anti-Malic Enzyme Complex, Mitochondrial (Mod2) 抗体

The membrane-associated protein encoded by Mod2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. 再加上,我们可以发Malic Enzyme Complex, Mitochondrial 蛋白 (2)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
小鼠 Mod2 Mod2 110357  
Mod2 5243 P08183
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通过反应活性、应用领域、克隆类型和共轭标记 Mod2 抗体

特性 应用范围 宿主 克隆类型 标记
Human , ,


,

更多抗Malic Enzyme Complex, Mitochondrial的相互作用对抗体

Human Malic Enzyme Complex, Mitochondrial (Mod2) interaction partners

  1. Compared with the sensitive group, both mdr1 (显示 TBC1D9 抗体) mRNA and P-gp (显示 ABCB4 抗体) expressions increased in the resistant group

  2. an SNP in ABCB1 (显示 ABCB1 抗体) (rs2032582: 2677G > T/A) was significantly associated with atorvastatin-induced liver injury (AILI) indicating that the G allele might be a risk factor for AILI in Japanese population

  3. impact of CYP4F2 (显示 CYP4F2 抗体), ABCB1 (显示 ABCB1 抗体), and GGCX (显示 GGCX 抗体) polymorphisms on bleeding episodes associated with acenocoumarol in Russian patients with atrial fibrillation

  4. Collectively, the data establish a hitherto unknown liaison among MDR1 (显示 TBC1D9 抗体), BMI1 (显示 BMI1 抗体) and TIP60 (显示 KAT5 抗体) and provide mechanistic insights into cisplatin-induced MDR1 (显示 TBC1D9 抗体) expression resulting in acquired cross-resistance against paclitaxel, doxorubicin and likely other anticancer drugs.

  5. High ABCB1 (显示 ABCB1 抗体) expression is associated with hepatocellular carcinoma.

  6. Our data suggest that the C1236T and G2677A/T SNPs in the MDR1 (显示 TBC1D9 抗体) gene are associated with Crohn's disease and the C1236T risk allele with a more severe course of disease in Algerian pediatric patients.

  7. ATPase (显示 DNAH8 抗体) measurements imply that DCV and Ho are similarly handled by ABCB1 (显示 ABCB1 抗体), whereas ABCG2 (显示 ABCG2 抗体) seems to transport DVC more effectively. In addition, we have developed an image-based high content microscopy screening method for simultaneous in situ measurement of the cellular activity and expression of the ABCG2 (显示 ABCG2 抗体) multidrug transporter

  8. These results show that multidrug resistant leukemia cell microparticle regulation of ABCC1 (显示 ABCC1 抗体) in recipient cells is governed by the transfer of both miR (显示 MLXIP 抗体)-326 and ABCB1 (显示 ABCB1 抗体) from donor cells

  9. he modulatory effect of acacetin-doxorubicin combination on doxorubicin influx and efflux was mediated through downregulation of MDR1 (显示 TBC1D9 抗体) treansporter in non-small-cell lung carcinoma (NSCLC) cells.

  10. An additional action of osimertinib that directly inhibits the function of ABCB1 (显示 ABCB1 抗体).

Malic Enzyme Complex, Mitochondrial (Mod2) 抗原简介

蛋白简介

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Gene names and symbols associated with Mod2

  • malic enzyme complex, mitochondrial (Mod2) 抗体
  • ATP binding cassette subfamily B member 1 (ABCB1) 抗体
  • ABC20 抗体
  • CD243 抗体
  • CLCS 抗体
  • GP170 抗体
  • Mdr 抗体
  • Mdr-1 抗体
  • MDR1 抗体
  • Mod-2 抗体
  • Mod-2r 抗体
  • Mod-2s 抗体
  • Mod2-r 抗体
  • Mod2-s 抗体
  • P-GP 抗体
  • PGY1 抗体

Protein level used designations for Mod2

malic enzyme complex, mitochondrial , malic enzyme, mitochondrial regulatory , malic enzyme, mitochondrial structural , P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , multidrug resistance protein 1

GENE ID SPECIES
110357 Mus musculus
5243 Homo sapiens
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