anti-Malic Enzyme Complex, Mitochondrial (Mod2) 抗体

The membrane-associated protein encoded by Mod2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. 再加上,我们可以发Malic Enzyme Complex, Mitochondrial 蛋白 (8)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
小鼠 Mod2 Mod2 110357  
Mod2 5243 P08183

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通过反应活性、应用领域、克隆类型和共轭标记 Mod2 抗体

特性 应用范围 宿主 克隆类型 标记
Human , ,


,

更多抗Malic Enzyme Complex, Mitochondrial的相互作用对抗体

Human Malic Enzyme Complex, Mitochondrial (Mod2) interaction partners

  1. ABCB1 polymorphisms may contribute to the blood pressure variation in Han Chinese population and the effect may be specific in females

  2. SMS (显示 SMS 抗体) regulates the expression and function of drug transporters P-gp (显示 ABCB4 抗体) and MRP2 (显示 ABCC2 抗体).

  3. BZML is a novel colchicine binding site inhibitor and overcomes multi-drug resistance in A549/Taxol cells by inhibiting P-gp (显示 ABCB4 抗体) function and inducing mitotic catastrophe.

  4. We have noted that the implication of C3435T variant on the risk of breast cancer was ethnicity-dependent. However, there is no evidence that ABCB1 (显示 ABCB1 抗体) C3435T polymorphism could play a role in susceptibility to breast cancer in Morocco.

  5. no significant clinical relevance between Pgp expression and osteosarcoma survival

  6. Meta-analysis found no evidence for ABCB1 (显示 ABCB1 抗体) C3435T and C1236T polymorphisms as risk factors for pediatric Acute Lymphoblastic Leukemia.

  7. ABCB1 (显示 ABCB1 抗体) gene polymorphisms in association with others risk factors contribute to anti-TB drug resistance, mainly ethambutol.

  8. For the first time, we demonstrated that MDR1 (显示 TBC1D9 抗体) rs1128503 polymorphisms were associated with systemic lupus erythematosus susceptibility in Chinese Guangxi population.

  9. multiple pathways, including MMP9 (显示 MMP9 抗体) cleavage and ubiquitinylation, mediated P-gp (显示 ABCB4 抗体) downmodulation.

  10. We also determined the effect of Pygo2 on the sensitivity of breast tumors resistant to doxorubicin in a mouse model. Finally, RNA samples from 64 paired patient tumors (before and after chemotherapy) highly and significantly overexpressed Pygo2 and/or MDR1 after treatment, thus underlining a pivotal role for the Pygo2-mediated Wnt/b-catenin pathway in the clinical chemoresistance of breast cancer.

Malic Enzyme Complex, Mitochondrial (Mod2) 抗原简介

蛋白简介

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Gene names and symbols associated with Mod2

  • malic enzyme complex, mitochondrial (Mod2) 抗体
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1 (ABCB1) 抗体
  • ABC20 抗体
  • CD243 抗体
  • CLCS 抗体
  • GP170 抗体
  • Mdr 抗体
  • Mdr-1 抗体
  • MDR1 抗体
  • Mod-2 抗体
  • Mod-2r 抗体
  • Mod-2s 抗体
  • Mod2-r 抗体
  • Mod2-s 抗体
  • P-GP 抗体
  • PGY1 抗体

Protein level used designations for Mod2

malic enzyme complex, mitochondrial , malic enzyme, mitochondrial regulatory , malic enzyme, mitochondrial structural , P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , multidrug resistance protein 1

GENE ID SPECIES
110357 Mus musculus
5243 Homo sapiens
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