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The Fos gene family consists of 4 members FOSL1, and FOSL2. 再加上，我们可以发FOSL1 抗体 (89) 和 FOSL1 蛋白 (10)和数多这个蛋白质的别的产品。
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Mouse (Murine) FOSL1 ELISA Kit - ABIN1053820
Chen, Wang, Chen, Zhang, Shen, Zhang, Chen: Activation of Toll-like receptors by intestinal microflora reduces radiation-induced DNA damage in mice. in Mutation research. Genetic toxicology and environmental mutagenesis 2014
Study shows that FOSL1 is the main immediate early AP-1 (显示 JUN ELISA试剂盒) member induced by melanoma oncogenes; found that FOSL1 is involved in melanoma cell migration as well as cell proliferation and anoikis-independent growth.
a Fra-1-miR (显示 MLXIP ELISA试剂盒)-134 axis drives a positive feedback loop that amplifies ERK (显示 EPHB2 ELISA试剂盒)/JNK (显示 MAPK8 ELISA试剂盒) signaling and reduces chemosensitivity in ovarian cancer cells.
PKCtheta (显示 PRKCQ ELISA试剂盒);-induced phosphorylations control the ability of Fra-1 to stimulate gene expression and breast cancer cell migration.
Multivariate analysis identified Fra-1 as an independent prognostic factor. Fra-1 may be involved in the progress of hepatocellular carcinoma and could be a promising molecular candidate in the diagnosis and treatment of hepatocellular carcinoma.
Up-regulation of Fra-1 appeared in retinal ganglion cells following light-induced retina damage.
HGF (显示 HGF ELISA试剂盒)-induced FRA1 activation is associated with the fibrosis-dependent development of Hepatocellular Carcinoma.
Our results demonstrate that Fra-1 is an important determinant of the metastatic potential of human colon cancer cells, and that the Fra-1 classifier can be used as a prognostic predictor in colon cancer patients.
Results suggest that Fra-1 is upregulated in lung cancer tissues and functions by affecting the P53 (显示 TP53 ELISA试剂盒) signaling pathway.
SIRT1 (显示 SIRT1 ELISA试剂盒) expression correlated positively with Fra-1 expression, metastasis and overall survival in patients with colorectal cancer
We identified and confirmed that Fra-1 affected the expression level of CTTN (显示 CTTN ELISA试剂盒) and EZR (显示 EZR ELISA试剂盒) in vitro through LC-MS/MS analyses and western blot technology.
NF-kappaB (显示 NFKB1 ELISA试剂盒) and c-Jun (显示 JUN ELISA试剂盒) coregulate lipopolysaccharide-induced Fra-1 transcription.
Upon stimulation with poly(I:C), malaria parasite-infected red blood cells (iRBCs), or vesicular stomatitis virus (VSV), FOSL1 "translocated" from the nucleus to the cytoplasm, where it inhibited the interactions between TNF receptor-associated factor 3 (TRAF3 (显示 TRAF3 ELISA试剂盒)), TIR domain-containing adapter inducing IFN-beta (显示 IFNB1 ELISA试剂盒) (TRIF (显示 RNF138 ELISA试剂盒)), and Tank-binding kinase 1 (TBK1 (显示 TBK1 ELISA试剂盒)) via impairing K63-linked polyubiquitination of TRAF3 (显示 TRAF3 ELISA试剂盒) and TRIF (显示 RNF138 ELISA试剂盒).
Adipose-derived stromal cells overexpressing Fra-1 effectively protect against osteoarthritis.
Overexpression of Fosl1, which encodes a component of the AP-1 (显示 JUN ELISA试剂盒) transcription factor complex, in osteoblasts significantly blocked malleal capillary narrowing.
Fra-1 gene expression is activated in response lipopolysaccharide induced lung-injury in mice.
Data suggest that expression of Fra1 (fos-related antigen 1) in preadipocytes is up-regulated by arachidonic acid (AA) during late stages of adipogenesis; however, in early stage of adipogenesis, AA inhibits adipogenesis via Fra1-dependent mechanism.
Fra-1 plays a key role in promoting chronic CS-induced lung macrophagic inflammation in vivo
we demonstrate that Fra1 negatively controls plasma cell differentiation by repressing Blimp1 (显示 PRDM1 ELISA试剂盒) expression.
observations suggest that MyoD (显示 MYOD1 ELISA试剂盒) and pRb (显示 PGR ELISA试剂盒) work together cooperatively at the level of the intronic enhancer of Fra-1 during terminal cell cycle arrest
findings, based on a definitive genetic mouse model provide fundamental insights into mammary duct maturation and homeostasis and reveal that Scrib (显示 SCRIB ELISA试剂盒) loss activates a MAPK (显示 MAPK1 ELISA试剂盒)/Fra1 pathway that alters mammary progenitor activity
The Fos gene family consists of 4 members FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.
, fos-related antigen 1
, FOS-like antigen 1