anti-LIM Homeobox 4 (LHX4) 抗体

LHX4 encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. 再加上,我们可以发LHX4 试剂盒 (10)LHX4 蛋白 (4)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
LHX4 89884 Q969G2
LHX4 360858  
LHX4 16872 P53776
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Showing 10 out of 66 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
Cow 非结合性 WB <b>WB Suggested Anti-LHX4 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:12500<br><b>Positive Control: </b>721_B cell lysate 100 μL Log in to see 2至3个工作日
小鼠 非结合性 WB LHX4 monoclonal antibody (M06), clone 1C5 Western Blot analysis of LHX4 expression in LNCaP. 0.1 mg Log in to see 8至11个工作日
小鼠 非结合性 ELISA Detection limit for recombinant GST tagged LHX4 is approximately 0.1 ng/mL as a capture antibody. 0.1 mg Log in to see 8至11个工作日
非结合性 WB LHX4 Antibody (Center) (ABIN1881496) western blot analysis in HepG2 cell line lysates (35 µg/lane). This demonstrates the LHX4 antibody detected the LHX4 protein (arrow). 400 μL Log in to see 10至11个工作日
Bat 非结合性 ELISA, IHC (p), WB 50 μg Log in to see 7至9个工作日
Bat 非结合性 WB 50 μg Log in to see 7至9个工作日
小鼠 非结合性 EIA, IHC (p), WB 50 μg Log in to see 6至8个工作日
非结合性 IF, WB Western Blot analysis of LHX4 expression in transfected 293T cell line by LHX4 MaxPab polyclonal antibody.<br><br>Lane 1: LHX4 transfected lysate(43.10 KDa).<br>Lane 2: Non-transfected lysate.<br> LHX4 MaxPab rabbit polyclonal antibody. Western Blot analysis of LHX4 expression in human liver. 100 μg Log in to see 11至12个工作日
非结合性 IHC, IHC (p) Immunohistochemistry-Paraffin: Lhx4 Antibody [NBP2-15010] - Paraffin-embedded Colon ca, using antibody at 1:250 dilution. 0.1 mL Log in to see 8至11个工作日
小鼠 非结合性 IHC (p), ELISA, WB Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 7至9个工作日

通过反应活性、应用领域、克隆类型和共轭标记 LHX4 抗体

特性 应用范围 宿主 克隆类型 标记
Human , , , ,
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Rat (Rattus) ,

Mouse (Murine) ,

引用最多的anti-LHX4 抗体

  1. Human Polyclonal LHX4 Primary Antibody for WB - ABIN1881496 : Castinetti, Saveanu, Reynaud, Quentien, Buffin, Brauner, Kaffel, Albarel, Guedj, El Kholy, Amin, Enjalbert, Barlier, Brue: A novel dysfunctional LHX4 mutation with high phenotypical variability in patients with hypopituitarism. in The Journal of clinical endocrinology and metabolism 2008 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal LHX4 Primary Antibody for IF, WB - ABIN529948 : Hung, Hu, Ho, Chiu, Lee, Jeng, Shih, Lee: Downregulation of alpha-fetoprotein expression by LHX4: a critical role in hepatocarcinogenesis. in Carcinogenesis 2011 (PubMed)


Zebrafish LIM Homeobox 4 (LHX4) interaction partners

  1. Lhx3 (显示 LHX3 抗体) and Lhx4 have roles in suppressing Kolmer-Agduhr interneuron characteristics within zebrafish axial motoneurons

Human LIM Homeobox 4 (LHX4) interaction partners

  1. LHX4 Mutation is associated with Pituitary Deficits.

  2. The study identified 4 new LHX4 heterozygous allelic variants in patients with congenital hypopituitarism: W204X, delK242, N271S and Q346R.

  3. A novel homozygous mutation in LHX4 associated with a lethal phenotype, implying that recessive mutations in LHX4 may be incompatible with life.

  4. we found that LHX4 upregulated beta-catenin (显示 CTNNB1 抗体) levels in human colorectal cancer cell lines

  5. Data indicate that HESX1 (显示 HESX1 抗体), LHX4 and SOX3 (显示 SOX3 抗体) polymorphisms may be associated with pituitary stalk interruption syndrome (PSIS).

  6. This study is the first to describe, a gradual loss of ACTH (显示 POMC 抗体) in a patient carrying an LHX4 mutation.

  7. Variably penetrant pituitary insufficiency, including this severe and atypical presentation, can be correlated with LHX4 insufficiency and highlights the role of LHX4 for pituitary development.

  8. data indicate that LHX4 may act as a potential tumor suppressor in hepatocarcinogenesis, suggesting that targeting LHX4 to downregulate AFP (显示 AFP 抗体) might have therapeutic implications

  9. A novel HESX1 (显示 HESX1 抗体) causative mutation was found in a consanguineous family, and two LHX4 mutations were present in familial Pituitary stalk interruption syndrome.

  10. "Heterozygous splice site mutations within LHX4 are associated with combined pituitary hormone deficiency and isolated growth hormone deficiency... small sella turcica...persistent craniopharyngeal canal...ectopic posterior pituitary... " P. 207

Cow (Bovine) LIM Homeobox 4 (LHX4) interaction partners

  1. some polymorphisms in LHX4 are associated with growth traits at certain ages, and may be used as candidates for marker-assisted selection and management

Mouse (Murine) LIM Homeobox 4 (LHX4) interaction partners

  1. conditional deletion of Shh (显示 SHH 抗体) in the anterior hypothalamus results in a fully penetrant phenotype characterised by a complete arrest of (Rathke's pouch) RP development, with lack of Lhx3 (显示 LHX3 抗体)/Lhx4 expression in RP epithelium.

  2. We discovered that expression of Cdkn1a (显示 CDKN1A 抗体) is expanded dorsally in the pituitary primordium of both Lhx3 (显示 LHX3 抗体) and Lhx4 mutants. Lhx4 mutants exhibit reduced cyclin D1 (显示 CCND1 抗体) expression and have auxiliary pouch-like structures.

  3. X-ray crystal- and small-angle x-ray scattering-derived solution structures of an Lhx4.Isl2 (显示 ISL2 抗体) complex exhibit many similarities with that of Lhx3 (显示 LHX3 抗体).Isl1 (显示 ISL1 抗体); structural differences supported by mutagenic studies reveal differences in the mechanisms of binding.

  4. Lhx4 and Prop1 (显示 PROP1 抗体) have critical, but mechanistically different roles in specification and expansion of specialized anterior pituitary cells

  5. We conclude Sp1 (显示 SP1 抗体) directly regulates Lhx4 gene expression.

  6. Results show that Lhx3 (显示 LHX3 抗体) exhibits specific spatial and temporal expression in the mouse placenta, but that absence of both LHX3 (显示 LHX3 抗体) and 4 genes did not interfere with placental transport nor consistently with expression of target genes such as Gnrhr (显示 GNRHR 抗体).

  7. Successful purification and crystallization of an engineered complex comprising the LIM (显示 PDLIM5 抗体) domains of motor neuron protein Lhx4 and the Lim (显示 PDLIM5 抗体) binding domain of Isl2 (islet 2 (显示 ISL2 抗体) protein) are reported.

LHX4 抗原简介


This gene encodes a member of a large protein family which contains the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein is a transcription factor involved in the control of differentiation and development of the pituitary gland. Mutations in this gene cause combined pituitary hormone deficiency 4.

Gene names and symbols associated with anti-LIM Homeobox 4 (LHX4) 抗体

  • LIM homeobox 4 (LHX4) 抗体
  • LIM homeobox 4 (lhx4) 抗体
  • LIM homeobox 4 (Lhx4) 抗体
  • LIM homeobox protein 4 (Lhx4) 抗体
  • A330062J17Rik 抗体
  • CPHD4 抗体
  • Gsh-4 抗体
  • Gsh4 抗体
  • LHX4 抗体
  • si:dkeyp-35f11.3 抗体

Protein level used designations for anti-LIM Homeobox 4 (LHX4) 抗体

LIM homeobox 4 , LIM homeobox protein 4 , LIM/homeobox protein Lhx4 , LIM/homeobox protein Lhx4-like , LIM homeo box protein 4

469601 Pan troglodytes
571943 Danio rerio
100460807 Pongo abelii
89884 Homo sapiens
490300 Canis lupus familiaris
540797 Bos taurus
360858 Rattus norvegicus
776024 Gallus gallus
100727880 Cavia porcellus
101122876 Ovis aries
16872 Mus musculus
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