Fat Mass and Obesity-Associated (FTO) ELISA试剂盒

FTO is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of FTO is not known. 再加上,我们可以发FTO 抗体 (143)FTO 蛋白 (10)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
FTO 79068 Q9C0B1
FTO 26383 Q8BGW1
FTO 291905 Q2A121
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产品编号 适用 灵敏度 范围 图像 规格 供应商 交付 价格 详细
0.156-10 ng/mL 100 Tests Log in to see 2至3个工作日
0.156-10 ng/mL   96 Tests Log in to see 2至3个工作日
小鼠 20 pg/mL 0.156-10 ng/mL   96 Tests Log in to see 6至8个工作日

适于 FTO 相互作用对的更多 ELISA 试剂盒

Human Fat Mass and Obesity-Associated (FTO) interaction partners

  1. The age of diabetes was not affect by the tested FTO polymorphisms (rs9939609 , rs1421085, and rs9930506).

  2. Infants carrying the GG genotype of the LEP (显示 LEP ELISA试剂盒) rs7799039 polymorphism were 2.12 times more likely to be born large for gestational age (LGA (显示 GLS2 ELISA试剂盒)) than those carrying the GA + AA genotypes. Newborns carrying the TG or GG genotype of the ADIPOQ rs2241766 polymorphism were 1.88 times more likely to be born LGA (显示 GLS2 ELISA试剂盒) than those carrying the TT genotype. No association was found between the FTO gene polymorphism and newborn weight status.

  3. FTO obesity risk allele is associated with differential neural processing of food images.

  4. Data confirm the association between the FTO first intron polymorphism and the presence of type 2 diabetes mellitus in the Slavonic (Czech) population. The same variant is likely to be associated with development of chronic complications of diabetes mellitus, especially with diabetic neuropathy and diabetic kidney disease in either T2DM or both T1DM and T2DM.

  5. This study demonstrated that the rs9939609 (FTO) polymorphism showed a relationship with obesity in the population studied and an interaction with cardiorespiratory fitness (CRF (显示 CRH ELISA试剂盒)). Students with low levels of CRF (显示 CRH ELISA试剂盒) and the AA genotype have a higher risk of being overweight/obese.

  6. Data show that the splicing effects of alpha-ketoglutarate dependent dioxygenase FTO are dependent on the catalytic activity in vivo and are mediated by N6-methyladenosine (m6A (显示 GPM6A ELISA试剂盒)).

  7. FTO variants not only were associated with T2DM, but also some variants had a strong association with apelin (显示 APLN ELISA试剂盒) and androgenic hormones profile.

  8. FTO and near MC4R (显示 MC4R ELISA试剂盒) variants are associated with obesity measures in Sri (显示 SRI ELISA试剂盒) Lankan populations...

  9. Results suggest that the hypomorphic FTO p.A134T variant is associated with thiopurine-induced leukopenia in South Korean patients with inflammatory bowel disease.

  10. The FTO gene polymorphism, rs9939609, was found to be associated with insulin resistance, insulin, triglyceride and adiponectin levels in obese patients with TT variant

Mouse (Murine) Fat Mass and Obesity-Associated (FTO) interaction partners

  1. Contextual fear conditioning decreased FTO levels in neurons from the hippocampus.

  2. The involvement of mTOR (显示 FRAP1 ELISA试剂盒)-PGC-1alpha (显示 PPARGC1A ELISA试剂盒) pathway in the connection between FTO and muscle differentiation is displayed.

  3. In vivo experiments revealed that Fto(-/-) and Fto(+/-) mice were more susceptible to thiopurine-induced myelosuppression than wild-type mice.

  4. propose that PKCbeta acts to suppress the degradation of FTO protein and reveals the associated role of PKCbeta and FTO in adipogenesis, suggesting a new pathway that affects the development of obesity and metabolic diseases

  5. the results of this study indicate that the effects of FTO-associated SNPs on energy homeostasis are due in part to the effects of these genetic variations on hypothalamic FTO, RPGRIP1L (显示 RPGRIP1L ELISA试剂盒), and possibly other genes.

  6. FTO may have a deleterious role in hepatic cells during lipotoxic conditions, and up-regulation of FTO may contribute to the increased liver damage in non-alcoholic steatohepatitis

  7. Fto deficiency affects the gene and miR130/miR378 expression involved in brown adipogenesis and browning of white adipose tissue in mice.

  8. Here we show that FTO expression is increased after ureteral obstruction and renal fibrosis.

  9. Taken together, the results suggest that Fto regulates the proliferation and differentiation of 3T3-L1 cells via multiple mechanisms, including PPARgamma (显示 PPARG ELISA试剂盒) and PI3K/Akt (显示 AKT1 ELISA试剂盒) signaling.

  10. These results reveal that FTO regulates fatty acid mobilization in adipocytes and thus body weight in part through posttranscriptional regulation of Angptl4 (显示 ANGPTL4 ELISA试剂盒).

Pig (Porcine) Fat Mass and Obesity-Associated (FTO) interaction partners

  1. In this study, the authors characterise the nucleotide variability and haplotype diversity of the porcine fat mass and obesity-associated (FTO) gene in breeds having different predispositions to fat deposition traits.

  2. In pig, the FTO gene influences back fat depth in the commercial populations.

  3. This study will provide clues for obtaining a better understanding of the porcine FTO gene function.

  4. The results of the association analyses confirmed the effect of the FTO mutation on obesity-related traits in the Italian Duroc pigs (P < 0.01) and in the commercial pigs.

  5. The porcine fat mass and obesity associated (FTO) gene is associated with fat deposition in Italian Duroc pigs.

Cow (Bovine) Fat Mass and Obesity-Associated (FTO) interaction partners

  1. 34 FTO polymorphisms revealed significant association of FTO variants with lean meat percentage in Simmental and Brown cattle breeds.

  2. association signals not only provided evidence for at least two causative mutations in the FTO locus with a functional effect on milk but also milk protein (显示 CSN2 ELISA试剂盒) yield

  3. Haplotype frequencies and linkage disequilibrium (LD) coefficients of FTO single nucleotide polymorphisms in three Chinese indigenous cattle breeds were analyzed.

FTO 抗原简介

Antigen Summary

This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.

Gene names and symbols associated with FTO

  • FTO, alpha-ketoglutarate dependent dioxygenase (FTO) 抗体
  • fat mass and obesity associated (Fto) 抗体
  • FTO, alpha-ketoglutarate dependent dioxygenase (Fto) 抗体
  • fat mass and obesity associated L homeolog (fto.L) 抗体
  • AW743446 抗体
  • mKIAA1752 抗体
  • RGD1305121 抗体

Protein level used designations for FTO

alpha-ketoglutarate-dependent dioxygenase FTO , fat mass and obesity-associated protein , protein fto , protein fatso , fat mass and obesity associated protein , Protein fatso

79068 Homo sapiens
26383 Mus musculus
478125 Canis lupus familiaris
100127165 Sus scrofa
291905 Rattus norvegicus
100060565 Equus caballus
618622 Bos taurus
100125353 Ovis aries
447305 Xenopus laevis
100173222 Pongo abelii
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