示 MMP7 ELISA试剂盒), MMP-10 (显示 MMP10 ELISA试剂盒) and TIMP-1 correlated with clinicopathologic features. We suggest that these genes may play a role during progression of the diseaseMMP-10, MMP-7 (显示 MMP7 ELISA试剂盒), TIMP-1, TIMP-2 (显示 TIMP2 ELISA试剂盒) were overexpressed in 73%, 85%, 55% and 42% of esophageal cancer samples, respectively.

  5. plasma concentrations of MMP-7 (显示 MMP7 ELISA试剂盒), MMP-8 (显示 MMP8 ELISA试剂盒), -9 and TIMP-1 within 96 h from the onset of acute pancreatitis symptoms are elevated in acute pancreatitis patients compared with healthy controls

  6. High TIMP1 expression is associated with hepatic fibrosis.

  7. TIMP-1 was highly expressed in TNBC patients and was associated with a poor prognosis.

  8. Results suggest a crucial role of MMP9 (显示 MMP9 ELISA试剂盒) at the early stage of carcinogenesis in the large intestine. The increase in MMP9 (显示 MMP9 ELISA试剂盒) and TIMP1 mRNA concentration and the decrease in MMP28 (显示 MMP28 ELISA试剂盒) in the large intestinal tissue may be a confirmation of cancer.

  9. Expression of TIMP1 is i (显示 CD63 ELISA试剂盒)ncreased in chronic pancreatitis, pancreatic intra-epithelial neoplasia, and pancreatic ductal adenocarcinoma tissues from patients. TIMP1 signaling via CD63 leads to activation of hepatic stellate cells, which create an environment in the liver that increases its susceptibility to pancreatic tumor cells.

  10. Our study provides information on the dynamic changes of MMP-9 (显示 MMP9 ELISA试剂盒)-TIMP-1 system and S100B (显示 S100B ELISA试剂盒) in the perioperative period. Preoperative reduction of TIMP-1 might be predictive for shunt requirement but future studies are required for verification.

Cow (Bovine) TIMP Metallopeptidase Inhibitor 1 (TIMP1) interaction partners

  1. Decreased MMP-9 (显示 MMP9 ELISA试剂盒) and increased TIMP-1 expression were found in peripheral blood cells from Mycobacterium avium subsp. paratuberculosis (Map)-infected cattle after stimulation with Map lysate and Map purified protein derivative than in control cattle.

  2. We used a trophoblast cell line (F3) derived from bovine placentomes to examine the influence of EGF (显示 EGF ELISA试剂盒) on MMP-9 (显示 MMP9 ELISA试剂盒) and TIMP-1 expression by semiquantitative RT-PCR and MMP activity by zymography.

  3. Production of TIMP-1 was augmented by IL-1alpha, TNFalpha (显示 TNF ELISA试剂盒), and hepatocyte growth factor (显示 HGF ELISA试剂盒) at level of translation and was transcriptionally increased by 12-O-tetradecanoylphorbol 13-acetate. Level of TIMP-2 (显示 TIMP2 ELISA试剂盒) mRNA was not affected by any treatments.

  4. the different temporal expression patterns of TIMP-1 and TIMP-2 (显示 TIMP2 ELISA试剂盒) suggest that TIMP-1 may be important for luteal formation and development, while TIMP-2 (显示 TIMP2 ELISA试剂盒) may play significant roles during luteal development and maintenance

  5. analysis of species specificity of human and bovine TIMP-1 binding to mouse TIMP-1 receptor

Pig (Porcine) TIMP Metallopeptidase Inhibitor 1 (TIMP1) interaction partners

  1. we demonstrated the presence of high molecular weight (HMW) complexes (130, 170, and 220 kDa) containing MMP9 (显示 MMP9 ELISA试剂盒), TIMP1, and NGAL (显示 LCN2 ELISA试剂盒) (also MMP2 (显示 MMP2 ELISA试剂盒) in 220 kDa complex) without proteolytic activity.

  2. Hemodialysis graft placement leads to early increases in wall shear stress, VEGF-A (显示 VEGFA ELISA试剂盒), pro-MMP-9 (显示 MMP9 ELISA试剂盒), MMP-2 (显示 MMP2 ELISA试剂盒), VEGFR-1 (显示 FLT1 ELISA试剂盒), VEGFR-2 (显示 KDR ELISA试剂盒), and TIMP-1, which may contribute to the development of venous stenosis.

  3. Results indicate that leukemia inhibitory factor (LIF (显示 LIF ELISA试剂盒)) and Oncostatin M (显示 OSM ELISA试剂盒) increase the expression of MMP-1 (显示 MMP1 ELISA试剂盒), MMP-3 (显示 MMP3 ELISA试剂盒), and TIMP-1 several fold, and that their expression is reduced to basal levels in the presence of the LIF (显示 LIF ELISA试剂盒) antagonist MH35-BD.

Rabbit TIMP Metallopeptidase Inhibitor 1 (TIMP1) interaction partners

  1. Hemoperfusion could obviously reduce oxidative stress and the expression levels of MMP-2 (显示 MMP2 ELISA试剂盒), MMP-9 (显示 MMP9 ELISA试剂盒) and TIMP-1 in rabbits with acute paraquat poisoning.

Mouse (Murine) TIMP Metallopeptidase Inhibitor 1 (TIMP1) interaction partners

  1. proteomic analysis of the mesenchymal stem cells secretome identified the TIMP-1 as a potential effector molecule responsible for the anti-angiogenic properties of MSC (显示 MSC ELISA试剂盒)

  2. TIMP1 signaling via CD63 (显示 CD63 ELISA试剂盒) leads to activation of hepatic stellate cells, which create an environment in the liver that increases its susceptibility to pancreatic tumor cells.

  3. This study highlights a previously undescribed integral role for TIMP1 in both vascular network maturation and adaptations to ischemia or alterations in flow.

  4. TIMP-1 was identified as a selectively upregulated component secreted from immature astrocytes from human pluripotent stem cells.

  5. demonstrate that TIMP-2 (显示 TIMP2 ELISA试剂盒) plays a greater protective role than TIMP-1 during the pathogenesis of atherosclerosis

  6. Our findings reveal that elevated levels of TIMP-1 impact on neutrophil homeostasis via signaling through CD63 (显示 CD63 ELISA试剂盒).

  7. TIMP-1 is a ligand of LRP-1 (显示 LRP1 ELISA试剂盒) and we highlight a new example of its MMP-independent, cytokine-like functions.

  8. RAB37 (显示 RAB37 ELISA试剂盒) regulates the exocytosis of TIMP1 in a nucleotide-dependent manner to inactivate MMP9 (显示 MMP9 ELISA试剂盒) migration axis in vitro and in vivo and to suppress tumor metastasis.

  9. PDGF-D (显示 PDGFD ELISA试剂盒) intensifies fibrogenesis by interfering with the fibrolytic activity of the TIMP-1/MMP-2 (显示 MMP2 ELISA试剂盒)/MMP (显示 MMP2 ELISA试剂盒)-9 (显示 MMP9 ELISA试剂盒) system, and PDGF-D (显示 PDGFD ELISA试剂盒) signaling is mediated through both PDGF (显示 PDGFA ELISA试剂盒)-alpha and -beta receptors.

  10. Reduced beta(2)GP I plays a role in diabetic mice related to vascular protection, inhibiting vascular lipid deposition, and plaque formation by reducing MMPs/TIMPs expression through down-regulation of the p38MAPK (显示 MAPK14 ELISA试剂盒) signaling pathway.

TIMP1 抗原简介

Antigen Summary

This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.

Gene names and symbols associated with TIMP1

  • TIMP metallopeptidase inhibitor 1 (TIMP1) 抗体
  • TIMP metallopeptidase inhibitor 1 (Timp1) 抗体
  • tissue inhibitor of metalloproteinase 1 (LOC100009047) 抗体
  • tissue inhibitor of metalloproteinase 1 (Timp1) 抗体
  • Clgi 抗体
  • DKFZp468A0912 抗体
  • EPA 抗体
  • EPO 抗体
  • HCI 抗体
  • Timp 抗体
  • TIMP-1 抗体
  • TIMP1 抗体

Protein level used designations for TIMP1

tissue inhibitor of matrix metalloproteinase-1 , TIMP metallopeptidase inhibitor 1 , Metalloproteinase inhibitor 1 , TIMP-1 , collagenase inhibitor , erythroid potentiating activity , erythroid-potentiating activity , fibroblast collagenase inhibitor , metalloproteinase inhibitor 1 , tissue inhibitor of metalloproteinases 1 , EG-1 , embryogenin-1 , tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor) , tissue inhibitor of metallopeptidase 1 , tissue inhibitor of metalloproteinase 1 , metalloproteinase tissue inhibitor , metalloproteinase tissue inhibitor 1 , EPA , TPA-S1 , TPA-induced protein , collagenase inhibitor 16C8 fibroblast , tissue inhibitor of metalloproteinase-1

GENE ID SPECIES
574348 Macaca mulatta
100172253 Pongo abelii
7076 Homo sapiens
282092 Bos taurus
116510 Rattus norvegicus
101686851 Mustela putorius furo
443331 Ovis aries
396862 Sus scrofa
403816 Canis lupus familiaris
100009047 Oryctolagus cuniculus
21857 Mus musculus
100034220 Equus caballus
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