Cytochrome B-245, beta Polypeptide (CYBB) ELISA试剂盒

Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. 再加上,我们可以发CYBB 抗体 (115)CYBB 蛋白 (6)和数多这个蛋白质的别的产品。

list all ELISA KIts 基因 基因ID UniProt
CYBB 1536 P04839
CYBB 13058 Q61093
CYBB 66021  

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0.055 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 7至10个工作日
¥3,480.75
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小鼠 11.75 pg/mL 47-3000 pg/mL Typical standard curve 96 Tests Log in to see 9至12个工作日
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大鼠 0.057 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 7至10个工作日
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引用最多的CYBB ELISA试剂盒

  1. Human CYBB ELISA Kit for Sandwich ELISA - ABIN418998 : Tassone, Perticone, Sciacqua, Mafrici, Settino, Malara, Mollace, Sesti, Perticone: Low dose of acetylsalicylic acid and oxidative stress-mediated endothelial dysfunction in diabetes: a short-term evaluation. in Acta diabetologica 2015 (PubMed)

  2. Rat (Rattus) CYBB ELISA Kit for Sandwich ELISA - ABIN433568 : Du, Wang, Wang: Role of RhoA/MERK1/ERK1/2/iNOS signaling in ocular ischemic syndrome. in Graefe's archive for clinical and experimental ophthalmology 2016 (PubMed)

适于 CYBB 相互作用对的更多 ELISA 试剂盒

Zebrafish Cytochrome B-245, beta Polypeptide (CYBB) interaction partners

  1. The nox1 (显示 NOX1 ELISA试剂盒), nox2/cybb expression in zebrafish during early nervous system development from 12 to 48 hours post fertilization

Rabbit Cytochrome B-245, beta Polypeptide (CYBB) interaction partners

  1. Data indicate that NADPH oxidase (显示 NOX1 ELISA试剂盒) NOx2 inhibition attenuates endoplasmic reticulum (ER) stress and apoptosis.

Human Cytochrome B-245, beta Polypeptide (CYBB) interaction partners

  1. NOX2, NOX4 (显示 NOX4 ELISA试剂盒), and mitochondrial-derived reactive oxygen species contribute to angiopoietin-1 (显示 ANGPT1 ELISA试剂盒) signaling and angiogenic responses in endothelial cells.

  2. PFK-2 (显示 PFKFB3 ELISA试剂盒) seems to be a strategic element that links NADPH oxidase (显示 NOX1 ELISA试剂盒) activation and glycolysis modulation, and, as such, is proposed as a potential therapeutic target in inflammatory diseases.

  3. data support NOX2 as a critical component of the suppressive machinery of CD8 (显示 CD8A ELISA试剂盒) Tregs and suggest that repairing NOX2 deficiency in these cells may protect older individuals from tissue-destructive inflammatory disease, such as large-vessel vasculitis.

  4. CD8 (显示 CD8A ELISA试剂盒)+ T cells in close contact with target T cells release NADPH oxidase 2-containing microvesicles that inhibit TCR activation by elevating ROS (显示 ROS1 ELISA试剂盒) and thereby reducing phosphorylation of the TCR-associated kinase ZAP70 (显示 ZAP70 ELISA试剂盒).

  5. Thioredoxin (显示 TXN ELISA试剂盒) attenuates oxidized low-density lipoprotein induced oxidative stress in human umbilical vein endothelial cells by reducing NOX2-NOX4 (显示 NOX4 ELISA试剂盒) activity.

  6. Nox4 (显示 NOX4 ELISA试剂盒)-derived H2O2 in part activates Nox2 to increase mitochondrial ROS (显示 ROS1 ELISA试剂盒) via pSer36-p66Shc (显示 SHC1 ELISA试剂盒), thereby enhancing VEGFR2 (显示 KDR ELISA试剂盒) signaling and angiogenesis in endothelial cells.

  7. Cytochrome b558 (显示 CYBA ELISA试剂盒) also traffics from a lysosomal pool to phagosomes and this is required to replenish oxidatively damaged NOX2.

  8. Nox4 (显示 NOX4 ELISA试剂盒) should contribute to the pathological processes insubarachnoid hemorrhage(SAH (显示 ACSM3 ELISA试剂盒))-induced early brain injury (EBI (显示 TBL1X ELISA试剂盒)), and there was not an overlay effect of Nox2 inhibition and Nox4 (显示 NOX4 ELISA试剂盒) inhibition on preventing SAH (显示 ACSM3 ELISA试剂盒)-induced EBI (显示 TBL1X ELISA试剂盒).

  9. NADPH oxidase (显示 NOX1 ELISA试剂盒) promotes Parkinsonian phenotypes by impairing autophagic flux in an mTORC1-independent fashion in a cellular model of Parkinson's disease

  10. TLR4 (显示 TLR4 ELISA试剂盒)- and TLR2 (显示 TLR2 ELISA试剂盒)-induced IRAK (显示 IRAK1 ELISA试剂盒)-ERK (显示 EPHB2 ELISA试剂盒) pathway cross-talks with p67phox (显示 NCF2 ELISA试剂盒)-Nox-2 for reactive oxygen species generation, thus regulating IL-1beta (显示 IL1B ELISA试剂盒) transcription and processing in monocytic cells.

Cow (Bovine) Cytochrome B-245, beta Polypeptide (CYBB) interaction partners

  1. Data indicate that the efficiency of NADPH oxidase (显示 NOX1 ELISA试剂盒) enzymatic activity is higher at endoplasmic reticulum (ER).

  2. A p47(phox) and Src kinase (显示 CSK ELISA试剂盒) activation of peroxide production by Nox2 appears to be an important contributor to vascular contractile mechanisms mediated through activation of protein kinase C (显示 PKC ELISA试剂盒)

Mouse (Murine) Cytochrome B-245, beta Polypeptide (CYBB) interaction partners

  1. Redox-dependent regulation of EGFR (显示 EGFR ELISA试剂盒) activation in airway epithelial cells was found to strongly depend on activation of either DUOX1 (显示 DUOX1 ELISA试剂盒) or NOX2.

  2. NOX2 signaling in macrophages participates in the pathogenesis of obesity, and reinforce a key role for macrophage inflammation in diet-induced metabolic and neurologic decline

  3. Studies in knockout and knock-in mice showed that the phospholipase A2 (显示 YWHAZ ELISA试剂盒) activity of peroxiredoxin 6 (显示 PRDX6 ELISA试剂盒) activates NOX2 in cultured pulmonary endothelial cells and alveolar macrophages, clarifying the metabolism of lysophosphatidyl chold to lysophosphatidic acid.

  4. NOX2 knockout mice had significantly lower blood pressure than littermate controls, with both endothelial cells and myeloid cells having a deficiency in NOX2.

  5. Data show that pan-NOX-inhibitor APX (显示 SHROOM1 ELISA试剂盒)-115 treatment decreased NADPH oxidase (显示 NOX1 ELISA试剂盒) (Nox) Nox1 (显示 NOX1 ELISA试剂盒), Nox2, and Nox4 (显示 NOX4 ELISA试剂盒) protein expression in the kidney.

  6. NOX2 regulates proinflammatory TLR signaling and alveolar remodeling induced by a single dose of lipopolysaccharides.

  7. a deficiency in MyD88 (显示 MYD88 ELISA试剂盒) or CybB is associated with impaired bacterial clearance and increased granuloma formation in the lung.

  8. NOX2 isoform was first discovered as a component of the oxidative burst in neutrophils and is a complex consisting of several cytosolic subunits (p47phox (显示 NCF1 ELISA试剂盒), p67phox (显示 NCF2 ELISA试剂盒), p40phox (显示 NCF4 ELISA试剂盒), and Rac1 or Rac2 (显示 RAC2 ELISA试剂盒)) and a membrane-associated cytochrome b558 (显示 CYBA ELISA试剂盒) reductase made up of gp91phox and p22phox (显示 CYBA ELISA试剂盒) subunits.

  9. Macrophage-produced HMGB1 (显示 HMGB1 ELISA试剂盒) leads to aortic inflammation and acts as a trigger for CD4 (显示 CD4 ELISA试剂盒)(+) T-cell-produced IL-17 (显示 IL17A ELISA试剂盒) during abdominal aortic aneurysm formation. HMGB1 (显示 HMGB1 ELISA试剂盒) release is dependent on Nox2 activation, which can be inhibited by MSCs leading to attenuation of proinflammatory cytokines and protection against AAA (显示 AAAS ELISA试剂盒) formation.

  10. NOX2 is important for ROS (显示 ROS1 ELISA试剂盒) generation induced by both the GPCR (显示 GPBAR1 ELISA试剂盒) and the GPVI (显示 GP6 ELISA试剂盒)/ITAM signaling pathways in blood platelets.

Pig (Porcine) Cytochrome B-245, beta Polypeptide (CYBB) interaction partners

  1. sub-vasomotor concentration of ET-1 (显示 EDN1 ELISA试剂盒) leads to vascular dysfunction by impairing endothelium-dependent NO-mediated dilation via p38 (显示 MAPK14 ELISA试剂盒) kinase-mediated production of superoxide from NADPH oxidase (显示 NOX1 ELISA试剂盒) following ETA receptor activation

  2. Reactive oxygen species generated by NADPH oxidase (显示 NOX1 ELISA试剂盒) contribute to the aberrant pulmonary arterial responses in piglets exposed to 3 days of hypoxia.

  3. Upregulation of PPAR-gamma (显示 PPARG ELISA试剂盒) and NADPH (显示 NQO1 ELISA试剂盒) oxidases are involved in restenosis.

CYBB 抗原简介

Antigen Summary

Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase\; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.

Gene names and symbols associated with CYBB

  • cytochrome b-245, beta polypeptide (chronic granulomatous disease) (cybb) 抗体
  • cytochrome b-245, beta polypeptide (cybb) 抗体
  • cytochrome b-245, beta polypeptide (chronic granulomatous disease) (CYBB) 抗体
  • cytochrome b-245, beta polypeptide (CYBB) 抗体
  • cytochrome b-245 beta polypeptide (CYBB) 抗体
  • cytochrome b-245, beta polypeptide (Cybb) 抗体
  • NADPH oxidase heavy chain subunit (GP91-PHOX) 抗体
  • AMCBX2 抗体
  • C88302 抗体
  • Cgd 抗体
  • CGD91-phox 抗体
  • CYBB 抗体
  • Cyd 抗体
  • GP91-1 抗体
  • Gp91-phox 抗体
  • GP91PHOX 抗体
  • NOX1 抗体
  • Nox2 抗体
  • p91-PHOX 抗体
  • zgc:64144 抗体

Protein level used designations for CYBB

cytochrome b-245, beta polypeptide , gp91 , NADPH oxidase 2 , cytochrome b-245, beta polypeptide (chronic granulomatous disease) , Cytochrome b-245 heavy chain , NADPH oxidase heavy chain subunit , NADPH oxidase 1 , NADPH oxidase flavocytochrome b subunit , cytochrome b-245 heavy chain , gp91-phox , CGD91-phox , cytochrome b(558) subunit beta , cytochrome b558 subunit beta , heme-binding membrane glycoprotein gp91phox , neutrophil cytochrome b 91 kDa polypeptide , p22 phagocyte B-cytochrome , superoxide-generating NADPH oxidase heavy chain subunit , gp91-1 , endothelial type gp91-phox , predicted NADPH oxidase-2

GENE ID SPECIES
393386 Danio rerio
595081 Xenopus (Silurana) tropicalis
696542 Macaca mulatta
444353 Xenopus laevis
100036757 Ovis aries
100270807 Salmo salar
100008801 Oryctolagus cuniculus
1536 Homo sapiens
418581 Gallus gallus
281112 Bos taurus
13058 Mus musculus
66021 Rattus norvegicus
491825 Canis lupus familiaris
397108 Sus scrofa
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