anti-Inosine Triphosphatase (ITPA) 抗体

The protein encoded by ITPA hydrolyzes inosine triphosphate and deoxyinosine triphosphate to the monophosphate nucleotide and diphosphate. 再加上,我们可以发Inosine Triphosphatase 蛋白 (24)Inosine Triphosphatase 试剂盒 (12)和数多这个蛋白质的别的产品。

列出全部抗体 基因 基因ID UniProt
ITPA 3704 Q9BY32
ITPA 311422 D3ZW55
ITPA 16434 Q9D892

antibodies-online.cn销售最多的anti-Inosine Triphosphatase 抗体

Showing 10 out of 80 products:

产品编号 适用 宿主 标记 应用范围 图像 规格 供应商 交付 价格 详细
非结合性 FACS, IF, IHC (p), WB Western blot analysis of ITPA Antibody (N-term) (ABIN651135) in A375 cell line lysates (35 µg/lane). ITPA (arrow) was detected using the purified polyclonal antibody. ITPA Antibody (N-term) (ABIN651135) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 5至8个工作日
非结合性 ELISA, IHC, WB 100 μL Log in to see 34至38个工作日
小鼠 非结合性 IHC, WB Western blot analysis of extracts of various cell lines, using ITPA antibody. 200 μL Log in to see 7至8个工作日
小鼠 非结合性 ELISA Detection limit for recombinant GST tagged ITPA is 3 ng/ml as a capture antibody. 100 μg Log in to see 29至34个工作日
非结合性 IHC (p), WB IHC-P Image ITPase antibody [N1C3] detects ITPase protein at cytosol on Ca922 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded Ca922 xenograft. ITPase antibody [N1C3] , dilution: 1:500. WB Image Sample(30 ug whole cell lysate) A:293T B:Hep G2 , 12% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 23至28个工作日
非结合性 WB ITPA Antibody (C-term)  western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the ITPA antibody detected the ITPA protein (arrow). 400 μL Log in to see 5至8个工作日
非结合性 IHC, IHC (p), WB Western Blot: ITPA Antibody [NBP1-32494] - Sample(30 ug whole cell lysate)A:293TB:Hep G2 (GTX27900)12% SDS PAGE, antibody diluted at 1:1000. 100 μL Log in to see 25至31个工作日
Alexa Fluor 594 IF (p)   100 μL Log in to see 14至17个工作日
Alexa Fluor 647 IF (p)   100 μL Log in to see 14至17个工作日
HRP IHC (p), WB   100 μL Log in to see 14至17个工作日

通过反应活性、应用领域、克隆类型和共轭标记 ITPA 抗体

特性 应用范围 宿主 克隆类型 标记
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引用最多的anti-Inosine Triphosphatase 抗体

  1. Human Monoclonal ITPA Primary Antibody for ELISA - ABIN517268 : Vroemen, Munnix, Bakker, Bierau, Huts, Leers: A novel multiparameter flow cytometric assay for inosine triphosphatase expression analysis in leukocytes. in Cytometry. Part A : the journal of the International Society for Analytical Cytology 2012 (PubMed)

更多抗Inosine Triphosphatase的相互作用对抗体

Human Inosine Triphosphatase (ITPA) interaction partners

  1. Inosine triphosphatase (IPTA) rs1127354 variants but not rs7270101 were found in Chinese patients infected with chronic hepatitis C. IPTA rs1127354 variants and related ITPase were not only related with ribavirin-induced hemolytic anemia but also directly affected the virological response to pegylated interferon (显示 IFNA 抗体) plus ribavirin combination therapy in Chinese chronic hepatitis C virus-infected patients.

  2. This study concluded that HIV-infection seems to be interfering with the nucleotide metabolism in leukocytes, including CD4 (显示 CD4 抗体) lymphocytes, by decreasing ITPase expression, independently of ITPA genotype.

  3. A high prevalence of the ITPA polymorphisms associated with ribavirin-induced hemolytic anemia was found in Mexican Native Amerindians.

  4. ITPA gene is associated with protection of anemia in patients with chronic hepatitis during antiviral therapy.

  5. We concluded that ITPase activity plays an important function and that ATP concentration changes due to therapy are related to the Hb decreasing mechanism in the early period of therapy with HCV treatment

  6. The aim of the study was to investigate frequencies of TPMT (显示 TPMT 抗体) and ITPA polymorphisms in Lithuanian inflammatory bowel disease patients and analyze their association with azathioprine-related adverse events.

  7. ITPA polymorphism was associated with RBV-induced anemia and thrombocytopenia in Egyptian patients with hepatitis C virus genotype 4 infection.

  8. Hyperbilirubinemia develops at early time points after simeprevir administration in most cases and is dependent on the ITPA genotype.

  9. Genetic variants in inosine triphosphatase (ITPA) gene have been linked to the haemolytic anaemia induced by peg (显示 PAEP 抗体)-interferon (显示 IFNA 抗体) and ribavirin treatment.

  10. The association of IL28B (显示 IL28B 抗体) and APOH (显示 APOH 抗体) single nucleotide polymorphisms (SNPs) with sustained virological response and of ITPA SNPs with anemia related phenotypes.

Mouse (Murine) Inosine Triphosphatase (ITPA) interaction partners

  1. In the mouse genome, we found one processed Itpa gene-like sequence and two processed Itpa pseudogenes as well as the Itpa gene itself with introns.

  2. The role of ITPase in mice is to exclude ITP from the ATP pool, and the main target substrate of this enzyme is rITP

Inosine Triphosphatase (ITPA) 抗原简介


This gene encodes an inosine triphosphate pyrophosphohydrolase. The encoded protein hydrolyzes inosine triphosphate and deoxyinosine triphosphate to the monophosphate nucleotide and diphosphate. This protein, which is a member of the HAM1 NTPase protein family, is found in the cytoplasm and acts as a homodimer. Defects in the encoded protein can result in inosine triphosphate pyrophosphorylase deficiency which causes an accumulation of ITP in red blood cells. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with ITPA

  • inosine triphosphatase (itpa) 抗体
  • inosine triphosphatase (LOC100345066) 抗体
  • inosine triphosphatase (LOC733043) 抗体
  • inosine triphosphatase (LOC100157088) 抗体
  • inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (ITPA) 抗体
  • inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (Itpa) 抗体
  • inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (itpa) 抗体
  • LOC100283993 (pco148511) 抗体
  • nucleoside-triphosphatase, cancer-related (NTPCR) 抗体
  • 2010016I08Rik 抗体
  • AU020102 抗体
  • C1orf57 抗体
  • C20orf37 抗体
  • DDBDRAFT_0215619 抗体
  • DDBDRAFT_0238062 抗体
  • DDB_0215619 抗体
  • DDB_0238062 抗体
  • dJ794I6.3 抗体
  • HCR-NTPase 抗体
  • HLC14-06-P 抗体
  • Itp 抗体
  • ITPase 抗体
  • NTPase 抗体
  • RP4-678E16.2 抗体
  • si:ch73-18j6.1 抗体
  • si:dkey-19f21.1 抗体

Protein level used designations for ITPA

inosine triphosphate pyrophosphatase , inosine triphosphatase , ITPase , NTPase , inosine triphosphatase-A , inosine triphosphate pyrophosphohydrolase , non-canonical purine NTP pyrophosphatase , non-standard purine NTP pyrophosphatase , nucleoside-triphosphate diphosphatase , putative oncogene protein HLC14-06-P , nucleoside-triphosphate pyrophosphatase , nucleoside triphosphate pyrophosphatase , inosine triphosphatase A , Non-canonical purine NTP pyrophosphatase , Non-standard purine NTP pyrophosphatase , Nucleoside-triphosphate diphosphatase , Nucleoside-triphosphate pyrophosphatase , Inosine triphosphatase , PCO148511_ov , hypothetical protein , pco148511(169) , cancer-related nucleoside-triphosphatase , human cancer-related NTPase , nucleoside triphosphate phosphohydrolase , nucleoside-triphosphatase C1orf57

8625642 Dictyostelium discoideum AX4
100345066 Oryctolagus cuniculus
733043 Bombyx mori
100157088 Sus scrofa
3704 Homo sapiens
311422 Rattus norvegicus
16434 Mus musculus
613653 Bos taurus
424390 Gallus gallus
735008 Xenopus laevis
557834 Danio rerio
100283993 Zea mays
84284 Homo sapiens
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