PHD Finger Protein 8 (PHF8) ELISA试剂盒

The protein encoded by PHF8 is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. 再加上,我们可以发PHF8 抗体 (34)PHF8 蛋白 (4)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
 PHF8 PHF8 23133 Q9UPP1
大鼠 PHF8 PHF8 317425  
PHF8 320595 Q80TJ7

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小鼠 0.118 ng/mL 0.312-20 ng/mL 96 Tests Log in to see 9至11个工作日
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适于 PHF8 相互作用对的更多 ELISA 试剂盒

Human PHD Finger Protein 8 (PHF8) interaction partners

  1. USP7 (显示 USP7 ELISA试剂盒) promotes breast carcinogenesis by stabilizing PHF8 and upregulating cyclin A2 (显示 CCNA2 ELISA试剂盒). and the interaction between USP7 (显示 USP7 ELISA试剂盒) and PHF8 is augmented during DNA damage.

  2. PHF8 reduces the H3K9me2 level at the E2F4 (显示 E2F4 ELISA试剂盒) transcriptional start site, demonstrating a direct function of PHF8 in endothelial E2F4 (显示 E2F4 ELISA试剂盒) gene regulation

  3. PHF2 (显示 PHF1 ELISA试剂盒) is likely to repress rDNA transcription by competing with PHF8 for binding of ribosomal DNA promoter and by recruiting H3K9me2/3 methyltransferase SUV39H1 (显示 SUV39H1 ELISA试剂盒).

  4. PHF8 promotes lung cancer cell growth and survival by regulating miR (显示 MLXIP ELISA试剂盒)-21.

  5. knockdown of PHF8 led to a reduction in the number of migratory and invasive cells. Furthermore, downregulation of PHF8 attenuated the tumorigenicity of ESCC cells in vivo.

  6. PHF8 is regulated by APC (显示 APC ELISA试剂盒)(cdc20 (显示 CDC20 ELISA试剂盒)) and plays an important role in the G2/M transition.

  7. study identified the histone demethylase (显示 MBD2 ELISA试剂盒) PHF8 as a coactivator that is specifically recruited by RAR-alpha (显示 RARA ELISA试剂盒) fusions to activate expression of their downstream targets upon all-trans retinoic acid treatment in acute promyelocytic leukemia (显示 PML ELISA试剂盒)

  8. Results show that PHF8 controls the expression of genes involved in cell adhesion and cytoskeleton organization such as RhoA (显示 RHOA ELISA试剂盒), Rac1 and GSK3beta (显示 GSK3b ELISA试剂盒).

  9. a role of PHF8 in cell migration and invasion

  10. PHF8 is a histone demethylase and coactivator for RARalpha and that the F279S mutation identified in an XLMR patient results in loss of its demethylase activity.

Mouse (Murine) PHD Finger Protein 8 (PHF8) interaction partners

  1. PHF8 overexpression reversed cardiac dysfunction, hypertrophy and fibrosis upon pressure overload in PHF8 transgenic mice.

  2. The gene knockdown of PHF8 in mouse embryonic carcinoma P19 cells impairs RA-induced neuronal differentiation.

  3. an important function of PHF8 is in midline formation and in the development of cognitive abilities, and may have a role in X linked mental retardation associated with cleft lip/palate

Zebrafish PHD Finger Protein 8 (PHF8) interaction partners

  1. PHF8 regulates zebrafish neuronal cell survival and jaw development in part by directly regulating the expression of the homeodomain transcription factor MSX1/MSXB, which functions downstream of multiple signalling and developmental pathways

PHF8 抗原简介

Antigen Summary

The protein encoded by this gene is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. The encoded protein requires Fe(2+) ion, 2-oxoglutarate, and oxygen for its catalytic activity. Defects in this gene are a cause of mental retardation syndromic X-linked Siderius type (MRXSSD). Four transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with PHF8

  • PHD finger protein 8 (PHF8) 抗体
  • PHD finger protein 8 (Phf8) 抗体
  • PHD finger protein 8 (phf8) 抗体
  • RIKEN cDNA 4921501E09 gene (4921501E09Rik) 抗体
  • 9830141C09Rik 抗体
  • JHDM1F 抗体
  • mKIAA1111 抗体
  • MRXSSD 抗体
  • PHF8 抗体
  • RGD1561065 抗体
  • ZNF422 抗体
  • zPHF8 抗体

Protein level used designations for PHF8

histone lysine demethylase PHF8 , jumonji C domain-containing histone demethylase 1F , KIAA1111-like protein , PHD finger protein 8-like

GENE ID SPECIES
23133 Homo sapiens
491897 Canis lupus familiaris
100520413 Sus scrofa
513959 Bos taurus
317425 Rattus norvegicus
320595 Mus musculus
566534 Danio rerio
74042 Mus musculus
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