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抗Human Phospholipase C delta 3 抗体:
抗Mouse (Murine) Phospholipase C delta 3 抗体:
抗Rat (Rattus) Phospholipase C delta 3 抗体:
Results identified an interaction between PLCD3 and FLOT2 (显示 FLOT2 抗体). Inhibition of PLCD3 expression impaired the malignant potential of nasopharyngeal carcinoma (NPC (显示 NPC1 抗体)) cells, by restraining its growth, proliferation, mobility and migration. This study demonstrated that PLCD3 may be an oncogenic protein in NPC (显示 NPC1 抗体) and that it plays an important role in the progression of NPC (显示 NPC1 抗体) partially by interacting with Flot2 (显示 FLOT2 抗体).
In mo (显示 PLCD1 抗体)use, Plcd1 and Plcd3 may act together in murine hair follicles.
Data are consistent with the idea that phospholipase C (显示 PLC 抗体) d1 and d3 isoforms support the growth and migration of normal and neoplastic mammary epithelial cells in vitro.
Plcd1 (显示 PLCD1 抗体) and Plcd3 have synergistic effects on the murine hair follicle in specific regions of the body surface.
These results indicate that PLCdelta3 could participate in stability of microvilli structure via regulating and anchoring of Myo6 (显示 MYO6 抗体) to plasma membrane.
PLCdelta3 negatively regulates RhoA (显示 RHOA 抗体) expression, inhibits RhoA (显示 RHOA 抗体)/Rho kinase (显示 ROCK2 抗体) signaling, and thereby promotes neurite extension.
double disruption of PLCd1 (显示 PLCD1 抗体) and PLCd3 results in embryonic lethality because of insufficient vasculariztion of the placenta.
This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate the second messengers diacylglycerol and inositol 1,4,5-trisphosphate (IP3). Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca(2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids.
phospholipase C delta 3
, phospholipase C, delta 3
, 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3
, 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3
, PLC delta3
, phosphoinositide phospholipase C-delta-3
, phospholipase C-delta-3