anti-Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR) 抗体

M6PR encodes a member of the P-type lectin family. 再加上,我们可以发M6PR 蛋白 (10)M6PR 试剂盒 (8)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
M6PR 16004 Q07113
M6PR 4074 P20645
M6PR 312689 Q6AY20
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Showing 10 out of 71 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB <b>WB Suggested Anti-M6PR Antibody Titration: </b>5.0ug/ml<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Log in to see 2至3个工作日
非结合性 FACS, IF, WB M6PR Antibody (C-term) (ABIN650726) western blot analysis in A549 cell line lysates (35 µg/lane).This demonstrates the M6PR antibody detected the M6PR protein (arrow). M6PR Antibody (C-term) (ABIN650726) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. 400 μL Log in to see 10至11个工作日
非结合性 EIA, IHC (p) 0.4 mL Log in to see 6至8个工作日
山羊 非结合性 ELISA, WB   100 μg Log in to see 6至7个工作日
非结合性 IHC (p), WB Western blot analysis of M6PR Antibody (N-term)(ABIN389291) in mouse brain tissue lysates (35 µg/lane). M6PR (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human testis tissue reacted with M6PR antibody (N-term) (ABIN389291), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10至11个工作日
Cow 山羊 非结合性 ELISA   0.1 mg Log in to see 7至9个工作日
小鼠 非结合性 IHC, WB WB on rat brain lysate using Rabbit antibody to internal region of MPRD (Cation dependent mannose-6-phosphate receptor): whole serum (ABIN350471) at 1 : 1000 dilution. Pre-absorption of the antibody with the immunising peptide completely abolishes the detected band. 100 μL Log in to see 7至8个工作日
小鼠 非结合性 ELISA, WB Western Blot detection against Immunogen (33.48 KDa) . 50 μL Log in to see 11至12个工作日
非结合性 WB 100 μg Log in to see 7至9个工作日
Bat 山羊 非结合性 ELISA   100 μg Log in to see 7至9个工作日

通过反应活性、应用领域、克隆类型和共轭标记 M6PR 抗体

特性 应用范围 宿主 克隆类型 标记
Mouse (Murine) , ,
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Human , , , ,
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Rat (Rattus) , ,
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引用最多的anti-M6PR 抗体

  1. Human Polyclonal M6PR Primary Antibody for ELISA, WB - ABIN561704 : Steffan, Williams, Welbourne, Cardelli: HGF-induced invasion by prostate tumor cells requires anterograde lysosome trafficking and activity of Na+-H+ exchangers. in Journal of cell science 2010 (PubMed)
    Show all 2 Pubmed References

  2. Cow (Bovine) Polyclonal M6PR Primary Antibody for ELISA - ABIN408673 : Frei, Jeon, Kilcher, Moest, Henning, Jost, Plückthun, Mercer, Aebersold, Carreira, Wollscheid: Direct identification of ligand-receptor interactions on living cells and tissues. in Nature biotechnology 2012 (PubMed)
    Show all 2 Pubmed References


Zebrafish Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR) interaction partners

  1. Analysis of full-length sequences for MPR 46 from zebrafish (Danio rerio) and its functional analysis.

Rhesus Monkey Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR) interaction partners

  1. Rotaviruses reach late endosomes and require M6PR and cathepsin proteases to enter the cell.

Mouse (Murine) Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR) interaction partners

  1. Selective M6PR down-regulation has a critical role in CD8 (显示 CD8A 抗体)(+) T cell survival.

  2. Expression of imprinted gene Igf2r (显示 IGF2R 抗体) was unregulated in haploid androgenetic/gynogenetic blastocysts.

  3. that an elevation in IGF-II receptor (显示 IGF2R 抗体) levels can influence the expression profiles of transcripts as well as proteins that are involved in AD pathogenesis.

  4. DNA methylation (显示 HELLS 抗体) changes were noted in the Igf2r (显示 IGF2R 抗体) gene during chronic cystitis in a murine model.

  5. Airn expression is both necessary and sufficient to silence Igf2r (显示 IGF2R 抗体) throughout embryonic stem cell differentiation.

  6. We conclude that M6PR is an important receptor used by HIV-1 to cross the blood-brain barrier.

  7. The results excluded a role for spliced and unspliced Airn lncRNA products and for Airn nuclear size and location in silencing Igf2r. Instead, silencing only required Airn transcriptional overlap of the Igf2r promoter, which interferes with RNA polymerase II recruitment in the absence of repressive chromatin.

  8. mannose 6-phosphate/IGF2R knock-down in receptor-positive mouse hepatocytes causes increased cathepsin secretion as well as enhanced cell motility and invasiveness

  9. enhanced CI-MPR (显示 IGF2R 抗体) expression might improve the efficacy of enzyme replacement therapy in Pompe disease through enhancing receptor-mediated uptake of GAA (显示 GAA 抗体).

  10. The interaction of sM6P/IGF2R (显示 IGF2R 抗体) with Plg (显示 PLG 抗体) may be an important regulatory mechanism to inhibit migration of cells using the uPA (显示 PLAU 抗体)/uPAR (显示 PLAUR 抗体) system.

Human Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR) interaction partners

  1. In light of existing report suggesting critical role of Nef-GCC185 (显示 GCC2 抗体) interaction reveals valuable mechanistic insights affecting specific protein transport pathway in docking of late endosome derived Rab9 (显示 RAB9A 抗体) bearing transport vesicle at TGN (显示 TG 抗体) elucidating role of Nef during viral pathogenesis.

  2. Results suggest that Rab (显示 HRB 抗体) protein Rab29 (显示 RAB7L1 抗体) is essential for the integrity of the trans-Golgi network (TGN (显示 TG 抗体)) and participates in the retrograde trafficking of mannose-6-phosphate receptor (M6PR).

  3. These data indicate that clathrin is required for the function of AP-1 (显示 FOSB 抗体)- and GGA-coated carriers at the trans-Golgi network but may be dispensable for outward traffic en route to the plasma membrane.

  4. Sortilin (显示 SORT1 抗体) is a new alpha-Gal A receptor expressed in renal endothelial cells and that this receptor together with the M6PR (显示 IGF2R 抗体) is able to internalize circulating alpha-Gal A.

  5. Mannose receptor (MR) engagement by mesothelin (显示 MSLN 抗体) GPI (显示 GNPDA1 抗体) anchor polarizes tumor-associated macrophages and is blocked by anti-MR human recombinant antibody

  6. sorting of the CD-MPR in late endosomes requires a distinct di-aromatic motif with only limited possibilities for variations

  7. We conclude that the CI-MPR (显示 IGF2R 抗体) participates in lysosomal and granular targeting of serglycin (显示 SRGN 抗体) and basic proteins such as lysozyme (显示 LYZ 抗体) associated with the proteoglycan (显示 Vcan 抗体) in hematopoietic cells.

  8. sortilin (显示 SORT1 抗体) and mannose-6-phosphate receptors recycle to the TGN (显示 TG 抗体) in SNX1 (显示 SNX1 抗体)-dependent carriers, which we named endosome-to-TGN (显示 TG 抗体) transport carriers

  9. Missorting of cathepsin D (显示 CTSD 抗体) in GARP (显示 CNGB1 抗体)-depleted cells results from accumulation of recycling MPRs in a population of light, small vesicles downstream of endosomes.

  10. Data demonstrate that Rab31 (显示 RAB31 抗体) is required for transport of mannose 6-phosphate receptors from the trans-Golgi network to endosomes and for the Golgi/TGN (显示 TG 抗体) organization.

Cow (Bovine) Mannose-6-Phosphate Receptor (Cation Dependent) (M6PR) interaction partners

  1. Rotaviruses reach late endosomes and require M6PR and cathepsin proteases to enter the cell.

  2. Expression and binding properties of mannose-6-phosphate receptors CD-MPR and CI-MPR (显示 IGF2R 抗体) differ during perinatal development in rat liver.

M6PR 抗原简介


This gene encodes a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X.

Gene names and symbols associated with M6PR

  • mannose-6-phosphate receptor (cation dependent) L homeolog (m6pr.L) 抗体
  • mannose-6-phosphate receptor, cation dependent (M6PR) 抗体
  • mannose-6-phosphate receptor (cation dependent) (m6pr) 抗体
  • mannose-6-phosphate receptor (cation dependent) S homeolog (m6pr.S) 抗体
  • mannose-6-phosphate receptor (cation dependent) (Ethha_1678) 抗体
  • Cation-dependent mannose-6-phosphate receptor (mprd) 抗体
  • insulin-like growth factor 2 receptor (Igf2r) 抗体
  • mannose-6-phosphate receptor, cation dependent (M6pr) 抗体
  • AI661837 抗体
  • CD-MPR 抗体
  • CD222 抗体
  • CDMPR 抗体
  • CI-MPR 抗体
  • M6P/IGF2R 抗体
  • M6PR 抗体
  • MGC68896 抗体
  • MGC89423 抗体
  • MGC130765 抗体
  • MPR-46 抗体
  • MPR 46 抗体
  • Mpr46 抗体
  • Mpr300 抗体
  • mprd 抗体
  • SMPR 抗体
  • wu:fj81h11 抗体
  • zgc:77757 抗体

Protein level used designations for M6PR

mannose-6-phosphate receptor (cation dependent) , Mannose 6-Phosphate Receptor , cation-dependent mannose-6-phosphate receptor , CD-MPR , Cation-dependent mannose-6-phosphate receptor , 300 kDa mannose 6-phosphate receptor , CI Man-6-P receptor , IGF-II receptor , IGF-II/CI-MPR , M6P/IGF2 receptor , M6PR , MPR 300 , cation-independent MPR , cation-independent mannose 6-phosphate receptor , cation-independent mannose-6-phosphate receptor , insulin-like growth factor II receptor , mannose-6-phosphate receptor, cation independent , 46-kDa mannose 6-phosphate receptor , CD Man-6-P receptor , Mr 46,000 Man6PR , small mannose 6-phosphate receptor , 46 kDa mannose 6-phosphate receptor , MPR 46

380564 Xenopus laevis
396044 Gallus gallus
406486 Danio rerio
493477 Xenopus (Silurana) tropicalis
496207 Xenopus laevis
716696 Macaca mulatta
736013 Pan troglodytes
10092655 Ethanoligenens harbinense YUAN-3
100194796 Salmo salar
16004 Mus musculus
4074 Homo sapiens
477700 Canis lupus familiaris
281291 Bos taurus
312689 Rattus norvegicus
17113 Mus musculus
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